SUPERIOR COURT OF CALIFORNIA COUNTY OF SANTA CLARA PALO ALTO COURTHOUSE ‘THE PEOPLE OF THE STATE OF CALIFORNIA, B47 GOs FELONY COMPLAINT CASE SUMMARY Plaintiff, DANO: 141128555 CEN 14054550 XO BAIL 12/01/2014 vs. XIANGYU OUYANG (11/02/1988), 119 QUILLEN CT APT. # 401 STANFORD CA 94305 Defendant(s). CASE SUMMARY Count Charge Charge Range Defendant 1 PC347(a) 24-5 ‘Xiangyu Ouyang 2 PC347(a) 24-5 Xiangyu Ouyang 3 PC347(a) 24-5 Xiangyu Ouyang 4 PC347(a) 24-5 Xiangyu OuyangSUPERIOR COURT OF CALIFORNIA COUNTY OF SANTA CLARA PALO ALTO COURTHOUSE. ‘THE PEOPLE OF THE STATE OF CALIFORNIA, vienis, | B14 7G04% FELONY COMPLAINT DANO: 141128555 vs. CEN 14054550 XO BAIL 12/01/2014 XIANGYU OUYANG (11/02/1988), 119 QUILLEN CT APT. #401 STANFORD CA 94305 Fl L Ep Defendant(s). nov 26 2048 ened isi . IO H, YAMASAKL ‘The undersigned is informed and believes that: Serer ole a we erin COUNT 1 (On or about September 1, 2014, in the County of Sania Clara, State of California, the crime of POISONING ANY FOOD, DRINK OR MEDICINE, in violation of PENAL CODE SECTION 347(2), a Felony, was committed by XIANGYU OUYANG who did willfully mingle 2 harmful substance, paraformaldehyde with a drink, water, and the defendant knew and should have known that the drink would be taken by a human being to his/her injury. COUNT 2 On or about November 10, 2014, in the County of Santa Clara, State of California, the crime of POISONING ANY FOOD, DRINK OR MEDICINE, in violation of PENAL CODE SECTION 347(a), 2 Felony, was committed by XIANGYU OUYANG who did willfully mingle a harmful substance, paraformaldehyde with a drink, water, and the defendant knew and should have known that the drink would be taken by a human being to his/her injury.COUNT 3 On or about October 14, 2014, in the County of Santa Clara, State of California, the crime of POISONING ANY FOOD, DRINK. OR MEDICINE, in violation of PENAL CODE SECTION 347(a), a Felony, was committed by XIANGYU OUYANG who did willfully mingle a harmful substance, paraformaldehyde with a drink, water, and the defendant knew and should have known that the drink ‘would be taken by a human being to his‘aer injury. COUNT 4 On or about November 6, 2014, in the County of Santa Clara, State of California, the crime of POISONING ANY FOOD, DRINK OR MEDICINE, in violation of PENAL CODE SECTION 347(a), a Felony, was committed by XIANGYU OUYANG who did willfully mingle a harmful substance, paraformaldehyde with a drink, water, and the defendant knew and should have known that the drink would be taken by a human being to his/her injury. ‘Any defendant, including a juvenile, woo is convicted of and pleads guilty and no contest to any felony offense, including any attempt to commit the offense, charged in this complaint or information is required to provide buccal swab samples, right thumbprints and a full palm print impression of each hand, and any blood specimens or other biological samples required pursuant to the DNA and Forensic Identification Database and Data Bank Act of 1998 and Penal Code section 296, et seq. Farther, attached and incorporated by reference ere official reports and documents of a law enforcement agency which the complainant believes establish probable cause for the pretrial restraint of defendant XIANGYU OUYANG, for the above-listed crimes.‘Complainant therefore requests that the defendant(s) be dealt with according to law. certify under penalty of perjury that the above is true and correct, Executed on November 26, 2014, in SANTA CLARA County, California. Lima yeasbé Officer Mike Kim K8866 (Officer Mike Kim K8866) STAN (650) 723-9633 143160081U STAN WELCH D483/ FELONY/ ST@ @ County of Santa Clarawaa ee wow il 12 13 14 1s 16 17 18 1g 20 21 22 23 24 25 26 27 28 Agormey atLew F ILE D Attomey at. Ten Almaden Boulevard suite150 DEC 2.9 2014 San Jose, California 95113 (408) 280-6600 State Bar No. 119398 Attorney for Defendant ‘XIAN OUYANG SUPERIOR COURT OF THE STATE OF CALIFORNIA FOR THE COUNTY OF SANTA CLARA. PEOPLE OF THE STATE OF CASE NO. B1476048 CALIFORNIA, ORDER FOR CONFIDENTIAL Plaintiff, APPOINTMENT OF MENTAL HEALTH EXPERT PURSUANT TO } EVIDENCE CODE SECTIONS 730 vs. AND 1017 XIANGYU OUYANG, Defendant. iT I$ HEREBY ORDERED that pursuant to Evidence Code Sections 730 and 1017: is appointed to examine such evidence in this case as is necessary; to prepare a confidential report for defense counsel, giving the results of said examination to defense counsel, to consult with defense counsel regarding the defense of the above-entitled case and to testify on behalf of the defendant as an expert, The costs and expenses of such examination, advice and testimony, are not to exceed $ without further order of court, will be paid by the County of Santa Clara, California, on certification of such costs and expenses by this court, Dated: 2 /ashev Lhe Bi1. | ADRIENNE DELL ‘Attomey at Law 2 | Ten Be Boulevard Califia 95113 area 28 fae Bat No. 118358 5 | Attomey for Defendant KIANGYU OUYANG SUPERIOR COURT OF THE STATE OF CALIFORNIA FOR THE COUNTY OF SANTA CLARA PEOPLE OF THE STATE OF CASE NO. B1476048 10 | CALIFORNIA, REQUEST FOR CONFIDENTIAL at Plaintiff, APPOINTMENT OF MENTAL . HEALAH EXPERT PURSUANT TO 12 EVIDENCE CODE SECTIONS 730 3 vs AND 1017 1 XIANGYU OUYANG, \ 14 Defendant. 15 ) 16 | TO THE HONORABLE VINCENT J. CHIARELLO: a7 ‘The Defendant, XLANGYU OUYANG, submits the following points and authorities in 18 | support of her request for an order appointing a mental health expert: 19 I 20 ‘THE RIGHT TO COUNSEL GUARANTEED BY BOTH THE a1 FEDERAL AND STATE CONSTITUTIONS REQUIRES THE 22 APPOINTMENT OF NECESSARY EXPERTS TO ASSIST IN 23 PREPARATION OF A DEFENSE. 24 28 Tt cannot be doubied that the right to counsel guaranteed by both the federal and state 26 | Constitutions includes, and indeed presumes, the right to effective assistance of counsel, and “the 27 | right to effective counsel also includes the right to ancillary services necessary in the preparation 8 | ofa defense.” Keenan v. Superior Court 31 Cal. 3d 424, 428. (1982). 4 xean ee UY de Ww 12 13 14 as 16 ay 18 19 20 21 22 23 24 2s 26 27 28 a ‘THE RIGHT TO SUCH COURT -APPOINTED EXPERTS IS SUPPORTED BY STATUTE Evidence Code Section 730 explicitly provides for court appointed expert witnesses: ‘When it appears to the court, at any time before or during the trial of an action, that expert evidence is or may be required by the court or by any ‘to the action, the court on it own motion or on motion of any party, Inay appoint one or more experts to investigate, to render a ‘as may be or the court, and to testify as an expert at the trial of the action relative to a fact or matter as to Which such expert evidence is of may be required. cis UPON A PROPER SHOWING, THE DEFENDANT iS CONSTITUTIONALLY ENTITLED TO ACCESS TO EXPERT PSYCHIATRIC ASSISTANCE, A defendant must be provided with access to psychiatric assistance at trial, when the defendant has demonstrated that his mental state at the time of the offense is likely to be a significant factor in determining guilt. As the Supreme Court state in Ake v. Oklahoma, 740 U.S. 68 (1985), “When the defendant is able to make an ex parte threshold showing to the trial court that his sanity is likely to be a significant factor in his defense, the need for the assistance of a psychiatrist is readily apparent, . In such a circumstance ..._ where the interests of the individual and the State in an accurate proceedings are substantial, the State’s interest in its fise must yield.”DECLARATION IN SUPPORT OF REQUEST FOR APPOINTMENT 1, ADRIENNE DELL Deciare: 1. Taman aftomey licensed to practice law in the state of California and am representing XIANGYU OUYANG, the defendant in this action, 2. Ms. Ouyang is charged with four counts of poisoning, in violation of Penal Code Section 347(a). It is alleged that she poisoned drinking water belonging te classmates in her graduate studies lab at Stanford University. esa ee wn Pe ai 12 3. My knowledge of this case indicates that my client may be NOT GUILTY BY REASON OF INSANITY with regard to the instant charges. Prior to entry of such a plea, J would like a confidential examination of my client by a mental health expert. 13 14 7° 1 am requesting that this court appoint such a expert in assist me in the evaluation of my 7 clients mental state at the time these offenses occurred. 1 swear under penalty of perjury tha the foregoing is rue and correc. 20 21 || Dated: a2 23 24 25 26 27 285 | Attorney for Defendant XIANGYU OUYANG SUPERIOR COURT OF THE STATE OF CALIFORNIA FOR THE COUNTY OF SANTA CLARA PEOPLE OF THE STATE OF CASE NO, B1476048 CALIFORNIA, REQUEST FOR CONFIDENTIAL ii Plaintiff, AP} OF MENTAL, HEALTH EXPERT PURSUANT TO 12 EVIDENCE CODE SECTIONS 730 vs. } AND 10! 13 - XIANGYU OUYANG, Defendant. 15 ‘TO THE HONORABLE VINCENT J, CHIARELLO: ‘The Defendant, XIANGYU OUYANG, submits the following points and authorities in support of her request for an order appointing a mental health expert: I ‘THE RIGHT TO COUNSEL GUARANTEED BY BOTH THE FEDERAL AND STATE CONSTITUTIONS REQUIRES THE ‘APPOINTMENT OF NECESSARY EXPERTS TO ASSIST IN PREPARATION OF A DEFENSE. It cannot be doubted that the right to counsel guaranteed by both the federal and state Constitutions includes, and indeed presumes, the right to effective assistance of counsel, and “the right to effective counsel also includes the right to ancillary services necessary in the preparation ofa defense.” Keenan v. Superior Court 31 Cal, 34 424, 428. (1982). iee 20 LL 12 13 14 15 16 ay 18 19 20 21 22 23 24 25 26 27 28 a THE RIGHT TO SUCH COURT -APPOINTED EXPERTS IS SUPPORTED BY STATUTE Evidence Code Section 730 explicitly provides for court appointed expert witnesses: ‘When it appears to the court, at any time before or during the trial of an action, that expert evidence is or may be required by the court or by any party fo the action, the court on it own motion or on motion of any party, may appoint one oF more experts to investigate, to render a report as may ‘be ordered by the court, and to testify as an expert at the tial of the action relative to a fact oF matter as to which such expert evidence is or may be requised, m UPON A PROPER SHOWING, THE DEFENDANT 1S CONSTITUTIONALLY ENTITLED TO ACCESS TO EXPERT PSYCHIATRIC ASSISTANCE, ‘A defendant must be provided with access to psychiatric assistance at trial, when the defendant has demonstrated that his mental state at the time of the offense is likely to be a significant factor in determining guilt. As the Supreme Court state in Ake v, Oklahoma, 740 U.S. 68 (1985), “When the defendant is able to make an ex parte threshold showing to the trial court that his sanity is likely to be a significant factor in his defense, the need for the assistance of a psychiatrist is readily apparent. . In such acircumstance ... where the interests of the individual and the State in an accurate proceedings are substantial, the State’s interest in its fise rust yield.”ano ews in 12 13 14 a5 16 a7 18 19 20 21 22 23 24 28 26 27 28 DECLARATION IN SUPPORT OF REQUEST FOR APPOINTMENT 1, ADRIENNE DELL Declare: 1. Tam an attomey licensed to practice law in the state of California and am representing XIANGYU OUYANG, the defendant in this action. 2, _Ms. Ouyang is charged with four counts of poisoning, in violation of Penal Code Section 347{a). It is alleged that she poisoned drinking water belonging to classmates in her graduate studies lab at Stanford University. 3, My knowledge of this case indicates that my client may be NOT GUILTY BY REASON OF INSANITY with regard to tbe instant charges, Prior to entry of such a plea, I would like a confidential examination of my client by a mental health expert. 4, Tam requesting that this court appoint such a expert in assist me in the evaluation of my clients mental state at the time these offenses occurred. 1 swear under penalty of perjury that the foregoing is true and correct.1 PALO ALTO COURT CASE NO, Bi476040 270 GRANT AVENUE | "Cr CEN 14054550, PALO ALTO, CA 943Q, AZ/OL, 314 9106 AMEPT. 85, SPLEVS. XIANGYU GUYANG TNL 11/02/1988 DY BKrY A 601 CLEMENT WEST ST el =FK Le CRUZ EDELS F SINGAPORE, 12060: HEARING ARRAIGNMENT GE HON. VINCENT J. CHIARELLO DV; AGENCY ST-STANF-KEB64-KIM PORTER CHARLEY BAGATELOS CHILD: STATUS: O-BER -50000 ™w FATTY. DA JAMES SIBLEY APO ARGES (O01) PCBA7IAD F (002) P0347 (A) VIOLATION DATE 09/01/2014 Peoos REST A) "aaa sex aPeennane an. DES Zideterniant Prosept Ti Not Present Snes gaa Zar Wav C} Amand Comes Pica (IOC CIPTC [}Preb/Sent Ci itorreter 3)P087? C Filed (4n Fle [1 ep. Adv / Wav G] BalfOFY SORP Rect Dr Apt [J FARV ERC [Bai Apply Balance Exoneeted SING Ci€nteredby CRT CINGBRI/ Ady C]PSol C]Freiim C]Reatiness C35/BMTC [Ball Exonercied []Fortlted Bond #_—___ ies Por! Alegatoa/ EnnanoementsRotvcal C] Furher C2.ury C107 C]Pe0/De Wav Juy Cj Reassumplon Fied [] Foroture Set Asie) ail Ren rw CJTNW CTW /WO CTW Sentence) Cis_____. Costs Within 30 Days to Cou i et/ Apt PD /ADO/ID0 [] CandDeeiZ] Adm AIF CAPO /DADE/Prop86 []PO6 ReAscat: — SORP/OR [] Revoked [} Reinslaied [1 May Post & Fret 1 BD 1100 Special App. Sworn 5 Clean Proc Susp [2 fain FE) Sata Hey (BW ordered §______'[ siayad [To issu S)ihtg on Motion Doubt Dect Pursuant °C 1268, [EJNo Gite FeteaserSOr [] No Request [] Cash Only AGranted [Denied [Submited OW Cal [}S.tmon Report [Found —.._________. BW Set Aside [] Recalled [Fld C) Remain Out Cj NW 2] Stip 1 Comm (3 Drs. Appointed (CiMe« Term (commited Poot of Pro Wev (1 Cartied fo General Jusscbon (MOA, COM Ameed io J] Amended to [1] {M) ¥C12500(2) / VO2310a(a) [Pur ¥C23103.5 [1] DA Sint Filed PLEA Conditions: [J None []No Stale Prison C]PCT7 after 1 Yr Prob [ncldes VOP “Hall PisonTorm of EE had Cal) Vacate ponding dato olemisal/ Sng i i a Sant Cy HUG D 5] Ai Max Pon Partai 7 Appel) og HS TTSGORCRSOPCAST TPO 0 [IFSP Einav ¢) POzsenneoe0s0scceeBN/o e078 Wav Right to [] Counsel [j Court / Jury Trial [] Subpoena / Confront / Examine Witnesses [) Settincrimination [3 Written Waiver fled [Plea / Absentia flog 5}COP JGUILTY [NOLO CONTENDERE to cargos & admis ashancomentsatopatons/proxs []PGYT (] Abuckle (Fatal Basis fond) Fdngs stated 2 Prop 36 Granted / Unamenable / Relused / Term €}DEJ Elblty Fled (} DEJ Granted /Flin/ Term Fee $C] Gully Plea Fondored Waives Referrat C]APO Full Rpt C)CR110 issued Fines/Fees Pay to: 088 DTrafic C)Cout [Today C)Audlt Sent Suspended __________--______. TJ PROBATION DENIED = COUNT___$__ + PA$_["] Purs HS112500 PROBATION [Execution [Jimposiion ol sentence suspended for probation porod COUNT $+ PAS] Pc2008 SICOURT C]FORMAL PROBATION GRANTED for.-.._Days/Mos Yrs AIDS/ GPP $___—- + PAS SORP. <] Report to APO within. Days () Terminated [1] Upon Relea: ‘OPF $+ PA S_______EMAT §. 2]Periorm Hrs Volinier Work as directed PO/SAP CJinteuol fel = LAB $s PRS Snot crive wo valksDL Bins (]Adv VC29600 OJHTO C]Reveter —-DAF/AF — $___ AdgIRF'S__Susp'd Potz0z.aqia JMOP C)FOP () 12hs (3 mos 9mos Enroll within ____ days AEF $____ Original Fine $. 5 DL Susp? Restrd/ vd for__. (ID NovOrdered/ Rmv'd Term ____ Yrs SECA/COPA §. CTS PC2900.5 $ =] No contact nith victim oF family /co-detts unless appr by APO ("| PC1202.05 ICM s TOTALDUE 5. =| DVPO issued / mod /term'd Exp_________ [Victim Present iCIN s Payments Granted / Modified No Contact {"] Peacatul Contact E]DSA thru APO/DOR/CRT CL] Filed AR $__ $___J Mo beginning, 4 yet pumipossess canchy weapons ‘( Destroyfret weapon SHELTER $________ FINE STAYED. YAW HO OV $0 committed @ § ——Taay Tay Pay Out = Submit Search/Testing []EGuc/Voe TingtEimpl [-]No alcohol drugs or where 80d ary = Consseftone to iy EMay Pay =] Substance Abuse, Psych, Theli, Anger Mgmt, DV, Parenting cnst/ prgm ASFS25CPFS10$____ Fine / Fees [j Deemed Satislied [} Commuted =| Pc2a6 (DNA) [] PC1262.1 HIV Test / Eduoation PINVEST §. OPSUP Ss ‘Mo CWaived Wor: Ewa Claire ChAcnt/Oenies Vos [J Court Finds VOP/No VOP Gar 129-75)905050 © Tjadati Fass Want Prob Fein / Mod / Ternid/ Revoked / Remains Revoked / Ext 0... SECA OM. FEN, CAA, PNVEST. PAUP SEES NOT CONG OF PROB J Orga Toms & condone Except as Arend Rae Grecticycen § to {FeME*® Fits cctorinod by APOGout CiRaoredie WAC Cole Cy ICDCRParele colette rom DeFs earings [] Blended Sentence County Jail Prison Torm J ¥rs Enhancement / Prior Yrs/ Styd /Stikn HAS / DAYS / MOS ISON C) Seb Attactt Count FM Violation Enhancement, WisiS Enhancement’ VrsiS ~ Enhancement Vis Enhancement YrsiS Enhancement YisiS Total ] Hae ACT. Eyaoie Che Os Cypcaes Feat Total tm ‘GbOR FE 1708 5] Swaight tine C)in Camp S]WWP [)PC1209 Fees [7] Waived [) Cour Rec____All/Excopt [1] EMP/PSPYERP/DAPICo ParoloNP_—— {C1Sent Deemed Srv C} Ft Parcel win .__L] AowORD —___ Yrsios ParceAS/PRCSTAppeal £] Consec [ Cone to, “Bal C) Susp [JAN but _—_Hre/Daysilos }On Cond Complete Posidenial Treatment Prom [}Serve Consec MOTUWENTHFRISAISU a 'AMUPHA or Soonee REMANDED BAR ‘TIAEMAN AS SeT C]NO BAL | GONBATTED eae [IAG PRONE ASST []PS5) {C1AS COND OF SORP_[JBAIL NGREASED/ REDUCED [3 0 PRAMAS REC BY JAC NAVA BEDles peta alta court CASE NO. Bi4ye04e 270 GRANT AVENUE ver CEN 14054559 PALO ALTO, GA Fado. OATE 42/29, 214 9400 ANEPT. 