Professional Documents
Culture Documents
I have been posting MCQs regularly for the past 3 years now, on my Facebook page and these MCQs have been well
received by the PG aspirants
These were compiled and printed in the 7th (earlier) edition of "Sure Success MAGIC"; however these have been omitted
from the new 8th edn since I convinced the publisher to make it available online for free download.....so here they are.
SOME of these MCQs have been asked in recent exams like - Dawson fingers and Splendore Hoeppli phenomenon in
DNBCT, Ocriplasmin and burnt rope odour in AIIMS, French paradox in Karnataka CET etc....
For more such MCQs keep in touch with my Facebook page at www.facebook.com/suresuccessramgopal.
JUST RELEASED
MCQs
from
Ramgopal's
Facebook
Page
Read on......
Acute anterior uveitis associated with hypopyon is seen
with this therapy:
a. Zidovudine
b. Maraviroc
c. Reltegravir
d. Rifabutin
D (Rifabutin). Rifabutin is used for prophylaxis of
disseminated MAc infection in AIDS patients; also used in
TB and Crohns. It is well known to be a/w hypopyon
uveitis as a side effect. ALSO NOTE: Cidofovir can also
cause this effect.
All are features of Bourneville's disease except
a. Cardiac rhabdomyoma
b. Konen's fibromas
c. Pancreatic Ca
d. Retinal angiomas
Answer to this morning's qn is "c" (pancreatic Ca). Renal
cell ca is a/w Tuberous sclerosis (Bourneville's) and not
pancreatic ca. Konen's subungual firbomas are also seen.
ALSO NOTE: Retinal astrocytoma (mulberry tumor) is
also seen.
The Pulvinar sign refers to T2 hyperintensity in the
posterior thalamic nuclei (the pulvinar). It is classically
described in
a. Arnold Chiari malformation
b. Parkinson disease
c. Creutzfelt Jakob disease
d. Alzheimer's disease
Answer to this evening's question (pulvinar sign) is "C"
(CJD) as all of you said......actually its in 'variant
CJD' Also NOTE: "Hockey stick sign" in variant CJD :
hyperintense signal involving the pulvinar and
dorsomedial thalamic nuclei bilaterally on FLAIR, which
has the shape of a hockey stick.
A 12-year-old girl with sickle cell disease has pain in her
right arm. An x-ray of the right upper extremity shows
c. Vitamin C
d. Vitamin B12
Answer to this evening's question (HTN) is B (vitamin
D12) Vitamin D deficiency is said to cause hypertension,
the leading factor in heart attacks and stroke. A new study
presented at the annual conference of the European
Society of Human Genetics in Paris recently announced
these findings, stating that there is a causal association
between vitamin D status and blood pression.
Reverse halo sign is seen in all except
a. Blastomycosis
b. Sarcoidosis
c. Cryptogenic organising pneumonia
d. Bronchial asthma
Answer to yestday nights (reverse halo) question is
"D".... The reversed halo sign (also known as the atoll
sign, reverse halo sign, and the fairy ring sign) is defined
by central ground-glass opacity with a surrounding halo
or crescent of consolidation. The reversed halo sign was
first described and is most commonly associated with
COP (cryptogenic organising Pneumonia) but is not
specific to this disease.1 It has been reported in the setting
of
bacterial
pneumonia,
mucormycosis,
paracoccidioidomycosis,
tuberculosis,
sarcoidosis,
radiofrequency ablation, lymphomatoid granulomatosis,
Wegener granulomatosis, tumor, and pulmonary infarcts.
The reversed halo sign is seen in approximately 20% of
patients with COP and 10% of cases of South American
blastomycosis.
The MC cause of Parinauds oculoglandular syndrome is
a. pasteurella multicoda
b. . toxocara canis
c. Leptospira canicola
d. bartonella henslae
ANSWER
to
this
mornings
(parinaud's)
question..... Parinaud's oculoglandular syndrome (POS)
consists of the characteristic granulomatous conjunctival
inflammation, usually unilateral, with extension to or
involvement of local, ipsilateral lymph nodes. Cat-scratch
disease (Bartonella henselae) is by far the most common
etiology.
