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A B S T R A C I
Objectives. A major component
of the increasing trend in cesarean
sections in Western Australia is the
rise in emergency cesarean sections
in primiparous women. The aim of
this study was to identify independent risk factors (particularly those
known early in pregnancy) associated with operative delivery in lowrisk primiparous women.
Methods. Retrospective multivariate lo^stic regression analyses of
antenatal and perinatal data were
conducted for all low-risk primiparous women entering labor spontaneously and giving birth in Western
Australia in 1987 (n = 3641).
Reisults. Of the subjects, 58%
had a spontaneous vaginal delivery,
8% had an emergency cesarean section, and 34% had an operative vaginal delivery. The significant indejjendent risk factors for emergency
cesarean section were older maternal
age, shorter maternal height, heavier
infant birthweight, and long labor.
The risk factors for operative vaginal
delivery were older maternal age,
shorter maternal height, heavier infant birthweight, epidural anesthesia,
labor/delivery complications, male
infant, private patient status, and being married.
Conclusions. This multivariate
analysis confirms known risk factors
for operative delivery in low-risk
primiparous women and suggests
that it may be possible to predict the
likelihood of operative delivery for an
individual woman by using knowledge of maternal age and height and
assessment of infant birthweight.
(AmJ Public Health. 1994;84:37-42)
Methods
This study was carried out on existing computer files of the Western Australian Midwives' Notification of Case Attended Form 2, which are linked to the
Western Australian Hospital Morbidify
Data System, for the year 1987. The Midwives' Form is a statutory document completed by the midwife in attendance at
each live birth and stillbirth in Western
Australia, provided the infant is at least of
20 weeks gestation or 400 g birthweight.^
There are about 25 000 births annually in
Western Australia.
All primiparous women with low-risk
pregnancies who gave birth in Western
Australia in 1987 were selected. We defined low-risk pregnancies as follows: (1)
singleton infant, (2) no recorded medical
conditions or pregnancy complications,
(3) vertex presentation of the infant, and
(4) sfKjntaneous commencement of labor
at term (at least 37 weeks).
Women whose pregnancies fulfilled
these criteria were divided into three
groups according to whether they had a
spontaneous vaginal, operative vaginal
Read et al.
(vacuum or forceps), or emergency cesarean section delivery. There were no elective cesarean sections because these
women, by definition, all had spontaneous
onset of labor.
Frequencies of selected demographic
and perinatal characteristics for women in
the three groups were coded, as shown in
Table 1, in preparation for multivariate
analyses. The "other" category of maternal race comprised mostly (78%) Asian
women. With regard to patient classification, the universal health care system in
Australia provides public hospital care by
hospital doctors. In addition, people may
obtain insurance that provides for treatment in private or public hospitals by doctors of their own choice. We chose a priori
to investigate the variables in Table 1, together with maternal age and height, either
because they have known associations
with pregnancy outcome or because they
are apparent early in the pregnancy and
can therefore be useful predictor variables
if shown to be significant. Maternal age
and height can always be determined at
the first antenatal visit, and we were particularly interested in these variables as
potential independent risk factors for operative delivery.
Egret software (Statistics and Epidemiology Research Corporation, Seattle,
Wash) was used to perform two separate
multiple logistic regression analyses.^
First, we identified the significant independent risk factors for emergency cesarean section relative to spontaneous vaginal delivery, and, second, we carried out
a similar analysis for operative vaginal relative to spontaneous vaginal delivery.
A two-stage logistic regression procedure weis used tofitthe initial models. In
the first stage, the demographic variables
(maternal race, maternal area of residence, marital status, patient classification, maternal height, and maternal age)
were added, followed by the perinatal
variables (infant gender, infant birthweight, hours of labor, labor/delivery
complications, and anesthesia/analgesia)
in the second stage. At each stage, the
nonsignificant variables were left in the
model. The anesthesia/analgesia and
labor/delivery complications variables
were not used in the emergency cesarean
section analysis because these items were
recorded as positive for almost all women
who had emergency cesarean sections
(the labor/delivery complications were the
indications for cesarean section). Eight
women whose maternal height was not
known and 44 whose patient classification
Results
Of the 3641 primiparas with low-risk
pregnancies who gave birth in Western
Australia in 1987, 2116 (58%) had a spontaneous vaginal delivery, 1242 (34%) had
an operative vaginal delivery (642 forceps,
600 vacuum), and 283 (8%) had an emergency cesarean section.
