Faculty of Pharmaceutical Sciences

Chulalongkorn University

FACULTY OF PHARMACEUTICAL SCIENCES

CHULALONGKORN UNIVERSITY
Department | Members | Research and Publication
Members:
Kittisak Likhitwitayawuid
(Prof. Dr.)
Wanchai De-Eknamkul
(Assoc. Prof. Dr.)
Surattana Amnuoypol
(Assoc. Prof. Dr.)
Rutt Suttisri
(Assoc. Prof. Dr.)
Suchada Sukrong
(Assoc. Prof. Dr.)
Boonchoo Sritularak
(Assoc. Prof. Dr.)
Surapong Kengtong
(Assist. Prof.)
Vichien Jongbunprasert
(Assist. Prof.)
Witchuda Thanakijcharoenpath
(Assist. Prof. Dr.)
Taksina Chuanasa
(Assist. Prof. Dr.)
Khanit Suwanborirux
(Dr.)
Waranyoo Phoolcharoen
(Dr.)
Sornkanok Vimolmangkang
(Dr.)
Supakarn Chamni
(Dr.)

Department of
Pharmacognosy and
Pharmaceutical Botany
The Department of Pharmacognosy and
Pharmaceutical Botany has a long history of academic
excellence and strong reputation in preparing
graduates for research in the field of chemistry and
biotechnology in natural products. Prior to the
merging in 2008, the Department was known as two
separate Departments of Pharmacognosy and
Pharmaceutical Botany. Currently, apart from teaching
over 300 undergraduate pharmacy students each year,
the Depar tment offers graduate programs in
Pharmaconosy and Pharmaceutical Botany, leading to
the degrees of Doctor of Philosophy (Ph.D.) and
Master of Science (M.Sc.).

Department of Pharmacognosy and Pharmaceutical Botany

Faculty of Pharmaceutical Sciences

Major Research Areas

Bioactive compounds from
plants and marine organisms

Chulalongkorn University
The Department boasts top-ranked graduate
programs in natural products and herbal medicine in
Thailand. During the past 50 years, we have produced
a number of highly qualified researchers and scientists
to serve in government agencies, academic institution
and research organizations. Today, our alumni span all
ages and all parts of the nation. Our former students
have been successful in a wide range of chosen careers
in both the government and the private sectors.
Se veral of them ha ve been national l y and/or
internationally recognized as scholars and leaders in
the field of natural products.

Computational-aided drug
design and semi-synthesis
Biosynthesis and biotechnology of bioactive secondary
metabolites
Medicinal plant identification
by molecular biological
techniques
Plant-based vaccine research

Since most of our research projects are

extremely funded, our Ph.D. students are usually
oered financial supports in the form of teaching or
research assistantships, in addition to tuition fees.

