SIGNS AND SYMPTOMS OF LUNG CANCER AND TREATMENT 9:02 PM POSTED BY AIN RAHMAN NO COMMENTS Signs and Symptoms

of Lung Cancer and Treatment - Cancer Lungcancer falls into a deadly disease, for both men and women. Compared with other types of cancer, likeprostate cancer, colon cancer, and breast cancer, lung cancer tends to be faster today increased its development. Lung cancer is a form of development is very fast sell (abnormal) in lung tissue caused by the deformation or expansion of the network sell sell itself. If left unchecked this abnormal growth can be spread to other organs, both near and far to the lung such as bone, liver, or brain. Lung cancer caused by smoking more (87%), while the remainder are caused by the substance of asbestos, radiation, arsenic, chromate, nickel, chloromethyl ethers, mustard gas and coke oven emissions can cause lung cancer, although usually only occurs on workers who also smoke. # Classification of Lung Cancer There is a classification of lung cancer, is viewed from both in tissues lung diffusion rate itself or to other organs. But basically the lung cancer disease are divided into two criteria based on the level of distribution: 1. Primary lung cancer Have two main types, namely Small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). SCLC is the kind that sell small pieces (many) which has its very rapid growth to swell. Usually called "oat cell carcinomas" (wheat cell carcinoma). This type is closely associated with smokers, Handling responds well enough through the action of chemotherapy and radiation therapy. While NSCLC is the growth of single cells, but often strike more than one area in the lungs. For example adenoma, hamartoma kondromatous and Sarcoma. 2. Secondary Lung Cancer Lung cancer is a disease that arises as a result of the spread of cancer from other organs, most often breast cancer and colon cancer (stomach). Cancer spreads through the blood, lymphatic system or because of the proximity of the organ. # Signs and Symptoms of Lung Cancer Signs and symptoms of lung cancer will only occur when the development of abnormal cells is more severe towards a more advanced stage, and it takes many years since the beginning of its development. There is even a possibility did not show specific signs and symptoms, but only visible if the X-ray done. But if some of the signs and symptoms below when perceived, should immediately see a doctor: 1. Old coughing in people smoking 2. Difficulty breathing (shortness of breath) 3. Coughing blood (albeit small amounts) 4. Frequent lung infections (pneumonia or bronchitis) 5. The presence of chest pain, shoulder and back section 6. The sound has changed from the usual 7. Cough more than 2 weeks in people who do not smoke 8. Others such as difficulty swallowing, neck and face look swell, decreased appetite, weight loss, tired or weak. # Causes Lung CancerThe biggest cause is smoking, while others are caused by contamination of the surrounding air by the substance of asbestos, air pollution by fumes or combustion including tobacco smoke. There are several cases of diseases that trigger the occurrence of lung cancer diseases, namely tuberculosis and pneumonia. Both of these diseases can cause injury to the lung tissue that supports the organ cells in the growth of abnormal cells inside the cavity. Lung cancer usually develops from this case is the type of adenocarcinoma (adenoma). # Handling and Treatment of Cancer Lung Diseases Handling and treatment or treatment performed on people already diagnosed with lung cancer will depend on the stage is level, the possibility of surgery, as well as the general condition of the patient. This is not apart of history as well as the causes of lung cancer is of course. Providing Nutrition and supplements can reduce symptoms caused by lung cancer. Vitamin D and Fe are very good to be administered by patients with lung cancer, Similarly, http://topworldofhealth.blogspot.com/2011/08/signs-and-symptoms-of-lung-cancer-and.html Squamous http://www.google.com.ph/imgres?q=Squamous+cell+carcinoma+(an+NSCLC)&hl=fil&tbo=d&biw=1517&bih=752&tbm=isch&tbnid=xhNd6sAd8koqM:&imgrefurl=http://www.medicalassessment.com/terms.php%3FR%3D221%26L%3DC&docid=QvuVa0Vp7op9cM&imgurl=http://z.about.com/f/p/440/graphics/images/en/ 18017.jpg&w=400&h=320&ei=Qfj7ULHsGMf_rAfH1oDgDA&zoom=1&iact=hc&vpx=1121&vpy=171&dur=872&hovh=201&hovw=251&tx=115&ty=101&sig=11452951599676037 8713&page=1&tbnh=153&tbnw=191&start=0&ndsp=31&ved=1t:429,r:7,s:0,i:97 adenocarcinoma http://www.google.com.ph/imgres?q=Adenocarcinoma+(an+NSCLC)&num=10&hl=fil&tbo=d&biw=1517&bih=752&tbm=isch&tbnid=7JFM1LqRqZySM:&imgrefurl=http://www.healthcentral.com/copd/h/adenocarcinoma-lungcancer.html&docid=olMDGxjjQKL4CM&imgurl=http://www.healthcentral.com/common/images/1/18014_6742_5.jpg&w=400&h=320&ei=KvT7UJmE87MrQeCoICgAg&zoom=1&iact=hc&vpx=633&vpy=119&dur=386&hovh=187&hovw=234&tx=155&ty=91&sig=114529515996760378713&page=1&tbnh=140&tbnw=175&sta rt=0&ndsp=32&ved=1t:429,r:4,s:0,i:91 large http://www.google.com.ph/imgres?q=Large+cell+cancer+(another+NSCLC)&hl=fil&tbo=d&biw=1517&bih=752&tbm=isch&tbnid=jA8Sj14uylULM:&imgrefurl=http://lungcancer.ucla.edu/adm_lung_cancer_nonsm.html&docid=myE7n54QiQO2rM&imgurl=http://lungcancer.ucla.edu/images/adam_lungcancer_lgcell.jpg& w=400&h=320&ei=mPr7UMSZLM6trAe744CICQ&zoom=1&iact=hc&vpx=196&vpy=129&dur=381&hovh=200&hovw=250&tx=85&ty=92&sig=114529515996760378713&page=1 &tbnh=135&tbnw=168&start=0&ndsp=33&ved=1t:429,r:1,s:0,i:78 Cancer occurs when normal cells undergo a transformation that causes them to grow and multiply without control. The cells form a mass or tumor that differs from the surrounding tissues from which it arises. Tumors are dangerous because they take oxygen, nutrients, and space from healthy cells and because they invade and destroy or reduce the ability of normal tissues to function. Most lung tumors are malignant. This means that they invade and destroy the healthy tissues around them and can spread throughout the body.

