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Flavanones, chalcones and dihydrochalcones nature, occurrence, and dietary burden. J Sci
Food Agric
ARTICLE in JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE MAY 2000
Impact Factor: 1.88 DOI: 10.1002/(SICI)1097-0010(20000515)80:7<1073::AID-JSFA568>3.0.CO;2-B
CITATIONS
106
2 AUTHORS:
Francisco A Toms-Barbern
Mike Clifford
University of Surrey
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Review
Flavanones, chalcones and dihydrochalcones
nature, occurrence and dietary burden
Francisco A Tomas-Barberan1 and Michael N Clifford2*
1
Abstract: This paper reviews the occurrence in foods of avanones, chalcones and dihydrochalcones.
The major dietary sources of avanones and dihydrochalcones are citrus fruits and apples respectively. These compounds may make a greater contribution to the total daily intake of avonoids than
the more extensively studied avonols. There are no data for plasma or tissue levels, but both endogenous and gut ora metabolites of both classes of compound are found in urine. For these reasons,
these compounds deserve greater attention in epidemiological studies.
# 2000 Society of Chemical Industry
Keywords: absorption; apples; beer; burden; chalcones; cider; citrus; dihydrochalcones; eriodictyol; avanones;
avanonols; fruit juices; hesperidin; hops; licorice; metabolism; naringenin; narirutin; neohesperidin; phloretin;
phloridzin; prenylavanones; retrochalcones
INTRODUCTION
* Correspondence to: Michael N Clifford, School of Biological Sciences, University of Surrey, Guildford, Surrey GU2 5XH, UK
(Received 29 October 1999; accepted 10 November 1999)
1073
FA Tomas-Barberan, MN Clifford
Table 1. Flavanones characteristic of common citrus fruits
Flavanone
Eriocitrin
Narirutin
Hesperidin
Naringin
Neohesperidin
Sweet orange
(Citrus sinensis)
Sour orange
(Citrus aurantium)
Lemon
(Citrus limon)
Grapefruit
(Citrus paradisi)
Trace
Trace
Lime
(Citrus aurantifolia)
Mandarin
(Citrus reticulata)
, absent.
, , , present in progressively greater amounts.
Treatment
Hand-squeezed (fresh)
Unpasteurised
Pasteurised
Concentrated (after dilution)
528
191
166
169
42
171
205
179
93
53
45
48
7
47
55
52
FA Tomas-Barberan, MN Clifford
Table 3. Flavanone content of citrus juices
Sweet orange
Valencia
Hand-squeezed
Unpasteurised
Fresh, hand-squeezed, various
cultivars
Unpasteurised
487584
215227
235407
122260
122254
Grand
total
3084
1865
1865
1680
Tomas-Barberan
FA, unpublished
Tomas-Barberan
FA, unpublished
15
6284
15
154239
15
528
Trace
Fresh, hand-squeezed
104537
Brazilian, various cultivars
Frozen concentrate, Brazilian,
531690
after dilution to 12 Brix
Frozen concentrated pulp-wash, 10891200
Brazilian, after dilution to
12 Brix
Lemon
Hand-squeezed
84196
Grapefruit
Hand-squeezed
Various cultivars
80191
4794
33161
23124
97209
Reference
64
64
65
66
67
166226
Hand-squeezed, Navel
Pumelo
Grapefruit pumelo hybrids
Sour orange
Mandarin
Total
bitter
150249
65
113481
73419
295377
40144
65
67
5
67
440495 5001000 69
133362
67
67
Table 4. Content of dihydrochalcones in apple juices and other apple products. Values are mg l1 (juices) or mg kg1 (jams, etc)
Phloretin-2 '-xyloglucoside
Phloridzin
Total DHC
Reference
4.0
2733
3.8
2.12.3
1.7
5.2
0.4
5
34
27
53
17
1438
4.4
1318
5.4
2.73.3
2.3
9.1
1.0
4
38
12
33
12
83196
8.4
4051
9.2
4.85.6
4.0
14.3
1.4
9
72
39
86
29
97223
35
36
70
70
70
70
70
34
34
34
34
34
31
DIETARY BURDEN
FA Tomas-Barberan, MN Clifford
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