Department of Pharmacognosy and Pharmaceutical Botany

Faculty of Pharmaceutical Sciences

Chulalongkorn University

Publication
Boonyarikpunchai W, Sukrong S and Towiwat P (2014) Antinociceptive and anti-inflammatory eects of rosmarinic acid isolated from
Thunbergia laurifolia Lindl. Pharmacology Biochemistry and Behavior 124:67-73.
Chaotham C, Pongrakhananon V, Sritularak B and Chanvorachote P (2014) A Bibenzyl from Dendrobium ellipsophyllum inhibits epithelialto-mesenchymal transition and sensitizes lung cancer cells to anoikis. Anticancer research 34:1931-1938.
Charoenrungruang S, Chanvorachote P, Sritularak B and Pongrakhananon V (2014) Gigantol, a bibenzyl from Dendrobium draconis, inhibits
the migratory behavior of non-small cell lung cancer cells. Journal of Natural Products 77:1359-1366.
Charoenrungruang S, Chanvorachote P, Sritularak B and Pongrakhananon V (2014) Gigantol-induced apoptosis in lung cancer cell through
mitochondrial-dependent pathway. Thai Journal of Pharmaceutical Sciences 38:67-73.
Jain R and De-Eknamkul W (2014) Potential targets in the discovery of new hair growth promoters for androgenic alopecia. Expert Opinion
on Therapeutic Targets 18:787-806.
Jain R, Monthakantirat O, Tengamnuay P and De-Eknamkul W (2014) Avicequinone C isolated from Avicennia marina exhibits 5 reductaseType 1 inhibitory activity using an androgenic alopecia relevant cell-based assay system. Molecules 19:6809-6821.
Kimura S, Pangkruang W, Yokoya M, Honda A, Puthongking P, Suwanborirux K and Saito N (2014) Isolation, structure characterization, and
synthesis of stabilized 1,2,3,4-tetrahydroisoquinoline marine natural product from potassium cyanide pretreated Thai tunicate, Ecteinascidia
thurstoni. Heterocycles 88:363-375.
Komaikul J, Kitisripanya T, Tanaka H, Sritularak B and Putalun W (2014) Development of an Enzyme-Linked Immunosorbent Assay for
Specific Detection of Mulberroside A in Mulberry (Morus alba L.) Using Anti-mulberroside A Polyclonal Antibody. Food Analytical Methods
7:58-63.
Kongduang D, De-Eknamkul W, Sitthithaworn W and Wungsintaweekul J (2014) Terpenoid content and transcription profile analysis in
callus and suspension cultures of Croton stellatopilosus. Journal of Plant Biochemistry and Biotechnology 23:61-68.
Phongsopitanun W, Suwanborirux K and Tanasupawat S (2014) Identification and antimicrobial activity of Streptomyces strains from Thai
mangrove sediment. Thai Journal of Pharmaceutical Sciences 38:49-56.
Phongsopitanun W, Thawai C, Suwanborirux K, Kudo T, Ohkuma M and Tanasupawat S (2014) Streptomyces chumphonensis sp. nov.,
isolated from marine sediments. International Journal of Systematic and Evolutionary Microbiology 64:2605-2610.
Promden W, Monthakantirat O, Umehara K, Noguchi H and De-Eknamkul W (2014) Structure and antioxidant activity relationships of
isoflavonoids from Dalbergia parviflora. Molecules 19:2226-2237.
Sawasdee K, Chaowasku T, Lipipun V, Dufat TH, Michel S, Jongbunprasert V and Likhitwitayawuid K (2014) Geranylated homogentisic acid
derivatives and flavonols from Miliusa umpangensis. Biochemical Systematics and Ecology 54:179-181.
Sintupachee S, Ngamrojanavanich N, Sitthithaworn W and De-Eknamkul W (2014) Molecular cloning, bacterial expression and functional
characterisation of cytochrome P450 monooxygenase, CYP97C27, and NADPH-cytochrome P450 reductase, CPR I, from Croton
stellatopilosus Ohba. Plant Science 229:131-141.
Sukphan P, Sritularak B, Mekboonsonglarp W, Lipipun V and Likhitwitayawuid K (2014) Chemical constituents of Dendrobium venustum
and their antimalarial and anti-herpetic properties. Natural Product Communications 9:825-827.
Suwanchaikasem P, Chaichantipyuth C and Sukrong S (2014) Antioxidant-guided isolation of rosmarinic acid, a major constituent from
Thunbergia laurifolia, and its use as a bioactive marker for standardization. Chiang Mai Journal of Science 41:117-127.
Temeeyasen G, Srijangwad A, Tripipat T, Tipsombatboon P, Piriyapongsa J, Phoolcharoen W, Chuanasa T, Tantituvanont A and Nilubol D
(2014) Genetic diversity of ORF3 and spike genes of porcine epidemic diarrhea virus in Thailand. Infection, Genetics and Evolution
21:205-213.
Vimolmangkang S, Somkhanngoen C and Sukrong S (2014) Potential pharmaceutical uses of the isolated compounds from silkworm excreta.
Chiang Mai Journal of Science 41:97-104.
Vimolmangkang S, Zheng D, Han Y, Khan MA, Soria-Guerra RE and Korban SS (2014) Transcriptome analysis of the exocarp of apple fruit
identifies light-induced genes involved in red color pigmentation. Gene 534:78-87.

