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There are some amazing and interesting facts about human circulatory system.
2. Each lung contains 300-350 million respiratory units called alveoli making it a total of 700 million
in both lungs.
3. More than half a liter of water per day is lost through breathing.
4. People under 30 years of age take in double the amount of oxygen in comparison to a 80 year
old.
Human beings like other land animals breathe though their nostrils in noses and with the help of lungs. A
pair of lungs are located in the airtight thoracic cavity that is bounded by a convex muscular and elastic
sheet called diaphragm.
Functionally, the lungs are elastic bags resembling rubber balloons. They lack any muscle, which may allow
them to expand or contract by themselves.
In normal breathing, through the nose, air travels through the nasal passages that are lined with ciliated
mucous epithelium. Here, it is cleaned and warmed. Sensory cells detect odours. As air continues through
the pharynx or throat, it crosses the path of food. This is why we can breathe through the mouth. Then, air
passes the epiglottis, enters the larynx or voice box, and goes down the trachea or windpipe. A bronchus
runs to each lung, divides in a tree like manner to give smaller bronchioles and finally deposits the air in the
microscopic thin walled air sacs or alveoli (singular alveolus). A group of alveoli appears like a cluster of
grapes and gives the lungs, a sponge like structure. There are about 150 million alveoli in each lung and
altogether they cover a very large surface area (approximately 70 square metres).
The alveoli are lined by a layer of moist flat epithelial cells and surrounded by networks of blood capillaries.
The blood, which flows to the lungs by pulmonary artery, contains little oxygen and much carbon dioxide.
On the other hand, the air in the alveoli has a high concentration of oxygen and relatively less carbon
dioxide. Thus a 2-way diffusion takes place through the cells of the capillaries. Oxygen enters the blood and
CO2 leaves it. Since enormous breathing surface of lungs is exposed to the external environment the
exchange of gases is computed within a few seconds.
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Fun Trivia : Respiratory System
Structure
Sub-topic of: Human Body Quizzes
Special Topics
The Larynx - Nature's Boom Box What's That Smell? - The Nasal Cavity
Respiratory System
What part of the body is also known as the thoracic cavity? The Respiratory System
What is an examination of the larynx, trachea, and esophagus? The Respiratory System
Infants. RSV is a type of virus the causes cells to mesh rather than remain singular.
In adults, in produces only coldlike symptoms, but children can become extremely ill
with pneumonia, an inflammation of lung tissue.
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Each lung contains 300-350 million respiratory units called alveoli making it a total of 700 million in both
lungs. More than half a liter of water per day is lost through breathing.
We breathe 13 pints of air every minute. People under 30 years of age take in double the amount of oxygen
in comparison to a 80 year old.
• Every minute we breathe, we take in 13 pints of air! That is we breathe about 6.15 liters of air
every minute.
• We breathe about 9 to 20 times every minute. Through every breath, we breathe in about half a
liter of air.
• We inhale and exhale air about 22,000 times per day and in the process, transport about 300
cubic feet of air (which is about 8.5 cubic meters of air)!
• Human breathing mechanism is called tidal breathing, as air comes out the same way it goes in.
• We exhale about half a liter of water vapor in a whole day.
• Breathing is initiated by the diaphragm, which is a stretchable muscle under the lungs. When it
contracts, the volume of the chest cavity rises and the air pressure drops. That is what enables
the high pressure air outside, to enter the lungs and makes them expand like balloons.
• When the diaphragm expands, lungs are emptied of air and we exhale it outside.
• When air
passes
through the
nose and
into the
nasal
passage
called the
windpipe, it
gets filtered,
moistened
and heated.
The Human
Respiratory System
The Pathway
Only in the alveoli does actual gas exchange takes place. There are some 300 million
alveoli in two adult lungs. These provide a surface area of some 160 m2 (almost equal
to the singles area of a tennis court and 80 times the area of our skin!).
