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Hematology Case Study ID No: 1104148

Questions 1. The name of the graph used to determine the [Hb] of the patient is the Cyanmethaemoglobin Standard Curve 2. The concentration of the patients Hb is 6.8g/dl 3. RBC Indices MCV - 0.24/3.5 1000= 68.6 fl range (80 100) fL range (32 36) % range (27-31) pg

MCHC- 6.8/0.24 = 28.3% MCH- 6.8/3.5 10 = 19.4pg

4. The patients RBC morphology will show that the RBC's are smaller than normal and have an increased zone of central pallor. This is indicative of a hypochromic (less hemoglobin in RBC, low MCHC value) microcytic (smaller size of RBC low MCV value). There will be a increase in anisocytosis (variation in size) mainly microcytic and poikilocytosis (variation in shape) which would include target cells, pencil cells and ovalocytes. 5. The next step to determine RBC morphology is to perform confirmatory tests which includes ferritin, serum iron testing and bone marrow biopsy 6. The clinical term used to describe the state or condition of the patient is Hypochromic Microcytic Anaemia 7. To ensure that the result from graph is correct the formula can be used.

8. Iron deficiency anemia - A ferritin level test, which reflects how much iron may be stored in the body. Abnormally low ferritin levels may point to iron deficiency anemia. This is one of the first tests to be abnormal when you have iron deficiency. Anemia of Chronic disease confirmation of the diagnosis can be obtained with a ferritin level. Ferritin is a measure of iron stores, but it also is an acute-phase reactant whose concentration in the blood increases during acute and chronic inflammation. Thus, in

iron deficiency, the ferritin level is typically low, whereas in ACD, the ferritin level is often high.

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