Department of Pharmacognosy and Pharmaceutical Botany

Faculty of Pharmaceutical Sciences

Chulalongkorn University

Wiriyakarun S, Zhu S, Komatsu K and Sukrong S (2014) The use of cycleave PCR for the dierentiation of the rejuvenating herb species
Pueraria candollei (White Kwao Khruea), Butea superba (Red Kwao Khruea), and Mucuna macrocarpa (Black Kwao Khruea), and the
simultaneous detection of multiple DNA targets in a DNA admixture. Natural Product Communications 9:111-117.
Chamni S and De-Eknamkul W (2013) Recent progress and challenges in the discovery of new neuraminidase inhibitors. Expert Opinion on
Therapeutic Patents 23:409-423.
Chanvorachote P, Kowitdamrong A, Ruanghirun T, Sritularak B, Mungmee C and Likhitwitayawuid K (2013) Anti-metastatic activities of
bibenzyls from Dendrobium pulchellum. Natural Product Communications 8:115-118.
Chaotham C, Chivapat S, Chaikitwattana A and De-Eknamkul W (2013) Acute and chronic oral toxicity of a partially purified plaunotol
extract from Croton stellatopilosus Ohba. BioMed Research International 2013.
Chaotham C, De-Eknamkul W and Chanvorachote P (2013) Protective eect of plaunotol against doxorubicin-induced renal cell death.
Journal of Natural Medicines 67:311-319.
Cheun-Arom T, Chanvorachote P, Sirimangkalakitti N, Chuanasa T, Saito N, Abe I and Suwanborirux K (2013) Replacement of a quinone by
a 5- O -Acetylhydroquinone abolishes the accidental necrosis inducing eect while preserving the apoptosis-inducing eect of renieramycin
M on lung cancer cells. Journal of Natural Products 76:1468-1474.
Dunkoksung W, Vardhanabhuti N, Amnuoypol S and Jianmongkol S (2013) Interaction between P-glycoprotein and Thai herbs with antidiabetic potential. Thai Journal of Pharmaceutical Sciences 38:99-102.
Ketpitthaya S, Sukrong S, Muangsiri W, Vardhanabhuti N, Kao WJ, Sutanthavibul N and Wattanaarsakit P (2013) Preliminary study of spray
drying and freeze drying processes on physicochemical properties of encapsulated rosmarinic acid. Thai Journal of Pharmaceutical Sciences
38:251-254.
Kowitdamrong A, Chanvorachote P, Sritularak B and Pongrakhananon V (2013) Moscatilin inhibits lung cancer cell motility and invasion via
suppression of endogenous reactive oxygen species. BioMed Research International 2013.
Lowtangkitcharoen W, Chuanasa T, Saito N and Suwanborirux K (2013) Preparation of 2'-N-2,3,4-trifluorobenzoyl derivative of cytotoxic
ecteinascidin 770 from the thai tunicate Ecteinascidia thurstoni. Thai Journal of Pharmaceutical Sciences 38:8-11.
Mungmee C, Sitthigool S, Buakeaw A and Suttisri R (2013) A new biphenyl and other constituents from the wood of Garcinia
schomburgkiana. Natural Product Research 27:1949-1955.
Ngankaranatikarn P, Chuanasa T, Sriubolmas N and Suwanborirux K (2013) Antileukemic activity and secondary metabolites of an
endophytic fungus Phomopsis sp. from Artemisia annua. Thai Journal of Pharmaceutical Sciences 38:37-40.
Nualkaew N, Guennewich N, Springob K, Klamrak A, De-Eknamkul W and Kutchan TM (2013) Molecular cloning and catalytic activity of a
membrane-bound prenyl diphosphate phosphatase from Croton stellatopilosus Ohba. Phytochemistry 91:140-147.
Phaopongthai J, Wiyakrutta S, Meksuriyen D, Sriubolmas N and Suwanborirux K (2013) Azole-synergistic anti-candidal activity of altenusin,
a biphenyl metabolite of the endophytic fungus Alternaria alternata isolated from Terminalia chebula Retz. Journal of Microbiology
51:821-828.
Phoolcharoen W, Sooampon S, Sritularak B, Likhitwitayawuid K, Kuvatanasuchati J and Pavasant P (2013) Anti-periodontal pathogen and
anti-inflammatory activities of oxyresveratrol. Natural Product Communications 8:613-616.
Phoolcharoen W and Sukrong S (2013) Molecular analysis of Vitex species using candidate DNA barcoding and PCR-RFLP of the matK gene
for authentication of Vitex glabrata. Natural Product Communications 8:125-128.
Plaibua K, Pongrakhananon V, Chunhacha P, Sritularak B and Chanvorachote P (2013) Eects of artonin e on migration and invasion
capabilities of human lung cancer cells. Anticancer Research 33:3079-3088.
Powan P, Saito N, Suwanborirux K and Chanvorachote P (2013) Ecteinascidin 770, a tetrahydroisoquinoline alkaloid, sensitizes human lung
cancer cells to anoikis. Anticancer Research 33:505-512.
Rattanapisit K, Bhoo SH, Hahn TR, Mason HS and Phoolcharoen W (2013) Rapid transient expression of cholera toxin B subunit (CTB) in
Nicotiana benthamiana. In Vitro Cellular and Developmental Biology - Plant 49:107-113.
Sawasdee K, Chaowasku T, Lipipun V, Dufat TH, Michel S and Likhitwitayawuid K (2013) New neolignans and a lignan from Miliusa
fragrans, and their anti-herpetic and cytotoxic activities. Tetrahedron Letters 54:4259-4263.