"Blue diaper syndrome" is due to defect in intestinal
absorption of
a. Vitamin B12
b. Iron
c. Tryptophan
d. Thiamine
Answer to yestday's (blue diaper) question: is C
(tryptophan) Blue Diaper syndrome is a hereditary
metabolic disorder characterised by hypercalcaemia with
ALSO
RED diaper syn-serrratia marcesans, BLACK diaperalkaptonuria
B. bulimia nervosa
C. morbid obsesity
D. AIDS cachexia
answer is bulimia nervosa - russell sign- abrasions and
callus over knuckles can occur in bulimia nervosa due to
inserting hand in mouth for inducing vomiting
Magical thinking is seen in this pers disorder
a . schizoid
b . schizotypal
c . narcissistic
d . antisocial
Answer to this evenings question is schizoTypal disorder
- characterized by: magical Thinking, Other features:
Inappropriate/constricted affect, ideas (not delusions) of
reference, unusual perceptions (e.g. bodily illusions), odd
ideas
(about
telepathy),
suspiciousness,
circumstantial/tangential thinking, eccentricity and excess
social anxiety. More common in relatives of people with
SZ.
Which of the following drugs has been "popped" as an
'orgasm enhancer'
a. Cocaine
b. Marijuana
c. Amyl Nitrite
d. Amphetamines
amyl nitrite as the answer since it has been used as
"poppers" for enhancing orgasms.....{'popping' is the
sound which occurs when the amyl nitrite ampule is
broken/popped}..BUT if u look at other references
cocaine, MDMA (ecstacy), LSD have also been used for
the same purpose............
Patient on which of the following drugs should be
screened for cataract formation ?
a. tamsulosin
b. quetapine
c. Clozapine
d. Olanzapine
Answer to this morn qn is B quetiapine - As per drug
package insert 6 monthly eye checkup needed to rule out
cataract. Dr AU and Dr PBH - topper who wrote their tips
few days earlier mentioned that - dont rush into qm and
reason it out. Tamsulosin causes floppy iris mo doubt
BUT NOT cataracts....u ll come across lotsa elder men
using tamsulosin...for BPH....if it was causing catracts
imagine ....It would have been banned. as for clozapine ,
remember agranulocytosis and weight gain fr olanzapine
Pavithran's nose sign is seen in
a. Acne rosacea
b. Acne vulgaris
A. Adalimumab
B. Infliximab.
C. Ustekinumab
D. Efalizumab
efaliz has been linked with PML n also the fumaric acid
esters r implicated.
CURB score is used for
a. Cannabis addiction
b. Pneumonia
c. Intestinal obstruction
d. Acute pancreatitis
Answer to yestday's qn...... CURB-65 Severity Score for
Community-Acquired Pneumonia: Calculates the CURB65 Score to estimate pneumonia mortality to help
determine
inpatient
vs.
outpatient
treatment. Confusion BUN > 19 mg/dL (7 mmol/L) /
Respiratory Rate 30 / Systolic BP < 90 mmHg or
Diastolic BP 60 mmHg / Age 65
In which type of lung ca is gynecomastia common
a. small cell
b. large cell
c. epidermoid
d. adeno ca
Answer for this morn gynecomastia qn is large cell type of
lung Ca.
Also remember SIADH - Small cell
ca hypercalcemia - Squamous cell ca DIC - Adeno Ca
The most frequently altered gene in estrogen-dependent
endometrioid endometrial carcinoma tumors is
A. p53
B. PTEN
C. kRAS
D. Her2/neu
Answer to yestday night's qn........ Bokhman have
generally categorized endometrial cancer into two broad
groups of tumors using both clinical and histopathological
variables: estrogen-dependent endometrioid endometrial
carcinomas (EECs), or type I, and non-endometrioid
endometrial carcinomas (NEECs), or type II tumors . The
most frequently altered gene in estrogen-dependent
endometrioid endometrial carcinoma tumors is PTEN. In
contrast, p53 mutations or Her2/neu overexpression are
more frequent in non-endometrioid tumors
Egg shell calcification of lymph nodes is seen in all except
a. Silicosis
b. Coal pneumoconiosis
c. Sarcoidosis
d. Leukemia
Answer to this morn qn.........pretty straightforward qn
being asked in various entrances from time
a. Autism
b. Asperger
c. ADHD
d. Rett
a. topical gatifloxacin
b. povidone eyedrops
c. intracameral moxifloxacin
d. oral low dose prednisone for a week
Only proven accepted prophylaxis for postop
endophthalmitis is the instillation of povidone iodine
eyedrops in the conjunctival cul de sac before.
Intracameral moxifolxacin has been used but not
accepted/practciced worldwide.
Labyirynthine A. is MC a branch of
a. basilar A
b . vertebral A
c. antr inf cerebellar A
d. middle cerebral A
Labyrynthine A is a branch of AICA in majority of cases
and only occassionally from basilar A.