8S OPES. XTANGYU QUYANG 11/02/1988 epy BKrY A 601 CLEMENT WEST ST 9607 CLERK Je MILLARD EDEL? F SINGAPORE, 12040 HEARING = PLEA 26E HUN, VINGENT J. CHIARELLO DVr AGENCY = ST-STANF-KS8446~KiM SORTER C. EAGATELOS CHILD: STATUS O-BB -50000 ™m oy SATTY.OELL, ADRIENNE (G) DAJ, SIBLEY ‘APO ARGES = F (QOL )PEB47 (A) (O02) PE347(A) VIDLATION DATE F (003) PC847(A) F (004) POB47 (A) 09/01/2014 B-18-15 GAM DES 1 APPEARANCE (Detendant Present C]Not Prasent nity Pr AR 20100 Spiel Ape Svaird C) Adv [lam Wav C] Amend Compinio’©) Arr 7 Pea [}i0G [PYG [Prob/ Sent (J interpreter Sworn 5 PCS77 £2 Fed (1On File Cj Rept. Adv / Way [) Bal ORY SOAP [1] Rect Dr Apt []PARY ERC [2] Ball Apply Lj Balance Exonerated SING [) Emoted by CRT CJNGARI/Ag” —E]PSet Prelim [) Roadinoss C)S/BNTC [Bal Exonerated (Forteted — Bond ¢—____ 5 eries Pots Allegations! Entancamérs(Ratusal[- Furher [3 Jury CICYT [Poo Del Wav Jury Cj Reessumton Filed () Fosteture Set Aside [Bal Raln Sprw CLTNW COOTW/WD CTTW Sentence CReft Cis_______ Cet within 30 Days to Court = Ref Appl 90 ADO 00 [) Can DeclC] Am A/F [JAPO/DADS/Prop 36 F]PS8ABAGETA SORP/OR [Revoked [_ Peinsiated [7 May Post & Forti B——_Freloves_— appt 1G Proc Susp (Rein Stats Hg TI8W Ordered} Siayad C3 To iosue Big an eon [F) Doubt Deel Pursuant PC 1368 E]No Ce ReteasaiSCrT [] No Request [) Cash Oniy ‘DiGranted [}Doniad [) Submited [JOH Cab ©) Subm on Report (-|Found _ BW Sot Aside C)Recaled [Fed [1 Remain Out CNW [BStip to Comm 1 Ors, Appolnied: Gltax Tern [Dicom Ej Prot ot Prelim Wav [) Certed to General durecition (DA / CON Amended to [Ey Amended to E3(M) Vo12500(a)/ VOR3t03(@) F] Pur VC28103.5 L] DA Simi Fed. PLEA Conditions: [} None []No Slate Prison [] PC17 after 1 Yr Prob} Includes VOP- {Cdl Prison Term of [Aad to Cal) Vacate pending dato [GQ DiomsalStiking ry scbmtme of Sent Harvey Stp lady Max Pen / Parle / Prob mmig/ Appeal [) ag HS¥7580°PC200/°287./PC180.20 [FSF] FresiFees (-]Pczeaco/20g0s"30ensisan/VC1e07.8 ‘Wav Rit to [) Counsel [J Gourt/ Jury Ti €} Subpoena’ Contront/ Examine Wiinesses [] Selnernination [writen Weiver tied [Plea Absonia fied [SCOP [)GUILTY [}] NOLO CONTENDERE to charges & adrits enhancements allegations priors ()PC17 [1 Auete [] Factsl Basis ound [Findings stated El Prop 36 Granted / Unamenable / Refused / Term [) DEJ Ekglbillty Filed [J DEJ Granted /Rein/ Tenn Fee $____[} Guilly Plea Randered ElWaives Relerral (JAPO Fullpt C]CAI10 issued” FinesiFees Pay to: (JDOR [Taio (jCout [jToday CjAvdt Gisent Suspendoa. LJPROBATION DENIED COUNT._.§___+ PA$____[) Purs HS1 13500, BROBATION [- Execution Jimpositon of sentonon susponded for probation pevod COUNT___$..___+ PAS§__ [1 Pc290.3, (OCOURT [)FORMAL PROBATION GRANTED for___Days/Mos/Yis AIDS /CPP $+ PAS __ SOAP. ‘Report to APO within. Days []Terminated [} Upon Release DPF g «Pas. EMAT § EpPeriorm___Hrs Volunteer Work as directed PO/ SAP [Tin lieu of fnatJail LAB S___ + PAS. GNot drive wio valid DL. & Ins C] Adv VC23500 []HTO. [ Re-refer DAFF © §____ Add AF §. ‘Susp'd PC1202.44/4 GMor FOP 12h ()3mos O8mos Enroll within days AEF $__— Original Fine §. ‘CIDE Susp Resiral Rvkd tor ENO Novordered/ Rmv’d Term _—___ Yrs SECACDPA §____ CTS PC2900.5 CINo contact with victim of farnify /co-detts unless appr by APO []PC120205 ICMF = $____TDTALDUE—§ E)DVPO issued / mod Aern’d Exp —______ [Victim Present ICN $____ Payments Granted Modified EJNo Contact [j Peaceful Contact []DSA thu APO/DOR7CRT [jFiled AR $___ $__/ Meo beginning. Not ownipossess doadly weapons L}Destroyretum weapon. SHELTER §___ FINE STAYED Stay away from. bv ‘ ‘Commited @ $___/day CiMay Pay Dut ‘DSubeit SearcsvTesting []EduaiVoe Tigikmpl CJNo alcohol arugsorwhere sod ATTY Conseeicone to. Substance Abuse, Psych, Thett, Anger Mgmt, DV, Parenting ons! / pgm —_ASFRZSICRFSID§. Fre Foes [] Deoned Salsod (Commas 1PC206 (ONA) [} PC1202.1 HIV Test/ Education PANVEST § CoPSuPs nto (Waived VOP:(] Wav C]AR'd_—___ ]Amts‘Denies Viol [}Court Finds VOP /NoVOP Gar $129,758250.50 §. Ty Asati Fees Waves Prob Roin/ Mod / Ter'd / Revoked / Remains Revoked /Extto________[ SECA, OM ICIN,CJAF, PIVEST, PSUP FEES NOT COND, OF PROS 1 Orginal Terms & Conditions Except as Amended herein Rest C3 Gon ° nous wie )No $0 cua Geeceminan TIN Fuuthor Peres /Raviows > A oserind by Tavera wie [3catoa aly JAILJPRISDN [See Attachm't Pp (]CDGR/Parote coiect rest trom Dots earings LBtended Sentence County Jait ‘Count _FIM Violation Prison Term / Yes Enhancement / Priors Yrs 1 Siyd /Stikn_ HAS / DAYS / MOS (et es Enhancement iss Enhancement Ass) Examen Yes, Boone se za crs. ACT 4. woe oe Ole Cypcees1 Total Total tem (CDCR IPC 1170n [Straght ime CJIn Camp CJWWP [3 PC1209 Fees [J Walved [Court Rec___Al!/ Except €) EMP/PSPIERPIDAP/Co Parole/NP___ [C)Sert Deemed Sn [) Ape to ParolelPrab win] AdvORD ___.__ Yrs/Mios ParcisMSPRCSAppeal [) Consee ) Cone to, (C)Bal CJ Susp }Al but ___Hre/Days?Mos (} Dn Cond Complete Residenial Treatment Pigin {] Serve Consee MOTUWETHFRISASU, ©) Preprocess______ AM/PM [1] Stay / Surtender ? Transport to_______________.@. ‘AMIPM or Sooner [EV REWANDED BAL § CJ REWAN AS SET CINOBAIL [JOOMMITTED [RELEASED (JOR (]SOMP —[]IAC PHONE ASSNT]PSS IAS COND OF SOAP _[JBAIL INCREASED / REDUCED _[] TO PRGMAS REC BY JAC DOC TO ARRANGE TRANSPORT UPON AVAIL BEDi 6 case no, BIAT6048 wu €o5_ CEN LOOSS550 eR DATE OB/1BEO1S F100 AMEPT. SS PLE VS. CLAN Livoe igee CbY Bust A 601 CLEMENT WEB SP 0607 CLERK ae CRUZ ia SINGAPORE, L040 HeannG = LEA 368 dl YESDENT J. OHLORELLE UV AGENCY BT STARE —dhGob—nitn PORTER OY BAIA ELLOS Chilis STATUS teEB Satu ™ 5 ATTY, 4 a) OA JAMES BISLEY APO MAGES UL PL) F(OOR) CRA? AD VICLATION DATE > Gi /BGi4 wrmmannce 2 2071S am 08'S /oetendace Present [) Not Prosent oy orem CRATE HOSS Aird [] Adv C] Ar Wav (3 Amend Compfinto (Jr (7/Piea [IDC C] PTC (Arab /Sent 4/7 Inecpeoter Bee ee a oe Lea Ok Cri en Sam eames 3he aeienszem eon/tn Gi tn Cems OS/Aare Gieern t Stess i ternal Coy LCF ley re SRO OM On aay See a a Gio [OTR ent Sn6 7G Ee hes ny en ces eit Se cee aracameae See eae Poneanenre Si ae Joni oe sins DOG! Sent crors Dave 38h cern on ees Oe a Spent en earn UE PLEA Conditions: [None [)No State Prison [J PC17 after 1 Yr Prob (1 includes VOP. Jail / Prison Teen of [Add to Cal [] Vacate pending date Be ee ge PO See ati re oi OTERO IRD CTR te Crean eoe he, ee Ea gt Sr! ri em cr en hs rt Boer Dem Cha ovine ee eerie annoy Jame an bai Cee irc mes trent Rete! er Oe rns EL tesa er ena ga en nt ain od peas faves Coo ane Cie Cr Boer ce ROR Creat Oa Prosaton Cccaan isin forirenmmroninpeninars SOW —— Ak ee iD / PO 100 / Specs! ApP Tswom \leved_—_.__Apatd Steg on Motion E] Report to APO within. Days ()Teminated [jUpon Release DPF $+ PAS____ ear $. EiPeriorm____Hirs Volunteer Work as diécted PO / SAP jin eu of finallal = LAB §____ + PAs. 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[1 AdmitvDenis Visi) Coun Finds VOP/NoVOP Jar ¢129.75425050 § TC ]Adati Fess Wawed Prob Féin / Mod / Tenn / Revoked / Remains Revoked / Ext to. Ci Original Terms & Conditions Except as Amended herein TiCo-terminous witty] Ne Further Penaities / Raviews ther: CISECA, ICME, ICN, CLAF, PINVEST, PSUP FEES NOT CORD. OF PROB (Pest JGen $0, DAs dotomined by APO‘Cour [}Reened to WAC [)Colect City UAILIPRISON [} Seo Attachr't Py []COCA/Paole collec resi irom Det's earnings C} Slended Sentence County Jail Count _ FIM Viotation, Prison Term / Yrs Enfiancement Vist — Enhancement Enhancement / Priors Yais Enhancement Yess Yrs / Siyd / Sirkn_ HRS / DAYS / MOS Enhancement YrsiS Enhancement Yisi Total a ACTs 4019 1% CiPcasa3.41 {Di Sent Docmed Sra [] Rot to PerterPrab win. AdwoRD {Cia Gy Susp [7 Al but —_Hre/Days!Mos. [] On Cond Completa Residential Treatment Pram [_}Serve Gonsee MOFTUMVE/THIFASASU [Preprocess________. AM/PM_( Stay / Surrender / Transport to. TiREWANDEDAAILs—— | ]REWAIN AS SET (JNO AN [JCCAMATTED [RELEASED [JOR [SORP [JAG PHONE ASSHIT[]PS5 [LUASCOND OF SORE.” E]BAIL WCHEASED / REDUCED ~[] TO PAGNTAS REC BY JAC BOO TO ARRANGE TRANSPORT UPON AVAIL BED. CiStraight time [in Camp EIWWP [PC1209 Fees |] Waived }Cour Rec_____Al/ Except [] EMPIPSP/ERP/DAP/Co ParoleiNP.__ Total Total ter ObCa/PO T1705 ‘silos ParcleRtS/PROSIAppedt [1] Conser 1] Cone to. ‘AMIPM or SoonerDowntown Superior Court (DTS) - The Superior Court of California, County of Santa Cla, Page 1 of 2 ADA THE SUPERIOR COURT OF CALIFORNIA COUNTY OF SANTA CLARA DOWNTOWN SUPERIOR COURT (DTS) Location & Contsct Info Street & mailing address: 181 North First Street Sen Jose, CA $5113, Glick to see mag and get driving directions Phones/Contact information Main phone number: (408) 682-2100 Small Claims Advisor: ses the Small Claims Advisor web page fur contact information TDD: (408) 882-2800, and for Jury, (408) 882-2591 fior hearing-impaired use only) For courtroom numbers, see below. Also see Civil, Probate and Small Claims phone numbers on the ist ot main Cour Telephone Numbers. Types of cases heard: Cisil, Probate, end Small Claims Parking taformation: Ses the downtoan Sen Joge parking map for cates end public Parking options. (The lol adjacent i9 TS previously usse for parting is now Bnd gh al sega tes new Family Justice Center) Check the VPA lovin anc light all) and Caltrain websites for puble transportation options OTS Business Hours Alternative Dispute Resolution {ADR} Administrator: § am - Spm Clerk's Office: 830 am - Bt 3-00 pm * Calendar Unit: 8:15 am - ferme 3-00 PR? Probate: €:30 am. geaeme BOOP 5 4 9 oy ‘Small Claims Clerk's Offioa. 8:30 em - 26 wt Drop Box Information at DTS Zqhe DFS Drop Box iocated in the lobby and available to anyone seeking to file civt Hrongee Hs with the Clerk's Office. The lobby is open trom 8.00 am, to 200 Pam, Monday through Friday Click for guidelines on using tha drop bowCounty Administration Building 70 West Hedding St. San Jose Ca 95110 1* Floor, East Wing (408) 299-2481 Services Include: Birth Certificates Marriage License Marriage Ceremonies Death Certificates Process Service & Photocopier Registration Fictitious Business Posting Environmental Declaration Posting Oaths of Office Family Court Contact Information 170 Park Center Plaza ‘ San Jose CA 95113 (408) 534-5600 Divorce Records Restraining Orders | Superior Coust of California | County of Santa Clara / Website Addresses / Main Site: www scosuperiorcourt.org Self Service Site warw.seselfService.ore Complex Civil Litigation Site: ven secomplex.ore Public Case info Site woww-sceaseinfo.org ae SeeBepacenentst Sey ‘Office fhe Sherif Sania Clin. ovnty 71 Sera Set Sard CA. 9008 Phan: (30) T0833 Fs (6) 258185 INCIDENT REPORT. neon Te 347(a\1) PC [F] Poisoning 14-316-0081U . a ensita | Fri Locatowormcivent 337 Campus Drive / Stanford / 94305 / Lorry Lokey Stem 7° Aaa Mon Goll Research Reported | 4aintita Tue Case = om = = = {AT FRET. DDL RW, BLESS) Terao ea Lew P| oo ie eo asst VO iit fas] XING Liyjing wrenmrarecoen: Cieaucn C) verwwrse NOTA, VTIAADSED: [SEAL ASSAULT VINNT ASSIST |” _DONEETIO WOLENGE Clonee Ludan ‘Women ASST. |_| DOMESTIC Vi ENCE “meas ea te a = ira, | BUSINESS NAMEISCHOOL MAME AND ADERESS "CATVISTATE oO TRAGIC VicTIMINFORMATION: [[} NON DISCLOSURE (WHERE APPLICABLE} CJmsuey Cjsear Getooo CJurme [) protocraes: snoer o ae a FRORETTY GT FOR GvOENCN COMPLETE STOPS GF NGDENT This REPORT IS FOR INSU "URPOSES AND TO ALERT THE SHERIFFS OFFICE OF THE CRIME. mona: Students reported that finking water occasionally smells and tastes strange, (SJOUYANG has been” identified as the suspect. The criminal investigation continues. All precautions are being taken to ensure the health and safety of the students. de a Ase Baka Tapas T aswonacose ha rmesstngs opts [latent oy [Thonn semten eps Ard aa | [Jaconorran” tec [Aronrtetse thuawar = [Josarfoee”—[ipoacnrtomes’ nen LEBEL LaSTiSne Seats fecrarcscces Straps fates ornare =a Clemursweese — Gowrsiee™ arte tatevowgy [Putnam | oven stat = ie SS SS SS GS Sn Daman Sarma | Comte ave * Post armen” free fer ven [Ginnie Pasian | Cetin Pome ieertocemen Foe cme ie Potente tap Peta ae uence one foam et Ree Hires” coe feenamne foun (oct Orice Neston) | Get card Spoiog Goose P6totemny | ue {ise Si Rents Rontowe Hee | CaneyCaine—Toevcon Soop | teste x Senoot armah Eq Tote joer [pace ete se aad ete sana ‘sewer ‘Frans Trmstucitey Ein enim Hrarsches 2 anannoarange [ecccaa — Steaugcy”” [amature eoaretbn [fet feten so connie haat | OTHER ND INFORMATION — | ova | STRSTR Sa et ea — Se Same Sa SaTanaoe sian ~ BROT TOE ae emit peer | aa ate snendet chratopn ert Suzuie et] “TSawe rrrssonne om S| cues TF 44346.0081U a= vit w= neromG pay “aE i TST FAS, DOLE i NESS) TJarareorca [sate | fh 005 na Lt vos op == Ri ‘Youngseo TNTERPRETERIgPEDED: (SPANISH [2 VIETNAMESE [werararses. Ceeswa.assauct E]vewrassisr.. C] aowasre womce “oress corvaare BNESS MOISE | weruncomaron Civovocaosuie wneneareucnaie Cirumy C)ea) Cla (lume Cl rvarocrarn Genser | {AST FT AOE RU BUSHES) V04 JaROWN Kathoring Vernaowste [Sawa achat jvc asst Elson (AST ET, ODL OUST) VO5 mrzuTaNt mania Vemanste: Cibwa.asounr (Jwenwrasser [] powane woumce . noses arVaTarE 2 ran VON DISCLOSURE (AMEE APPLICABLA) (-] MaURY (-] SAAT |] ROOD “]pror } STENT TAS BRST, MOLE DAN, FUER fro [oe ffen ([Wonmmmse [CRewil assaul?[Jicnmrassit” CYooutene wanes crraTATE a = may CO] ear SAE Vemnorsti: [SeunLASsANCT [Ivewrasset [7] oat wouance aonress arene =a = |[PURNESS anerH0o. KANE AND ADDRESS cree vcrwwonmanion: {]NoworecxosuRe wwreeeaerueanie,” [Joaay [] aser Cjecoo Cure Cjenorconern i sneenr Kir, tke wer | tata sta) Cohendet, Christoph |2601t | 1H/21/44 9Rae Cara Tartare ie arate |B o%e Pern rasan S| irate et iar 14-316-0081U) Tl srawen C) vernanese, “oon wiciBice civarare ~ Sve ass? VICTMA INFORMATION CJNON DISCLOSURE (WHERE APPLICABLE: LJ iMmRY C} sar [Jeooo [jukae [Jesotocraee SrVsTATE “VICTeRINFORMATION. —_[_JMON TISGLOSURE quTIERE APPUCARO CE] many) sat Csioon Civane Cirnorocars: id] stews AST, ARST, DOLE (RM BUSINES a i ace ar 004 Jou Giovanni INTERPRETER NEEDED. (SPAMS) ETNANESE Viermovers: Crown assay Cveanrassict C) oowesre woven Vera Tone Poa vermaronuaron Enon onctosure wmencarucns Clu Cl ew Clacco Cjumne [jrvorooraes swans low [= — [ee t 2 7a = eer ‘exo oe oe Wane Bruce un’ fs “Elermcn ) venawese 7 Wemaonae CREAN AssALT ]wciwerasnisr [7] cowesn wouece I “Jere onsen ors ead NBER (ne ST (rue SUNESSTOORTSCHCOUNAME ND ODRESS——SCSCS*CYSTAE 2 FOE 0% Viermnontation [Jno o1soe sue ‘LAST, FIRST, MHODLE (FR, (F BUSINESS} ACE ls a 006 Joes Lary aieenereaaaeoen. J saeen CT WaThnarse [Metmrovee, Chowazssauut (lve sest.C oowesve vo.rnce i ever Ce ae Semen ‘vicTiMiNFORMATiON: — ]NON DISCLOSURE WMEREAPPLiCAsS) = {[Jmuuey [] sar ClaLcoo []uRN= [] PHOTOGRAPH ( stuenr Fee ST OE sarcan ao [PERS Ra SE TE cal mon eT rane e ST [ear Suen Ssesoat Vee [ sureten [staat University Dept of obi Safe 71} [F Polsoning cars Comty = ViCTINE TASC aT ROE RO O07 HSU Ken Tein ChowAAsanr Chewrest (7 sovernevanee 4 Snaae a even ae ion ea eee Temenronserio CINONDISCLOSURE WERE ArmueanLE) CJmuuRY C] seer [Joo Flume Crioroown Dsicenr “areca Bene aE TareAe a | BireRamORE RENEW —[owamaER [DE BE in ica reo | 1utane ssa] [connor Christoph 26011 | ftztia asi] 436seponr ree sur ind aly 2471019) PCF Plaoning ‘one 44-316-0081U tnt Pr, wok wR sce twa eb OUYANG Xiangyu Chines Fx 49/02/1988 = 26 2" 120° Black Brown Tans enone To eTa erenereeeHDED Shaves eT sone orvavare 2 Pe = 01 Clementi Wost Strot #0607 Singapore ‘2060 (656) 770.062 vanes etichon, oa SOORESE cinta pe PRONE oro 118 itn Cour #403 Stantrdce 4008 _(650) 404-3816 aww Bae 8 oe en orn our oer CI Unknown hansrae wine Fae on ‘Sonpuion, WaPo ‘SCARS, MARKS, TATTOOS ETC. BALDISHAVED —-X STRAIGHT. CLEANSHAVEN —MEDIUNE atk “WaN0S (FEET ese. “ fave women vinen scan parecueo = RevOLVER OU ‘YOGrTOUPEE GoaTER (POT BELLY GAT RE ADO. SEE NARRATIVE crestcur Comrie Sanya souaro coe aseate naan, ranenene Time eae ee cool "narod umsusshesosr rs roman Na Seems "ism Sut state {ENDER THE INFLUENCE ne STTTER CLOTHING: Wis ame power “OTHER: ‘Stmulant (Cocaine, Mathamphatamines, et HPs eno cxpnar fad ‘uce ‘Doressant (oto, ote x ousses lar GLOVES: ‘SLVER 1 WELL GROOMED Other: Sinavses ONT mu ODL See naerarve man orreans ie sonune one SSorKOHGOrF—steemvoRS MEVEW —DOMEER ATE act oF vim, ike aor nianasta Cohendet, Christoph 260" 1VzINGOS 53aepont Te ‘SUPPLEME ‘Ststord Univesity Dept af Pati Safer 347(0)9) PC (F] Poisoning 14-316-0081U L. {SeaRiN OF Gmina EVENT MNO Ra AST FREY BOE EN NSD BTN 387 Campus Drive / Stanford / $4306 / Lorry Lokey Stem Coll Research ive ‘Uujng 1 2 3 4 5 6 7 8 9 20 a. 12 13 14 15 16 a7 18 19 20 22 22 23 24 25 26 27 28 23 30 LISTED INFORMATION ATTACHMENTS Copy of Evidence Sheet (s) Copy of the map of the first floor and second floor of Lorry Lokey Copy of Laboratory report (BC Laboratories, Inc.) that shows paraformaldehyde in two water bottles Copy of World Health Organization guidelines on Formaldehyde in drinking water Copy of Material Safety Data Sheet Copy of (V-2)ZHAO's written statement Copy of email from (V-1)XING expressing her concerns Copy of photos taken from the surveillance video in the first floor sw Stair well Copy of documents prepared by (V-3)RIM detailing experiments she ran NARRATIVE Oa Tuesday 11/11/14, at about 1010 hours, Sgt. HOM assigned me to accompany him to the Lorry Lokey building to assist with an investigation. While enroute, Sgt. HOM told me that we had been informed of a series of incidents at one of the labs that could possibly amount to a poisoning case. We arrived at the Lorry Lokey building located at 337 Campus Drive at about 1025 hours. We went up to the Nusse Lab (Stem Cell Research) located in room G2145 on the second floor. We were informed that (R)WAXMAN from the Medical School, (0-6)GIBBS from Environmental Health and Safety, and Lauren SCHOENTHALER from the Stanford University General Counsel office were on their way to speak to the students in the lab. At about 1040 hours, they arrived orrcaRsnime Dxwane DAE SRETDRS OFF ——_—SuPRRUISORS RIVE OMAR DATE pace oF in, Mike oir anaiaate Cohendet, Christoph 26011 1N2H/I4951 6 oe37a PCF Poisoning Supmens «Smarr en Ses arn eee 14-316-0081U SARRMTINE, DERN OF OREHAL EET BON ‘Vict Nae AST FAST MODLE FR PAIGE OTTUBS 337 Campus Drive / Stanford /94305/ Lorry Lokey Stem Coll Research ins Lying 1 at the laboratory. They spoke to the students regarding administrative steps. During that conversation, (V-1)XING mentioned 3 that she had kept the water that was in her metal water bottle from v the last incident on Monday 11/10/14. (That incident will be explained further in (V-1)KING's statement). In order to assist in establishing probable cause that a crime had e@ aan occurred and to quickly inform the victims if any contaminant were 9 present in their water bottles, a small sample from each suspected 10 bottle was removed and provided to (0-6)GIBBS. The samples were 11 tested by BC Laboratories. A copy of the sample results is attached. 