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1-Methyl-2-pyrrolidinone
242799 Anonymous-Anonymous 606-021-00-7 01-2119472430-46-XXXX 872-50-4 Laboratory chemicals, Manufacture of substances
1.2 2. 2.1
Relevant identified uses of the substance or mixture and uses advised against
Identified uses
HAZARDS IDENTIFICATION Classification of the substance or mixture Classification according to Regulation (EC) No 1272/2008 [EU-GHS/CLP]
Eye irritation (Category 2) Skin irritation (Category 2) Reproductive toxicity (Category 1B) Specific target organ toxicity - single exposure (Category 3)
2.2
May cause harm to the unborn child. Irritating to eyes, respiratory system and skin. Avoid exposure - obtain special instructions before use. In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
2.3 3.
3.1
Substances
Synonyms : n-methyl-2-pyrrolidone 1-Methyl-2-pyrrolidone NMP C5H9NO 99,13 g/mol Concentration
: :
N-methyl-2-pyrrolidone Included in the Candidate List of Substances of Very High Concern (SVHC)
according to Regulation (EC) No. 1907/2006 (REACH) CAS-No. 872-50-4 EC-No. 212-828-1 Index-No. 606-021-00-7 Registration number 01-2119472430-46-XXXX -
4. 4.1
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
If swallowed
Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
4.2
4.3 5. 5.1
Further information
Use water spray to cool unopened containers.
ACCIDENTAL RELEASE MEASURES Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapours accumulating to form explosive concentrations. Vapours can accumulate in low areas.
6.2 6.3
Environmental precautions
Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
6.4 7. 7.1
Avoid exposure - obtain special instructions before use.Avoid contact with skin and eyes. Avoid inhalation of vapour or mist. Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic charge.
7.2
7.3
8. 8.1 8.2
EXPOSURE CONTROLS/PERSONAL PROTECTION Control parameters Components with workplace control parameters Exposure controls Appropriate engineering controls
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Immersion protection Material: butyl-rubber Minimum layer thickness: 0,3 mm Break through time: > 480 min Material tested:Butoject? (Anonymous Z677647, Size M) Splash protection Material: Nature latex/chloroprene Minimum layer thickness: 0,6 mm Break through time: > 30 min Material tested:Lapren? (Anonymous Z677558, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 873000, e-mail sales@kcl.de, test method: EN374 If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an Industrial Hygienist familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario.
Body Protection
impervious clothing, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection
Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
9. 9.1
PHYSICAL AND CHEMICAL PROPERTIES Information on basic physical and chemical properties
a) Appearance Form: liquid
b) Odour c) Odour Threshold d) pH e) Melting point/freezing point f) Initial boiling point and boiling range g) Flash point
Colour: colourless no data available no data available 7,7 - 8 Melting point/range: -24 C 202 C81 - 82 C at 13 hPa 91 C - closed cup
h) Evaporation rate no data available i) Flammability (solid, gas) no data available j) Upper/lower flammability or explosive limits k) Vapour pressure l) Vapour density Upper explosion limit: 9,5 %(V) Lower explosion limit: 1,3 %(V) 0,39 - 0,43 hPa at 20 C 1,32 hPa at 40 C 3,42 - (Air = 1.0) 1,028 g/mL at 25 C no data available log Pow: -0,46 no data available no data available no data available no data available no data available 40,7 mN/m
m) Relative density n) Water solubility o) Partition coefficient: noctanol/water p) Autoignition temperature q) Decomposition temperature r) Viscosity s) Explosive properties t) Oxidizing properties
9.2
Skin corrosion/irritation
no data available
Carcinogenicity
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
Damage to fetus possible
Aspiration hazard
no data available
Potential health effects Inhalation May be harmful if inhaled. Causes respiratory tract irritation. Ingestion May be harmful if swallowed. Skin May be harmful if absorbed through skin. Causes skin irritation. Eyes Causes serious eye irritation. Signs and Symptoms of Exposure
prolonged or repeated exposure can cause:, Vomiting, Diarrhoea, Abdominal pain, Rats exposed to 1methyl-2-pyrrolidinone at a concentration of 1 mg/L as an aerosol for 10 days showed depletion of hematopoietic cells in the bone marrow and atrophy of the lymphoid tissues of the thymus, spleen, and lymph nodes.
Additional Information
RTECS: UY5790000
Contaminated packaging
Dispose of as unused product.
ADR/RID: -
IATA: IATA: no
15.
REGULATORY INFORMATION
This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
no data available
16.