Dehisence of anterior wall ox external auditory canal
causes infection in parotid gland via
a. fissure of santorini
b . notch of rivinus
c. petrous fissure
d. retropharyngeal fissure
Anterior wall of extl auditory canal has two fissures /
deficiencies- called as Fissures of santorini through which
parotid or superficial mastoid infection can appear in the
canal and vice versa
Wide habenula perforata can cause problems during
which surgery ?
a. mastoidectomy
b. FESS surgery
c. stapedectomy
d. transphenoidal pituitary surgery
Habenula perforata: the openings thro which branches of
cochlear nerve enter the cochlea; if wide it can leas to
perilymph gusher is stapes surgery;
Verocay bodies maybe found in
a. glomus jugulare
b. acoustic neuroma
c. juvenile nasopharyngeal angiofibroma
d. neuroblastoma
In
schwannoma
(acoustic
neuroma/vestibular
schwannoma), which is benign the more cellular "Antoni
A" pattern with palisading nuclei surrounding pink are
Verocay bodies.
B. laryngeal carcinoma
C. superior nerve palsy
D. vocal cord misuse
nswer to this mornings qn..... Myers and Cotton devised a
classification scheme for grading circumferential
subglottic stenosis from I-IV, which is established
endoscopically and by using noncuffed pediatric
endotracheal tubes of various sizes and sizing the airway.
The scale describes stenosis as a percent of area that is
obstructed. The system contains 4 grades, as
follows: Grade I - Obstruction of 0-50% of the lumen
obstruction Grade II - Obstruction of 51-70% of the
lumen Grade III - Obstruction of 71-99% of the
lumen Grade IV - Obstruction of 100% of the lumen (ie, no
detectable lumen)
Splendore Hoeppli phenomenon is seen in
a. kaposi sarcoma
b. actinomycosis
c. sarcoidosis
d. SLE
Splendore-Hoeppli phenomenon (asteroid bodies) is the
in vivo formation of intensely eosinophilic material
(radiate, star-like, asteroid or club-shaped configurations)
around microorganisms (fungi, bacteria and parasites) or
biologically inert substances. The characteristic formation
of the peribacterial or perifungal Splendore-Hoeppli
reaction probably prevents phagocytosis and intracellular
killing of the insulting agent leading to chronicity of
infection. Infections that can generate Splendore-Hoeppli
reaction: 1. The fungal infections include sporotrichosis,
pityrosporum folliculitis, zygomycosis, candidiasis,
aspergillosis and blastomycosis. 2. The bacterial
infections include botryomycosis, nocardiosis and
ACTINOMYCOSIS. 3. The parasitic conditions include
orbital pythiosis, strongyloidiasis, schistosomiasis and
cutaneous larva migrans. In addition, 4. SplendoreHoeppli reaction may be seen with non-infective
pathology such as hypereosinophilic syndrome and
allergic conjunctival granulomas.
"To study the phenomenon of disease without books is to
sail an uncharted sea, while to study books without
patients is not to go to sea at all."
a. Sir Robert Huthcinson
b. Sir Joseph Lister
c. Sir William Osler
d. Sir Garfield Sobers
William Osler
The risk of acquiring HIV infection from a needlestick
with infected blood is approximately
a. 1:100
10
b. 1:150
c. 1:300
d. 1: 500
Answer to yest nights question Risk of acquiring HIV
from needprick injury from HIV positive person is -- As
per CMDT 2013: 1:300 -- As per 18th harrison = 0.3% = 1:
300 (approx) For mucocutaneous exposure it is 0.09% !
Tropical spastic paraparesis is caused by
a. HIV 1
b. HIV 2
c. HTLV 1
d. HTLV 2
HTLV-I is the cause of two important diseases: -- Adult T
cell leukemia/lymphoma (ATL). and -- tropical spastic
paraparesis, also called HTLV-I-associated myelopathy
(HAM)
Shield cataract is seen in
a. vernal catarrh
b . atopic eczema
c. myotonic dystrophy
d. trauma
hield cataract is in atopic dermatitis Shield ulcer is in
vernal catarrh Trauma - rosette Myotonic dystrophy christmas tree cataract
MC intracranial space occupying lesion in HIV infected
patients is
a. Toxoplasmosis
b. Primary CNS lymphoma
c. Metastases
d. Cryptococcal meningitis
Ans to yest night qn as per CMDT 2013..... MC
intracranial SOL in AIDS is Toxoplasmosis. Second MC is
CNS lymphoma
Bulkeleys membrane is a/w
a. lichen planus
b. psoriasis
c. scabies
d. pemphigus
Bulkeley's membrane: When the scales are completely
scraped off, the stratum mucosum (basement membrane)
is exposed and is seen as a moist red surface (membrane
of Bulkeley)
MC ocular manif of HIV is
a. PORN
b. CMV. retinitis
c. Acute retinal necrosis
d. Cotton wool spots
Cotton wool spots are MC ocular manif of AIDS
infection
in
AIDS
is
11
a. timolol
b. brimonidine
c. betaxolol
d. brinzolamide
Carbonic
anhydrase
inhibitors
(brinzolamide,
dorzolamide) can worsen corneal condition in post
keratoplasty patients and any cases where corneal
endothelium is suspect...