12 a3 24 At about 1100 hours, (V-1)XING unlocked the third drawer at her desk 15 and pointed out the water bottle. 1 put on gloves before handling 16 the bottle. I poured a small amount of the liquid into a glass 17 bottle for (0-6)GIBBS. He secured the bottle for the purpose of 18 receiving quicker results of the contents of the water so that proper 19 health safety steps can be taken with all of the victims. T placed 20 the water bottle inte a paper bag for evidence. 1 also, collected a 21 metal mug that (V-1)XING had left on her desk that previously had 22 tainted water. The mug was placed into a brown paper bag for 23 evidence. 24 25 After I collected the water bottle and mug from (V-1)XING's desk, T 26 was approached by (V-5)MIZUTANI. She asked me to collect her water 27 bottle that she left on her desk over the weekend. She stated that 28 she did not smell the contents but was very worried about the 29 possibility of her water having been tainted also. I poured a small 30 amount of the water into a glass vial for (0-S)GIBBS and gave it to ‘OFFERS HAS pms are SHEtORSOFF —“SUPERVISOHSREWEW —JONUMIBER DATE vce or Kirn, ike 26017 Ttiztaate Cohendet, Christoph 26011 THRN4981 73aRemon ree supPLEMe {4T(aXs) PC IF] Poisoning (SOANON OF MEHL ENE EMO VIM NaN AST | ~ 14-316-0081U MOTTE TIEN BITES) RETO 337 Campus Drive ( Stanford / 94305 /Lotry Lokey Stem Cell Research aye, 1" 28 29 30 him. I collected her blue plastic water bottle and placed it into a brown paper bag for evidence. I went back to (V-1)XING and got her statement. STATEMENT OF (V-1)XING (V-1)XING is a graduate student at Stanford University and has worked in the Nusse Lab for about three years. The Nusse lab is located on the second floor of the Lorry Lokey building. (V-1) XING stated that the first incident occurred either in late August or early September. She went to the lab at about 2200 hours and her water bottle was on her desk. she often left out hex water bottle so she didn't think anything of it. she noticed that the water bottle contained a small amount of water, of what she thought was water, and drank it. She experienced an immediate burning sensation in her throat and mouth. She also noticed that the water in the bottle smelled like paraformaldehyde (PFA), which is readily available in the lab. she rinsed out her mouth and water bottle at the water fountain. She had no idea what could have caused the water to have gone bad. She never even imagined tbat someone could have put a substance into her water. After that first incident, she began smelling her water bottle before drinking it. Her water bottle smelled like PFA about four times a week for the last two to three months. She stili did not suspect that anyone had tampered with her water bottle. she eventually threw the water bottle into the garbage can. The day she threw away the water bottle, (S)OUYANG mentioned that she prcers we ‘orensen ate [SSIFTORYS ORF «SUPERVISORS REVEW —TDNUUHER ATE pace oF Kirn, Mike 26017 Tinartanta Cohendet, Christoph 26011 t1RttA951 Bgpom TP ‘SUPPLEME, 347(a)1} PC [F] Poisoning {pEATION OF ORG, EVENT IF CAIN VETMIRAWETLAST Fat ioe FP TONESND BoB 387 Carapus Drive / Stanford / 94905 Lorry Lokey Stem Cell Research ive, L 2 3 4 8 6 7 8 3 10 a 12 a3 4 15 16 aT 18 ag 20 a1 22 23 24 25 26 27 28 23 30 rnceRs ME romames OTe SMIMIDAYEOFF SUPERVISORS REVIEW DMUMBER OAIE pace Kim, Mike wor Tnznaste Cohendet, Cnristoph 26011 T2451 8 "Sane aierig Depo Pac Safer ‘Otic a the Soe, Sant Cara Cem NARRATIVE 14-316-0081U Lying noticed (V-1)XING had thrown away her water bottle. (8) OUYANG asked (v-1)XING why she had thrown away the water bottle. At the time, (v-1) XING thought it was a little odd that (8)OUYANG would ask ber about the water bottle being thrown away, but still did not suspect (S) OUYANG of having tampered with it. Another incident occurred when (V-1)XING came back to the lab to find only (S)OUYANG in the lab. (V-1)XING smelled the water in her water bottle and noticed that the water had gone bad. There was a chemical like smell coming from the bottle. she threw away the water and xinsed out the bottle. She still didn't suspect (8) OUYANG of having tampered with her water. She cannot remember when this incident occurred. The most recent incident occurred on Monday 11/10/14. (V-1)XING left on Wednesday 11/5/14 to attend a friend's wedding and was gone for the entire weekend. She had left her water bottle on her desk while she was gone. She returned to the lab on Monday 11/10/14 at about 1100 hours and like usual, smelled the water. A very strong odor of what she suspected was PFA emanated from the water bottle. She gave the water bottle to (V-2)ZHAO and she confirmed the odor as smelling like PFA. {V-4) BROWN and (0-3)LOGAN also confirmed the smell as smelling like PFA. (0-3)LOGAN handled (V-1)XING's water bottle when she smelled the contents. (V-4)BROWN did not handle the water bottle. (V-1)XING's water bottle was located on the front right corner of her desk on Monday. She does not remember where she left the water bottle when she left on the previous Wednesday. oF 4senor ve SUPPLEM MTFaK) PC [F] Poisoning TOeATON GF oman, EvENT IF COHEN “WCTIANONE {OST FRET WDOLE FP ETSTNESD 1387 Campus Drive / Stanford ! 94305 / Lorry Lokay Stern Celt Research sing, ey anak eee 20 a 22 13 14 18 16 a7 28 19 20 2. 22 23 24 25 26 27 28 29 30 Liujing {v-1)XING poured a sample of the tainted water into a glass vial and locked both the water bottle and the vial in the bottom drawer of her desk after pouring, She wanted to preserve a sample of the water for herself. (V-1)MING is very distraught at the fact that she does not know what she ingested, She suspects that PFA was the chemical placed in her water. She works with PFA and is familiar with the odor. (V-1)XING and (V-2)ZHAO went to Vaden Health Center and had their blood drawn for testing to check for abnormalities. {V-1) XING knows that (S) OUYANG is suspected of tampering with (v-3)RIM's stem cells. In her mind, (S)OUYANG is also a suspect in the tainting of her drinking water, (V-1) XING states that she had no problems interacting with (S)OUYANG on a professional level but never had any desire to spend time with her outside of the lab. There was never any animosity towards or from (8) OUYANG. NARRATIVE CONT'D It was later determined by BC Laboratories that (V-1)XING's water bottle contained 840 ppm of Formaldehyde. Det. FLOBRCHINGER assisted me by getting elimination prints from (V-1) MING, (V-2)ZHAO, and (0-3)LOGAN. ‘They all handled (V-1)XING's water bottle on Monday 11/10/14. He also got elimination prints from (V-5)MIZUTANT. orces Name naan nate SITOAYE OFF SUPERVSORE REVIEW —SDMUABER DATE pace oF Kir, Mike mor TZa ote Cohendet, Christoph 26011 11/204951 108gevo pe ‘SUPPLERE Dept a Pa Stes ‘347/a) 8) PC [F] Poisoning (Offi ofthe Sher. Sania Cara Coats NARRATION {DEATONGF ORGRAL VENTE RNOV VEIN ALT FRGT WOE EON F BUSHEY DOSS 387 Campus Drive / Stanford / 84306 / Lorry Lokey Stem Cell Research yng ees 14-316-0081U After speaking with (V-1)XING, I spoke with (V-2) ZHAO. STATEMENT OF (V-2)ZHAO (V-2)2HAO is a graduate student at Stanford University and has been in with (V-1)XING, just over by one desk. z 2 3 4 5 the Nusse Lab for about three years. Her desk is nearly back to back 6 7 8 (V-2)ZHAO informed me that her first incident occurred about four to 9 six weeks ago. Her water bottle was left out over night on her desk 10 in the lab. She drank some water from the bottle and felt a burning 12 sensation in her throat. She began to salivate uncontrollably and 42 felt her esophagus contracting. The water smelled faintly of PFA. 13 (V-1)XING was present during this incident and mentioned that the 14 same thing had happened to her before. (V-2) ZHAO washed out the 15 water bottle used continued to use it with fresh water. 16 17 (v-2)HAO never suspected that someone had tampered with her water. 18 Due to the incident, she started to smell her water before drinking. 19 She smelled the tainted water at least one or two times a week, 20 especially if she left her water bottle out over the weekend. 21 22 (V-2)ZHAO's most recent incident occurred on Thursday 11/6/14 at about 231700 to 1730 hours. She completely forgot to smell tbe water in her 24 bottle and took a big swig of water. She immediately experienced a 25 burning sensation in her mouth and throat. Her eyes became irritated 26 and watery. She began salivating uncontrollably. Tbe experience was 27 ten times worse than the first time. Her throat was burning so bad 28 that she could not even swallow the water. she went to the sink and 29 spit out the water. She rinsed out her moutb and drank some fresh 30 water. Tbe water had a really strong PFA like odor, stronger than Ken, Mike wor Tiana ate Cohendet, Christoph 26011 1124981 1134Sarah PCE Posoning = | Sienna | 4.4-346-0081U Corner oma wer eemHn TRUETYPE WOMEN FDINET pines 587 Campus Div T Stanford S106/Lony Loky Stem Gal Reseach ves toe any other time before. (V-5)MIZUTANI, (O-1)MIYAMICHI, and (V-4)BROWN all smelled the contents of (V-2)ZHAO's water bottle and confirmed that it had a strong odor of PFA. (v-2) ZHAO ended up throwing away the bottle. She does not remember @e2an ee ne where she left the water bottle on her desk the night before or where 9 it was before she picked it up to drink water. 10 11 (V-2)2HAO is also aware that (S)OUYANG is the suspect in the killing 12 of (V-3)RIM's stem cells. she also believes that (S)OUYANG is the 13 suspect in the tampering of her water. a4 15 (V-2)2HAO describes (8)OUYANG as very reserved and quiet. she appears 16 to be very anxious about things. (V-2)ZHAO did not interact with 17 (S)OUYANG very much because they are working on different projects. 18 19 20 (V-2)2HAO and (V-1)XING went to Vaden and had their blood drawn for 21 testing to check for abnormalities. 22 23 (V-2)2HAO often gets fresh water from the gym after working out. she 24 often works out with (0-1)MTYAMICHT. 25 26 NARRATIVE CONT'D 27 (¥-2)2HAO did not have a sample of the water from her incident on 28 Thursday 11/6/14 because she threw out the water bottle. 29 30 Next, I spoke with (V-5)MIZUTANI. ornicens mae wwnnen Bate SHETOAYGOFE ——-QUPERVSORA REVIEW ~IOMUMMER DATE race OF Kien, Mike wor ttianaets Cohendet, Christoph 25011 11/24/1495 1234REPORT FE SUPPLEMT L 347 (l(t) PC [F Poisoning {DEATON oF ORAL EET OF RRO ‘Tanna LAST FIAT OMET PM © BODES) DTT NOD 1387 Campus Drive / Stanford / 34308 / Lorry Lokey Stem Cail Research yyy, ‘Luling STATEMENT OF (V-5) MIZUTANI (V-S}MIZUTANI is a graduate student at Stanford University and has been in the Nusse Lab for about five years. She sits on the opposite side of the row of desks from (V-2) ZHAO. (V-5)MIZUTANI informed me that she had not personally experienced any incidents with her water, However, she is very concerned regarding i other contaminants other than PFA being present in her water. She 10 left her water bottle out on her desk over the weekend. The water 11 smelled normal, however, she did not try drinking it. 12 13 (V-5)MIZUTANI is also aware that (S)OUYANG is the suspect in the 14 killing of (V-3)RIM's stem cells. as 16 (V-5)MIZUTANI does not know (S)OUYANG very well because their lab work 17 does not really overlap. 1e 19 (V-5)MIZUTANT stated that she did smell (V-2)ZHAO's water bottle on 20 Thursday 11/6/14. The water in (V-2)ZHAO's bottle had a very strong 21 odor of PFA. 22 23 NARRATIVE CONT'D 24 (V-5)MIZUTANI was originally not considered to be a victim. However, 25 it was later determined by BC Laboratories that (V-5)MIZUTANI's water 26 bottle contained 0.11 ppm of Formaldehyde. Therefore, (V-5)MIZUTANI 27 is being treated as a victim. 28 29 I asked (0-1)MIYAMICHI if she had experienced anything unusual with 30 her water. orrceh sas resnmen DATE SHFTOSYSOF? ——_SUPERUSORSREVEW OMUMRER DATE pace oF Kirn, Mike por tinzta ete Cohendet, Christoph 2601) 44244851134SenaN Pe Posonng 14-316-0081U FELT Ba oy arto ae TR ai : 2 STATEMENT OF (O-1)MIYAMICHI 3 (O-1)MIYAMICHI is a graduate student at Stanford University and works 4 in the Nusse Lab. She sits next to (V-5)MIZUTANI. : 6 (O-1)MIYAMICHI informed me that she had not bad experienced any issues 7 with her water. (0-1) MIYAMICHI said that she had smelled (V-2)ZHAO's water a few times u 1. smelled (v-2)ZHAO's water on Thursday 11/6/14 and stated that it had in the past when it had an odor of PFA emanating from it. She also 12 a very strong odor of PFA on that day. 13 14 (0-1) MIYAMICHT works out with (V-2)ZHAO and sees her put water in her 15 bottle at the gym. 16 17 NARRATIVE CONT'D 18 I then spoke with (Vv-3)RIM. 1s 20 STATEMENT OF (V-3) RIM 21 (v-3)RIM is a graduate student at Stanford University and has been on 22 a permanent basis for almost a year and a half. she previously spent 23 time in the lab on a temporary basis from 9/2012 to 12/2012. 24 25 (V-3)RIM informed me that (S)OUYANG joined the Nusse Lab in 3/2014 on 26 a temporary assignment until 5/2014. She joined the lab on a full 27 time basis in 6/2014. (V-3)RIM acted as a mentor to (S)OUYANG and 28 worked closely with her from 3/2014 to 5/2014, Students will rotate 29 through various labs on a temporary basis before choosing a permanent 30 lecation, During that time, they work with another fuli time orrceRs nie onan are SuETOAYEOEF ——SUPERVEORS REVEW ——OMMEH ONT PAGE oF Kim, ike 207 Tana ate Cohendet, Christoph 26011 11aNA8s1 143dEA7ai PCF Potaoning Sen | Seren coca y 14-316-0081U EERO RAL ET OE SEAT FAST SEN FBT, 527 Campus Dive | Stanford / 8420 Lory Lokey Sta Call Research yer coe student. 1 2 2 (V-3)RIM considered (S)OUYANG a good friend and they worked well 4 together. However, they never spent time together outside of the 5 lab. 6 7 (W-3)RIM described (S)OUYANG as not very confident and was very quiet. 8 (S)OUYANG was very meticulous in her work and was a good student. 9 (W-3)RIM had no issues with (S)OUYANG. 10 11 (S)OUYANG also confided in (V-3)RIM regarding some personal issues. 12 (S)OUYANG mentioned how she had never had a boyfriend and envied 13 those that did. 14 15 (W-3)RIM then explained to me what happened to her research. she 16 works with stem cells and has been working on getting various stem 17 cells to successfully grow. She had to use various methods before 18 she was able to successfully grow the stem cells. 19 20 Sometime in mid-August, stems cells that she had been successfully 21 growing started to mysteriously die. There were no obvious causes 22 for the death of her stem cell samples. She had to start over and 23 she would successfully grow more stem cells only to have then 24 mysteriously die overnight. There were nights where she would stay 25 in the lab and check on the cells every two hours. The cells were 26 grown in a separate room across the hallway. The manner in which 27 they died was also very strange. The cells detached and floated up 28 dead. 29 30 Theoretically mouse embryonic stem cells would survive as long as she orriere we mame sare SHUETOAYE OFF ——=SUPERESORE REV NUMMER OATE pace oF Kirn, Mike mor TaNzita ete Gohendet, Christoph 26011 t1/at/14951 1534SaiewiPewPosenng MM S| etre Cann | 14-316-0081U LcaTioN de oman EVENT WE KOO ‘VIC NAN CAST FIRST WODTE IRN PBLSMESST Dopyrnoes. S57 Sapo ve 1 Stanford 9406 /Lony okey Stem Cal Reseach aye he 1 would like, because they can grow and divide indefinitely--stem cells are defined by their ability to do this. If they were unhappy for some reason, they would turn into another cell type, or some of then would die. So, the strange things ahout the cell death were: 1. They all died at the same time (all cells in a plate would be alive at one point then all dead the next time she checked, no survivors) ar) 2. They would detach from the plate and round up before dying (she 10 would only see this when she added the detaching reagent (Trypsin) to 11 move cells to a new plate, But she would keep the cells in detaching 12 reagent for few minutes then neutralize the reagent to avoid damage 13 to the cells.) 