Breathing
In mammals, the diaphragm divides the body cavity into the
The inner surface of the thoracic cavity and the outer surface of the lungs are lined
with pleural membranes which adhere to each other. If air is introduced between
them, the adhesion is broken and the natural elasticity of the lung causes it to collapse.
This can occur from trauma. And it is sometimes induced deliberately to allow the
lung to rest. In either case, reinflation occurs as the air is gradually absorbed by the
tissues.
Because of this adhesion, any action that increases the volume of the thoracic
cavity causes the lungs to expand, drawing air into them.
The table shows what happens to the composition of air when it reaches the alveoli.
Some of the oxygen dissolves in the film of moisture covering the epithelium of the
alveoli. From here it diffuses into the blood in a nearby capillary. It enters a red blood
cell and combines with the hemoglobin therein.
At the same time, some of the carbon dioxide in the blood diffuses into the alveoli
from which it can be exhaled.
Atmospheric Air
Component Expired Air (%)
(%)
O2 20.85 15.3
100.0% 100.0%
The rate of cellular respiration (and hence oxygen consumption and carbon dioxide
production) varies with level of activity. Vigorous exercise can increase by 20-25
times the demand of the tissues for oxygen. This is met by increasing the rate and
depth of breathing.
However, the carotid body in the carotid arteries does have receptors that respond to
a drop in oxygen. Their activation is important in situations (e.g., at high altitude in
the unpressurized cabin of an aircraft) where oxygen supply is inadequate but there
has been no increase in the production of CO2.
The smooth muscle in the walls of the bronchioles is very sensitive to the
concentration of carbon dioxide. A rising level of CO2 causes the bronchioles to
dilate. This lowers the resistance in the airways and thus increases the flow of air in
and out.
Asthma
In asthma, periodic constriction of the bronchi and bronchioles makes it more
difficult to breathe in and, especially, out. Attacks of asthma can be
Emphysema
In this disorder, the delicate walls of the alveoli break down, reducing the gas
exchange area of the lungs. The condition develops slowly and is seldom a direct
cause of death. However, the gradual loss of gas exchange area forces the heart to
pump ever-larger volumes of blood to the lungs in order to satisfy the body's needs.
The added strain can lead to heart failure.
Chronic Bronchitis
Any irritant reaching the bronchi and bronchioles will stimulate an increased secretion
of mucus. In chronic bronchitis the air passages become clogged with mucus, and this
leads to a persistent cough. Chronic bronchitis is usually associated with cigarette
smoking.
Irritation of the lungs can lead to asthma, emphysema, and chronic bronchitis. And, in
fact, many people develop two or three of these together. This constellation is known
as chronic obstructive pulmonary disease (COPD).
Cystic fibrosis is a genetic disorder caused by inheriting two defective genes for
the cystic fibrosis transmembrane conductance regulator (CFTR), a transmembrane
protein needed for the transport of Cl−and HCO3− ions through the plasma membrane
of epithelial cells. Defective ion transport in the lung reduces the water content of the
fluid in the lungs making it more viscous and difficult for the ciliated cells to move it
up out of the lungs. Precisely how defective CFTR function produces this effect is still
under investigation. In any case, the accumulation of mucus plugs the airways and
provides a fertile breeding ground for pathogenic fungi and bacteria. All of this
damages the airways — interfering with breathing and causing a persistent cough.
Cystic fibrosis is the most common inherited disease in the U.S. white population.
Lung Cancer
Lung cancer is the most common cancer and the most common cause of cancer deaths
in U.S. males. Although more women develop breast cancer than lung cancer, since
1987 U.S. women have been dying in larger numbers from lung cancer than from
breast cancer.
Lung cancer, like all cancer, is an uncontrolled proliferation of cells. There are several
forms of lung cancer, but the most common (and most rapidly increasing) types are
those involving the epithelial cells lining the bronchi and bronchioles.
Ordinarily, the lining of these airways consists of two layers of cells. Chronic
exposure to irritants