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10. area around nucleus = electron shell ( atoms can have more than 1 shell)
C. Molecules and Compounds
1. molecule = atoms joined together by chemical bonds
2. molecule is also the smallest unit of a compound that retains the properties
of the compound.
3. ex: an oxygen molecule = 2 oxygen atoms
4. ex: a carbon dioxide molecule = 1 carbon atom and 2 oxygen atoms
5. ex: salt (sodium chloride) = 1 atom of Na (sodium) and 1 atom of Cl
(chloride)
D. Chemical Reactions
What's the difference between Chemistry and cooking? In Chemistry, you should never
lick the spoon.
1. synthesis reaction
a. a new and more complex molecule is made from multiple, simpler ones.
b. ex: single molecules from the digestive tract (are absorbed) and form
more complex substances.
2. decomposition reaction
a. a single, complex molecule is broken into multiple, simpler ones.
3. exchange reaction
a. certain atoms are exchanged between molecules
b. ex: sodium bicarbonate given for indigestion relief mixes with
stomach acid. NaHCO3 + HCL = NaCl + H2O + CO2
4. chemical reactions either require energy or release energy
5. some reactions require a catalyst.usually special proteins called
enzymes
E. Compounds in Living Organisms
Why did Carbon marry Hydrogen? They bonded well from the minute they met.
1. inorganic compounds
a. NO hydrocarbons ( H or C bonded together)
b. Ex: H2O, salts, acids, bases
c. Essential for life
d. Water
1) universal solvent
2) chemicals added to water called solutes
3) result = a solution
4) hydrophilic = water loving (chemicals mix well with
water)
(measure of acidity)
1. acid = 1.0 (max)
2. base = 14.0 (max)
3. blood and tissues need a pH of 7.4 (critical)
4. stomach acid = 1.0 to 2.5
5. saliva = 9.0 to 11.5
6. metabolic acidosis
a. too much acid in the bloodstream and body
b. cause.can be related to diabetes and too much fat breakdown
c. cause.can be related to kidney problem and cannot excrete acid
F. Proteins
1. made of amino acids (AA)
2. 20 different AA
a. essential = must supplement in diet
b. non-essential = made by the body
3. Functions
a. catalysts for chemical reactions
b. immune system
c. structural framework.bones, tendons, ligaments
d. physical movement
1) actin and myosin are proteins that are filaments which
slide upon each other to cause contraction and shortening
of a muscle. This results in movement of a bone or soft
tissue.
G. Nucleic Acids
1. DNA
a.
b.
c.
2. RNA
a.
b. 5 different nucleotides
4. genes
a. sequence of nucleotides that carries the information to make one
peptide chain.
b. Long chains of genes are combined with proteins to form
chromosomes.
H. Conclusion or Why ?.........Who Cares ??
1. Physiological processes are derived from chemical reactions.
2. Digestion of food, Respiration, Growth, Reproduction and Stimulation of
Nerve Impulses all rely on molecules and chemical reactions.
c. surface specializations
1) cilia
2) keratin
d. transitional epithelial tissue
1) stretches..ex: bladder
e. glandular epithelial tissue
1) endocrine glands
a) glands with ducts or tubules
b) secrete hormones into the bloodstream directly
c) ex: thyroid, adrenal.pancreas is both endocrine & exocrine
2) exocrine glands
a) have ducts to deliver secretions
b) ex: sweat glands, salivary, .and pancreas
B. Connective Tissue
1. Examples..
a. blood
b. tendons
c. ligaments
d. fat
e. cartilage
f. bone
2. Adipose (fat)
a. white adipose = found throughout body
b. brown adipose
1) found in newborns
2) found in animals that hibernate
3) site of heat production
4) high number of mitochondria for heat production causes
dark cytoplasm which causes brown fat.
3. Ligaments
a. connect bone to bone
b. have elastic fibers that allow some stretch
c. massive Nuchal ligament in horses allows them to lower heads
for long times.
4. Tendons = connect muscle to bones
5. Cartilage
a. present in joints to prevent rubbing
b. no nerve tissue, so can tolerate a lot of wear with no pain
c. present in nose, ears, other areas where structure is needed
b. Smooth muscle
1) not consciously controlled.involuntary muscle
2) found in blood vessels, bladder, stomach, intestines
c. Cardiac muscle
1) only found in the heart
2) specialized cells in heart muscle (SA node) supply signal
for heart to beat.
