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17. A60-year-old man with no history of bleeding problems has coagulation testing prior to coronary artery bypass grafting. His prothrombin time is 11.5 seconds {INR=1.0), and activated partial thromboplastin time is 160 seconds, Which of the following inflammatory responses is most likely to be abnormal in this patient? ‘A) C5a generation B) Histamine release ) Kallikrein formation 1D) Phagocytosis © E) Platelet aggregation 2. A TOBIEAICArican American woman comes 1 the phys: afi RAVAneHNe SHASERSRSAt back pain She nas worked part ime as a casrier for SVR. anc ‘herasa owincame She as smokes ne-naf pack of loaretes dai for 0 years nd gnks ves cafiotea Beverages daly Her wl ign ae win Perma rete Pysetl evorinton sows tendmesatopalpatonverne sine inne ow back says oe pine sho avenetraconpeessonfactae cf ae cons tomery shows eaeasadibne nealdenst Vics tel se eats pepoaa skaters pabets consent” A Etciy B) Gender ©) Occupation ) Smoking ) Sociooconorie status 25. A 16-year-old boy is brought to the emergency department 30 minutes after he dove into a 3-foot-deep swimming poo! at night. On examination, he is unable to move the right upper and lower extremities. The most likely cause of the movernent deficits in this patient is damage to which of the following labeled regions in the photograph of a cross section of the spinal cord shown? 2. ATTOSPEREBIB wornan foun oe ave RRSIBIERRIEVEE Cespite intravenous broad-spectrum ‘Sutere tray Scns ae idaoong epee ecco ot sNDNMGSIATs x ‘icine each Ver cnocstre'sSMEI'GT 7) Ps earner Shera pesnea a etl vnc caf we pedo cay Sie operon ‘Hoviearoavaleeeg abdomen and wad ener and wih wo as n pace Bod cures and cates afte tp oe eal eater ona fou bre egars sou inte hetyaph A Gram stan foe of he eae shows RGIS cco sthe mos eye eras? A Cana abicans 8) Cojococcus nctoomans C)Eschencha ca D) Serene chanca ©) Stapyococeus aureus ‘46. An investigator is studying bacterial virulence factors. Ferric uptake regulation protein (Fur) binds tightly to DNAa short distance from the 5' end of the genes for these virulence factors. The concentrations of the virulence factors of the bacteria are observed under low-iron and high-iron conditions. Results show that the efficiency of Fur binding increases as the concentration of iron in the culture media increases. Based on these findings, Fur most likely regulates which of, the following processes in these bacteria? ‘A) Methylation © B) Post-transcriptional modification ©) Splicing D) Transcription © E) Translation 3. ABBY o1¢ man comes othe physician because cfMiCURRRARSTTEERER He was invcved in a automobile cbsion tat damages Ns aS) tec nA AREOURENGH ocak ancervertes He's ony abe a ola an hon row physca cal ws pets by hse and be ercton doesnot as along sme. The best exparaion rhs ype of erections a enh 0 whic ote towing? |A) Gentotemerainewes B)bomngunal neves ) Lumbosacral mks Dj Obtuaternerves ) Pedal nerves 30. An 83-year-old man from Puerto Rico is admitted to the hospital because of abdominal pain and blood in his stool for ‘month, He has had an 11-kg (25-Ib) weight loss during this period. The patient speaks little English and is ‘accompanied by his children and extended family. The physician wishes to evaluate the patient for possible colon ceancer, including ordering a colonoscopy. The patient's family requests that he not be told any bad news and that they be allowed to make the decisions about his treatment. Which of the following is the most appropriate next step by the physician? ‘A) Have the family present when the diagnosis is shared with the patient, and allow them to participate in treatment planning B) Inform the family that HIPAA requires that the patient receive this information and make his own decisions regarding his care C) Refer the matter to the hospital's legal counsel to have a power of attomey appointed to a family member D) Respect the wishes of the family and do not share the diagnosis or treatment plan with the patient E) Use a Spanish-speaking interpreter to determine how much the patient wishes to know about diagnosis and treatment 10. A SSFEREEAEN's seme fo noe sal anestesia he sia naede sete BBSaRGH btw con NBLEORELER ‘toma arches, wich ft otowng mustbetavesedtoreac he spinal ana? Ay Aeron ongrcial 8) Costovansverse )Derscuate D)Ligameum Faun )Postenor anginal a Blood Pressure Before Drug Blood Pressure After Drug