Table 1 shows the numbers and percentage distribution of women in each delivery category for selected demographic
and perinatal variables. Labor or delivery
complications were recorded for all but
three of the women who had emergency
cesarean sections. The indication for cesarean section for two of these women
was long labor; the third gave birth to an
infant who required intubation. Women
could have had more than one complication (indication) recorded, and those recorded most frequently were ccphalopelvic disproportion (56%), fetal distress
(40%), and failure to progress (27%). In
addition, 16% had other complications recorded, such as antepartum hemorrhage
and prolapsed cord. By contrast, labor
and delivery complications were recorded
for only 48% of the women who had operative vaginal deliveries (3% had cephalopehdc disproportion, 20% had fetal distress, 10% failed to progress, and 21%
experienced other complications). However, for some of the women in this group,
the processes that led to an operative delivery would have been recorded elsewhere (e.g., a long labor would have been
recorded under "hours of labor").
Women who were younger and taller
were less likely to have had operative deliveries than women who were older and
shorter (Table 2). Generally, within each
maternal height category, the percentages
of women with operative deliveries increased with increasing maternal age.
Within each maternal age category, the
percentages of women with emergency
cesarean sections increased with decreasing height; however, this trend was not
seen for operative vaginal deliveries, except in those women 35 years of age or
more (Table 2).
Table 3 shows the results of the multiple logistic regression analysis in which
significant independent risk factors for
emergency cesarean section were compared with those for spontaneous vaginal
delivery. Among the potential demographic risk factors analyzed, the most
important were maternal height and maternal age, the odds ratio increasing with
decreasing maternal height and increasing
maternal age. All of the selected variables,
with the exception of anesthesia/analgesia
and labor/deliveiy complications, were included in this model; however, the area
of residence, marital status, maternal
race, and infant gender variables were
not significant when all of the other variables were entered (data not shown). Although the patient classification variable
was not significant in the model, it has
been included in Table 3 because it represents an area of special interest with
regard to the debate concerning the progressive rise in cesarean births. Private
patient status was significantly associated
with the outcome of emergency cesarean
section until maternal age was added to
the model. There were few private patients in the younger age groups; thus,
any association between being a private
patient and having an emergency cesarean section was due to private patients
being older (data not shown). With regard
to the perinatal variables, heavier infant
birthweight and long labor were significant independent risk factors for emergency cesarean section.
Short maternal height was a significant risk factor for operative vaginal delivery, although there was little difference
in the odds ratios for women less than 160
cm in height and those 160 to 164 cm in
height. Maternal age was also a significant
predictor, the odds ratio for operative vaginal delivery increasing with each older
group (Table 4). In contrast to the risks for
emergency cesarean section, private patient classification and being married remained significant risk factors for operative vaginal delivery, even when the other
variables were added to the model. As
with the emergency cesarean section analysis, infant birthweight was a significant
independent risk factor for operative vaginal delivery. Both labor/deliveiy complications and anesthesia/analgesia were significant independent risk factors for
operative vaginal delivery when all other
variables were included in the model, and
epidural anesthesia was the most significant risk factor of all those included in the
model (Table 4).
Table 5 shows that the estimated
odds ratios increased as maternal age increased and maternal height decreased;
thus, women 35 years of age or more and
less than 160 cm tall were at the highest
risk. In Table 6, the estimated odds ratios
increased with maternal age within each
height category but did not vary greatly
between the height groups.
Estimated odds ratios for each maternal age/matemal height/infant birthweight category (unadjusted for other
factors) were also obtained for both emergency cesarean section and operative vaginal delivery. The complete results from
this analysis are not shown because there
were small numbers in some of the cells.