4 15 {V-3)RIM could not figure out what was causing her stem cells to die. 16 She thought that there could have been an issue with the incubator 17 she was using in room G2139. She placed some of her cells in an 18 incubator on the first floor in addition to some in the incubator she 19 normally uses in G2139, The cells on the first floor did not die, 20 hut the cells in room G2139 died, This pattern continued for some 21 time. She thought there was an issue with her methods or how the 22 experiments were being set up. She never thought that someone was 23 tampering with her cells. 24 25 On two occasions, (V-3)RIM's stem cells that she had in the first 26 floor incubator room also died. She had last checked on the cells on 27 10/9/14 and 10/16/14 only to find them dead the next day, 10/10/14 28 and 10/17/14 respectively. She initially thought that there was a 29 prohlem with her experiments that was causing her cells to die. 30 oebceies Wane Ben Gare SienArSOrF ——SuPERUgORS REVEW —IOMUMBER DATE ome oF in, ike wor tae ate Cohendet, Christoph 26011 11214951 1634ebont Tee SuPPiawE 347(aK1) PC [Fy Poisoning sane ® 14-316-0081U {DEATON OF RENAL EVENT GEC ‘VTi nan (AST FBT MODE FAO F BIGNESS” grTIDOS ‘337 Campus Drive / Stanford / 94308 / Lary Lokey Stem Cell Research ying, 1 ee aaah en 20 1 12 13 1 15 16 17 18 19 20 22 22 23 24 25 26 a7 28 29 30 On 10/23/14, sbe observed (s)OUYANG standing in front of her incubator with the door open. (V-3)RIM was tbe sole user of the “S2" incubator in room 62139. She asked (S) OUYANG what she was doing but did not get a clear answer and (S)OUYANG left the room. Since that incident, (V-3}RIM had a suspicion that (S)OUYANG may have been tampering with her cells. However, sbe still wanted to rule out the possibility of the cell death being caused by tbe equipment sbe was using. sbe started conducting experiments to see if she could rule out issues with tbe incubators as the cause of death. she also wanted to find out if she was being targeted. (¥-3)RIM placed some cells in her incubator, $2, like normal. she also placed some of her ceiis and intentionally misiabeled them, with “KB", and put them in ancther incubator. The cells labeled with (v-3) RIM's name in her incubator all died while the mislabeled cells in the other incubator did not die. She eventually informed Professor Roeland NUSSE, whose name the lab is named after. Througb working witb the administrative personnel in the building, they discovered that they had video evidence of (S) OUYANG going into the first floor incubator room shortly after (v-3)RIM left the room on botb 10/9/14 and 10/16/14. {S)OUYANG had no purpose for going into the first floor incubator room. She was not using any of the incubators for her own research. She was only using the incubators in room 62139. (v-3)RIM did not bave a copy of the video. (8)OUYANG is suspected of tampering with (V-3)RIM's stem cells. (V-3)RIM was never a victim of water tampering that she knows of. she Kin, Mike mor7 | tti2aess Cohendet, Christoph 2601 1NRINS981 1734:347(a)(8} PC [F] Poisoning {SEAT OF ORAL EVENT XIN 337 Campus Drive # Stanford / 84305 / Lorry Lokey Stem Gell Research iy ‘Oe ofthe Sheri Santa Cars Caen sana “ 14-316-0081U Vicia Hea CARY FST WOE PRON RISD TTD Liging esonr Fe ‘suPPLER a 1 uses a ceramic mug that she leaves on her desk but always empties out before she leaves the lab. NARRATIVE CONT*D Based on (V-3)RIM's statement, it seems to be clear that she was targeted by the suspect. No other student's stem cells died during this same time period. wee sa ey 10 I then spoke with (0-2)KIMMEY. a 12 STATEMENT OF (0-2)XIMMEY 13 {0-2)KIMMEY is a graduate student at Stanford University and is 14 currently on rotation in the Nusse Lab since mid to late September 15 2014, He works almost exclusively with (s)OUYANG and sits next to 16 her. They plan out and work on all of their work together. 17 Sometimes (S)OUYANG will stay after he leaves the lab, however, he 18 has no idea what she could be working on. She shouldn't be working 29 on their project by herself. 20 21 (0-2)KrMEY informed me that he had not experienced any issues with 22 his drinking water. He keeps his water bottle in a side pocket on 23 his backpack and never leaves the water bottle at his desk 24 overnight. 25 26 (0-2) KIMMBY describes (S)OUYANG as being unsure of herself and not 27 very confident in what she was doing. She would make last minute 28 changes to experiments that they had planned out together. 29 30 (S)OUYANG was very nice and looked up to the other people in the lab. Kim, Mike 207 Tanza ats Cohondet, Christoph 26011 THIZIH4951 1834Resor SUPPLE AL 1347(a}(1) PC [F} Poisoning BEG OF cma BENT OI ‘VicTOIRARC EAST FAST MOORE PEON F HIGREROT— DTryORO 397 Campus Drive 1 Stanford / 94306 / Lorry Lokey Stem Coll Research auc, a we eau en 10 an 22 a3 14 as 16 aw 18 19 20 22 22 23 24 25 26 27 28 29 30 [77 stated averse Dopo Pre Stes ‘Ofc ofthe Sherif, Sia ata Coast NERRATIVE 14-316-0081U Lisiing There were no signs of obviously odd behavior. However, (S) OUYANG rarely spoke with the other lab mates other than (V-3)RIM and himself. (8) OUYANG would on occasion leave her gym clothes on his chair and explain that she was "up late last night". Other than that, (0-2) KIMMEY does not know anything about (S)OUYANG's personal life. (0-2) KIMMEY had overheard other lab mates talking about their water smelling and tasting strange but he never noticed any reactions from (3) OUYANG. NARRATIVE CONT'D I then spoke with (0-3) LOGAN. STATEMENT OF (0-3}LOGAN (0-3) LOGAN is a post doctoral student at Stanford University and has worked in the Nusse Lab since 1998. Her desk is in the same bay as {V-5)MIZUTANI and (O-1)MIYAMICHI. (0-3) LOGAN informed me that she had not experienced any issues with her drinking water. (0-3) LOGAN did mention that a few weeks ago she got a new bottle of PFA and placed it at her workspace. She always replenishes her chemicals and does not leave near empty bottles of chemicals at her work space. She remembers using 5ml for one experiment and another 5ml for another experiment, but had not used the PFA after that. A bottle of PFA holds 100ml, which should have left about 90mi in the orr2ers MME ro mvere cate ‘SHIORYSO=F ——_-SUPFRVISORS REVEW RD MAMBER DATE pace oF ‘im, ike 2eo17ttvtartaate Conendet, Christoph 26011 HINE951 4934seromree marie 14-316-0081U 47(a)1) PC IF} Poisoning TSCATONGF ORGAN EVENT GOWN) ‘IST RAOE [AST FAT MORE FIAT PBUSRESON—— BHOGD 387 Campus Drive / Stanford 194306 / Lorry Lokey Stem Cell Research ny 1 Living bottle. On Monday when she checked her bottle of PFA, after 2 (V-1)KING's incident, she noticed that it was nearly empty. 3 4 (0-3)LOGAN stated that she assisted (S)OUYANG with her “Qual* on one 5 occasion, but otherwise not interacted with her much. A "Qual" is a 6 presentation before a panel regarding the purpose of one's research. 7 Repeated failure of a "Qual" could potentially lead to removal from 8 the program. She describes (S)OUYANG as being very shy, quiet, and 9 awkward. However, (S)OUYANG appeared to be more outgoing the last 10 few weeks. a 12 (0-3)LOGAN smelled (V-1)XING's water bottle on Monday 11/10/14. The 13 water smelled "off", but she couldn't say if it was PFA because her 14 nose is no longer sensitive to it. she had worked with PFA 15 extensively for many years and is no longer very sensitive to the 16 odor. a7 18 NARRATIVE CONT'D 19 I then spoke with (0-4)DIAzZ 20 21 STATEMENT OF (0-4)DIAZ 22 (0-4)DIAz is a graduate student at Stanford University and has been in 23 the Nusse Lab for about a month. He is in the Nusse Lab temporarily 24 as part of his rotations. He works with and sits next to 25 (v-1) XING. 26 27 (0-4)DIAZ informed me that he had not experienced any issues with his 28 drinking water. He never leaves his water bottle out overnight. 29 30 (0-4)DIAZ has not had many interactions with (S)OUYANG. However, imate Bor stant Senedak cistoph Bort aiewnesst "2 4revo 0 ‘suPeLEN ‘Stanford nines Dept of Pl Safty 347(a}1) PC IF] Poisoning trae Se a arc ~~ 14-316-0081U OLATIONOF ORGINAC VENT RADIAN ‘VETRANAN ART FRET WODLE PRU FLERE) BTFSOD 837 Campus Drive / Stanford / $4308 / Lorry Lokoy Stom Call Research ying, Ling 1 (S)OUYANG had once expressed that she was stressed out. 2 3 (Q-4)DIAZ witnessed (V-2)ZHAO's incident on Thursday 11/6/14. However, he did not smell the water. 4 5 6 NARRATIVE CONT'D 7 I then spoke with (V-4) BROWN a 9 o STATEMENT OF (V-4) BROWN (V-4) BROWN is a post doctoral student at Stanford University and works 11 in the Nusse Lab. Her desk is at the opposite end of the lab from 12. (8) OUYANG. 14 (V-4) BROWN informed me tbat she had not experienced any issues with 15 her drinking water. She does not leave her water bottle out 18 overnight. She brings fresb water from home every day. 18 (v-4) BROWN witnessed (v-2)ZHAQ's incident on Thursday 11/6/14, 19 (v-2)ZHAO said, "I think someone is trying to kill me!* (v-4)BROWN 20 smelled the water bottle and it had a distinct chemical smell, not 21 like mildew or mold. She mentioned that maybe it was tbe water 22 bottle that's causing the issue. 24 (V-4) BROWN also witnessed (V-1)XING's incident on Monday 11/10/14. 25 (V-4)BROWN smelled (V-1)XING's water bottle and it had the same 26 cbemical smell as (V-2)ZHAO's did on the previous Thursday. 27 {V-4)BROWN got a strong whiff of the chemical smell and it irritated 28 ber lungs, causing ber to cough. 29 30 (V-4)BROWN acted as an unofficial mentor to (S)OUYANG. She assisted ernie ws iorennes once STOAYSOEE ——SUPHRVSORE ANEW OMaIBER DATE Bick OF im, Hike peor7 hana ete Cohendet Christoph 26011 14RHaes} 71Nanwative SHED Permpomonng NPR L ‘Sacrum Stee Con oa 14-316-0081U ‘Geran oF Ona ENTE NDI ena FST FT OOLE PBST ‘337 Campus Drive / Stanford / $4308 / Lorry Lokey Stem Coll Research yng L wow 10 1 12 ey 14 15 16 a7 18 19 20 21 22 23 24 28 26 27 28 29 30 Liyjing (s) OUYANG with various experimental and career related conversations. (V-4) BROWN described (S) OUYANG as awkward and strange, but not having any glaringly obvious issues. NARRATIVE CONT'D I then spoke with (0-5) WANG. STATEMENT OF (0-5) WANG (0-5) WANG is a post doctoral student at Stanford University and works in the Nusse Lab. His desk is next to (V-4)BROWN’s desk at the opposite end of the lab from (s) OUYANG. (0-5) WANG informed me that he had not experienced any issues with his drinking water. (0-5) WANG stated that (S)OUYANG is currently working on research that he had started. He has regular work related interactions with (S)OU¥ANG about once a week. She is unsure of her project and her possibility of success. (0-5) WANG described (3)OUYANG as quiet, shy, and unsure of herself. She asks a lot of questions on procedural stuff that he would think that she should know. NARRATIVE CONT'D I left the Nusse Lab at about 1530 hours and was informed that (8) OUYANG had been placed on a WeI 5150 hold for evaluation at the vaden Realh Center. Vaden Health Center provides psychological races Me mM MBER o8re SHIEVRYS.O*F ——«SUPERSORS REVIEW OMUMER DATE race OF in, Mike mor Tinataaia Cohendet, Christoph 25011 tiztnaest 7244ReFORT TPE suPpLEM “Sanfod ineity Dep of abi Safer (aK) PCF Poieoning ‘tc eh Care Cn 14-316-0081U 537 Campus Dive I Sanford! 9496/Lory Lobe Stom Gal Research ng dagg | e 4 assistance to students in addition to numerous other services. 2 3 Due to the WEI 5150 hold, I did not have access to (S)OUYANG and was 4 unable to get a statement. 5 6 I placed the evidence into a locked closet in the locked Detective's 7 office over night. 8 9 20 On 11/12/14 at about 0800 hours, I booked the following evidence: a 22 1. Elimination prints from (V-1)XING, (V-2)ZHAO, (V-5)MIZUTANI, and 23 (0-3) LOGAN 24 2. (V-1)XING's white metal water bottle 15 3. (V-1)XING's silver metal mug 16 4. (V-5)MIZUTANI's blue plastic water bottle 27 18 At about 1134 hours, I called (0-7)HSU in an attempt to arrange a 19 meeting. I had to leave a message. 20 21 At about 1142 hours, I called (R)WAXMAN in an attempt to arrange a 22 meeting. I had to leave a message. 23 24 At about 1422 (0-7)HSU called and stated that he could meet me at the 25 SUDPS station in a few minutes. He arrived at the SUDPS station at 26 about 1430 hours. 27 28 STATEMENT OF (0-7) HSU 29 (0-7)HSU is a Stanford University employee. He is a graduate Resident 30 Dean in the graduate life office and has been working with(S) OUYANG, recs wae emawsen ate SHETAYS ORF ——-SUPERUSORS REVEW —OMUMGER DATE pace oF ‘Ki, ike 2eorr amarante Cohendet, Christoph 2601 1ZttS95t 233Reponr ne suPplemt 247|a\t) PC {F] Polsoning 14-316-0081U ‘oeaTen OF anal EVENT FF NOMS ‘MCTARRIRE RAST FIRST HDDIE FIRM PRN arog 387 Campus Drive / Stanford / $4908 / Larry Lokey Stem Cell Research agg, iMag L 2 3 4 5 6 7 8 s 20 aL 12 ey 14 15 16 a 18 19 20 22 22 23 24 25 26 27 28 29 30 providing University support since these events came to light. {0-7)HSU informed me that (8)OUYANG called him twice in the morning of 11/12/14 from the Stanford Hospital. At about 0648 hours, (S)OU¥ANG called and stated that she was confused as to why she was placed on a 5150 when she agreed to go to the hospital voluntarily. (S)OUYANG asked (0-7)HSU to help her leave the hospital. (0-7)HSU stated that he was unable to do that. At ahout 0627 hours, ($) OUYANG called again and immediately started hegging to he allowed to stay in school. she stated that she had done bad things hut, "not consciously* and "it was not myself”. (0-7}HSU asked what those had things were. (S)OUYANG just said, *T didn't mean to hurt anyone". {0-7)HSU asked, "do you mean the water hottles and the cells?" There was a brief silence, then (8)OUYANG said, "yes, but T did not know what I was doing and I did not want to hurt anyone* (0-7)HSU said, "Ok if you did not want to hurt anyone, can you please tell me what you put in the water?" (S)OUYANG said, "I don’t know. I don't remember. I just grabhed what was around, even tap water. I put it in my own hottle as well, tap water. T never do that hefore." (0-7)HsU asked, "please remember and tell me what chemicals you grabhed as people are scared and concerned about what they may have drank." (S)OUYANG insisted that she does not remember. im, Hike aor7 tate ts Cohendet. Christoph 26011 11721114961 243vor re ‘SUPPLE. res Dep a Plc Sarr JenaK Poon Sista aan om [- 14-316-0081U San LOCATION ORR EVEN OH “Weta WAVE ABT FIRST WoOLE PAW EUSMESSY BT 387 Campus Drive Stanford $4305 /Lotry Lokey Stem Cell Research yuu Lung 1 (0-7)HSU asked, "could it be PFA? Some people told us that they smelled PFA." (S)OUYANG said, “that is in the lab with many other thingseI really don't remember". (8) OUYANG then asked again regarding being able to stay in school. (0-7)HSU stated that discussion would need to happen in person. The conversation then ended. wera ae ern NARRATIVE CONT'D 20 On 11/12/14, at about 1346 hours, a Stanford University stay Away li Letter was issued for (S)OUYANG. Her official status with Stanford 12 University is unknown. 3B 14 15 On 11/13/14, I arranged to meet with (R)WAXMAN at her office located 16 at 300 Pasteur Drive in the Always Building. uy 18 STATEMENT OF (R) WAXMAN 19 (R)WAXMAN is an employee of Stanford University. She is the director 20 of faculty relations in the School of Medicine. 21 22 (R)WAXMAN stated that she learned of an issue regarding the possible 23 tampering of (V-3)RIM's stem cells around the last week of October. 24 (v-3)RIM had conducted experiments and Linda HENEGHAN, the building 25 manager at Lorry Lokey, found video of (8) OUYANG entering an area on 26 the first floor that she had no business being. (V-3)RIM's cells in 27 the first floor incubator died overnight on the two days that the 28 video showed (S)OUYANG entering that area. However, it was decided 29 that the issue would be handled in house without getting the stanford 30 Department of Public Safety (SUDPS) involved. crrcars same Ione ATE SHETORWSOFF ——-SUPERVSORS REVIEW OKUMHER OATE Pact oF ‘in, Mike 2017 Tata ate Cohendet, Christoph 28011 {1/2Wt4051 2834‘REPORT TV ‘SuPPLEMG Lb "| Stanford Lert Dee a Pale Safety r Jena) Pe Poteoning Cmeriwsmeacnces Te 44.346-0081U SARRATIVE (OCATENOF ORGNAL EVENT HE OD ‘ICTASMAYETAST FRET MOTE FPO FUSER BURTISOND 337 Campus Drive / Stanford / $4305 / Lory Lokoy Stem Gell Research yc, ‘using 1 2 (R)WAXMAN informed me that she had been alerted to an issue regarding 3 possibly tainted water when she was forwarded an email from Professor Roeland NUSSE on the evening of Friday 11/7/14 that (0-3)LOGAN sent him regarding drinking water tasting terrible and smelling like PFA. (R)WAXMAN then notified SUDPS Lt, COHENDET on Saturday 11/8/14. NARRATIVE CONT'D 11 (R)WAXMAN provided me with a copy of the surveillance video showing 12 (S)OUYANG entering the area of the first floor incubator on both 13 10/9/14 and 10/16/14 a couple hours after (V-3)RIM left the area. 45 At about 1441 hours, I called (0-6)GIBBS to find out if he had 16 received the results from the third party testing of the water 17 samples. 19 STATEMENT OF (0-6) GIBBS 20 (Q-6)GIBBS is an employee of Stanford University. He is the Associate 2% Vice Provost in the Environmental Health and Safety (=HeS) 22 department. 24 Sample 1 (white metal bottle) - (V-1)XING's water bottle tested 25 positive for Formaldehyde in the concentration of 840,000 ug/L 26 (840ppm) . 