Department of Pharmacognosy and Pharmaceutical Botany

Faculty of Pharmaceutical Sciences

Chulalongkorn University

Sawasdee K, Chaowasku T, Lipipun V, Dufat TH, Michel S and Likhitwitayawuid K (2013) Neolignans from leaves of Miliusa mollis.
Fitoterapia 85:49-56.
Somwong P, Suttisri R and Buakeaw A (2013) New sesquiterpenes and phenolic compound from Ficus foveolata. Fitoterapia 85:1-7.
Sooampon S, Phoolcharoen W and Pavasant P (2013) Thermal stimulation of TRPV1 up-regulates TNF-alpha expression in human
periodontal ligament cells. Archives of Oral Biology 58:887-895.
Sripairoj P, Suwanborirux K and Tanasupawat S (2013) Characterization and antimicrobial activity of Amycolatopsis strains isolated from thai
soils. Journal of Applied Pharmaceutical Science 3:11-16.
Sripreechasak P, Matsumoto A, Suwanborirux K, Inahashi Y, Shiomi K, Tanasupawat S and Takahashi Y (2013) Streptomyces siamensis sp.
nov., and Streptomyces similanensis sp. nov., isolated from Thai soils. Journal of Antibiotics 66:633-640.
Sripreechasak P, Tanasupawat S, Matsumoto A, Inahashi Y, Suwanborirux K and Takahashi Y (2013) Identification and antimicrobial activity
of actinobacteria from soils in southern Thailand. Tropical Biomedicine 30:46-55.
Sripreechasak P, Tanasupawat S, Suwanborirux K, Inahashi Y, Matsumoto A, Shiomi K and Takahashi Y (2013) Nonomuraea thailandensis sp.
nov. isolated from Thai soil. Journal of Antibiotics 66:79-84.
Sritularak B, Boonplod N, Lipipun V and Likhitwitayawuid K (2013) Chemical constituents of Canarium subulatum and their anti-herpetic
and DPPH free radical scavenging properties. Records of Natural Products 7:129-132.
Sritularak B, Tantrakarnsakul K, Lipipun V and Likhitwitayawuid K (2013) Flavonoids with anti-HSV activity from the root bark of
artocarpus lakoocha. Natural Product Communications 8:1079-1080.
Supong K, Suriyachadkun C, Pittayakhajonwut P, Suwanborirux K and Thawai C (2013) Micromonospora spongicola sp. nov., an
actinomycete isolated from a marine sponge in the Gulf of Thailand. Journal of Antibiotics 66:505-509.
Supong K, Suriyachadkun C, Suwanborirux K, Pittayakhajonwut P and Thawai C (2013) Verrucosispora andamanensis sp. nov., isolated from
a marine sponge. International Journal of Systematic and Evolutionary Microbiology 63:3970-3974.
Supong K, Suriyachadkun C, Tanasupawat S, Suwanborirux K, Pittayakhajonwut P, Kudo T and Thawai C (2013) Micromonospora
sediminicola sp. nov., isolated from marine sediment. International Journal of Systematic and Evolutionary Microbiology 63:570-575.
Suwanchaikasem P, Phadungcharoen T and Sukrong S (2013) Authentication of the Thai medicinal plants sharing the same common name
'Rang Chuet': Thunbergia laurifolia, Crotalaria spectabilis, and Curcuma a. amada by combined techniques of TLC, PCR-RFLP
fingerprints, and antioxidant activities. ScienceAsia 39:124-133.
Tassanawat P, Putalun W, Yusakul G, Sritularak B, Juengwatanatrakul T and Tanaka H (2013) Production of polyclonal antibody against
madecassoside and development of immunoassay methods for analysis of triterpene glycosides in Centella asiatica. Phytochemical Analysis
24:256-262.
Theanphong O, Thanakijcharoenpath W, Ruangrungsi N, Palanuvej C and Rungsihirunrat K (2013) Phylogenetic relationships of selected
kaempferia plants in thailand based on RAPD marker. Research Journal of Pharmaceutical, Biological and Chemical Sciences 4:1362-1369.
Vimolmangkang S, Han Y, Wei G and Korban SS (2013) An apple MYB transcription factor, MdMYB3, is involved in regulation of
anthocyanin biosynthesis and flower development. BMC Plant Biology 13.
Waropastrakul D, Suwanborirux K, De-Eknamkul W and Chuanasa T (2013) Detection of esterase activity converting cytotoxic renieramycin
M to Jorunnamycin a in the crude enzyme of the Nudibranch Jorunna funebris. Thai Journal of Pharmaceutical Sciences 38:41-44.
Wiriyakarun S, Yodpetch W, Komatsu K, Zhu S, Ruangrungsi N and Sukrong S (2013) Discrimination of the Thai rejuvenating herbs Pueraria
candollei (White Kwao Khruea), Butea superba (Red Kwao Khruea), and Mucuna collettii (Black Kwao Khruea) using PCR-RFLP. Journal of
Natural Medicines 67:562-570.
Boonsom T, Waranuch N, Ingkaninan K, Denduangboripant J and Sukrong S (2012) Molecular analysis of the genus Asparagus based on
matK sequences and its application to identify A. racemosus, a medicinally phytoestrogenic species. Fitoterapia 83:947-953.
Jitvaropas R, Saenthaweesuk S, Somparn N, Thuppia A, Sireeratawong S and Phoolcharoen W (2012) Antioxidant, antimicrobial and wound
healing activities of Boesenbergia rotunda. Natural Product Communications 7:909-912.