For example, in Table 5, there were fewer
than five women in three of the categories,
and these women would have been subdivided further into the three birthweight
categories. However, with larger numbers
of deliveries available for analysis, it
would be useful to examine the combined
risk for operative delivery according to
birthweight of the infant as well as age
and height of the mother. As an example,
in one of our categories with a satisfactory number of women for analysis (those
25 to 29 years of age and 160 to 164 cm
tall), the estimated odds ratios for emergency cesarean section relative to spontaneous vaginal delivery were 7.2 if the
infant's birthweight was less than 3000 g,
14.9 if birthweight was 3000 through 3499
g, and 34.0 if birthweight was 3500 g or
more. The estimated odds ratios for operative vaginal relative to spontaneous
vaginal delivery for women in the same
age/height category were 3.3 if the infant's birthweight was less than 3000 g,
5.4 if birthweight was 3000 through 3499
g, and 9.4 if birthweight was 3500 g or
more.
(Vacuum
Spontaneous
Vaginal
(n2116)
Characteristic
(Regresstoi Analysis Code)
No.
Forceps
Emergency
Cesarean
Section
(n 283)
No.
No.
Malemal
Marital status
Unmanied (1)
Man1ed,(2)
. .
V Race '.::.>,
=:,' Caucasian(1)
: ;,: Aborigine-(2)
Other ( 3 ) '
/ : ;-:
',:" '
';
: , Area of residice
K:
Ruta((1).
5 > : Metropditan ( 2 ) ,
. , i .,
':;:
Anesthesia/aialgesia
:
None/btlieH(1) . 'A'--
j//epidurai.(2li
;:'
: , General (3)
1. Labw/delivery compilations
468
1648
22.1
77.9
152
1090
12.2
87.8
44
239
15.6
84.5
1917; :
93 .'
106
90.6
4.4
5.0
1128
28
86
90.8
2.3
6.9
247
10
26
87.3
3.5
9.2
737,
1379
34.8
326
: 916
26.3
73.8
82
201
29.0
71.0
1163
910
43
55.0
43.0
2.0
463
778
1
37.3
62.6
0.1
151
0
46.6
53.4
0
1871
245
88.4
11.6
990
252
79.7
20.3
192
91
67.8
32.2
92.5
7.0
0.5
706
527
9
56.8
42.4
0.7
0
176
107
0
62.2
37.8
72.4
27.6
648
594
52.2
47.8
3
280
1.1
98.9
147
519
576
11.8
41.8
46.4
29
115
139
10.3
40.6
49.1
547
695
44.0
56.0
119
164
42.1
58.0
:.
148 :
11 :
1531
585
Infant
; BIrthweight'g
;/
<3000 (1)
?-
3000-3499(2)
'
3500+(3)'
''
Female; (1)
g-- Male^,,-,
'
, 7
'-:.>:.,
;;;;;:
;-
,,y:'..
463
21.9
980 ; 46.3
673 : . 31.8
1095
1021;
51.8
48.3
Discussion
Most studies of obstetric databases
have been descriptive. More recently,
multivariate techniques have been described in order to control for confounding
factors so that significant independent risk
factors for obstetric outcomes may be ascertained and quantified." However,
there have been few population-based
studies, such as ours (which included all
low-risk primiparas giving birth in Westem Australia in 1987), that use multivariate analyses and include factors such as
Read et al.
Age,y
<20
20-24
25-29
30-34-
35+
Total
160-164
<20
20-54, ,
25-^--*;
30-34
35+
Total
165+
^
-: '
No.
' %"
No.
>
%"
116
190
168
47
5
526
73.9
57.4
47.6
41.6
19.2
17.2
31.4
132 , 37.4
4 7 .= = 41.6
13
50.0
323
101
229
220
77
13
640
69.7
60.6
50.8
53.8
39.4
27.6
31.7
175-C ' 40.4
55 " 38.5
16
48.5
406
27
104
40
120 ;
19.6
ie6-ft-!." 31^8
207
34.3
92
44.0
22 ; 40.7
5ir-jsf.- , . . .
Emergency
Cesarean
Section
Operative
Vagfrilal
%"
14
37
8.9
11.2
15.0
16.8
30.8
157
S31
353
113
26
980
2.8
7.7
8.8
7.7
12.1
145
378
' 433
143
33
1132
2.0
2.8
4.7
5.7
14.8
. =153
503
602
209
54
1521
-19
8
131
4
.29..
': "SB- '
11
4
86
. '^4.