28 Sample 2 (blue plastic bottle) ~ (V-5)MIZUTANI’s water bottle tested 29 positive for Formaldehyde in the concentration of 110 ug/L 30 (0.110ppm) oorcsns wn orenmer ate [SHETOGYE.OFF ——_SUPERVISONS REVIEW —IOMUMAE GATE race oF Kien, Mike aeoir tangata Cohendet, Christoph 26011 T4zWIa9s1 2634Romirerecsnim MS) Smeaton | 14-316-0081U NARRAT TOCRTION OF BANAL EVENT IE OME, ‘isan AST FIRST WDSLE FRO RINESDY DDTODS 337 Campus Drive / Stanford ! 9430! Lorry Lokey Stem Cell Research inc, ti (0-6) GIBBS stated that drinking water should not have any amount of Formaldehyde in it. The concentration in Sample 1 is very high. He will be testing both the filtered water and the tap water from the break room. That water is commonly used by the lab personnel. NARRATIVE CONT'D we eran kene Paraformaldehyde is a polymer of formaldehyde. Formaldehyde is present 10 in paraformaldehyde. Per (0-3) LOGAN, PFA is used in the Nusse Lab as 11 a "fixative". It is used for preserving live tissue and cells. The 12 Material sagety Data sheet states it is a hazardous substance, It 13 can be toxic but there is limited evidence of carcinogenic effect. 14 . 1s 16 On 11/13/14 at about 2135 hours, I received an email from (V-2)ZHAO 17 that included an update to her first statement. ae 19 WRITTEN STATEMENT OF (V-2) ZHAO 20 A copy of the statement is attached to the case. The following is a 21 summary of the email. 22 23 (V-2)2HAO clarifies that her first incident was probably closer to 24 about one month ago, She believes that the actual date was 10/14/14 25 because she remembers that she was about to eit down and talk to 26 (0-5)WANG regarding a liver project they were working on together. 27 28 (V-2)ZHAO took one sip and felt a burning sensation then took a second 29 sip to confirm the burning sensation. She smelled the water and it 30 had a faint odor of PFA. She then started smelling her water before ‘erica we imine are SHETOAYSOR ——SUPERVKORSREVIEW ABER DATE pace oF Ki, Mike oi tananaata Cohendet, Christoph 26011 112114951 27kNARRATIVE {QEATON OF ORGINAL ENT HE OAD ‘ICTR GARY RAST OODLE PR POUSNESOY BTA 4337 Campus Drive / Stanford / 94305 Lorry Lokey Stom Cell Research yy iiseyneowons Sm + | rsirengttesss [414-316-008 1U Lidiing The second time she drank tainted water was on Thursday 11/6/14 as 1 2 3 4 mentioned in her first statement. She filled her water bottle at the 5 gym to about 75% full on Wednesday night. She left the water bottle 6 on her desk and left the lab at about 1900 hours, (S) OUYANG was still 7 in the lab when she left. 8 9 She was informed by Dr. Rich WITTMAN that the scent and taste of PFA 10 is detectable at about 50ppm (parts per million). Therefore, there 11 could have been many other instances of ingestion by her and others 12 in the lab where the concentration of PFA in their water bottles was 13 less than S0ppm. 15 NARRATIVE CONT'D 16 On 11/14/14, I watched the surveillance video and photos stills taken 17 from the video provided to me by (R) WAXMAN. 19 On 10/9/14 at about 2:15:20 PM z (V-3)RIM is seen entering the area 20 from the South West 1st Floor stairwell. 22 On 10/9/14 at about 2:31:09 PM g (V-3)RIM brings (S)OUYANG and 23 (0-2)KIMMEY to the area to show them where to temporarily store their 24 cells while she cleans the incubators in room G2139. (8) OUYANG is 25 the female subject wearing a white sweater, pony tail and glasses. 26 They entered the area from the South West 1st Floor stairwell. 29 On 10/9/14 at about 8:83:52 PM 2 (S)OUYANG is seen entering the area 30 from the South West 1st Floor stairwell by herself. She is carrying ‘orricuns nase roeuses Dare SHETOATSOFE ——SURERVSORS REVIEW LOMUMBER OMTE pace oF Ki, Mike poor tana ata Gohendet, Christoph 26011 11/2Naast 2834Share mreemme MK * | Smite 14-316-0081U OORTEN OF ORGAIAL EVENT HF CO ‘SERRE TST FRET MORE FAN F BUOMESD)— DTED 337 Campus Drive 1 Stanford / 94305 /Lorry Lokey Stem CeltReseorch yey Luvjing what appears to be a purple water bottle of sone kind. She is wearing a purple shirt, white sweater, ponytail and glasses. On 10/9/14 at about 8:59:52 PM z (S)OUYANG is seen entering the area from the South West Ist Floor stairwell by herself. She now has 1 2 3 4 5 6 gloves on her hands and is not carrying anything. 7 8 On 10/10/14 at abouti:08:04 PM ¢ (V-3)RIM is seen entering the area 9 from the South West 1st Floor stairwell by herself. 10 11 on 10/10/14 at about 2:57:02 PM ¢ (S)OUYANG is seen entering the area 12 from the South West ist Floor stairwell by herself. She is wearing a 13 lab coat. 14 15 On 10/16/14 at about 8:28:38 PM ¢ (V-3)RIM is seen entering the area 16 from the South West ist Floor stairwell by herself. a7 18 On 10/16/14 at about 8:34:41 PM zg (V-3)RIM is seen entering the area 19 from the South West ist Floor stairwell by herself. 20 21 On 10/16/14 at about 10:39:13 PM g (S)OUYANG is seen entering the area 22 from the South West 1st Floor stairwell by herself. She is holding 23 what appears to be a purple water bottle. 24 25 On 10/16/14 at about 10:39:13 PM ¢ (S)OUYANG is seen entering the area 26 from the South West 1st Floor staizwell by herself. She is holding a 27 pipettor in her right hand and an unknown bottle in her left hand. 28 29 30 T received an email on the night of 11/13/14 from (0-3)LOGAN stating orpears wae rome are erUAeS OFF SUPERIORS REVEW —OWUMBER OATE race oF Kim, tke reo itana ate Cohendet, Christoph 26011 H1RWIAest 7934eon 1 SupPLEME Stand University Dept. i Stee $347(aK) PCF Poisoning ‘tera Stn ens Cara Cea [ Ps 14-316-0081U LOCATON ORROWAL FEN HF OH ‘aa AST FHT WOE FE 337 Campus Drive / Stanford / $4305 / Lorry Lokey Stem Cell Research aye, 1 2 3 4 5 6 7 8 2 0 a 12 13 14 15 16 a7 18 1s 20 22 22 23 24 25 26 27 28 rT) Liujing that there were other water bottles that they would like to have tested. I will be meeting (0-6)GIBBS at the lab on 11/14/14 at about 1315 hours to collect those samples. On 11/14/14, at about 1102 hours, (V-3)RIM called me and we arranged to meet at 1230 hours. At about 1230 hours, I met with (V-3)RIM to get more information regarding the series of stem cell deaths that occurred to her cells. 2ND STATEMENT OF (V-3)RIM (v-3)RIM stated that she had used two out of three incubators in room @2139 to grow her cells. She used the "Top" and “Bottom” incubators, but primarily the "Bottom" incubator. When her stem cells started to die, they died every night. Every day that she plated new cells, she would find them dead the following morning. She tried various different reagents, incubators and methods but they all resulted in her cells dying when they had previous to the start of the incidents, grown well. She became very frustrated and stopped growing cells for almost all of September. On 10/8/14, (V-3)RIM went to the first floor and used the "External" incubator in G1165 because she thought there was an issue with the 29 incubators in room 62139. Her cells grew well for the first day. 30 She decided to clean out two of the incubators, "82" and "Bottom" in ‘FICERS WANE mae one SHPTOAYSGEF ———SUPERUSORSREVEW —OMMAER ATE pace oF Kim, Mike vor titastaeta Cohendet, Christoph 26011 11/24/4951 9034a —— Supe.) tit eng aay Serta) Pe Poisoning Saceraawaaccneces [~ 44-346-0081U 557 Campus Dive Stanford? 9906/Lory Lotey Stem Cal Resour yg tag 1 room G2139 to get rid of any possible causes of her cells dying. she asked (S) OUYANG and (0-2)KIMMEY to temporarily move their cells to the first floor incubator for two hours while she cleaned " "Bottom" in room G2139, (V-3)RIM took them downstairs and showed them the location of the first floor incubator, "External". 2" and san eu (8) OUYANG chose not to use the "External" incubator and moved her cells into the "Top" incubator in room G2139. She had no reason to eo go back down to the "External" incubator because she was not using 10 the incubator. n 12 On 10/10/14, she checked her cells in "External" and they were dead. 2B 14 On 10/16/14, she plated new cells and grew them in the "External" and 15 they were dead by morning. 16 17 She had also continued growing cells in room G2139. Her cells died 18 every night she plated new cells. 18 .20 Starting 10/20/14 she was the sole user of "S2". She also used 21 "Bottom" and "Top" in room 62139. 22 23 On 10/23/14, at about 1900 hours, she entered room 62139 and saw 24 (S)OUYANG standing in front of "s2" with the door open. (S) OUYANG 25 did not have any cells growing in "S2" and had no reason to be in 26 there. (S)OUYANG stated that she was checking on the water tray. 27 However, it is very unusual to check on the water tray of an 28 incubator that you are not using. There was also an open bottle of 29 Trypsin in the hood. Trypsin causes cells to detach and float up. 30 All of her dead cells floated up then died. (V-3)RIM left the lab at Kim, Mike mo17 | Ttataste Cohendet, Chwistoph 26011 t1aNt4es1 31peeorr vee supreme. Sonar Unvanity Dept of Pai Sater 34791) PC [F] Poisoning {exo oF omGRRL EVE AFD ‘Tae WAST PRET DD EPO PEVSNEEDN paeba ZIT Campus Drive / Stanford 94305 /Lorry Lokey Stem CellReseareN ye 1 Seesanneun u a 22 13 a a5 16 ay 18 19 20 21 22 23 24 25 26 27 28 29 30 14-316-0081U Liyjing about 2030 hours and returned on 10/24/14 at about 0630 hours to find her cells dead. The cells she was growing in "External" at the same time were still alive Another incident occurred on 11/4/14. (V-3)RIM plated new cells and checked on them at 1400 hours and saw that they were doing well. on 11/5/14 at about 0930 hours, her cells were dead. The last incident occurred on 11/5/14. She plated new cells at about 1130 hours. She checked on them at about 1900 hours and left the lab to go to dinner. Her cells were doing well at that time. After dinner she felt the need to check on her cells. She returned to the lab at about 2140 hours and all of her cells were dead. (3) OUYANG and (0-1)MIYAMICHI were the only ones in the lab. On Thursday 11/6/24 at about 1500 hours, (V-3)RIM went over the surveillance video footage with the building manager, Linda HENEGHAN, and observed (S)OUYANG entering the area near room G1165 on both 10/9/14 and 10/16/14. (v-3)RIM left for the weekend and did not return to the lab until Tuesday 11/11/14. She did not plate any cells after the last incident. (v-3)RIM provided me with a copy of her notes and observations that she had kept track of during the later period of her cells dying. She did not keep copious notes when the cells first started dying in mid August. The notes are attached to the report. NARRATIVE CONT‘D erect nome Diane OATe SHETONE OF ——-SUPERUISONS REVIEW OMLMER OATE race oF Kim, Mike or Hnzita ase Cohendet, Christoph 28011 1Havhager 9234347(aK1) PC IF] Poisoning NARREIVE ‘nenont TYPE ‘SUPPLEME f ‘Stanford University Dept of PutieSufety ‘tara eSeat Sa Carn Cowe 14-316-0081U LOEATON OF OfGNAL EVENT IF HOA ‘icTanau GST FAST BODIE Hw PBUGRESSD— BERTTOBS 4387 Campus Driva / Stanford / 94305 / Lorry Lokey Stem Cell Research yy Liyjing 1 At about 1310 hours, (0-6)GIBBS arrived at the lab. We collected a 2 Dasani water bottle off of (S)OUYANG's desk, a red water bottle from 3 (O-1)MIYAMICHI, and a green water bottle from (0-5)WANG's desk. 4 Samples were provided to (0-6)GIBBS from all three of the bottles. 5 6 (S)OUYANG's water bottle was taken because she mentioned that she also 7 put things in her water. 8 9 (0-1) MIYAMICHT's water bottle was taken because she is now concerned 10 that her water was also tainted. The water does not have an odor of 11 PFA. She did not drink her water. 12 33 (0-5)WANG's water bottle was taken because his water bottle was left 24 out on his desk for an extended period of time and he is concerned 15 that his water was also tainted. He has not drunk from his water 16 bottle in about a year. W 18 At about 1325 hours, I took elimination finger prints from (0-5)WANG. is 20 21 At about 1335 hours, f took elimination finger prints from 22 (0-1) MIYAMICHT. 23 24 25 At about 1440 hours, I returned to the Stanford DPS station and booked 26 the following pieces of evidence. 27 28 1. (S)OUYANG's Dasani water bottle 29 2. (O-1)MIYAMICHI's red water bottle 30 3. (0-5)WANG's green water bottle orFceRs wae iwnumen ate ‘SHFTDANS OH —«SLPERUSCRE Revit —OSUOCR DATE ine Kirn, Mike ei? taza ate Cohendet, Christoph 26011 THI2114951 33 BeseronT TE SUPPLERE [Santo igo Pea tT} PC Poisoning (GeaTIONF oRHAL EVENT FNC 337 Campus Drive / Stanford! 4308 / Lorry Lokey Stor Cell Research 1 2 3 4 5 6 7 8 9 10 aw a2 a 14 15 16 17 18 ig 20 21 22 23 24 we 14-316-0081U 5 iOoTE wane | Lining 4, Elimination prints from (O-1)MIYAMICHI and (0-5)WANG At about 1610 hours, I called (0-7)HSU to inquire if he had spoken with (S)OUYANG again, (0-7)HSU stated that he went to the hospital and spoke with (S)OUYANG last night. During that conversation, (S) OUYANG admitted to (0-7)HSU that she had used a pipettor to place PFA in two water bottles. She got the PFA from her own bay or area around her desk. (S)OUYANG did not mention the amount of PFA she used or the number times she put it in the water bottles. (0-7) HSU did not provide any more information. As of this moment, I still do not have access to (S)OUYANG. She is still at the Fremont Hospital. I am waiting to hear when she will be released from the hospital to locate her and get a statement. P.L-E.O. Det. KIM supes gio Original Report Det. FLOERCHINGER SUDPS 14 Assist/Elimination Prints sgt. HOM supes C3 Supervisor End of Report DFEICERE MANE ‘oranach one SWEUOAVEOH ——SUPERVBOREREVEW —DRRMBER DATE pace OF im, ake zsoiTihataote Gohendet, Christoph 26011 T1/zi/1g951 3434‘Sanford University Public oABe NO EVIDENCE eoreR oy =STOEN MISC Fei EVORNSE MDEWEANOR “GR = SAPEKEEDING Fer" EVIOENGE FeLowy "= SEMEO TEM ‘DESCRIBE PROPERTY BELOW J¥E FOLLOWING SEGUENCE: CODE, TEM TYPE, BRAND, NCUEL, COLOR, SERIAL NUMBER, 14-1594, STeRED LOCATION €OD6 JF SUBMITTED INTO THE PROPERTY ROCME JALUE. FENNUMEER DESCRIPTION (ING CATBER, SLADEGR BARREL LENGTH AMD LOGATION FOUND. ISG INGILDE THE RECOVERED — [v0 CODES: = LOCKER NUMBER ke = REFRIGERATOR Sa ee = ee on = er Sea ‘ Elimination Prints from ¥-1, V-2, Q(and 2-4” _(o-t) 16 wow (v-S/(o-4) 6 Now &3) Lory Lokey 62145 FROST TCE [RA ees eae se SETS 7 vere [tebe ‘ |V-1's water bottle containing possibly tainted water SON ToRD Lony Lokey 62145 SSS eS eae pea sar eee a = 7813, Mt 7 ‘ 1 \V-1's metal cup that previously had tainted water in it Lorry Lokey G2145_ SSS cae eS a aes paar 7 7814 Mu 1 SPlasticwaterbote (oN) 6 Now (v-5) Lokey 62145 KIM Mike Ka866 [iano | roto 1prerear re “Sianford University Public Jase No Isc EVIDENCE 1444 EVIDENCE MSDEMEANOR “Seu AFEXEEDNG atom “or sOTveR. FEF" EVIDENCE FELONY “paseimen rene ‘prs FOUN ' aSTOEM =RECOVERED [cc COnES ua =L0c¥en wuMBeR ‘DESCRIBE PROPERTY RELOW IN THE FOLLOWING SECUENCE: CODE, TEM TYPE, SRAND, UODEL, COLOR. SERIAL NUMBER. ‘REFRIGERATOR VAsUE PEN NUMBER DESCRIPTION (MC EAIUER, HADEOR GARREL LENGTH, AD LOCAMENFGING AsDINeWeE He |r” CpmeeoER STORED LOCATION SODE IF SUBMITTEDINTO THE PROPERTY ROCA fy «Diora PROP OD cone [OP pane rea ae PLT pau reo 7619 | te (S)OUYANG's water hottie left on her desk focarenraue ony Lokey 62145 TROIS cose ERO OS aT CHET ane ra = 7e20 {archon 2 (0-t)Miyamich's water bottle from her desk TORT Lorry Lokey G2145 So cae | no rene ee ne eRe = Te24 Mt “ (0-5)WANG's water bottle from his desk ETT FOORT Lomy Lokey G2145 SSE EE ea ae PET = 7e22 ele 4 Elimination Prints trom (O-4)Miyamichi and (0-5)Wang Lorry Lekey 62145 KM, ike ___ | e866 [11/4014 “7 . rode i)SRI4-4594) Ber sssrar y SHie wary a92392 mad Bony ONZ > DEIZD J weyers SeA ALISUBAINN G8O3NVLS 83H . wee ieee] wma] s+ | wo NooU ses -40 ONIGING HOUVASEY TD WaLls Aa4OTSR14-15944 WOLyTN! prota is) BUL Gecrewaned wood ~ 591 @ [He meow [Mioeacer 3 vopomoin senses g aa woe uome| se ALISHBAINN GHOJNVIS ONIGTING HOwVSSSY 1739 WALS ASOT as ToeSB Laboratories, Inc. 