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  • Diazepam (Valium) Drug Study

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    Emika Dizon
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    This document summarizes information about the drug Valium (diazepam). It is used as an adjunct to treat anxiety, for preoperative sedation, and conscious sedation. It works by potentiating the inhibitory neurotransmitter GABA in the central nervous system. Side effects include dizziness, drowsiness, respiratory depression, and dependence with prolonged high dose use. When administering diazepam, vital signs should be monitored and the injection site checked for phlebitis if given intravenously.

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    drug study for diazepam

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    Diazepam (Valium) drug study

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    This document summarizes information about the drug Valium (diazepam). It is used as an adjunct to treat anxiety, for preoperative sedation, and conscious sedation. It works by potentiating the inhibitory neurotransmitter GABA in the central nervous system. Side effects include dizziness, drowsiness, respiratory depression, and dependence with prolonged high dose use. When administering diazepam, vital signs should be monitored and the injection site checked for phlebitis if given intravenously.

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    Attribution Non-Commercial (BY-NC)
    Download as DOC, PDF, TXT or read online from Scribd
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    15K views1 page

    Diazepam (Valium) Drug Study

    Uploaded by

    Emika Dizon
    This document summarizes information about the drug Valium (diazepam). It is used as an adjunct to treat anxiety, for preoperative sedation, and conscious sedation. It works by potentiating the inhibitory neurotransmitter GABA in the central nervous system. Side effects include dizziness, drowsiness, respiratory depression, and dependence with prolonged high dose use. When administering diazepam, vital signs should be monitored and the injection site checked for phlebitis if given intravenously.

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    Generic Name (Brand Name) Generic Name: Diazepam Brand Name: Valium Indication for the Patient: Adjunct

    in the management of: 1) Anxiety 2) Preoperative sedation 3) Conscious sedation - Provides light anesthesia and anterograde amnesia - Treatment of status epilepticus/ uncontrolled seizures - Skeletal muscle relaxant - Management of the symptoms of alcohol withdrawal Classification: Antianxiety agents, anticonvulsants, sedative/hyptonics, skeletal muscle relaxants

    Route/ Dosage Route: IM Dosage: 10mg Frequency: As needed

    Mechanism of Action - Depress the CNS, probably by potentiating GABA, an inhibitory neurotransmitter. - Produces skeletal muscle relaxation by inhibiting spinal polysynaptic afferent pathways. - Has anticonvul-sant properties due to enhanced presynaptic inhibition.Therapeutic effects: (1) Relief of Anxiety (2) Sedation (3) Amnesia (4) Skeletal muscle relaxant (5) Decreased seizure activity

    Side Effects/Adverse Effects - CNS: 1) dizziness 2) drowsiness 3) lethargy 4) hangover 5) headache 6) depression - EENT: 1) blurred vision - RESP: 1) respiratory depression - CV: 1) hypotension - GI: 1) constipation 2) diarrhea 3) nausea 4) vomiting - DERM: 1) rashes - LOCAL: 1) pain (IM) 2) phlebitis (IV) 3) venous thrombosis - MISC: 1) physical & psychological dependence 2)tolerance

    Nursing Considerations - Monitor BP, PR,RR prior to periodically throughout therapy and frequently during IV therapy. - Assess IV site frequently during administration, diazepam may cause phlebitis and venous thrombosis. - Prolonged high-dose therapy may lead to psychological or physical dependence. Restrict amount of drug available to patient. Observe depressed patients closely for suicidal tendencies. - Observe and record intensity, duration and location of seizure activity. The initial dose of diazepam offers seizure control for 15-20 min after administration. - IM injections are painful and erratically absorbed. If IM route is used, inject deeply into deltoid muscle for maximum absorption. - Caution patient to avoid taking alcohol or other CNS depressants concurrently with this medication. - Effectiveness of therapy can be demonstrated by decrease anxiety level; control of seizures; decreased tremulousness.

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