Aprepitant is an
a. antiulcer drug
b. anti craving drug
c. antifungal
d. antiemetic
prepitant is an anti-emetic drug - NK1 receptor anatgonist
used for chemotherapy induced vomiting and postop
vomiting
d. Sciatic N lesion
stains
ANS.........Harrison's 18th......esoph inlet patch..... -Heterotopic gastric mucosa, also known as an esophageal
inlet patch, is a focus of gastric type epithelium in the
proximal cervical esophagus -- The inlet patch is thought
to result from incomplete replacement of embryonic
columnar epithelium with squamous epithelium. -- The
majority of patches are asymptomatic, but acid production
can occur as most contain fundic type gastric epithelium
with parietal cells.
have
significantly
increased
d. efavirenz
ANS.....maraviroc The two major co-receptors for HIV-1
are CCR5 and CXCR4. Maraviroc is effective only against
CCR5 positive viruses and two assays - Trofile assay and
Phenoscript assay are used to find if the patients' virus is
susceptible to maraviroc.
Beck's triad consists of all except
a. hypotension,
b. distended neck veins
c. muffled heart sounds
d. decreased JVP
ANS.........Beck's
triad............3D's -Decreased
BP
(hypotension) -- Distended neck veins (increased JVP) -Distant heart sounds
Ibritumomab tiuxetan been used in
a. Breast cancer
b. Lung cancer
c. Prostate cancer
d. Lymphoma
ANS........NH lymphoma Radiolabelled antibodies are
currently under investigation as a means of delivering
high levels of radiation locally to the tumor bed, thereby
avoiding systemic toxicity. Ibritumomab tiuxetan is
radiolabeled antibody, FDA approved for the treatment of
relapsed low-grade non-Hodgkin lymphoma
Interface dermatitis is a characteristic feature of
a. psoriasis
b lichen planus
c. pemphigus vulgaris
d. impetigo
Ans.....(B).....Lichen Planus.... Interface or lichenoid
dermatitis refers to a pattern of reaction of the skin
characterized by an inflammatory infiltrate that appears to
obscure the dermo-epidermal junction when observed at
low power examination. Lichen planus is the prototype of
interface dermatitis. Here the inflammatory infiltrate hugs
and obscures the DE unction and forms a band-like
pattern in the superficial dermis.
Iris hyperchromia is due to
a. pilocarpine
b. brimonidine
c. brinzolamide
d. bimatoprost
ANS.....Iris hyperchromia....(D) ..Bimatoprost PG analogs
(bimatoprost, latanoprost, travoprost) cause - increase in
length of lashes - Periocular hyperpigmentation - iris
hyperpigmentation - conjunctival congestion
Roflumilast is used in treatment of
a. Bronchial asthma
b. COPD
c. Cystic fibrosis
d. Erectile impotence
ANS...B....COPD Roflumilast
is
a
selective
phosphodiesterase 4 inhibitor indicated as a treatment to
reduce the risk of COPD exacerbations in patients with
severe COPD associated with chronic bronchitis and a
history of exacerbations It is not a bronchodilator and is
not indicated for the relief of acute bronchospasm.
a. suxamethonium
b. vecuronium
c bupivacaine
d. adrenaline
Drugs dosed on ideal body weight (IBW) = vecuronium;
rocuronium, remifentanil - recovery maybe prolonged
when dosed according to total body weight. Suxameth
should be dosed on Total body weight since dosing on
IBW provides inadequate paralysis.
b. hartnup disease
c. phenylketonuria
d. essential fructosuria
ANS.....(B)......Hartnup Hartnup disease is an autosomal
recessive metabolic disorder affecting the absorption of
neutral amino acids (particularly tryptophan that can be,
in turn, converted into serotonin, melatonin and
niacin). Patients present with -- pellagralike skin
eruptions, -- cerebellar ataxia, and -- gross aminoaciduria
Sugammadex
provides
rapid
neuromuscular blockade induced by
A. Atracurium
B. Mivacurium
C. Pancuronium
D. Rocuronium
reversal
from