3) Pacemaker can override SA node.
4) Involuntary muscle.no conscious control
5) Also is striated microscopically.
D. Nervous Tissue
1. Receives and transmits electrical and chemical stimuli.
2. Neuron is the basic cell unit.
3. dendrites = extensions of cell that receive impulses
4. axon = long, single extension of neuron that conducts impulses away from
the cell.
E. Tissue Healing and Repair
1. Inflammation
a. area becomes hot, red, swollen and tender
b. bodys attempt to isolate the area
c. steps..
1) vasoconstriction initially to control hemorrhage
2) heparin and histamine are released to area to stimulate
blood flow.which causes redness.
3) Fluid from plasma flows to area causing swelling.
4) Clot formation begins using fibrinogen and platelets.
5) Macrophages (like Pac-Man) clean up debris and
neutrophils arrive to fight infection.
6) Histamine and heparin decrease, causes return to normal.
2. Granulation Tissue
a. pathogens inhibit healing
b. bright, pink tissue called granulation tissue.
c. Too much granulation tissue is called Proud Flesh .
1) common in horses
3. Epithelialization (scar tissue)
a. scab is bridge over both sides of wound to allow healing below.
b. Some flexibility is lost with scar tissue.
c. 1st Intention Healing
1) edges of wound heal without serious granulation or
scarring.
General Notes
1. Largest organ system of body.
2. Covers and protects the entire body.
3. Includes hair, skin, hooves ,horns, claws and skin glands
4. Outer layer are all dead cells.
5. Keratin = tough, protective, protein which allows skin to be waterproof.
6. Skin regulates body temperature.
7. Sensory organ..via touch and pressure.
8. Important in Vit D synthesis.
9. Thickness of skin varies with species and location on body
a. ex: Rhino vs. mosquito
b. ex: Giraffe skin is 1-2 inches thick.
10. 2 layers of skin
a. epidermis = composed of keratinized cells which form waterproof
schield. It is avasculari.e. no blood vessels.
b. Dermis = deeper layer made of tough, fibroelastic tissue which contains
blood vessels.
c. SQ = subcutaneous.which is below the dermis and is mostly adipose
tissue. Majority of animal injections are given SQ.
B Epidermis
1. Most cells are keratinocytes.which produce keratin.
2. Constant shedding of dead keratinocytes is called keratinization.
3. Pigment in skin is caused by melanocyted
a. controlled by MSH (melanocyte stimulating hormone) from the brain
2.
3.
4.
5.
6.
5) comminuted fracture
a) bone is broken into several pieces
6) compression fracture
a) broken bone produced when bones are pressed
together
7) transverse fracture = broken across the bone
8) oblique fracture = broken at an angle
9) spiral fracture = break is twisted or spiraled apart
7. Bone Shapes
a. long bones
1) diaphysis
2) proximal and distal epiphyses
b. short bones
1) squares or cubes
2) ex: carpal or tarsal bones
3) provide strength and some mobility
c. flat bones
1) thin & flat
2) ex: scapula, pelvic bones, skull bones
d. irregular bones
1) ex: vertebrae
2) sesamoid bones
a) named because shaped like a sesame seed.
b) In some tendons over surface of joints
c) Patella (knee cap) is the largest
8. Bone Marrow
a. in hollow medullary cavity of bone
b. red bone marrow = hematopoietic (makes RBCs)
c. yellow bone marrow
1) mainly adipose (fat)
2) most common type in adult animals
3) does not produce RBCs
9. Articular Surfaces
a. Where bones come together to form joints.
b. Covered by a smooth surface of hyaline cartilage (called articular
cartilage).
c. Reduces friction and wear on bones.
d. Terms
1) condyle = large, round articular surface at distal end of
humerus and femur.
2) Head = round, articular surface on proximal end of a long
bone. Ex: femoral head or humeral head.
3) Neck = shaft portion attaching head to body of long bone.
B. Axial Skeleton
1. Skull
a. 37 or 38 separate bones
b. Joined by immoveable joints called sutures .
c. Mandible (lower jaw) is connected by a moveable , synovial
joint.
d. Occipital bone = a single bone that forms the base of the skull.
1) where spinal cord exits the skull (hole is called the
foramen magnum)
2) connects to 1st vertebra called the atlas.
e. temporal bones
1) form the lateral walls of cranium and contain the middle
and inner ear.
a) external acoustic meatus
b) bony canal that leads to middle ear.
