PATHOLOGY

M.B.B.S DEGREE EXAMINATION-JULY,2012

507-A

22

SECOND M.B.B.S. EXAMINATION

PATHOLOGY (GENERAL PATHOLOGY&HAEMATOLOGY)

TIME :2 HOURES

PAPER-1

MAX.MARKS:40

ANSWER ALL QUESTIONS:

1.A 3 year old child presented with pallor,growth retardation and history of repeated
blood transfusion. The child is having splenomegaly and mild jaundice. Skull x-ray
dhowing Hair on end (crew cut )appeance.
10
a)What is the most probable diagnosis?
b)Describe various laboratoryinvestigations to establish the diagnosis.
c)Discuss pathognesis of the disorder.
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5X4=20

2.Differences between benign and malignant tumours

3.Morphology of lepromatous leprosy
4.Antonuclear antibodies
5.Turner syndrome
6.Phagocytosis
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5X2=10

7.Name four (4)types of Necrosis with examples.

8.Significance of exfoliative cytology
9.Nutmeg liver
10.Name four(4) fat stains.
11.Name the tests for detection of proteins in urine.

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M.B.B.S DEGREE EXAMINATION-JULY,2012

507-B

23

SECOND M.B.B.S. EXAMINATION

PATHOLOGY (SYSTEMIC PATHOLOGY)

TIME :2 HOURES

PAPER-2

MAX.MARKS:40

ANSWER ALL QUESTIONS:

1.A 55year old female presented with post menopausal bleeding and foul smelling 10
vaginal discharge.P/Vexamination revealed unhealthy,indurated and ulcerated cervix
a)What is the provisional diagnosis?
b)How do you establish the diagnosis?
c)Describe the microscopic picture of the lesion.
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5X4=20

2.Crohns disease-morphology
3.Ewings sarcoma
4.Renal cell carcinoma
5Aschoff nodules/bodies
6.Undescended testes.
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5X2=10

7.Pyogenic meningitis-CSF findings.

8.Lung cancer-Histological types
9.Gall stones-Types and complications
10.Name the benign tumours of the breast.
11.Follicular adenoma thyroid-Gross and histological picture.

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M.B.B.S DEGREE EXAMINATION-JANUARY,2013

507-A

24

SECOND M.B.B.S. EXAMINATION

PATHOLOGY (GENERAL PATHOLOGY&HAEMATOLOGY)

TIME :2 HOURES

PAPER-1

MAX.MARKS:40

ANSWER ALL QUESTIONS:

1.An young and stout male met with an accident.He sustained multiple injuries,fractures of femur and
tibia.These fractures are stabilized at Surgery soon after admission.He is in a stable condition.However 2
days after admission he suddenly becomes dyspneic and developed tachypnea and
tachycardia,irritability,restlessness and it progressed to delirium,coma and death on 7 th day.
a)What is the provisional diagnosis?
b)Discuss the pathogenesis of the lesion
c)Describe microscopic picture of the lungs in the above condition.
d)How Frozen sections of the lung tissue help in final diagnosis at autopsy and mention various stains
specific for it ?
1+4+2+3=10
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5X4=20

2.Protein derived mediators of acute inflammation.

3.Down syndrome
4.Pathogenesis of Amyloidosis
5.Physical carcinogenesis
6.Blood and Bone marrow findings in Aplastic anemia.
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5X2=10

7.Mention 4 sequelae of Ghons complex

8.Name 4 main components of Extra cellular Matrix(ECM)
9.Name 4 morphologic changes (cytoplasmic&nuclear) in necrotic cell.
10.Name 4 Blood components separated from whole blood and mention one clinical use for each.
11.Mention 4 morphologic characteristics of a Myeloblast.

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M.B.B.S DEGREE EXAMINATION-JANUARY,2013

507-B

25

SECOND M.B.B.S. EXAMINATION

PATHOLOGY (SYSTEMIC PATHOLOGY)

TIME :2 HOURES

PAPER-2

MAX.MARKS:40

ANSWER ALL QUESTIONS:

1.A 60 years old male having fever and weight loss presented with painless hematuria,flank pain and
palpable mass in the left renal angle.CT Scan confirmed a specific organ mass lesion, regional
lymphnodes and renal vein involvement. Chest radiograph showed pulmonary cannonball secondaries
and his PCV is of 60%.
a)What is the provisional diagnosis?
b)Discuss the etiopathogenesis of the lesion.
c)Describe its morphology.
d)Mention various paraneoplastic syndromes produced by this lesion.

1+3+4+2=10

WRITE SHORT NOTES ON:

5X4=20

2.Etiopathogenesis of Emphysema.
3.Pathology of Graves disease.
4.Describe location and macroscopic appearance of vegetations in Bacterial Endocarditis(BE). Mention
extra cardiac complications of BE.
5.Morphology of common and classic osteosarcoma.
6.Etiologic and moephologic classification of cirrhosis of Liver.
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5X2=10

7.Cause and histology of Barrett esophagus.

8.Name one benign tumor and three premalignant (carcinoma in situ) lesions of penis.
9.Diagrammatically illustrate the two microscopic patterns of fibroadenoma breast.
10.Name 4 surface epithelial tumors of ovary.
11.Mention the site,size,appearance and common complication of berry aneurysm.

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