Professional Documents
Culture Documents
Minireview
Siderophores in environmental research:
roles and applications
E. Ahmed* and S. J. M. Holmstrm
Department of Geological Sciences, Stockholm
University, Stockholm, Sweden.
Summary
Siderophores are organic compounds with low
molecular masses that are produced by microorganisms and plants growing under low iron conditions.
The primary function of these compounds is to
chelate the ferric iron [Fe(III)] from different terrestrial
and aquatic habitats and thereby make it available for
microbial and plant cells. Siderophores have received
much attention in recent years because of their
potential roles and applications in various areas of
environmental research. Their significance in these
applications is because siderophores have the ability
to bind a variety of metals in addition to iron, and
they have a wide range of chemical structures and
specific properties. For instance, siderophores function as biocontrols, biosensors, and bioremediation
and chelation agents, in addition to their important
role in weathering soil minerals and enhancing plant
growth. The aim of this literature review is to outline
and discuss the important roles and functions of
siderophores in different environmental habitats and
emphasize the significant roles that these small
organic molecules could play in applied environmental processes.
Introduction
Iron (Fe) is an essential element for the growth of almost
all living microorganisms because it acts as a catalyst in
enzymatic processes, oxygen metabolism, electron transfer, and DNA and RNA syntheses (Aguado-Santacruz
Received 18 December, 2013; revised 13 January, 2014; accepted
21 January, 2014. *For correspondence. E-mail engy.ahmed@
geo.su.se; Tel. (+46) (0)8674 7725; Fax (+46) (0)8674 7897.
Microbial Biotechnology (2014) 7(3), 196208
doi:10.1111/1751-7915.12117
Funding Information The present article was supported by grants
from The Swedish Research Council for Environment, Agricultural
Sciences and Spatial Planning (FORMAS), Sweden and the Faculty
of Science, Stockholm University, Sweden.
2014 The Authors. Microbial Biotechnology published by John Wiley & Sons Ltd and Society for Applied Microbiology.
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and
reproduction in any medium, provided the original work is properly cited.
2014 The Authors. Microbial Biotechnology published by John Wiley & Sons Ltd and Society for Applied Microbiology, Microbial
Biotechnology, 7, 196208
198
Fig. 1. Representative examples of microbial siderophores and phytosiderophores with the stability constant of each type. Microbial
siderophores consist of four main types. Hydroxamates produced by both bacteria (ferrioxamine B) and fungi (ferrichrome). Catecholate
(enterobactin), carboxylate (rhizobactin) and mixed type (pyoverdine) produced by bacteria. The most common phytosiderophore is mugineic
acid. All the chemical structures were drawn using ChemDraw Standard 13.0 software (PerkinElmer, Waltham, MA, USA).
2014 The Authors. Microbial Biotechnology published by John Wiley & Sons Ltd and Society for Applied Microbiology, Microbial
Biotechnology, 7, 196208
2014 The Authors. Microbial Biotechnology published by John Wiley & Sons Ltd and Society for Applied Microbiology, Microbial
Biotechnology, 7, 196208
200
2014 The Authors. Microbial Biotechnology published by John Wiley & Sons Ltd and Society for Applied Microbiology, Microbial
Biotechnology, 7, 196208
2014 The Authors. Microbial Biotechnology published by John Wiley & Sons Ltd and Society for Applied Microbiology, Microbial
Biotechnology, 7, 196208
202
2014 The Authors. Microbial Biotechnology published by John Wiley & Sons Ltd and Society for Applied Microbiology, Microbial
Biotechnology, 7, 196208
2014 The Authors. Microbial Biotechnology published by John Wiley & Sons Ltd and Society for Applied Microbiology, Microbial
Biotechnology, 7, 196208
204
2014 The Authors. Microbial Biotechnology published by John Wiley & Sons Ltd and Society for Applied Microbiology, Microbial
Biotechnology, 7, 196208
2014 The Authors. Microbial Biotechnology published by John Wiley & Sons Ltd and Society for Applied Microbiology, Microbial
Biotechnology, 7, 196208
206
2014 The Authors. Microbial Biotechnology published by John Wiley & Sons Ltd and Society for Applied Microbiology, Microbial
Biotechnology, 7, 196208
2014 The Authors. Microbial Biotechnology published by John Wiley & Sons Ltd and Society for Applied Microbiology, Microbial
Biotechnology, 7, 196208
208
2014 The Authors. Microbial Biotechnology published by John Wiley & Sons Ltd and Society for Applied Microbiology, Microbial
Biotechnology, 7, 196208