The tumors can spread to nearby lymph nodes or through the bloodstream to other organs. This process is called metastasis. When lung cancer metastasizes, the tumor in the lung is called the primary tumor, and the tumors in other parts of the body are called secondary tumors or metastatic tumors. Some tumors in the lung are metastatic from cancers elsewhere in the body. The lungs are a common site for metastasis. If this is the case, the cancer is not considered to be lung cancer. For example, if prostate cancer spreads via the bloodstream to the lungs, it is metastatic prostate cancer (a secondary cancer) in the lung and is not called lung cancer. Lung cancer comprises a group of different types of tumors. Lung cancers usually are divided into two main groups that account for about 95% of all cases. The division into groups is based on the type of cells that make up the cancer. The two main types of lung cancer are characterized by the cell size of the tumor when viewed under the microscope. They are called small cell lung cancer (SCLC) and nonsmall cell lung cancer Don't let the name of this cancer fool you. In this cancer, the small cell can equal big cancer. These small sells multiply very rapidly, resulting in large tumors. It commonly develops in the bronchi of the lungs and spreads. (NSCLC). NSCLC includes several subtypes of tumors. SCLCs are less common, but they grow more quickly and are more likely tometastasize than NSCLCs. Often, SCLCs have already spread to other parts of the body when the cancer is diagnosed. About 5% of lung cancers are of rare cell types, including carcinoid tumor,lymphoma, and others. The specific types of primary lung cancers are as follows: Adenocarcinoma (an NSCLC) is the most common type of lung cancer, making up 30%-40% of all cases. A subtype of adenocarcinoma is called bronchoalveolar cell carcinoma, which creates a pneumonia-like appearance on chest X-rays. Squamous cell carcinoma (an NSCLC) is the second most common type of lung cancer, making up about 30% of all cases. Large cell cancer (another NSCLC) makes up 10% of all cases. SCLC makes up 20% of all cases. Carcinoid tumors account for 1% of all cases. Smoking cigarettes, pipes, or cigars is the most common cause of lung cancer. The earlier in life a person starts smoking, the more often a person smokes, and the more years a person smokes, the greater the risk of lung cancer. If a person has stopped smoking, the risk becomes lower as the years pass.