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English only Formaldehyde in Drinking-water Background document for development of WHO Guidelines for Drinking-water QualitySR14-15944 WHO information products on water, sanitation, hygiene ang health can be freely downloaded at bttovAwww.who.intwater sanitation health! © World Health Organization 2005 ‘This document may be freely reviewed, abstracted, reproduced and transtated in part or in whole but not for sale or for use in conjunction with commercial purposes. Inguities should be addressed to: permissions@who.int, ‘The designations employed and the presentation of the material in this document do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries ‘The mention of specific companies or of certain manufacturers’ products does not imply that they are endorsed or recommended by the World Health Organization in preference to others of a similar nature that are nat mentioned, Errors and omissions excepted, the names of proprietary products are distinguished by initial capital letters. ‘The World Health Organization does not warrant that the information contained in this publication is complete and corcect and shall not be liable for any damages incurred as a result of its use.Preface ‘One of the primary goals of WHO and its member states is that “all people, whatever their stage of development and their sovial and evonomic conditions, have the right to hrave access to an adequate supply of safe drinking water.” A major WHO function to achieve such goals is the responsibility "to propose ... regulations, and to mieke recommendations with respect to international health matters..." ‘The first WHO document dealing specifically with public drinking-water quality was published in 1958 as international Standards for Drinking-water. ewes subsequeally revised in 1963 and in 1971 under the sazne title, Tn 1984-1985, the first edition of the WHO Guidelines for Drinking-water Quality (GDWQ) was published in three volumes: Volume 1, Recommendations; Volume 2, Health criteria and other supporting jnformation; and Volume 3, Surveillance and control of community supplies. Second editions of these volusnes were published in 1993, 1996 and 1997, respectively. Addenda to Volumes 1 and 2 of the second edition were published on selected chemicals in 1998 and on microbial aspects in 2002. The third edition of the GDWQ was published in 2004, and the fitst addendum to the third edition was published in 2005, ‘The GDWQ are subject to a rolling revision process. Through this process, mlcrobfal, chemical and radiological aspects of drinking-water are subject to periodic review, and documentation relaed to aspeets of protection and control of public drinking ‘water quality is accordingly prepared and updated. Since the frst ediion of the GDWQ, WHO has published inforiation on health criteria and other supporting inforination ta the GDWQ, describing the approaches used in deriving guideline values and presenting critical reviews and evaluations of the effects on fusian heaith of the substances or conteminants of potential health soncern im drinking, water. In the first and second editions, these constinsted Volume 2 of the GDWQ. Since publication ofthe thid edition, they comprise a series of free- standing monogrephs, including this one. For each chemical contaminant or substance considered, a lead institution prepared 2 background document evaluating the risks for human health from exposure to the particular chemical in drinking-water. Institutions from Canada, Denmark, Finland, France, Gemmuany, Tinly, Japan, Netherlands, Norway, Poland, Sweden, United Kingdom and United Staies of America prepared the docurvents for the thd edition and addenda, Under the oversight of a group of coordinators, each of whom was responsible for @ group of chemicals considered in the GDWO, the draft health criteria documents were submitted to a number of scientific institutions and selected experts for peer review. Comments were taken into consideration by the coordinators and authors. The draft documents were also released to the public domain for comment ard submitted for final evaluation by expect meetings. During the preparation of background documents and at expert mestings, careful consideration was given to information available in previous risk assessments carried ont by the fatemational Programme on Chemical Safety, in ts Environmentel Health SR14-1594)SRI14-15941 Criteia monographs and Concise international Chemical Assessment Documents, the Intermational Agency for Rescarcit on Cancer, the Joint FAO/WHO Meetings on Pesticide Residues and the Joint FAOWHO Expert Committee on Food Additives (which evaluates contaminants such as lead, cadmium, nitrate and nitrite, it addition to food additives) Further up-to-date information on the GDWQ and the process of their development is available on the WHO Internet site and in the current edition of the GDWQ,SRI4-15944 Acknowledgements ‘The first draft of Formaldehyde in Drinking-water, Background document for development of WHO Guidelines for Drinking-water Quality, was prepared by Mr JK. Fawell, United Kingdom, ta whom special thanks are due. The work of the following working group coordinators was crucial in the development of this document and others contributing to the first addendum to the third edition: Dr. Cotruvo, J. Cottuvo Associates, USA (Materials and chemicals) Mr LK. Fawell, United Kingdom (Naturally occurring and industrial contaminants) Ms M, Giddings, Health Canada (Disinfectants and disinfection by-products) Mr P. Jackson, WRe-NSF, United Kingdom (Chemicals ~ practical aspects) Prof. Y. Magara, Hokkaido University, Japan (Analytical achievabifity) Dr E, Ohanian, Environmental Protection Agency, USA (Disinfectants and disinfection by-products) ‘The draft text was discussed af the Working Group Meeting forthe first addendum fo tho third edition of the GDWA, held on 17-21 May 2004, The final version of the document takes into consideration comments from both peer reviewers and the public. ‘The input of those who provided comunents and of participants in the meeting is spratefully acknowledged, ‘The WHO coordinator was Dr J. Bartram, Coordinator, Water, Sanitation and Health Programme, WHO Headquarters. Ms C, Viekers provided a tixison with the International Programme on Chemical Safety, WIIO Headquarters. Mr Robert Bes, Water, Sanitation and Health Programme, WHO Headquaiters, provided input on pesticides added to drinking-water for public heslth purposes, Ms Penny Ward provided invaluable administrative support at the Working Group ‘Meeting and throughout the review and publication process. Ms Marla Sheffer of Ottawa, Canada, was responsible for the scientific editing ofthe document. Many individuals ffom vatious countries contributed to the development of the GDWQ. The efforts ofall who contributed to the preparation ofthis document and in particular those who provided peer or public domain review comment are greatly appreciatedAcronyms and abbreviations used in the text Chemical Abstracts Service deoxytibonveleie acid empty bed contact time Food and Agriculture Organization of the United Nations ‘granular activated carbon Guidelines for Drinking-water Quality International Union of Pure and Applied Chetnistry ‘median lethel dose no-observed-adverse-eflect level novobserved-effeet level part per million ribonueteic acid World Health Organization SR14-15941‘Table of contents 1, GENERAL DESCRIPTION LL Identity, 12 Physicochemical properties 13 Orgsnoteptic properties 1.8 Major ses and sources in drinkiog-weter 2. ENVIRONMENTAL LEVELS AND HUMAN EXPOSURE. 2 Air... 2.2 Water, 2.3 Food vs 2.4 Estimated lotal exposure and relative contribution of driaking-watcr. 3, KINETICS AND METABOLISM IN LABORATORY ANIMALS AND HUMANS 4. EFFECTS ON LABORATORY ANIMALS AND ZV PITRO TEST SYSTEMS....3 4.4 Aeate exposure... - - 4.2 Short-term exposure. 43 Longsterm exposure 44 Reproductive and developmental toxicity 4.3 Mutagen en eats ed-poins 4.6 Carcinogenicity 5, EFFECTS ON HUMANS. 6, PRACTICAL ASPECTS... 6.1 Analytical methods and analytical achiovabilty. 6.2 Treatment and control methods and technical achievabitity 7. CONCLUSIONS... 8, REFERENCES SR14-15941SR14-159411. GENERAL DESCRIPTION grpi4-1594! LL Identity CASNo: 50.00.00 Moleculseformsia; CHO ‘The IUPAC name for formaldehyde is methanel. 1.2 Phystcoctremical properties! (Bills etal, 1977; Verschueren, 1983; Acheson et al, 1984a; IPCS, 1989) Property Yate Physical state Colours gas Boiling point 92" Meting point usec Relative density 1.04 ir=1) Vegour pressure S26KPaat-33°C Water salubitty realy miseble at 25°C. Log octmol-water partition coofiient —-E 1.3 Organoteptic properties Formaldehyde has a pungent, suiTecating, hay- or straw-like odour. Taste and odour tosholds are 50 and 25 magfitre, respectively (Bills etal, 1977; Verschueren, 1983). 14 Major nses card sources in drieking-water Formaldehyde in drinking-water arises mainly from the oxidation of natural organic (humic) matter during ozonation (Glaze et al, 1989) and chlorination (Becher et al, 1992). It also enters drinking-water vie leaching from polyacetal plastic Bitings in which the protective coating has been broken (1PCS, 2002), Formaldehyde’s main industrial use is in the production of urea-formaldehyde, pheaolic, melamine, pentaerythritol, and polyacetal resins. Its second largest use is in the industrial synthesis of a number of organic compounds. It is also used in cosmetics, fungicides, textiles, and embalming fluids (IPCS, 1989). 2. ENVIRONMENTAL LEVELS AND HUMAN EXPOSURE 21 Air Formaldehyde is emitted into air from plastics and fesin giues. Low levels in air may also result from the photo-oxidation of hydrocarbons derived fiom fossil fuel. Typical levels in air are a few micrograms per cubie metre, Smokers are exposed to high levels of formaldehyde (US NRC, 1980; IARC, 1982; IPCS, 1989), * Conversion faster ini: 1 ppm =12 mln’ 325°C. 1sr14-15941 FORMALDEHYDE IN DRINKING-WATER 2.2 Water In water, formaldehyde is hydrated and folind largely in the form of methylene glycol and its oligomers (PCS, 1989; OECD, 2002). Formaldehyde concentrations of up to 30 gfitre have been found in ozonsted drinking-water (Krasner et aly 198% ‘Tomkins et al, 1989). In a study in Taiwan, formaldehyde concentrations in bottled and packaged drinking-water were all below the detection limit of 129 jegllitre (Chia- Fen et at, 2003). 23 Food Concentrations of formaldehyde ranging from 3 to 23 righkg have been reported in a variety of foods (IARC, 1982). 24 Estimated total exposure and relative contribution of drinking-water ‘The general population is exposed to formaldehyde mainly by inbalation, staokers receiving about 0.38 mg/day by this route (US NRC, 1980; IPCS, 1989), People are also exposed in food, from the use of urea-formaldehyde foam in housing insulation, and from the use of cosmetics containing formaldehyde. Drinking-water tested with ozone is unlikely to contain formaldehyde. ot concentrations exceeding 50 pxylitre and so will be a miner source of exposure, It is tunceriain whether boiling will have 2 significant impact on the concentration of formaldehyde in drinking-water. Formaléchyée is considered to be highly soluble in svatet, and its Henry's law constant (3 x 10° kParm’/mol) suggest tat it willbe very Unlikely to volatilize from water. Exposure by inhalation during showering is therefore expected 10 be lov. This view is supported by experimental data from ‘Takahashi (1990). 3. KINETICS AND METABOLISM IN LABORATORY ANIMALS AND ‘HUMANS “The kinetics and metabolism of formaldehyde have been reviewed by IPCS (1989, 2002), Ingested formaldehyde is readily absorbed by the gastointestinal trac. In dermal studies, it was absorbed less readily in monkeys than in rats or guines-pigs (Geficoat, 1983) It appears to be distributed mainly io muscle, Tower levels being ‘ound inthe intestines, liver, and other tissues (Bhatt eta, 1988). Formaldehyde is rapidly oxidized to formic aci; the subsequent oxidation to carbon Gioside and water is slower in monkeys than in rais (McMartin et al, 1977). Other metabolic products, such as_—NN-bisthydroxymethyl}uren and Ne (hydroxymethyDjurea, nave been reported in rats (Mashford & Jones, 1982). ‘Metabolites are eliminated in the urine, faeces, and expired air, the relative amounts depending on the route of administration (Galli etal, 1983; Upreti et al, 1987; IPCS, 1986).FORMALDEHYDE IN DRINKING-WATER 4, EFFECTS ON LABORATORY ANIMALS AND IN VITRO TEST SYSTEMS: 4.1 Acute exposure Oral LDss of 800 and 260 mg/kg of body weight have been reported for the rat and guinea-pig, respectively (Smyth et al, 1941). 42 Short-term exposure Ina 4-week study, Wistar rats (10 per sex per dose) received formaldehyde in drinking-water at doses of 0, 5, 25, or 125 markg of body weight per day. Rats receiving the highest dose showed lowered food and liquid intake, histopathological changes in the stomach (Le., focal hyperkeratosis of the forestomach, moderate papillomatous hyperplasia), and, in males only, lowered total protein and albumin levels in plasma. The NOABL was 25 mg/kg of body weight per day (Til et al,, 1988; IPCS, 1989), ‘Oral doses of 0, 50, 100, oF 150 mg/kg of body weight per day in rats and 0, $0, 75, oF 100 mg/kg of body weight per day in dogs for 91 days had no effect on haematology, clinical chernisiry, utinalysis, or gross microscopic pathology. Depression in body: ‘weight gain was observed in both species at the highest dose levels and in male rats given 100 mg/kg of body weight per day (Johannsen et al., 1986), 4.3 Long-term exposure Ina 2-year study, Wistar rats were exposed to formaldchyde in drinking-water nt ‘mean doses of 0, 1.2, 15, or 82 mgrkg of body weight per day for males and 0, 1.8, 21, co 109 iag/kg of body weight per day for females. The average concentrations of formaldehyde in the drinking-water were 0, 20, 260, and 1900 mgytire inthe contro, fow-, mids, and high-dose groups, respectively. Adverse effects were observed only in animals receiving the highest dose and included lower foo and liguid intake, lower ‘body weights, and pathological changes in the stomach, characterized by thickening ‘of she mucosal wall. Relative kidney weights were increased in high-dose females, ‘and an increased incidence of renal papillary necrosis was found in both sexes. Exposure did not appear to affect survival, haematology, or clinical chemistry. The NOEL was 15 mg/ky of body weight per day, or 260 mg/ltre (Til etal., 1989). tna similar study, Wistar rts were given formaldehyde in drinking-water at 0, 10,59, ‘or 300 me/kg of body weight per day. At the end of 12 months, rats of both sexes in the high-dose group were observed to have gastric erosions, ules, squamous cell hhyperplosia, hyperkeratosis, and basal cell hyperplasia. Only one male and one female fiom the mid-tose group showed hyperkeratosis (PCS, 1989; Tobe ta, 1989), g$R14-15941FORMALDEHYDE IN DRINKING-WATER 44 Reproductive and developmental toxicity No teratogenic effects were reported iu mice given formaldehyde at oral doses of 0, “74, 148, of 185 mg/kg of body weight per day on days 6-15 of yestation (Macks etal, 1980). Growth and viability of neonates from mice given oral formaldehyde doses of 540 mgfkg of body weight per day on days 8-12 of gestation were unaffected {Seidenberg et a, 1987), No effects on reproductive performance or on the health of offspring were observed in beagle dogs fed 0, 3.1, or 9.4 mg of formaldehyde per ke of body weight yer day inthis dst on days 4-56 after mating (Hurni & Ohder, 1977), Sperm shnornulities were observed in male rats given single oral formaldehyde doses of 100-200 mg/kg of body weight (Cassidy et al. 1983), Intraperitoneal injection of formaldehyde at & or 16 mgikg of body weight per day for 10 days resulted in degeneration of testicular tissue, inkibition of spermatogenesis, and lowered male reproductive organ weights in rats (Shah et a, 1987) 4.5 Mutagenicity and related enit-points Formaldehyde has shown evidence of mutagenicity in prokaryotic and eukaryotic cells in viro, 1 has also been shown to be genotoxic in Drosophila niclanogaster. Formaldehyde binds readily to proteins, RNA, and single-stranded DNA to induce DNA-protein cross-links and breaks in single-stranded DNA. It reacts readily with macromolecules in cells, mainly at the point of exposuce (Ma & Huns, 1988). Jn. vivo, formaldehyde increases both DNA syathesis in rats (Overman, 1985) and the umber of micromuctel and nuclear anomalies in epithelial cells in rats (Migliore et al, 1989). 