Department of Pharmacognosy and Pharmaceutical Botany

Faculty of Pharmaceutical Sciences

Chulalongkorn University

Kongkamnerd J, Cappelletti L, Prandi A, Seneci P, Rungrotmongkol T, Jongaroonngamsang N, Rojsitthisak P, Frecer V, Milani A, Cattoli G,
Terregino C, Capua I, Beneduce L, Gallotta A, Pengo P, Fassina G, Miertus S and De-Eknamkul W (2012) Synthesis and in vitro study of
novel neuraminidase inhibitors against avian influenza virus. Bioorganic and Medicinal Chemistry 20:2152-2157.
Kongkamnerd J, Milani A, Cattoli G, Terregino C, Capua I, Beneduce L, Gallotta A, Pengo P, Fassina G, Miertus S and De-Eknamkul W
(2012) A screening assay for neuraminidase inhibitors using neuraminidases N1 and N3 from a baculovirus expression system. Journal of
Enzyme Inhibition and Medicinal Chemistry 27:5-11.
Maneechai S, De-Eknamkul W, Umehara K, Noguchi H and Likhitwitayawuid K (2012) Flavonoid and stilbenoid production in callus
cultures of Artocarpus lakoocha. Phytochemistry 81:42-49.
Mungmee C, Sitthigool S, Suttisri R and Buakeaw A (2012) Xanthones and biphenyls from Garcinia schomburgkiana wood and their
cytotoxicity. Thai Journal of Pharmaceutical Sciences 36:6-9.
Nualkaew N, Morita H, Shimokawa Y, Kinjo K, Kushiro T, De-Eknamkul W, Ebizuka Y and Abe I (2012) Benzophenone synthase from
Garcinia mangostana L. pericarps. Phytochemistry 77:60-69.
Phechrmeekha T, Sritularak B and Likhitwitayawuid K (2012) New phenolic compounds from Dendrobium capillipes and Dendrobium
secundum. Journal of Asian Natural Products Research 14:748-754.
Phoolcharoen N, Nilgate S, Rattanapuntamanee O, Limpongsanurak S and Chaithongwongwatthana S (2012) A randomized controlled trial
comparing ceftriaxone with cefazolin for antibiotic prophylaxis in abdominal hysterectomy. International Journal of Gynecology and
Obstetrics 119:11-13.
Phoolcharoen W, Sooampon S, Sritularak B, Likhitvitayawuid K, Kuvatanasuchati J and Pavasant P (2012) Anti-periodontal bacterial activity
of oxyresveratrol. Thai Journal of Pharmaceutical Sciences 36:92-94.
Sangmalee S, Laorpaksa A and Sukrong S (2012) A topoisomerase II poison screen of ethnomedicinal Thai plants using a yeast cell-based
assay. Journal of Ethnopharmacology 142:432-437.
Sasivimolphan P, Lipipun V, Ritthidej G, Chitphet K, Yoshida Y, Daikoku T, Sritularak B, Likhitwitayawuid K, Pramyothin P, Hattori M and
Shiraki K (2012) Microemulsion-based oxyresveratrol for topical treatment of herpes simplex virus (HSV) infection: Physicochemical
properties and ecacy in cutaneous HSV-1 infection in mice. AAPS PharmSciTech 13:1266-1275.
Sritularak B, Juengwatanatrakul T, Putalun W, Tanaka H and Morimoto S (2012) A rapid one-step immunochromatographic assay for the
detection of asiaticoside. Journal of Natural Medicines 66:279-283.
Sukrong S, Yun KY, Stadler P, Kumar C, Facciuolo T, Moatt BA and Falcone DL (2012) Improved growth and stress tolerance in the
arabidopsis oxt1 mutant triggered by altered adenine metabolism. Molecular Plant 5:1310-1332.
Supong K, Thawai C, Suwanborirux K, Choowong W, Supothina S and Pittayakhajonwut P (2012) Antimalarial and antitubercular Cglycosylated benz[]anthraquinones from the marine-derived Streptomyces sp. BCC45596. Phytochemistry Letters 5:651-656.
Tabunoki H, Saito N, Suwanborirux K, Charupant K and Satoh JI (2012) Molecular network profiling of U373MG human glioblastoma cells
following induction of apoptosis by novel marine-derived anti-cancer 1,2,3,4-tetrahydroisoquinoline alkaloids. Cancer Cell International 12.
Tassanawat P, Putalun W, Komaikul J, Sritularak B, Juengwatanatrakul T and Tanaka H (2012) Development of Anti-Asiaticoside Polyclonal
Antibody-Based Immunoassay and Applications for Centella asiatica Products and Human Serum. Food Analytical Methods 5:1320-1327.
Tatsukawa M, Punzalan LLC, Magpantay HDS, Villaseor IM, Concepcion GP, Suwanborirux K, Yokoya M and Saito N (2012) Chemistry
of renieramycins. Part 13: Isolation and structure of stabilized renieramycin type derivatives, renieramycins W-Y, from Philippine blue
sponge Xestospongia sp., pretreated with potassium cyanide. Tetrahedron 68:7422-7428.
Wangteeraprasert R, Lipipun V, Gunaratnam M, Neidle S, Gibbons S and Likhitwitayawuid K (2012) Bioactive compounds from Carissa
spinarum. Phytotherapy Research 26:1496-1499.
Wongpankam E, Chunhacha P, Pongrakhananon V, Sritularak B and Chanvorachote P (2012) Artonin E mediates MCL1 down-regulation and
sensitizes lung cancer cells to anoikis. Anticancer Research 32:5343-5351.
Zhou JB, Li XQ, De-Eknamkul W, Suraporn S and Xu JP (2012) Identification of a new Bombyx mori nucleopolyhedrovirus and analysis of
its bro gene family. Virus Genes 44:539-547.

