(Bundle Care)

(Bundle Care)

/ (exit site/tunnel

infections)

25

2(

0.6~6.5/1000

(Gram-positive bacteria)

50~80%

(Staphylococcus aureus)

21~43%

152

 JOURNAL OF KAOHSIUNG MEDICAL ASSOCIATION 2015. vol. 23, No.2

(methicillin-resistant S.aureus,

MRSA) 12~38%

(biofilm)

MRSA

(Candida)

(Pseudomonas

3~44%

aeruginosa)

6~27%

(bundle care)

(extraluminal)

(intraluminal)

)Peter

Pronovost2003

Keystone ICU project

/(catheter hub/cap)

2% chlorhexidine

153

(Bundle Care)

(central vein stenosis)

66%18

1500

2006

(zero

tolerance)

(1)

17

(2)

(3)

2 % chlorhexidine

(4)

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