Anything that increases your chance of getting a disease is called a risk factor. Having a risk factor does not mean that you will get cancer; not having risk factors doesnt mean that you will not get cancer. Talk with your doctor if you think you may be at risk. Risk factors for lung cancer include the following: http://www.emedicinehealth.com/lung_cancer/article_em.htm#lung_cancer_overview Each type of non-small cell lung cancer has different kinds of cancer cells. The cancer cells of each type grow and spread in different ways. The types of non-small cell lung cancer are named for the kinds of cells found in the cancer and how the cells look under a microscope: Squamous cell carcinoma: Cancer that begins in squamous cells, which are thin, flat cells that look like fish scales. This is also called epidermoid carcinoma. Large cell carcinoma: Cancer that may begin in several types of large cells. Adenocarcinoma: Cancer that begins in the cells that line the alveoli and make substances such asmucus.

CAUSES Smoking Smoking is mature in support of 87% of lung cancers overall. Cigar smoking raises the chance as well, as the majority likely does the employment of marijuana. Tobacco smoke contains over 4,000 chemical compounds, many of which have been shown to be cancer-causing or carcinogenic. The two primary carcinogens in tobacco smoke are chemicals known as nitrosamines and polycyclic aromatic hydrocarbons. The risk of developing lung cancer decreases each year following smoking cessation as normal cells grow and replace damaged cells in the lung. In former smokers, the risk of developing lung cancer begins to approach that of a nonsmoker about 15 years after cessation of smoking. - Secondhand Smoke Secondhand smoke is mature in support of roughly 3,000 lung cancer deaths for each day in the United States. Living with someone who smokes raises your chance of increasing lung cancer by 20-30%. Passive smoking or the inhalation of tobacco smoke by nonsmokers who share living or working quarters with smokers, also is an established risk factor for the development of lung cancer. Research has shown that nonsmokers who reside with a smoker have a 24% increase in risk for developing lung cancer when compared with nonsmokers who do not reside with a smoker. An estimated 3,000 lung cancer deaths that occur each year in the U.S. are attributable to passive smoking. - Environmental Causes Environmental causes of lung cancer include exposure to chemicals, wood smoke, and radiation. Taking part in solitary study, air pollution was estimated to be the cause of lung cancer in 5% of men and 3% of women in the United States. - Occupational Causes Occupational causes of lung cancer include exposure to chromium, tar, arsenic, and nickel, amongst other substances. Taking part in the U.S., its estimated with the purpose of 13 to 29% of lung cancers in men are allied to occupational exposures. - Genetics Genetic factors can drama a role in lung cancer, and 1.7% of lung cancers are considered hereditary. An inherited disposition to lung cancer is more collective in women, nonsmokers, and patients under the age of 60 who develop the disease. http://www.medicinenet.com/lung_cancer/page2.htm#what_causes_lung_cancer

Tobacco smoke is the primary cause of lung cancer, being thought to be repsonsible for at least 80 per cent of cases. Although nonsmokers can get lung cancer, the overall risk is about 10 times greater for smokers. The risk increases with the number of cigarettes smoked per day. If you are a heavy smoker consuming more than 20 cigarettes a day, the risk of developing lung cancer rises to about 30 to 40 times higher than if you don't smoke. The main reason for the substantial increase in the disease over the last 50 years has been the increase in the number of people who smoke cigarettes. This has resulted from the industrial production and marketing of tobacco. Read more: http://www.netdoctor.co.uk/diseases/facts/lungcancer.htm#ixzz2IWoeXIFV Follow us: @NetDoctor on Twitter | NetDoctorUK on Facebook ASSESSMENT: Possible signs of non-small cell lung cancer include a cough that doesn't go away and shortness of breath. Sometimes lung cancer does not cause any symptoms and is found during a chest x-ray done for another condition. Symptoms may be caused by lung cancer or by other conditions. Check with your doctor if you have any of the following problems: Chest discomfort or pain. A cough that doesnt go away or gets worse over time. Trouble breathing. Wheezing. Blood in sputum (mucus coughed up from the lungs). Hoarseness. Loss of appetite. Weight loss for no known reason. Feeling very tired. Trouble swallowing. Swelling in the face and/or veins in the neck. Tests that examine the lungs are used to detect (find), diagnose, and stage non-small cell lung cancer.