Department of Pharmacognosy and Pharmaceutical Botany

Faculty of Pharmaceutical Sciences

Chulalongkorn University

Changwichit K, Khorana N, Suwanborirux K, Waranuch N, Limpeanchob N, Wisuitiprot W, Suphrom N and Ingkaninan K (2011) Bisindole
alkaloids and secoiridoids from Alstonia macrophylla Wall. ex G. Don. Fitoterapia 82:798-804.
Chatsumpun M, Chuanasa T, Sritularak B and Likhitwitayawuid K (2011) Oxyresveratrol protects against DNA damage induced by
photosensitized riboflavin. Natural Product Communications 6:41-44.
Chayarop K, Peungvicha P, Wongkrajang Y, Chuakul W, Amnuoypol S and Temsiririrkkul R (2011) Pharmaconostic and phytochemical
investigations of Pseuderanthemum palatiterum (Nees) Radlk. ex Lindau leaves. Pharmacognosy Journal 3:18-23.
De-Eknamkul W, Umehara K, Monthakantirat O, Toth R, Frecer V, Knapic L, Braiuca P, Noguchi H and Miertus S (2011) QSAR study of
natural estrogen-like isoflavonoids and diphenolics from Thai medicinal plants. Journal of Molecular Graphics and Modelling 29:784-794.
Halim H, Chunhacha P, Suwanborirux K and Chanvorachote P (2011) Anticancer and antimetastatic activities of renieramyein M, a marine
tetrahydroisoquinoline alkaloid, in human non-small cell lung cancer cells. Anticancer Research 31:193-201.
Juengwatanatrakul T, Sritularak B, Amornnopparattanakul P, Tassanawat P, Putalun W, Tanaka H and Morimoto S (2011) Preparation of a
specific monoclonal antibody to asiaticoside for the development of an enzyme-linked immunosorbent assay. Analyst 136:1013-1017.
Kongkamnerd J, Milani A, Cattoli G, Terregino C, Capua I, Beneduce L, Gallotta A, Pengo P, Fassina G, Monthakantirat O, Umehara K, DeEknamkul W and Miertus S (2011) The quenching eect of flavonoids on 4-methylumbelliferone, a potential pitfall in fluorimetric
neuraminidase inhibition assays. Journal of Biomolecular Screening 16:755-764.
Lipipun V, Sasivimolphan P, Yoshida Y, Daikoku T, Sritularak B, Ritthidej G, Likhitwitayawuid K, Pramyothin P, Hattori M and Shiraki K
(2011) Topical cream-based oxyresveratrol in the treatment of cutaneous HSV-1 infection in mice. Antiviral Research 91:154-160.
Paudel MK, Putalun W, Sritularak B, Morinaga O, Shoyama Y, Tanaka H and Morimoto S (2011) Development of a combined technique
using a rapid one-step immunochromatographic assay and indirect competitive ELISA for the rapid detection of baicalin. Analytica Chimica
Acta 701:189-193.
Pedpradab P and Suwanborirux K (2011) A new acyclic thiophene sesterterpene from the Sikao Bay sponge, Xestospongia sp. Journal of
Asian Natural Products Research 13:879-883.
Phongmaykin J, Kumamoto T, Ishikawa T, Saifah E and Suttisri R (2011) Biologically active constituents of Aglaia erythrosperma. Natural
Product Research 25:1621-1628.
Rinthong PO, Zhu S, Komatsu K, Chanama S and De-Eknamkul W (2011) Genetic variation of Croton stellatopilosus Ohba based on noncoding DNA sequences of ITS, trnK and trnL-F regions. Journal of Natural Medicines 65:641-645.
Saito N, Yoshino M, Charupant K and Suwanborirux K (2011) Chemistry of renieramycins. part 10: Structure of renieramycin v, a novel
renieramycin marine natural product having a sterol ether at C-14 Position. Heterocycles 84:309-314.
Sakee U, Maneerat S, Cushnie TPT and De-Eknamkul W (2011) Antimicrobial activity of Blumea balsamifera (Lin.) DC. extracts and
essential oil. Natural Product Research 25:1849-1856.
Saktrakulkla P, Toriumi S, Tsujimoto M, Patarapanich C, Suwanborirux K and Saito N (2011) Chemistry of ecteinascidins. Part 3: Preparation
of 2-N-acyl derivatives of ecteinascidin 770 and evaluation of cytotoxicity. Bioorganic and Medicinal Chemistry 19:4421-4436.
Sirirak T, Intaraksa N, Kaewsuwan S, Yuenyongsawad S, Suwanborirux K and Plubrukarn A (2011) Intracolonial allocation of trisoxazole
macrolides in the sponge pachastrissa nux. Chemistry and Biodiversity 8:2238-2246.
Sirirak T, Kittiwisut S, Janma C, Yuenyongsawad S, Suwanborirux K and Plubrukarn A (2011) Kabiramides J and K, trisoxazole macrolides
from the sponge Pachastrissa nux. Journal of Natural Products 74:1288-1292.
Somwong P, Suttisri R and Buakeaw A (2011) A new 1,3-diketofriedelane triterpene from Salacia verrucosa. Fitoterapia 82:1047-1051.
Songsumanus A, Tanasupawat S, Thawai C, Suwanborirux K and Kudo T (2011) Micromonospora humi sp. nov., isolated from peat swamp
forest soil. International Journal of Systematic and Evolutionary Microbiology 61:1176-1181.
Sritularak B, Anuwat M and Likhitwitayawuid K (2011) A new phenanthrenequinone from Dendrobium draconis. Journal of Asian Natural
Products Research 13:251-255.
Sritularak B, Duangrak N and Likhitwitayawuid K (2011) A new bibenzyl from Dendrobium secundum. Zeitschrift fur Naturforschung Section C Journal of Biosciences 66 C:205-208.

