Name Babesiosis (Piroplasmosis) 1. Babesia Microti 2. Babesia Divergens African Trypanosomiasis (Sleeping Sickness) 1. 4r panoso!a brucei ga!biense 2. 4r panoso!

a brucei r0odesiense American Trpanos. (Chagas Disease) 4r panoso!a 2ruzi Malaria &las!odiu! -ivax &. Malariae &. ovale &. 'alciparu! &. 7no8lesi Filariasis 1. =uc0ereria bancro(ti 2. Burgia Mala i >. Burgia ti!ori Onchocerciasis (ri er blin!ness) ?nc0ocerca volvulus

Vector (Infecting stage) 1. Ixodes Scapularis (Sporozites) Ixodes Ricinus (sporozites) 1. )lossina &alpalis (!etac clic) 2. )lossina Morsitans( Metac clic)

Signs Spleen: as !pto!atic. "splenic: #e!ol tic ane!ia$ %&latelets$ Renal 'ailure$ "RDS$ #e!oglobinuria$ oragan (ailure 20ancre 'ever ,eurological s !pto!s *nlarge!ent o( posterior cervical triangle l !p0 nodes$ spleen.

R0odnius &rolixus (!etac clic) "nop0eles Balabacenis (saba0) ". ga!biae ("(rica) ". latens 9 ". cracens (Sara8a7) :Sporozoites; 1. 2ulex 3uin3ue(asciatus 2. Mansonia spp 9 "nop0eles spp(+>) Si!uliu! da!nosu! (blac7(lies)(+>)

Ro!ana6s Sign$ 2ardio! opat0 $ -entricle Dilatation$ Megaoesop0agus$ Megacolon 'ever S8eat0ing stages$ #eadac0e$ <oint "c0es Severe anae!ia$ Renal 'ailure$ &ul!oar oede!a$ <aundice$ Spleno!egal $ *lep0antitis 'ever$ Malaise$ =eig0t loss =0eezing In(la!!ator (=olbac0ia) Itc0iness S7in depig!entation + !p0adenitis *lep0antiasis o( genitals Blindness (=olbac0ia)

Diagnosis )ie!sa Stain *+IS" I!!unoblot I, -ivo .enodiagnosis 4rpanoso!es in c0ancre$ blood$ 2S' or l !p0 node aspirate .enodiagnosis In -itro culture 2I"44 ("g) Branc0ed D," 2"44 ("b) 4r po!astiogotes in blood In -itro &arasite in blood "g capture assa Detection o( Speci(ic 0ost i!!une response )ie!sa stained blood (il!s &2R 2linical s !pto!s Micro(ilaria or &arasites seen 0istologicall Spec(ic "b or "g detected &resence o( ?nc0ocerco!as or !icro(ilariae

Treatment 1. /uinine sulp0ate 1 2linda! cin p0osp0ate 2. "tova3uone 1 "zit0ro! cin Be(ore 2,S:5 1. &enta!idine iset0ionate 2. Sura!in "(ter 2,S 1. *(lornit0ine 2. Melarsopal Benznidazole ,i(urti!ox

"ll &las!odiu! except (alciparu!:5 20loro3uine 'alciparu!: "rtesunate 1 a!odia3uine /uinine 1 2linda! cin (pregnac ) 20e!oprop0 laxis: Malarone Diet0 l5carba!azine citrate "lbendazole Iver!ectin Dox c cline

Iver!ectin Dox c cline