46 Carcinogentctty ‘There is little evidence that formaldehyde is carcinogenic by the oral route, In a 2° year study in which Wistar rats were exposed to formaldehyde in drinking-water at ‘mean doses of 0, 1.2, 15, or 82 mg/kg of body weight per day for males and 0, 1,8, 21, or 109 mg/kg of body weight per day for females, exposure did not appear to affect tumour incidence (Vil et al, 1989). In a 2-year study in which Sprague-Dawley rats were exposed ta formaldehyde in drinking-water at dose levels of, 1,5, 10, 50, 100, ct 150 mg/kg of body weight per day, 2 dose-dependent increase in the incidence of {eukaemia (mainly lymphoblastic) and lymphosarcoma was reported at dose levels of, 3 mgfkg of body weight per day or greater. The increase in the incidence of {gastrointestinal neoplasms was not dose-related. Tumours of this type were rare in historical controls and not detected in concurrent controls (Soffit etal, 1989), In a carcinogenicity study, 2 group of 10 rats was given drinking-water containing 0.3% formalin (0.2% formaldehyde) for 32 weeks. Histopsthological changes were observed in the stomach, as well as neoplastic changes in the forestomach and papillomas. In addition, the authors reported evidence that formaldehyde fad tumour~ promoting activity. However, because of the presence of high levels of methanol in formalin, she usefulness of this information is limited (Takahashi et al, 1986). In 4 SR14-15944another study, formléchycle induced omithine decarboxylase activity (an indication of tumour-promoting activity) in rats given a single oral formaldehyde dose of up to 100 rag/kg of body weight (Overman, 1983) There is no evidence that formaldehyde acts as 2 eatcinogen or promoter when applied to mouse skin (Krivanek et, 1983), ‘There is evidence that inhalation exposure to formaldeiyde causes cancer in rats and mmive by imitating the nasal epithelium. Rats exposed to formaldehyde at 17 mg/m", 6 bh per day, $ days per week, for 2 years exhibited na increased incidence of squamous cell carcinoma ofthe nasal cavity. Tamours were also noted in mice at the same level ‘of exposure, but this species was less sensitive than the rat (Swenberg et al, 1980; Kems et al, 1983). A number of other long-term studies by the orai route have been conducted, and these are reviewed in detail by Restani & Galli (1991) and IPCS (2002). The conclasion of these reviews was that formaldehyde is 2 normal mammalian metabolite and is not carcinogenic at low levels of exposure. S. ERRECTS ON UUMANS Intation and allergic contact dermatitis have been associated with exposure of the ‘skin to formaldehyde at levels higher than those encountered in drinking-water (Cosmetic, Toitotry and Fragrance Association, £984). ‘There is some evidence that formaldchyde is a carcinogen in humans exposed by inhalation, Epidemiological investigations of the mortality of factory workers, following prolenged occupational exposure to formaldehyde showed a slight excess of lung cancer thet was not related to formaldehyde exposure (Acheson et al. 19842,b). An increase in the incidence of nasopharyngeal cancer was also noted but ‘again did not appear to be related to formaldehyde (Collins et al, 1988). Further studies of groups who have been occupationally exposed to formaldehyde by inkalation fave largely supported this position but provide more evidence that formaldehyde may possibly pose a carcinogenic risk of lung or sino-nasal eancer, and possibly lymphoid lenkaemis, in occupationally exposed groups (Coggon ct at, 2003; Hauptmann et al., 2003, 2004; Pinkerton et al,, 2004). However, all of the authors ‘urged caution in interpreting thet dat. 6, PRACTICAL ASPECTS 6.1 Analytical methods and analytical achlevabitity Formaldehyde in drinking-water is generally determined by a high-performance fiquid chromatographic method following derivatization with 2,4-dinitsopkenylhydrazine and liquid solid extraction. The detection limit is 62 pgslitee (US EPA, 1991).FORMALDEHYDE IN DRINKING-WATER gri4-15941 6.2 Treatment and control methods ad teclinieal achievability ‘Concentrations of formaldehyde in water, which arise mainly from the oxidation of natural organic matter during ozonation and chlorination (see section 14), may be reduced by changes to disinfection practice or by GAC ‘treatment to below 0.03 meylitre Biological filtration, using dual media san&/GAC or sand/anthracte coal as media, hhas been evaluated forthe removal of aldehydes, including formaldehyde. Pilot filters were operated at 14 mvh (EBCT 21 min), receiving raw water following pre- ozonation, coagulation, and sedimentation. Two types of virgin GAC (wood and coal-based) were used, The influent concentration of formaldehyde to the Gikers (typically 7-12 mglitre) was reduced by 50% after <2, <15, and & days. for anthracite, coal-based GAC, and wood-based GAC, respectively. For the same media, 80% removal was achieved alter 36, 18, and 15 days. GAC developed biological activity sooner than anthracite and was also @ better bio-support medium (Krasner et al, 1993). ‘A study off fil-scale treatment plants in France showed that formaldehyde concentrations increased to 2-4 times the raw water levels (1-25 suglitr) following ozonation, Subsequent GAC filtration reduced formaldehyde concentrations to about ‘the raw water levels (Jammes etal, 1995). Anthracite/sand biological pilot filters (EBCT 7 tin) gave, approximately 85% removal of formaldehyde from 2 feed concentration of about 10 jolie. Back ‘washing using chlorinated water (1 mg of chlorine per litre) gave poorer removal than. tackwashing with non-chlorinated water (Miliner et al,, 1995), In a study with sand filters operated with different contact tines, formaldchyee levels were reduced by 60% after a 2-min EBCT, but no further removal occurred with EBCTS up to 7 min (influent concentration 7 p/itre) (Wang 8 Sumuners, 1996). 7, CONCLUSIONS Rats and mice exposed to formaldehysle by inhalation exhibited an increased incidence of carcinomas of the nasal cavity at doses thst caused irritation of the nasal epithelium (Swenberg ct al, 1980; Kerns et al., 1983). Ingestion of formaldehyde in =] and <= 10 times the occupational exposure level: Use air-purifying respirator with full face piece and HEPA particulate filters with either cartridge(s) or canister specifically approved for protection against formaldehyde, or a full fuce piece powered air-purifying respirator fitted with IEPA particulate filters and with either cartridge {s) or canister specifically approved for protection against formaldehyde. For formaldehydeSR14- 15944 concentrations >10 and < 100 times the occupational exposure level: Use Type C full face piece supplicd-air pressure-demand or continuous-flow respirator. For formaldehyde concentrations >= 100 times the occupational exposure level or unknown concentration (such as in emergencies): Use positive-pressure self-contained breathing apparatus with full face piece. Type C positive-pressure full face pioce supplied-air respirator with an auxiliary positive-pressure self-contained breathing apparatus escape system. Protective gloves: Wear impervious gloves according to the manufacturer's recommendation or use butyl rubber. Skin protection: Wear impervious clothing. Eye protection: Wear chemical goggles. Additional clothing and/or equipment: Bye wash station, Exposure Guidelines See Cormposition/Information on Ingredients (Section?) Section 9 Physical and Chemical Properties Appearance and Physical State: White free-flowing solid prill. ‘Odor (threshold): Strong, pungent formaldehyde odor Specific Gravity (H20=1): 0.81 — 0.84 amv’em3 @ 20% (68 *F) ‘Vapor Pressure (sam Hg): 5.0 mm HgA Vapor Density (air=1): (Calculated values); Formaldehyde = 1.04 Water = 0.62 Methanol =L1. Percent Volatile by volume: ND Evaporation Rate (butyl acetate=1): ND Boiling Point: Does not boil, Gives off formaldehyde gas when heated. Freezing point / melting point: 120 ~ 170 °C (248 ~ 338 °F) pH: 6.9 (1% solution in water @ 25°C) ° Solubility in Water: Slowly in cold water @ 20°C Molecular Weight: Formaldehyde = 38. Water = 18. Methanol = 32. Section 10: Stability and Reactivity Stability: Stable Conditions to Avoid: Temperatures above 100 °F (38 °C), sparks, flame. Materials to Avoid (Incompatibility): Caustic soda, lime and other strong alkalis; sodium, potassiura and other alkali metals, hydrochloric, sulfuric and other strong inorganic acids, nitrogen oxides, amines and oxidizing agents such as peroxides, nitric acid, perchloric acid, chromium trioxide, phenols or urea, Hazardous Decomposition Products: Formaldehy vapor: CO, CO2 Hazardous Polymerization: Will not occur. ‘arbon monoxide. Formaldehyde Section 11: Toxicological Information Results of component toxicity test performed: Acute Exposure: (Oral, Rat): LDSO = 680mg/kg; slightly toxic to animals. (Inhalation, Rat): LCSO: 1070mg/m3 (4 hus., dust); slightly toxic to animals, Skin: Severely irritating with necrosis to rabbit skin with a 24 hr. exposure period; slightly toxic to animals (LDSO, Rabbits: >2000mg/ke). Eye:Ra assy, Severely imitating with ulceration/necrosis in rabbit eyes. Repeated Exposure: An inhalation exposure study was conducted in rats (6hrs. /day; 5 days/week; 2 weeks) with paraformaldehyde as a respirable dust at concentrations of 23, 55 or 150 mg/m3. Formaldehyde was also present at concentrations of 3.5, 4.7 and 18 mg/m3, respectively. ‘Exposure was stopped during the first week for the middle and high dose groups due to high mortality. Inflammation of upper respiratory tract tissue was noted in these groups. No treatment-related effects were observed at the low dose. A 6-week oral exposure study was conducted in rats with paraformaldehyde in drinking water at concentrations equivelent to 5, 25 or 12Smg/kp/day. Other than decreases in growth and food & water intake in the high dose, no significant effects were noted. Mutagenicity: Positive in the in vitro mouse lymphoma forward gene mutation systems. Produced sister chromatid exchanges, but not chromosomal aberrations in the mouse lymphoma in vitro system. No in vivo information. Paraformaldehyde breaks down in water to product formaldehyde. Acute Exposure (Formaldebyde): (Oral, Rats): LDSO =: 800mgikg; slightly toxic to animals. (Inhalation, Rats) LC50= 474ppm (4 brs.}; moderately toxic to animals. Skin: Severely irritating/cosrosive to rabbit skin depending on exposure duration and concentration; moderately toxic to animals (1D50, Rabbits: 270mg/kg); causes skin sensitization in humans and guinea pigs. Eye: Severely irritating to rabbit eyes, Repeated Exposure: Inhalation exposuro (Shes. /day; 5 days/week; 13 weeks) of rats resulted in nasal tissue irritation at 10 or 20ppm, but not at 2pm. Monkeys exposed for 26 weeks (22hts, /day; 7 days/week had nasal ircitation at 3ppm but tot at tppm. Oral exposure of ats to formaldehyde in the drinking water at a dose equivalent to 82-109 mg/kg/day over a lifetime resulted in stomach tissue invitation while a dose of 15-21 mg/kg/day was without effect. ‘Mutagenicity: Genotoxic potential was noted in a variety of in vitro systems. Results in vivo have been mixed probably due to the presence of metabolic processes for detoxifying formaldehyde. Carcinogenicity: Oral-Formaldehyde was not carcinogenic in a well-conducted lifetime drinking water study in rats at concentrations equivalent to 82- 109 mg/kg/day. Dermal-Topical application on mice has not indicated carcinogenic potential. Inhalation-Rats and mice were exposed to 2.0, to 5.6 or 14.3ppm formaldehyde for Ghrs, /day, 5 days/week for 24 months. In rats no treaiment-refated tumors were seen at 2ppm while at 5.6ppm 1% had nasal tumors and at 14.3ppm. Reproductive/Developmental Effects: In a developmental toxicity study with mice dosed orally by average at 74, 148 or 185 nig/kg/day, no fetotoxic or teratogenic effects were ‘seen, In a developmental toxicity study with rats exposed via inhalation t0 2, 5 or Lppm formaldehyde, trcat-related developmental effects were not observed. in a reproduction study, dogs received the equivalent of 9.4 mg/kg/day of formaldehyde in feed! during days 4-56 after mating without adverse reproductive effects. Human experience: Causes skin sensitization in humans ‘This product dees contain compounds listed by NTP or [ARC or regulated by OSHA as a carcinogen. Section 12: Ecological Information Feological information: Aquatic toxicity studies with paraformaldehyde in fish indicate slight acute toxicity: Rainbow trout) 96-br. LC50 = 60ppm; (Catfish) 24-t-TLm = 32pm; (Flounder) 48-hr. TLm = 100-300ppm. Paraformaldehyde breaks down in watergrpi4- tse to formaldehyde. Ecological information on formaldehyde is listed next, Formaldehyde exhibits slight acute toxicity to various fish species. The 24-, 48-and 96-hr. LC50 values (bluegill sunfish, trout, bass, salmon, catfish, carp, golden orfe) are in the range 10- 1000ppm. Algae and some invertebrates appear more susceptible; e.g,, noute toxicity ‘occurs in green algae at 0.3-0.Sppm and in the water flea (daphnids) at 2-52ppm (24/48- br. EC50), Formaldehyde bes bactericidal properties at low levels. (ECS0, E. coli=lppm), Chemical Fate Information: Formaldehyde: The short atmospheric half-life, the low a- octanol/water partition coefficient and the ability of animals & microorganisms to rapidly biodegrade formaldehyde are expected to lead to its ready removal ifreleased into the environment, Degradation: Formaldehyde in aqueous effluent is degraded by activated sludge and sewage in 48-72 bts. In a die-away test with lake water, degradation was complete in 30 hrs under acrobic conditions and 48 hrs under anaerobic conditions. Atmospheric photochemical degradation is rapid with estimated half-lives of 19hrs or Jess, Biogccumulation: The log n-octanol/water partition coefficient is 0.35. This suggests that formaldehyde has relatively low potential to bioaccumulate, Section 13 Disposal Considerations RCRA 40 CER 261 Classification: 0122. ‘This information applies to the material as manifactured; processing, use, or contamination may make this information inappropriate, inaccurate, or incomplete. This handling and disposal information may also apply to empty containers, liners and rinsate, Federal, State and local laws governing disposal of materials can differ. Ensure proper disposal compliance with proper authorities before disposal. ———— Section 34: Transportation Information US DOT Information: Proper shipping name: Paraformaldehyde Hazard Class: 4.1 Packaging group: fff UN Number: UN2213 IATA: Proper shipping name: Paraformaldehyde Hazard Class: 4.1 Packing group: It UN Number: UN2213 IMO: Proper shipping name: Paraformaldehyde Chass: 4.1 UN Namber: UN2133 Packing group: 1 EMS: 133 ‘FAG: BD ‘Marine Pollutant: Not listed Canadian TDG: Proper shipping name: Paraformaldehyde IMDG Page: ND Limitations: ND Section 15: Regulatory Information United States Federal RegulationsZimbra hitps:t/zm)5.pobox s'~>ford eda/zimbradb/printmessagetid-C:88845., Zimbra SR14-15941 mkkim@stanford.edu Re: Investigation in your tab From : Dani Zhao ‘Thu, Nov 13, 2014 09:35 PM Subject : Re: Investigation in your lab To : Mike K Kim Hi Mike, Upon further reflection, I believe thet the first time that Inoted a burning sensation after drinking water from my water bottle probably about t month ago. Most likely October 14. The reason why I know this date is because I know I was about to sit down and taik with Bruce about the liver project that we're working together on. And because of that, I think it was most likely right after he presented some new data at lab meeting that day. This first time was in the early afternoon. I took one sip of water, felt the burning sensation, then took another sip to confirm the burning sensation, I smelted the water and it smelled faintly like paraformaldehyde (PFA). I dumped out the water and washed the bottle with soap and water. From there forward, I would notice that the water smelled like PFA (most often) if I left the water bottle in lab over the course of 2 days (i.e. over the weekend), but sometimes if I left it out for just 1 night. I go to the gym Monday, Wednesday, and Fridays, And sometimes, I might add water into the bottle at the gym without smelling it and then would drink it, But I never noticed @ burning sensation in these instances. Since the first instance of strange water, I would usually smell the water in the bottle before I drank it. If it smelled even faintly like PFA, I would dump out the water and wash out the bottle with soap and water (although the last few times that It happened, I would just rinse the bottle ‘out thoroughly with tap water). The second time I drank tainted water was last Thursday, November 6, around 5:30-6pm. The water in the bottle had been brand new the previous night...I filled it ~75% full at the gym on Wednesday evening (I left lab Wednesday evening around 7pm or so, at which time I know Xiangyu was stil in lab). When I drank the water (large gulp) on Thursday 11/6, the burning was terrible. It was in my mouth, in my throat, and my eyes started to water. I spit all the water out and rinsed my mouth out. I then went to the kitchen with my coffee mug and drank water from the filtered water source there, When I came back to the lab, I smetied the water and it smelied much stronger of PFA than it had ever smelled for me before. I confirmed this with others wha were still in the lab at the time (Makiko, Hinako, and Kate). At the time Xlangyu and Giovanni were alsa in the lab. Maybe Sam as well. After I confirmed the smell with Kate, 1 threw out the bottle and the remaining liquid in the bottle. Upon reflection of this second instance, when i came back to the bottle, by pure weight of the bottle, it seemed like perhaps there was probably less water in there than what I would have expected after just one gulp given that I had filled it up quite a bit the night before. Finally, J wanted to give an update. You were probably contacted by now that the EH&S reports 1of3 rv1ai2014 7-21 AN‘imbra bttps:/2m05.pobox.st ford edu/zimbravh/printmessage?id-C:88845, 74-15941 ame back and both water samples that were tested, tested positive aka contained formaldehyde (the form that PFA takes in water). One of the samples (Liujing’s water) contained much more formaldehyde than the other, at a level of 840ppm. According to Larry Gibbs, the EH&S head, this amount of formaldehyde contamination could only have occurred by tampering. Furthermore, Dr. Rich Wittman told us that 50ppm formaldehyde is the level at which many people will be able to detect an odor or taste. Thus the fact that we could smell the PFA in the ‘water, means that it was a concentration of at least SOppm. However, this also means that just because we didn't detect a smell or a taste or a burning sensation (i.e. drank our water without noticing anything), it does not mean that there wasn't PFA in the ingested water. ‘Thope this clarifies my timeline and my exposure to the tainted water. Sorry I wasn't able to get this statement to you earlier. It's been another long day of meeting after meeting. Best, Dani Zhao MD/PhD Candidate || Year 5 Stanford Schoo! of Medicine || Laboratory of Dr. Roeland Nusse danizhao@stanford.edu || 650-906-0134 On Thu, Nov 13, 2014 at 3:35 PM, Mike K Kim wrote: Hello Liujing and Dani, I know that both of you were