Department of Pharmacognosy and Pharmaceutical Botany

Faculty of Pharmaceutical Sciences

Chulalongkorn University

Sucontphunt A, De-Eknamkul W, Nimmannit U, Dan Dimitrijevich S and Gracy RW (2011) Protection of HT22 neuronal cells against
glutamate toxicity mediated by the antioxidant activity of Pueraria candollei var. mirifica extracts. Journal of Natural Medicines 65:1-8.
Temkitthawon P, Hinds TR, Beavo JA, Viyoch J, Suwanborirux K, Pongamornkul W, Sawasdee P and Ingkaninan K (2011) Kaempferia
parviflora, a plant used in traditional medicine to enhance sexual performance contains large amounts of low anity PDE5 inhibitors.
Journal of Ethnopharmacology 137:1437-1441.
Thawai C, Tanasupawat S, Suwanborirux K and Kudo T (2011) Agromyces tropicus sp. nov., isolated from soil. International Journal of
Systematic and Evolutionary Microbiology 61:605-609.
Thitikornpong W, Phadungcharoen T and Sukrong S (2011) Pharmacognostic evaluations of lagerstroemia speciosa leaves. Journal of
Medicinal Plants Research 5:1330-1337.
Viraporn V, Yamazaki M, Saito K, Denduangboripant J, Chayamarit K, Chuanasa T and Sukrong S (2011) Correlation of camptothecinproducing aRelationship in the genus ophiorrhiza. Planta Medica 77:759-764.
Ya-ut P, Chareonsap P and Sukrong S (2011) Micropropagation and hairy root culture of Ophiorrhiza alata Craib for camptothecin
production. Biotechnology Letters 33:2519-2526.
Aftab N, Likhitwitayawuid K and Vieira A (2010) Comparative antioxidant activities and synergism of resveratrol and oxyresveratrol.
Natural Product Research 24:1726-1733.
Kantha T, Chaiyasut C, Kantachote D, Sukrong S and Muangprom A (2010) Selection of photosynthetic bacteria producing 5- aminolevulinic
acid from soil of organic saline paddy fields from the Northeast region of Thailand. African Journal of Microbiology Research 4:1848-1855.
Manissorn J, Sukrong S, Ruangrungsi N and Mizukami H (2010) Molecular phylogenetic analysis of Phyllanthus species in Thailand and the
application of polymerase chain reaction-restriction fragment length polymorphism for Phyllanthus amarus identification. Biological and
Pharmaceutical Bulletin 33:1723-1727.
Matsui K, Wirotesangthong M, Thanakijcharoenpath W, Mungmee C and Nishikawa A (2010) Inhibitory eects of scheera leucantha
extract on production of allergic mediators by langerhans cells and mast cells. Journal of Investigational Allergology and Clinical
Immunology 20:463-468.
Naowaratwattana W, De-Eknamkul W and De Mejia EG (2010) Phenolic-containing organic extracts of mulberry (Morus alba L.) leaves
inhibit HepG2 hepatoma cells through G2/M phase arrest and inhibition of topoisomerase II-alpha activity. Journal of Medicinal Food
13:1045-1056.
Sawasdee K, Chaowasku T and Likhitwitayawuid K (2010) New neolignans and a phenylpropanoid glycoside from twigs of miliusa mollis.
Molecules 15:639-648.
Sitthithaworn W, Wungsintaweekul J, Sirisuntipong T, Charoonratana T, Ebizuka Y and De-Eknamkul W (2010) Cloning and expression of 1deoxy-d-xylulose 5-phosphate synthase cDNA from Croton stellatopilosus and expression of 2C-methyl-d-erythritol 4-phosphate synthase
and geranylgeranyl diphosphate synthase, key enzymes of plaunotol biosynthesis. Journal of Plant Physiology 167:292-300.
Sritularak B, Tantituvanont A, Chanvorachote P, Meksawan K, Miyamoto T, Kohno Y and Likhitwitayawuid K (2010) Flavonoids with free
radical scavenging activity and nitric oxide inhibitory eect from the stem bark of Artocarpus gomezianus. Journal of Medicinal Plants
Research 4:387-392.
Sritularak B, Tantrakarnsakul K, Likhitwitayawuid K and Lipipun V (2010) New 2-arylbenzofurans from the root bark of Artocarpus
lakoocha. Molecules 15:6548-6558.
Thawai C, Tanasupawat S, Suwanborirux K and Kudo T (2010) Actinaurispora siamensis gen. nov., sp. nov., a new member of the family
Micromonosporaceae. International Journal of Systematic and Evolutionary Microbiology 60:1660-1666.
Thengyai S, Maitarat P, Hannongbua S, Suwanborirux K and Plubrukarn A (2010) Probing the structural requirements for antitubercular
activity of scalarane derivatives using 2D-QSAR and CoMFA approaches. Monatshefte fur Chemie 141:621-629.
Vangnai AS, Promden W, De-Eknamkul W, Matsushita K and Toyama H (2010) Molecular characterization and heterologous expression of
quinate dehydrogenase gene from Gluconobacter oxydans IFo3244. Biochemistry (Moscow) 75:452-459.
Vimolmangkang S, Sitthithaworn W, Vannavanich D, Keattikunpairoj S and Chittasupho C (2010) Productivity and quality of volatile oil
extracted from Mentha spicata and M. arvensis var. piperascens grown by a hydroponic system using the deep flow technique. Journal of
Natural Medicines 64:31-35.