Tests and procedures to detect, diagnose, and stage non-small cell lung cancer are often done at the same time. Some of the following tests and procedures may be used: Physical exam and history: An exam of the body to check general signs of health, including checking for signs of disease, such as lumps or anything else that seems unusual. A history of the patients health habits, including smoking, and past jobs, illnesses, and treatments will also be taken. Laboratory tests: Medical procedures that test samples of tissue, blood, urine, or other substances in the body. These tests help to diagnose disease, plan and check treatment, or monitor the disease over time. Chest x-ray: An x-ray of the organs and bones inside the chest. An x-ray is a type of energy beam that can go through the body and onto film, making a picture of areas inside the body. Enlarge X-ray of the chest. X-rays are used to take pictures of organs and bones of the chest. X-rays pass through the patient onto film. CT scan (CAT scan): A procedure that makes a series of detailed pictures of areas inside the body, such as the chest, taken from different angles. The pictures are made by a computer linked to an x-ray machine. A dye may be injected into a vein or swallowed to help the organs or tissues show up more clearly. This procedure is also called computed tomography, computerized tomography, or computerized axial tomography. Sputum cytology: A procedure in which a pathologist views a sample of sputum (mucus coughed up from the lungs) under a microscope, to check for cancer cells. D. Procedure B 1. Early morning sputum is to be collected 2. Rinse mouth with plain water 3. Use sterile container 4. Sputum specimen for culture and sensitivity is collected before the first dose of antibiotics 5. For Acid Fast Bacilli (AFB) staining, collect sputum specimen for 2 consecutive mornings (3 specimens).

Fine-needle aspiration (FNA) biopsy of the lung: The removal of tissue or fluid from the lung using a thin needle. A CT scan, ultrasound, or other imaging procedure is used to locate the abnormal tissue or fluid in the lung. A small incision may be made in the skin where the biopsy needle is inserted into the abnormal tissue or fluid. A sample is removed with the needle and sent to the laboratory. A pathologist then views the sample under a microscope to look for cancer cells. A chest x-ray is done after the procedure to make sure no air is leaking from the lung into the chest. Enlarge Lung biopsy. The patient lies on a table that slides through the computed tomography (CT) machine which takes x-ray pictures of the inside of the body. The x-ray pictures help the doctor see where the abnormal tissue is in the lung. A biopsy needle is inserted through the chest wall and into the area of abnormal lung tissue. A small piece of tissue is removed through the needle and checked under the microscope for signs of cancer. Bronchoscopy: A procedure to look inside the trachea and large airways in the lung for abnormal areas. A bronchoscope is inserted through the nose or mouth into the trachea and lungs. A bronchoscope is a thin, tube-like instrument with a light and a lens for viewing. It may also have a tool to remove tissue samples, which are checked under a microscope for signs of cancer. Bronchoscopy. A bronchoscope is inserted through the mouth, trachea, and major bronchi into the lung, to look for abnormal areas. A bronchoscope is a thin, tube-like instrument with a light and a lens for viewing. It may also have a cutting tool. Tissue samples may be taken to be checked under a microscope for signs of disease. Bronchoscopy. A bronchoscope is inserted through the mouth, trachea, and major bronchi into the lung, to look for abnormal areas. A bronchoscope is a thin, tube-like instrument with a light and a lens for viewing. It may also have a cutting tool. Tissue samples may be taken to be checked under a microscope for signs of disease. Thoracoscopy: A surgical procedure to look at the organs inside the chest to check for abnormal areas. An incision (cut) is made between two ribs, and a thoracoscope is inserted into the chest. A thoracoscope is a thin, tube-like instrument with a light and a lens for viewing. It may also have a tool to remove tissue or lymph node samples, which are checked under a microscope for signs of cancer. In some cases, this procedure is used to remove part of the esophagus or lung. If certain tissues, organs, or lymph nodes cant be reached, a thoracotomy may be done. In this procedure, a larger incision is made between the ribs and the chest is opened. Thoracentesis: The removal of fluid from the space between the lining of the chest and the lung, using a needle. A pathologist views the fluid under a microscope to look for cancer cells. http://www.cancer.gov/cancertopics/pdq/treatment/non-small-cell-lung/Patient/page1 NON SURGICAL INTERVENTIONS External beam radiation therapy comes from a machine that aims radiation at your cancer. The machine is large and may be noisy. It does not touch you, but rotates around you, sending radiation to your body from many directions. External beam radiation therapy is a local treatment, meaning that the radiation is aimed only at a specific part of your body. For example, if you have lung cancer, you will get radiation to your chest only and not the rest of your body. Most people get external beam radiation therapy once a day, 5 days a week, Monday through Friday. Treatment lasts for 2 to 10 weeks, depending on the type of cancer you have and the goal of your treatment. The time between your first and last radiation therapy sessions is called a course of treatment. Radiation is sometimes given in smaller doses twice a day (hyperfractionated radiation therapy). Your doctor may prescribe this type of treatment if he or she feels that it will work better. Although side effects may be more severe, there may be fewer late side effects. Doctors are doing research to see which types of cancer are best treated this way. http://www.cancer.gov/cancertopics/coping/radiation-therapy-and-you/page3 http://www.medicalnewstoday.com/info/lung-cancer/#.UP0cVjgUs9E

