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Respiration. 2002;69(3):280-2.

Respiratory failure due to vocal cord paresis in myasthenia gravis.


Teramoto K, Kuwabara M, Matsubara Y. Source Second Department of Surgery, Shiga University of Medical Science, Seta-Tsukinowa, Otsu, Japan. teramoto@belle.shiga-med.ac.jp

Abstract This report describes a female patient with myasthenia gravis who developed respiratory failure due to vocal cord paresis. The diagnosis was delayed due to the absence of other myasthenic symptoms (e.g. ptosis, muscle weakness and dysphagia). On direct laryngoscopy, her vocal cords were seen to be in the paramedian position and to move apart after the intravenous injection of edrophonium. The patient initially presented with ocular myasthenia and later returned with isolated respiratory failure. A review of the pertinent literature revealed few reports on myasthenia gravis presenting in this manner.
Copyright 2002 S. Karger AG, Basel

http://www.ncbi.nlm.nih.gov/pubmed/12097777

Arch Neurol. 1984 May;41(5):567-8.

Respiratory failure in myasthenia gravis due to vocal cord paresis.


Schmidt-Nowara WW, Marder EJ, Feil PA.

Abstract Paroxysmal dyspnea and stridor in a patient with myasthenia were shown to be due to weakness of vocal cord abductors that improved with anticholinesterase therapy. Despite adequate inspiratory force, breathing was severely impaired by increased inspiratory resistance. The inspiratory flow-volume loop was useful in documenting the laryngeal obstruction and monitoring the effect of therapy. Reinterpretation of previous studies suggests that upper airway obstruction may often contribute to respiratory failure in patients with myasthenia.

http://www.ncbi.nlm.nih.gov/pubmed/6721725

Saint Louis University School of Nursing Level III

A Journal Presented To the Faculty Ms. Christine G. Chan, RN

Vocal cord palsy: An uncommon presenting feature of myasthenia gravis

In Partial Fulfillment For the Course Requirement NCM 1047

Prepared by: Panlaqui, Lester F. Memita, Lichelle R. Purcia, Divine Jane V.

BSN III-C4 January 19, 2012

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