Department of Pharmacognosy and Pharmaceutical Botany

Faculty of Pharmaceutical Sciences

Chulalongkorn University

Aramwit P, Kanokpanont S, De-Eknamkul W, Kamei K and Srichana T (2009) The eect of sericin with variable amino-acid content from
dierent silk strains on the production of collagen and nitric oxide. Journal of Biomaterials Science, Polymer Edition 20:1295-1306.
Aramwit P, Kanokpanont S, De-Eknamkul W and Srichana T (2009) Monitoring of inflammatory mediators induced by silk sericin. Journal
of Bioscience and Bioengineering 107:556-561.
Charupant K, Daikuhara N, Saito E, Amnuoypol S, Suwanborirux K, Owa T and Saito N (2009) Chemistry of renieramycins. Part 8:
Synthesis and cytotoxicity evaluation of renieramycin M-jorunnamycin A analogues. Bioorganic and Medicinal Chemistry 17:4548-4558.
Charupant K, Suwanborirux K, Daikuhara N, Yokoya M, Ushijima-Sugano R, Kawai T, Owa T and Saito N (2009) Microarray-based
transcriptional profiling of renieramycin M and jorunnamycin C, isolated from Thai marine organisms. Marine Drugs 7:483-494.
Chavanich S, Viyakarn V, Piyatiratitivorakul S, Suwanborirux K and Bussarawit S (2009) Two introduced tunicate species, Ecteinascidia
thurstoni Herdman, 1891 and Clavelina cyclus Tokioka & Nishikawa, 1975, in Thailand. Aquatic Invasions 4:349-351.
Chomcheon P, Wiyakrutta S, Sriubolmas N, Ngamrojanavanich N, Kengtong S, Mahidol C, Ruchirawat S and Kittakoop P (2009) Aromatase
inhibitory, radical scavenging, and antioxidant activities of depsidones and diaryl ethers from the endophytic fungus Corynespora cassiicola
L36. Phytochemistry 70:407-413.
Daikuhara N, Tada Y, Yamaki S, Charupant K, Amnuoypol S, Suwanborirux K and Saito N (2009) Chemistry of renieramycins. Part 7:
Renieramycins T and U, novel renieramycin-ecteinascidin hybrid marine natural products from Thai sponge Xestospongia sp. Tetrahedron
Letters 50:4276-4278.
Deepralard K, Kawanishi K, Moriyasu M, Pengsuparp T and Suttisri R (2009) Flavonoid glycosides from the leaves of Uvaria rufa with
advanced glycation end-products inhibitory activity. Thai Journal of Pharmaceutical Sciences 33:84-90.
Jakmatakul R, Suttisri R and Tengamnuay P (2009) Evaluation of antityrosinase and antioxidant activities of Raphanus sativus root:
Comparison between freeze-dried juice and methanolic extract. Thai Journal of Pharmaceutical Sciences 33:22-30.
Jitsaeng K, De-Eknamkul W and Schneider B (2009) Flavonoids and a new calamenene-type Sesquiterpene from rhizomes of Alpinia
oxymitra K. Schum. (Zingiberaceae). Records of Natural Products 3:110-113.
Maneechai S, Likhitwitayawuid K, Sritularak B, Palanuvej C, Ruangrungsi N and Sirisa-Ard P (2009) Quantitative analysis of oxyresveratrol
content in artocarpus lakoocha and 'Puag-Haad'. Medical Principles and Practice 18:223-227.
Phuwapraisirisan P, Puksasook T, Kokpol U and Suwanborirux K (2009) Corchorusides A and B, new flavonol glycosides as -glucosidase
inhibitors from the leaves of Corchorus olitorius. Tetrahedron Letters 50:5864-5867.
Rangkaew N, Suttisri R, Moriyasu M and Kawanishi K (2009) A new arylnaphthalene lignan from Knema furfuracea. Fitoterapia 80:377-379.
Rangkaew N, Suttisri R, Moriyasu M and Kawanishi K (2009) A new acyclic diterpene acid and bioactive compounds from Knema glauca.
Archives of Pharmacal Research 32:685-692.
Rungrotmongkol T, Frecer V, De-Eknamkul W, Hannongbua S and Miertus S (2009) Design of oseltamivir analogs inhibiting neuraminidase
of avian influenza virus H5N1. Antiviral Research 82:51-58.
Sasivimolphan P, Lipipun V, Likhitwitayawuid K, Takemoto M, Pramyothin P, Hattori M and Shiraki K (2009) Inhibitory activity of
oxyresveratrol on wild-type and drug-resistant varicella-zoster virus replication in vitro. Antiviral Research 84:95-97.
Sritularak B and Likhitwitayawuid K (2009) New bisbibenzyls from Dendrobium falconeri. Helvetica Chimica Acta 92:740-744.
Sritularak B, Morinaga O, Yuan CS, Shoyama Y and Tanaka H (2009) Quantitative analysis of ginsenosides Rb1, Rg1, and Re in American
ginseng berry and flower samples by ELISA using monoclonal antibodies. Journal of Natural Medicines 63:360-363.
Umehara K, Nemoto K, Matsushita A, Terada E, Monthakantirat O, De-Eknamkul W, Miyase T, Warashina T, Degawa M and Noguchi H
(2009) Flavonoids from the heartwood of the Thai medicinal plant Dalbergia parviflora and their eects on estrogenic-responsive human
breast cancer cells. Journal of Natural Products 72:2163-2168.
Wattanapiromsakul C, Chanthathamrongsiri N, Bussarawit S, Yuenyongsawad S, Plubrukarn A and Suwanborirux K (2009) 8Isocyanoamphilecta-11(20),15-diene, a new antimalarial isonitrile diterpene from the sponge Ciocalapata sp. Canadian Journal of Chemistry
87:612-618.

Department of Pharmacognosy and Pharmaceutical Botany