Quit smoking Smoking is the number one risk factor for lung cancer. It is estimated that 87% of lung cancer deaths are caused by smoking. 2) Listen to Mom, and eat those fruits and veggies! Fruits and vegetables are rich with antioxidants and flavonoids. Antioxidants and flavonoids help protect your cell's DNA and repair damaged cells. 3) Have your home tested for radon. Radon is the result of broken down uranium. It is a radioactive gas that cannot be seen, felt, smelled or tasted. Uranium occurs naturally in the soil, and the fear is that homes are being built over natural deposits, creating high levels of indoor radon exposure, which can lead to lung cancer. 4) Know what you are being exposed to in the workplace. If you are exposed to fumes, dust, and chemicals in the workplace, you have a right to know what you are being exposed to. Talk to your employer about limiting exposure to possible carcinogens. 5) Avoid secondhand smoke. Secondhand smoke contains over 60 known carcinogens. These carcinogens interrupt normal cell development. This interference of cell development is what starts the cancer process.

Avoid carcinogens at work. Take precautions to protect yourself from exposure to toxic chemicals at work. Follow your employer's precautions. For instance, if you're given a face mask for protection, always wear it. Ask your doctor what more you can do to protect yourself at work. Your risk of lung damage from workplace carcinogens increases if you smoke. Eat a diet full of fruits and vegetables. Choose a healthy diet with a variety of fruits and vegetables. Food sources of vitamins and nutrients are best. Avoid taking large doses of vitamins in pill form, as they may be harmful. For instance, researchers hoping

to reduce the risk of lung cancer in heavy smokers gave them beta carotene supplements. Results showed the supplements actually increased the risk of cancer in smokers. Drink alcohol in moderation, if at all. Limit yourself to one drink a day if you're a woman or two drinks a day if you're a man. Anyone age 65 and older should drink no more than one drink a day. Exercise. Aim for at least 150 minutes a week of moderate aerobic activity or 75 minutes a week of vigorous aerobic activity. You can also do a combination of moderate and vigorous activity. Check with your doctor first if you aren't already exercising regularly. Start out slowly and continue adding more activity. Biking, swimming and walking are good choices. Add exercise throughout your day park farther away from work and walk the rest of the way or take the stairs rather than the elevator. Strength training is also important. Try to do strength training exercises at least twice a week.
http://www.mayoclinic.com/health/lung-cancer/DS00038/DSECTION=prevention http://cancer.about.com/od/lungcancer/ss/lungcancerguide_4.htm hypo http://www.unboundmedicine.com/nursingcentral/ub/view/Diseases-and-Disorders/73630/all/hypothyroidism