Drug Administered Injection (mm Hg) Injection (mm Hg) Angiotensin i ‘1070 450/105 Drug X 108/68 122184 ‘Angiotensin Il + drug X 112166 126/06 On three separate occasions, a 25-year-old man is given an injection of angiotensin Il, an injection of drug X, or an Injection of both angiotensin I! and drug X. The table shows his blood pressure (in mm Hg) after each injection. Which of the following best describes drug X? A) Aldosterone receptor antagonist B) Angiotensin II-converting enzyme inhibitor ) Angiotensinogen inhibitor D) Partial agonist at angiotensin Il receptors E) Renin inhibitor n NI oy stro te price tecune tt yea anda t-eek str of ever He has hac ple © caused by Spee ‘Ath he was atthe 50h percertle length ana ne efor weight He doesnot appear Gstested Hs temperate ts AOIOUNIZ 2 F) pase gfe Achos(xray shows 3 Shaner aston Oeetayronal eamraon ‘iaionaloingia Catses cared wa Uencoscoy gov « MAGHDLS/AMEBOSINGIOG Msc Tetotonn sine os mah cal ‘gan? A) Bac antracis 8) Canevaparapsosis ©) Nocata astooiies 1D) Pneumocystis jrovei rmetyP cai) ) Streptococcus gaoyticus emery 8 bovis) 48. A previously healthy 67-year-old woman comes to the physician because of a 3-day history of fever, shortness of breath, nonproductive cough, headache, and muscle pain. Her temperature is 38.9°C (102"F), The lungs are clear to auscultation. Examination shows no other abnormalities. Which of the following vaccines is most lkely to have prevented these findings? A) Diphtheria-tetanus-acellular pertussis © B) Haemophilus influenzae type b C) Hepatitis B D) Inactivated poliovirus E) Influenza virus F) Measies-mumps-rubella G) Typhoid H) 23-Valent pneumococcal 1) Varicetta Anan natn ones scm fal ca 2 es so a SUNS oncentaton ssp ol eral Svs ene aati ance oe stows a Le part undesqoes SNGOEIGGORGEF ve morn utr ho des suds oa ‘Auton whch ofthe flowing rriaoscopicchangesinie prostate resutngtromthe otis fs mos kh eset? ‘A\Compora amviacen 8) Eom Civpemapneccats D) Necrosis fhe blood vessel wats E Scatered sunken cets Fl Weesprese necrosis 34. A9-year-old boy is brought to the physician by his mother because of a 1-year history of cough productive of mucoid sputum, wheezing, and shortness of breath with exertion. He has a history of recurrent upper respiratory tract and sinus infections since birth. He is at the 25th percentile for height and weight. The mother says that his younger sibling is beginning to develop similar problems. Physical examination shows mild clubbing of the fingers. Laboratory studies show markedly increased sweat chloride and sodium concentrations. A defect of which of the following in this patient's bronchial epithelium is most likely causing these symptoms? QA) Adrenoreceptors QB) Membrane receptors OC) Nuclear receptors © D) Protein regulation OE) Protein structure 19. An iESRESRRBUREGENn inside cure hepatocytes la prods detected by WESTER t does not (lange he amour offen gene poducs detectea by NaMBINBAG by “hese esuts suggest ha von increases he Hrequeny of which ofthe fotowng events? ‘A) Maturation athe feb gene ransenet 8) Transcripton ofthe fen gene (C)Transiatonctfernt mRNA ) Transpor etfentin mRNA out oe rcs 20. Two ses of patients (6 of sna RNSIGHTGRIESA AREER sare gen Jon fn Gow X anestesiais tnced by acirnsteing| 8 concearanon 1 ines he ranma aledar conceta fortis aug Gr aisindiced| ng combinabon of sfzane and nous nice, each "he onset ofanosinesia sound abe siaica ‘Golfer n croup Toe ater ecpore ates beteen he ve ups Desexpanedty Gtererces munch te folowng popetes ct sohsare vous ode? A) Blood gas patton cooticort 8) Brain bood parti coeticert (©) Bran.gas parton coeicint Dy Hepatic metabo ©)Lipi soubity Misa abclarconcertraton ©) Mokecuarweicte 25 A ROBB an comes tothe deparient because of a2SHGERSSIRGRSHERSBIN cefrctory to treatment with over-the-counter medications. He Gerard reser BERNGBIRABRBese eye oy meses Wt Serease yp He Became get wen tet ee crt ‘medications should reteve hs symptoms His temperature 8°F) puseSOIminitesprratons Blood pressure SAOMOFTAM Ho Physcalexeriation shows no aarormaltes Which afte flowing {ste most approprate actor by he prySCa? 'A)Deterrine mich crys have been presoibed forthe patient the past £8) Ott srum toiclogy screening on the patent 6). O1dor an MF oft spine _)Presenbeorlya2-wosk couse ofa narcotic modcation rho paint ) Refer the pao toa dug addiction program

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