2) Form the temporomandibular joint (TMJ)
f. frontal bones
1) create the forehead of the skull.
2) Contains frontal sinus.hollow structure that
communicates to horns if present.
3) Cornual process of the frontal bone is core of horn
g. internal bones of the cranium
1) sphenoid bone
a) houses the pituitary gland
2) ethmoid bone
a) has a cribiform plate related to sense of smell
(olfactory bulb)
h. bones of the middle ear (ossicles..tiny bones)
1)
2)
3)
4)
malleus = hammer
incus = anvil
stapes = stirrup
they transmit vibrations from the tympanic membrane (ear
drum) to the cochlea, which has receptor cells.
i. External bones of the face
1) incisive bones.house incisor teeth
2) nasal bones.make up dorsum of nose
3) maxillary bones
a) upper jaw
b) house upper teeth
c) has maxillary sinus
d) palantine bone (hard palate)
4) lacrimal bones..form medial portion of orbit.
5) Zygomatic bonesform protection for the eye with the
zygomatic arch.
6) Mandible.lower jaw
a) houses lower teeth
b) only moveable skull bone
c) forms TMJ
d) 2 bones join together in front by mandibular
symphysis
e) Weakest part and can easily separate upon force.
f) No symphysis in pigs and horses..one fused bone.
g) Shaft is horizontal portion of mandible
h) Ramus is vertical portion of mandible.
j. Internal bones of the face
1) palantine bones.hard palate
2) pterygoid bonessmall bones that support the pharynx
3) vomer bone .single bone on midline that forms
nasal septum (separation of left and right nasal passages
4) turbinates .thin, scroll-like bones which fill nasal
cavity
k. Hyoid bone..U-shaped structure that supports tongue
2. Spinal Column (vertebral column)..5 Regions
a. cervicalusually 7 vertebrae
b. thoracic...12 to 18 depending on species
c. lumbar5 to 7 depending on species
d. sacral ..3 to 5
e. coccygeal 5 to 23 depending on species
f. spinous processes vary with each region
g. vertebral formulae.
1) cat = C 7, T 13, L 7, S 3, Cy 5 -23
b. Distal end has large condyle (knob) which forms the stifle joint
or true knee.
4. Patella.knee cap
a. largest sesamoid bone
b. within the large distal tendon of the quadriceps muscle which
inserts on the tibial crest .
c. patellar luxations in dogs vs. horses
5. Fabellae
a. 2 small sesamoids behind the femoral condyles
b. Not present in horses and cattle
6. Tibia
a.
b.
c.
d.
7. Fibula
a.
b.
c.
8. Tarsal Bones
a. same as ankle in humans or hock in animals
b. 2 rows of bones
9. Metatarsal Bones..similar to metacarpal bones
a. make up bones of our feet in humans
10. Phalanges
Miscellaneous Bones
A. Os penis.bone in the penis
1. dogs, raccoons, beavers, ferrets, walruses
2. creates urinary problems if crystals or stones are present.
B. Os rostri.bone in the nose of pigs
1. allows them to root into tough areas
C. Os cordis ..
1. bone within the heart of cattle and sheep
2. helps support the valves of the heart
Muscular System
A. One of 4 basic tissues in the body
1. Muscles only contract.
2. Must have a nerve stimulus to contract skeletal muscle.
3. Cardiac and smooth muscle have built in nerve stimulus.
4. Over 100 muscles in the body.
5. Muscles generally have an origin and insertion.
6. Contraction results in movement..Kinesiology is the study of muscle
movement.
7. Tendons attach muscles to bones.
8. Aponeurosis is where a flat muscle attaches.
9. Linea alba is the aponeurosis where the abdominal muscles meet ventrally.
a. white line is what the linea alba is referred to, and the site to do surgery.
B. Three muscle types
1. Skeletal muscle..voluntarywe can control to some extent.
a. looks striated under the microscope
b. most activities operate on cruise control.such as walking, breathing,
routine things that our body has learned to do automatically,
2. Cardiac muscle .involuntary
3. Smooth muscle..involuntary
a. GI tract, blood vessels, eyes, bladder
C.Muscle Names
a. by action..flexors, extensors, abductors, adductors
b. by shape..Deltoid (triangular).in the shoulder
c. by direction of fibersoblique, transverse, straight (rectus)