COLLABORATIVE Most patients are diagnosed and treated on an outpatient basis. The goal of treatment is to return the patient to the euthyroid (normal) state and to prevent complications. The treatment of choice is to provide thyroid hormone supplements to correct hormonal deficiencies. Treatment of the elderly patient is approached more cautiously because of higher risk for cardiac complications and toxic effects. The medication should not be given if the pulse rate is greater than 100. The treatment is considered to be life-long, requiring ongoing medical assessment of thyroid function. Polypharmacy is a significant concern for the hypothyroid patient. Several classifications of drugs are affected by the addition of thyroid supplements, including beta blockers, oral anticoagulants, bronchodilators, digitalis preparations, tricyclic antidepressants, and cholesterol-lowering agents. Because significant cardiovascular disease often accompanies hypothyroidism, the patient is at risk for cardiac complications if the metabolic rate is increased too quickly. Therefore, the patient needs to be monitored for cardiovascular compromise (palpitations, chest pain, shortness of breath, rapid heart rate) during early thyroid therapy. The diet for the hypothyroid patient is generally low in calories, high in fiber, and high in protein. As the metabolic rate rises, the caloric content can be increased. The patient's intolerance to cold may extend to cold foods, making meal planning more difficult. Pharmacologic Highlights Treatment consists of replacing the deficient hormone with synthetic thyroid hormone; low doses are initially used, and the dose is increased every 1 to 2 months based on the clinical response and serial laboratory measurements that show normalization of TSH levels in primary hypothyroidism. The patient begins to experience clinical benefits in 3 to 5 days, which level off after approximately 4 to 6 weeks. After the dose is stabilized, patients can be monitored with laboratory measurement of TSH annually.
http://www.unboundmedicine.com/nursingcentral/ub/view/Diseases-and-Disorders/73630/all/hypothyroidism

The signs and symptoms of hypothyroidism vary, depending on the severity of the hormone deficiency. But in general, any problems you have tend to develop slowly, often over a number of years. At first, you may barely notice the symptoms of hypothyroidism, such as fatigue and weight gain, or you may simply attribute them to getting older. But as your metabolism continues to slow, you may develop more obvious signs and symptoms. Hypothyroidism signs and symptom may include: Fatigue Increased sensitivity to cold Constipation Dry skin

Unexplained weight gain Puffy face Hoarseness Muscle weakness Elevated blood cholesterol level Muscle aches, tenderness and stiffness Pain, stiffness or swelling in your joints Heavier than normal or irregular menstrual periods Thinning hair Slowed heart rate Depression Impaired memory When hypothyroidism isn't treated, signs and symptoms can gradually become more severe. Constant stimulation of your thyroid gland to release more hormones may lead to an enlarged thyroid (goiter). In addition, you may become more forgetful, your thought processes may slow, or you may feel depressed. Advanced hypothyroidism, known as myxedema, is rare, but when it occurs it can be life-threatening. Signs and symptoms include low blood pressure, decreased breathing, decreased body temperature, unresponsiveness and even coma. In extreme cases, myxedema can be fatal. Hypothyroidism in infants Although hypothyroidism most often affects middle-aged and older women, anyone can develop the condition, including infants. Initially, babies born without a thyroid gland or with a gland that doesn't work properly may have few signs and symptoms. When newborns do have problems with hypothyroidism, they may include: Yellowing of the skin and whites of the eyes (jaundice). In most cases, this occurs when a baby's liver can't metabolize a substance called bilirubin, which normally forms when the body recycles old or damaged red blood cells. Frequent choking. A large, protruding tongue. A puffy appearance to the face. As the disease progresses, infants are likely to have trouble feeding and may fail to grow and develop normally. They may also have: Constipation Poor muscle tone Excessive sleepiness

When hypothyroidism in infants isn't treated, even mild cases can lead to severe physical and mental retardation. Hypothyroidism in children and teens In general, children and teens who develop hypothyroidism have the same signs and symptoms as adults do, but they may also experience: Poor growth, resulting in short stature Delayed development of permanent teeth Delayed puberty Poor mental development When to see a doctor See your doctor if you're feeling tired for no reason or have any of the other signs or symptoms of hypothyroidism, such as dry skin, a pale, puffy face, constipation or a hoarse voice. You'll also need to see your doctor for periodic testing of your thyroid function if you've had previous thyroid surgery; treatment with radioactive iodine or anti-thyroid medications; or radiation therapy to your head, neck or upper chest. However, it may take years or even decades before any of these therapies or procedures result in hypothyroidism. If you have high blood cholesterol, talk to your doctor about whether hypothyroidism may be a cause. And if you're receiving hormone therapy for hypothyroidism, schedule follow-up visits as often as your doctor recommends. Initially, it's important to make sure you're receiving the correct dose of medicine. And over time, the dose you need may change.
http://www.mayoclinic.com/health/hypothyroidism/DS00353/DSECTION=symptoms