Pathogenesis ( Diseases )

Bacteria

Gram -Ve cocci

Pyogenic
Niesseria
meningitides
meningitidis
( headachevomiting- stiff
neck )
Gonorrhoeae
Niesseria
( sexual
gonorrhoea
transmitted) acute
e
conjunctivitis in
infants of mother
with Gonorrhoeae
Gram +Ve cocci
Pneumonia
Staphylococ
impetigo wound
cus aureus
infection
osteomyelitis food
poisoning due to
enterotoxins
Normal flora in 40%

of health people
Sore throat (
tonsillitis,
pharyngitis )
scarlet fever otitis
media impetigo
rhrumatic fever
glomerulonephritis Normal flora in
upper respiratory
tract
Septic abortion
gynecological
sepsis UTI
neonatal septicemia
meningitis
normal flora in
femal genital tract
Lobar pneumonia
bronchitis

Streptococc
us pyogenes
( Group A )

Strepotococ
cus
agalactiae
( Group B )

Strepotococ
cus

meningitis
pneumoniae
conjunctivitis
normal flora in
upper respiratory
tract
Endocarditis- dental Strepotococ
caries
cus
bacteraemia
Viridians
Normal flora in
upper respiratory
tract
UTI biliary tract
Strepotococ
wound- ulcers
cus
endocarditisFecalis
meningitis normal ( Enterococc
flora in vagina &
us )
intestinal tract
( Group D )
Gram Ve Bacilli
UTI wound
E. coli
infection

meningitis
bacteraemia in
neonates - diarrhea
Chest infection
(bronchopneumonia
abscesses ) - UTI
UTI ( Alkaline )
abdominal & wound
infection
1- Enteric fever
( typhoid &
paratyphoid )
2- enterocolitis
3- Bacteraemia
Bacillary dysentery
or shigellosistransmission by
faecal oral route
Plague ( Bubonic

Klebsiella
pneumonia
Proteus
mirabilis

salmonella

Shigella

Yersinia

pneumonic
septicaemic
Transimission : 1infected fleas
(Xenopsylla ) from
rats or domestic
animals
( dogs,cats )
2- inhaling
organisms in
airborn droplets
Opportunistic
hospital acquired
infection
1-skin infection
( burn,
wound,ulcers )
2- UTI ( following
catherization )
3- Respiratory tract

pestis

Pseudomon
as
aeruginosa

infection
4- ear infection
(otitis externa)
5- eye infection
rice water stool
Vibrio
diarrhea
cholera
( enterotoxin
activates adenylate
cyclase within
intestine result in
secretion of large
fluid & electrolytes )
transmission by
faecal oral routes
Brucellosis or
Brucella
undulant fever
( zoonotic disease )
1-pyogenic
Haemophilu
(purulent )
s influenzae

meningitis in young
children below 5
years old
2- pneumonia (adult
)
3- acute epiglottitis
( fatal airway
obstruction )
4- cellulitis
Whooping cough
( infection of
mucosa of upper
respiratory tract )
Enteritis watery
diarrhea or
dysentery
( main source are
unpasteurized milk
fecal oral route )

Bordetella
pertussis

campylobact
er

Chronic gastritis
Helicobacter
lead to ulceration &
pylori
may cause gastric
carcinoma
Abdominal infection Bacteroides
( particularly
fragilis
following surgery )
peritonitis
gynaecological
infections
( puerperal sepsis )lung , cerebral
abscesses soft
tissue infections
Gram +Ve Bacilli
Gas gangrene
Clostridium
( myconecrosis )
perfringens
food poisoning

Tetanus ( lockjaw ) , fatal disease

caused by
neurotoxin
Fatal food poisoning
cause paralysis
( botulism )
Antibiotic
associated diarrhea
( pseudomembrano
us colitis )
Anthrax ( cutaneous
pulmonary
meningoencephaliti
s ) by herbivore as
sheep, cattle, goats

Clostridium
tetani

Clostridium
botulinum
Clostridium
difficile

Bacillus
anthracis

Food poisoning from Bacillus

infected rice &
cereus

other cereals
Diphtheria ( nasal , Corynebacte
nasopharyngeal ,
rium
tonsillar
diphtheriae
diphtheria ) in
young children
odema of neck
grey yellow
membrane , it can
block the passage
of air & cause death
Meningitis &
Listeria
septicemia mainly
monocytoge
in ( neonate ,
nes
pregnant women ,
elderly persons
Spirochetes
Sexual transmitted Treponema
disease cause
pallidium
Syphilis

Yaws disease

Treponema
pertenue
Leptospira
interrogans

Leptospirosis ( Flulike illness ) by

infected animal
urine as dogs
Relapsing fever by Borrelia
louse
recurrentis
Lyme disease by
Borrelia
Tick
burgdrfei
Intracellular bacteria
Eye disease 1Chlamydia
Trachoma 2trachomatis
neonatal
ophthalmia 3conjunctivitis 4Genetal tract
infection ( urethritis
)

Atypical pneumonia Chlamydia

pneumonia
Endemic fever by
Rickettsia
Flea
typhi
Epidemic fever by
Rickettsia
Louse
prowazakeii
Rocky mountain
Rickettsia
spotted fever by
rickettsii
Tick
Q fever
Coxiella
burnettii