28
12
.8
'
Risk Factor
No.
53
Total
.'T
OR ^ % 01)
Private patient
1.32(0.97,1.7^
Matemal height,
cm*
180-164
<160
2.43(1.70,3.48) <.OO1
5.30 0.72,7.560 <.OO1
Maternal age, y^
20-24
25-29
30-34
35+
.074
1.96(1.12,3.42)
.019
^85 (1.60,5.06) <.OO1
3.31(1.73,6.35) <.OO1
11.87 .24,26.88) <.OO1
infant birthweight, g
3000-3499
3500+
Long labor
( 3 )
.004
1.92(1.24,2.99)
4.16(2.66,6.51) <.OO1
3.74(2.74,5.09) <.OO1
Note. The ncnsignlflcant variables of area of re6idenoe, nrarital stEtus, matemai race, and Infant
sender are not shown, although they were In.
duded Inthe model, OR - odds talio; a oonfldenoeMetval.
"Odds rstiosratsUveto fnatBrna) height of 165 cm or
more.
Xidcls ratios relafive to moemal e of lees than 20
years.
Odds rati08 relative to bitthweight of less than
3000 g.
OR(95%a)
1.74(1.45,210)
1.46(1.12,1.91)
<.OO1
.006
1.38(1.14,1.68)
1.32(1.07,1.64)
<.OO1
,011
1.44(1.05,1.99)
1.59(1.14,221)
2.03(1.39,297)
2.94(1.68,5.16^
1.33(1.13,1.57)
.025
.006
<.0O1
160.-164
165+
Matemal Age, y
No.*
Ockls Ratio
No.*
OtkJs Ratio
No.*
Otkis Ratio
<20
2(^4
25-29
30-34
35+
14
37
53
19
8
4.1
8.1
12.6
14.7
44.1
4
29
38
11
4
2.1
4.0
6.3
7.3
22.1
3
14
28
12
8
1.0
1.9
3.0
3.5
10.7
Maternal age,/>
25-29
30-.34
35-f
Irrlant isirthweight, g
3000-3489
3500+
t^edxxcomplica-
1.52(1.19,1.95)
2.52(1.96,3.24)
Note. One woman whose height was not known was exdudad.
'Number of women with emergency.cesarean seolJona.
<.OO1
<.OO1
<.OO1
TABLE 6Operative Vaginal iSelivery Odds Ratios for Each Matemal Age/Htatemal
Height Categoiy: Primiparous Wrnnen wtth Low-Risk Pregnancies,
Western Austraila, 1987
Matemal Height, cm
2.44(2.06,290) <.OO1
8.37(6.73,10.41) <.OO1
Nota T!ie nan8igiicar variables c area of rs^
denoe; matemai race, and long ietor am not
. 6hawn,diaughttwywerelndudadln<hemocM.
! C^oodcis ratio; Cl<oanfid6nc8inteivad.
Odds ratios relativetD maismal height of 165 cm or
yams.
"HMds ralios relative to blrthwel^ of less than
: 30(g.
<16O
165+
160-164
MatnalAge,y
No.*
Odds Ratio
No*
Odds Ratio
No.*
Odds Ratio
<20
20-24
25-29
30-34
35+
27
104
132
47
1.2
2.2
3.0
3.7
5.3
40'
120
1.2
2.2
2.9
3.7
5.3
30
160
207
1.0
1.8
2,4
3.0
4.4
13
175
55
16
92
22
Note. Two wonien whose heights were not known were exduded.
*Numb6 r of women with operative vaginal delivery.
AcknoMdedgments
The TVW Telethon Foundation (Westem Australia) and the Wellcome Trust (United Kingdom) provided financial support.
Portions of this paper were presented at
the International Conference on Primary Care
Obstetrics and Perinatal Health, 's Hertogenbosch, the Netherlands, March 1991.
We wish to acknowledge the staff at the
Health Department of Westem Australia, particularly Vivien Gee, for the provision of midwives' data. We thank Maxine Croft, John Gibbins, and Carol Garfield, who maintained the
Matemal and Child Health Research Data Base
at the Westem Australian Research Institute
for Child Health, and Dr Nicholas de Klerk for
statistical advice.
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