victims of tainted water a few times every week since it was first discovered, however, Ineed to know how many times you actually ingestes the tainted water before smelling it ‘As much detail as you can provide would be very helpful. However, don't worry too much if you cannot remember the dates and exact number of times. Thank you Detective Mike Kirn Investigations Division Stanford University DPS 850-222-8826 Celi From :Mike K kim ‘Thu, Nov 13, 2014 03:35 PM Subject : Investigation in your lab To :I}xing@stanford.edu, danizhao@stanford.edu tania 721 AYTEATS BRIGRAL BENT OWT 1337 Campus Drive / Stanford / $4305 / Lorry Lokay Stom Coll Research | sig, 1 2 3 4 5 6 7 8 9 10 a 12 23 14 15 16 aT 18 19 20 2a 22 23 24 25 26 27 28 29 30 eae Sopa “Siafod Uivry ope of Pe ates 347(a)(1) PC [F] Poisoning ‘Oca he Shen, Sent Clara County Sans 14-316-0081U cr ASE FAST MDELE TON FASSESEISTHISBS Liujing SR 14-1594F LISTED INFORMATION ATTACHMENTS Copy of Evidence Sheet (s) Copy of the sketch I used with (s)OUYANG to determine seat location for individuals in the Nusse Lab Copy of the Stanford University Stay Away Letter (8) OUYANG - No cH / cuIC NARRATIVE On 11/16/14, at about 1331 hours, Sgt. HOM called and informed me that (8) OUYANG may be released from the Fremont Hospital into the care of her mother sometime today. We were both released from working the Stanford Football game and went to the SUDPS station to discuss our next steps. We both changed out of our uniforms into plain clothes. We did not know if or when she was going to be released from the Fremont Hospital. However, based on the fact that we would not be able to locate (S)OUYANG if she left the campus, we decided to watch her residence to see if she comes back to get her belongings. At about 1540 hours, Sgt. HOM and T went to (S}OUYANG's residence on campus, 119 Quillen Court, in an attempt to locate (S)OUYANG. We went up to her room (#401) and noticed that the door was slightly ajar. I went up to the room and heard a male voice and a female voice. I recognized the male voice to be (0-7)HSU's voice. I did not recognize the female voice, I also heard what sounded like rustling of plastic bags. I believed that the people in the room were packing. Sgt. HOM and I went back out the front door and we sat ovrigens wae ‘Demat cate SAT BAG OW | SUPENTOORS REV WMANEER [DATE ar Kim, ike 2e017 tana 37 Cohendet, Christoph 26011 2184952 148supreme, | ‘Stanford Uaersity Dope of be any PE PaTnk) P6 FPotoning Scalers Secon Ce fe 44-316-0081U TER ON GF OGRA EVENT TF NO VeTar ne ART FST, MOTCE Fa HOERERST pros 4337 Campus Orive | Stanford / 94205 Lorry Lokey Stem Cell Research | sage, Ling down at a table located outside of the building near the front door. We were watching and waiting for (S)OUYANG to exit the building. At about 1602 hours, I saw another Graduate Resident Dean Laurette BEESON walking out of the building witb a clear plastic garbage bag. She looked straight at us as she carried the plastic bag out of the building. Both sgt. HOM and I have worked with BEZSON on numerous occasions and I am sure that she recognized us. She soon reentered wea rane ene the building. sgt. HOM went to check for other exits. S iL At about 1625 hours, I saw (0-7)HSU walking out of the building with 12 two large suitcases. (0-7)HSU looked over at me and informed me that 13 (8) OUYANG was inside ber residence packing. He soon reentered the 14 building empty handed. 16 At about 1640 hours, (0-7)HSU came out and informed me that he was 17 going to retrieve bis vebicle to assist (s)OUYANG move her belongings 18 off campus. He reenters the building at about 1658 hours. 20 At about 1706 hours, (0-7)HSU came out of the building with two more 21 guitcases. He soon reenters the building empty handed. 23 At about 1713 bours, (0-7)HSU came out of the building with a laundry 24 basket. He soon reenters the building empty handed. 26 At about 1720 hours, (S)OUYANG exits the building with her mother, 27 (0-7)H8U, and Laurette BEESON. 29 At about 1721 bours, Sgt. HOM and I make contact with (S) OUYANG at 30 (0-7)HSU's vehicle. We informed (3) OUYANG that we had a paper to etn OE BME aE sim ~TSaETONS OR ERENCE ENON —[NinmeR [ATE ke roi tana ga7 [Cohendet, Christoph | 26011 | 11/21/14 952) aa 2 8[ReeonT Tee at “MT Pe (Poisoning Were ‘tere See ean Cn . 14-316-0081U TSERTGR SE CREAT EVENT TF HOT 337 Campus Drive J Stanford / 96305 Lorry Lokey Stem Colt Research eer anneone 10 1 12 13 14 15 16 Wy 18 13 20 a1 22 23 24 25 26 27 28 29 30 reer TM NAME LAST FRET MODE PUNT BUSREST —— 2TADS XING Ltujing give her and that would like to speak with her. She verbally said, "yes" when we asked if we could speak with her, We attempted to Jecate a quiet room in the first floor of the Quillen Highrise, however, the only available rooms were occupied. We walked over to the tables located outside of the front doors of Quillen Highrise. At about 1726 hours, Sgt. HOM advised (S)OUYANG that she was not under arrest and the we were here to serve her with the letter and to talk with her, Sgt, HOM again asked (S)OUYANG if she was willing to talk tous. She verbally said, *yes*. I gave (S)OUYANG a copy of the Stanford University stay Away Letter, The letter states that she is barred from Stanford University or any other land or property owned or leased by Stanford until further notice. I asked (S)OUYANG if she knew that she would be served a Stay Away Letter. She stated that she had not been previously informed that she would be served with a Stay Away Letter. She was informed by the graduate dean that she was being placed on a leave of absence for at least a year. She read the letter in front of me and informed me that she understood the contents of the letter. sgt. HOM informed (S)OUYANG that violating the provisions in the letter could possibly lead her to being arrested for trespassing. (8) OUYANG stated that she understood. (s)OUYANG and I beth signed the original copy. I informed (S) OUYANG that we were notified of a series of incident that occurred at the Lorry Lokey building and that it would be appreciated if she would be willing to speak with us xegarding them. (s) OUYANG again verbally said, "yes". Without further prodding or ne reuse) aE BeRTOASOF | SupeRSGREREVEN Drank | BATE moe OF im, ko e017 tart. 937 Cohendet, Christoph 26011 11214982 348SEaNNeereotonng ET ‘Siinartesea enc 14-316-0081U aC aa EF ERE aT ing | questioning, (S) OUYANG began telling us about the incidents that occurred at Lorry Lokey. (S)OUYANG's statement was recorded on my department issued digital recorder. STATEMENT OF (S) OUYANG | (8) OUYANG is a graduate student at Stanford University and has been in | we oa eee the Nusse Lab as a full time member since the beginning of the Fall 10 quarter, 2014. she worked in the Nusse Lab as a part of her one year 11 rotation from the end of March until May. At the end of her one year 12 rotations, she chose to work in the Nusse Lab because she really | liked the advisor, Professor Nusse, the environment of the lab, and 14 the people in the lab. | 16 (S)0UYANG informed me that she started to suffer from severe insomnia 17 and dizziness starting in September 2014, She sometimes felt a 18 disconnection from reality and didn’t know what she was trying to 19 achieve when she was "doing that". She was not aware or planning of | 20 what happened. she understands that it was misconduct. 22 She was discharged from Fremont Hospital for a psychological condition 23 on the condition that she continues the treatment and recovery back 24 in Singapore with psychiatric care. 26 (S)QUYANG clarified that she put ‘Trypsin in her own cells and to 27 another 24 well plate belong to another student. She repeated twice 28 that the cells belonged to "another student", I asked her for the 29 mame of the "other student and she said, "Ellen". (Ellen is 30 (W-3) RIM). Kim, bike peotr sgwaga? [Cohendot, Christoph 25011 T1/zuteas2 4a |347(aK}) PC fF] Poisoning wer ane we 10 1 12 43 14 15 16 1 18 19 20 an 22 23 24 25 26 27 EATEN SF ORGRIL BENT RIOR 387 Campus Drive / Stanford ! 34306 £ Lorry Lokey Stor Coll Research | iy ta sure > ‘Gaaked avery ‘Oe of te Shr Sat lars Couey Sieera 14-316-0081U ACTIN CAST, FRET OTE ERA BUINESSY TENE (S) OUYANG then stated that she didn't know whose cells were in the 24 well plate that she put Trypsin in. She put Trypsin in her own 24 well plate also, the cells in her 24 well plate detached and most of them died. she also used a 12 well plate and a 6 well plate. Those cells did better; however, she doesn't remember putting Trypsin in those plates either. (8) OUYANG explained to me the purpose of Trypsin. Cells attach themselves to the surface, Trypsin is used to make the cells detach so that researchers can collect the celis. The collected cells can be moved and used for other purposes. It takes some time for the cells to detach then it takes some time for the cells to die once detached. She does not know how long it would normally take detached cells to die. (3)OUYANG could not remember the room number where the cells were handled. However, there is one main cell culture room that she used located directly across from the Nusse Lab. She could not remember if the plates were clearly labeled. She said that she initially didn't know whose cells she added Trypsin to, but she did confirm that she added Trypsin to a 24 well plate that did not belong to her. She again stated that she added Trypsin to her own cells to kill them, but she could not explain why she did it. I asked (S)OUYANG if there was a cell culture room on the first floor. She replied, "I think so". She stated that she never grew her own 28 cells in the first floor, I asked her if she even knew where the 29 incubator was located on the first floor and she said, "I do", she 30 never put her cells in the incubator on the first floor. she Kine Ror “uainesar Gohan, Chstoph 2e0t1 tUatsaee2| ssaL 2 3 4 a 6 7 8 9 10 a 12 B p44 1s 16 17 18 19 20 21 22 23 24 25 26 a7 28 29 30 ferent ee wi supruw ot “Sanford Univeraty Dept of Public Safety 2479} PC [Poisoning ‘the ate Soe oss Con [: * 44.316-0081U [237 Campus Drive / Stanford / 94305 Lorry Lokey Stem Celt Research ARRIVE, DENTON OF ORGHAL ETE We RO bine GET FHGT ODL FONE args XING Liying confirmed that she had been in the room on the first floor. She stated that she doesn't know why she went into that room but tried to explain that it was something like sleep walking. She stated that she "somehow" went there, at that time, she was psychologically unstable, depressed, stressed and very dizzy. Sometimes the dizziness caused her to not be fully conscious of what she was doing. (S) OUYANG stated that a few months ago she went and spoke with a counselor about her condition. She spoke with the counselor about three to four times then was referred to a psychiatrist at the same center. The psychiatrist prescribed her with some anti-depressant medication. She could not remember the name of the anti-depressant. ‘The anti-depressant caused her headaches to become worse. The dizziness caused her to not be herself, Due to the dizziness, she stopped using the medication. (S)OUYANG stated that she did not have any issues with other people in the lab. I asked (3) OUYANG if there were other things that happened in the lab. (S) OUYANG asked, "that concerning the water bottles?" she stated that it started with occasionally putting dish washing detergent in her own water at home and drinking it. The water tasted like kitchen detergent, but she did not suffer any negative side effects. She j stated that she never put anything into her roommate's water. At the lab, she added random things into her own water bottle. sbe grabbed chemicals that were at her bench and put them in her bottle. “arvaeswine pik | BSE gre OFF —~ [SureRnEsaS RENEW — OnaneER [AE Kim, ke mor | tettaga7 JConendat, Christoph 26011 aad sw v2site 982,ena NPE simu 247iay() PC (FI Poisoning “Seaford Usher Depa of Pile Seety ‘Otee afte Ser, ane Clara Coen cr 14-316-0081U 10 an 12 3 14 a5 16 a7 18 a9 20 22 22 23 24 25 26 27 28 29 30 TOSRTGN OF GaIGRL BURNT GF RRO 1387 Campus Drive / Stanford 4305 /Locry Lokey Stom Coll Research | wig Vices AST FAST HODLE PION FANNIN ——2IETAGES Liang Wer work bench is next to her desk. She stated that she did not mix the chemicals, hut put only one chemical in her hottle at a time. She stated that she used Millipore water which she explained to he some type of purified water. (according to a quick internet search, Millipore water is filtered water and is safe to drink). She also put either 4% or 16% of PFA into her own water. When asked if she had any adverse reactions to drinking PFA, she avoided the question and stated that she was not in a good mental state. she did clarity that the PFA that she used was from a small hottle and not from the little vials. Under normal circumstances, (S)OUYANG always reduces the 16% PFA (the hottle of PFA normally used in the lab is a 16% concentration) down to 4%. She could not remember if she put 4% or 16% PFA into her water. She stated that she could smell the odor in her water, hut again did not answer whether or not she had any reactions to drinking the PFA. she against stated that she had heen suffering from very heavy dizziness. (s)ouvaNG admitted to putting PFA into a white water hottle. She did not know who the bottle helonged to. The white water hottie was in the next bay over. (S)OUYANG is in the first hay. I drew a quick sketch of the Nusse Lab including the four separate hays that makes up the lah. I pointed out the first hay where (S)OUYANG has her desk. TI then pointed out the second bay and stated that there were two desks on the left of the hay and two on the right side of the hay. All of the desks were on the far side of the wall furthest from the entry door. (S)OUYANG initially stated that she thinks the white bottle was on the first desk "straight, facing the door”. She then said that the white orice wae ToNuuee ATE SurTORG oF SUPERVEORE REVIEW | DNUMRER Cane Pace oF Kim, Mike mo17 zt 837 Cohendet. Christoph 26011 1120/14082 748REPORT TPE . Santrd Unieniy Dep o Pic Sey NARRATIVE Seren Pe (FPoleoning _ ncaa See Ca Ce [:- 14-316-0081U eee SneaaT eae om canon VISEMNAWEGAST FRET WDGLE RN FAUSSESS) ——yaTHTOSO 337 Campus Drive | Stanford 194308 / Lorry Lokey Stem earth | Ng Liang 1 bottle was one of the two desks on the left side of the second bay. She was also able to tell me who sat at each desk. Left side of Bay 2: 1.Giovanni (0-4)DIAZ sits at the desk nearest the wall 2.Liujing (V-1)XING sits at the second desk from the wall eran eon I asked hex if she put PFA in any other water bottles. (3) OUYANG 9 stated that she put PFA in another water bottle that looked similar 10 to the white water bottle she already admitted to tainting. We ll asked her again if she knew the names of the people whose water 12 bottles she put PFA in because we needed to let those individuals 13 know to get checked out medically. (S)OUYANG stated that she may 14 have put PFA in a water bottle located on the right side of the 15 second bay. 16 17 I asked (8)OUYANG to tell me who sits in at the other desks. 18 19 Right side of Bay 2: 20 1.Dani (V-2)2HAO sits at the desk nearest the wall 21 2.0pen desk sometimes used by an undergraduate student. Currently 22 unoccupied. 23 24 I asked (S)OUYANG to tell me who sits at the desks in the third bay. 25 She said that she doesn't remember who sits in there. I informed 26 (S)OUYANG that we tested water in a bottle taken from the left desk 27 nearest the wall and that it came back positive for PFA. I informed 28 (S)OUYANG that the desk in question belongs to "Makiko", 29 (V-5)MIZUTANE. 30 Kir, Mike Lagi Tata 937 Gohendet, Christoph 26001 1112114952, 8Revoarnee ‘SUPPLENE ‘Sianied sive Dee ot Pie Stey 347(a)(1) PC [F] Poisoning Offre te Shei, Sn Clorx County ve 14-316-0081U | icrnroue GaST FAT MOE RTO SISNESID— BTORS pone Living TSERTER GF ORAL BENT OF RO 537 Campus Drive 1 Stanford / 94208 Lorry Lokey Stem Call Research 1 (8)OUYANG stated that she only goes to that bay when she needs to order supplies. She pointed to one of the desks in the third bay and stated that no one that at that desk and the lab computer was there for people to use to order supplies. I then asked (S)OUYANG who sat next to (V-5)MIZUTANI. She immediately said, “I know it's Hinako, I think". ear a ween Left side of Bay 3: 10 1.Makiko (V-5)MIZUTANI sits at the desk nearest the wall 41 2.Hinake (O-1)MIYAMICHI sits at the second desk from the wall 12 33 Right side of Bay 3: 24 1,Cati (0-3) LOGAN sits at the desk nearest the wall 15 2.Lab Computer 16 17 When asked if (O-1)MIYAMICHI's water bottle was affected, (8) OUYANG 18 said, "no", then went on to say that she seldom goes to the third 19 bay. She only goes there to order supplies. She did not answer the 20 question when asked if she put PPA in (V-5)MIZUTANI's water bottle. 21 (S)OUYANG only stated that she did not go te the desk area in the 22 third bay. 23 24 Right side of Bay 4: 25 1.Bruce (O-5)WANG sits at the desk nearest the wall 26 2.Kate (V-4)BROWN sits at the second desk from the wall 27 28 (S)OUYANG stated that she never goes to the fourth bay because it is 29 so far from her work space. Kien, Mike 25017 sets 937 Gohenidet, Christoph 26011 11214952] 9 18 |