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Lisa

DeFrancesco
VP, Global
Investor Relations

Actavis Cautionary Statement Regarding Forward-Looking Statements

Forward-Looking Statement
Statements contained in this presentation that refer to Actavis estimated or anticipated future results or other non-historical facts are forward-looking statements that reflect
Actavis current perspective of existing trends and information as of the date of this presentation. Forward looking statements generally will be accompanied by words such
as "anticipate," "believe," "plan," "could," "should," "estimate," "expect," "forecast," "outlook," "guidance," "intend," "may," "might," "will," "possible," "potential," "predict,"
"project," preliminary or other similar words, phrases or expressions. For instance, any statements in this presentation concerning prospects related to Actavis strategic
initiatives, product introductions and anticipated financial performance are forward-looking statements. It is important to note that Actavis goals and expectations are not
predictions of actual performance. Actavis performance, at times, will differ from its estimates, goals and expectations. Actual results may differ materially from Actavis
current estimates and expectations depending upon a number of factors affecting Actavis business. These factors include, among others, the inherent uncertainty
associated with financial projections; variability of revenue mix between Actavis Pharma, Specialty Brands, and Distribution business units; successful integration of
strategic acquisitions and the ability to recognize the anticipated synergies and benefits of such acquisitions; the difficulty of predicting the timing and outcome of pending or
future litigation and government investigations and risks that an adverse outcome in such litigation or investigations could render Actavis liable for substantial damages or
penalties; the impact of competitive products and pricing; risks related to fluctuations in foreign currency exchange rates; periodic dependence on a small number of
products for a material source of net revenue or income; variability of trade buying patterns; changes in generally accepted accounting principles; risks that the carrying
values of assets may be negatively impacted by future events and circumstances; the timing and success of product launches; the difficulty of predicting the timing or
outcome of product development efforts and regulatory agency approvals or actions, if any; risks and uncertainties normally incident to the pharmaceutical industry,
including product liability claims and the availability of product liability insurance on reasonable terms; market acceptance of and continued demand for Actavis products;
difficulties or delays in manufacturing; the availability and pricing of third party sourced products and materials; successful compliance with governmental regulations
applicable to Actavis facilities, products and/or businesses; changes in the laws and regulations, including Medicare, Medicaid, and similar laws in foreign countries
affecting, among other things, pricing and reimbursement of pharmaceutical products and the settlement of patent litigation; risks that resolution of patent infringement
litigation through settlement could result in investigations or actions by private parties or government authorities or agencies; and such other risks and uncertainties detailed
in Actavis periodic public filings with the Securities and Exchange Commission, including but not limited to Actavis plcs Quarterly Report on Form 10-Q for the year ended
September 30, 2013 and from time to time in Actavis other investor communications . Except as expressly required by law, Actavis disclaims any intent or obligation to
update these forward-looking statements.
Statements contained in this presentation that refer to Actavis financial results for 2013, including fourth quarter and/or full year 2013 revenues, earnings, tax rates,
margins, profits, and other financial metrics, are preliminary estimates and reflect Actavis expected financial results as of the date of this presentation, and are subject to
change. Such statements are forward-looking statements that reflect Actavis current perspective of existing and information as of the date of this presentation. Actual
results may differ materially from Actavis current estimates and expectations depending upon a number of factors affecting Actavis business. These factors include, among
others, the inherent uncertainty associated with financial estimates and preliminary results; the possibility that financial estimates and results will change after further review
by Actavis management or accountants, or due to discovery of additional or revised information or subsequent events, and other uncertainties detailed in Actavis periodic
public filings with the Securities and Exchange Commission, including but not limited to Actavis plcs Quarterly Report on Form 10-Q for the year ended September 30, 2013
and from time to time in Actavis other investor communications . Except as expressly required by law, Actavis disclaims any intent or obligation to update these forwardlooking statements.
Trademarks noted in this presentation are the property of their respective registered owners.

Paul Bisaro
Chairman and
CEO

Exceptional 2013
Strong commercial performance in high-value markets
Investment in R&D delivering extraordinary results in
Filings/Approvals
Global Operations maximizing cost efficiencies and driving synergy
capture
M&A driving transformation to Specialty Pharmaceuticals
leadership
The Result - Exceptional Financial Performance
Double-Digit Earnings Growth

Exceptional Cash Flow

Significant 1 Year Progress Against Objective

2013-2018
Strategic Objective
Make Actavis a premier global
specialty pharmaceutical
company continuously
delivering sustainable, longterm growth across all
components of our diversified
strategy.

Created Top 20 global pharmaceutical


company by sales
Leadership in Womens Health
Stronger in Urology
Expanded Specialty portfolio

Gastroenterology and Dermatology

Substantial operational synergies coupled


with tax savings from new corporate
structure

Focus on 2014 - Pillars of Growth

Commercial Strength Maximize value of current business


assets to grow revenue and profit

Organic Growth Invest in focused Gx, Rx, Biosimilar R&D;


deliver the pipeline

Operational Excellence Focus on quality, efficiency, synergy


capture and cost control

Business Development Define opportunities that enhance


growth potential execute strategic transactions

New Leadership Structure

PAUL BISARO
Chairman and CEO

SIGGI OLAFSSON
President, Actavis
Pharma

FRED WILKINSON
President, Global
Research & Development

BOB STEWART
President, Global
Operations

New Leadership Structure and Functions


PAUL BISARO
Chairman and CEO

SIGGI OLAFSSON
President, Actavis
Pharma

FRED WILKINSON
President, Global
Research & Development

Global Commercial Sales


Generics
Brands
Branded-Generics
OTCs
Medis
Global Business Development
& Portfolio Management

Global R&D
Generics
Brands
Inhalation
Biologics/Biosimilars
R&D and Business Dev
Global Regulatory Affairs
Global Pharmacovigilance

BOB STEWART
President, Global
Operations

Global Quality
Global Manufacturing, Supply
Chain, Distribution
Global Human Resources
Global Security, IT
Global Ops Excellence
Global Integration Support
Anda Distribution

Aligning Management to Support Pillars of Growth


Redefining Commercial Structure to Focus on Delivering Integrated
Pharmaceuticals Portfolio Globally
Combining Commercial Generics, Brands, Branded Generics, OTCs, Biologics
sales

Redefining R&D Structure to Capitalize on Capabilities while Maintaining


Differentiated Development Teams
Capitalizing on and Efficiencies in Global R&D, Regulatory Affairs, Clinical
Operations, Pharmacovigilance

Redefining Responsibility of Global Operations Organization


Capitalize on expertise and proven track record in cost containment, synergy
capture, integration management
Enhance utilization of human resources and capabilities and capital investments
to build industry leading specialty pharmaceutical company

2014 Segment & Revenue Reporting Structure

ACTAVIS
PLC

SEGMENTS

North American
Gx

ACTAVIS
PHARMA

North American
Rx*

ANDA
Distribution

International
Rx/Gx/OTC/Third-Party

REPORTING UNITS

* Reporting in each category:


Women's Health, Urology/Gastroenterology, Dermatology/Established Brands

Agenda
Actavis Pharma
Siggi Olafsson, President
Global Research and Development
Fred Wilkinson, President
Global Operations
Bob Stewart, President
Global Finance
Todd Joyce, Chief Financial Officer
2014 Forecast and Beyond
Paul Bisaro, Chairman and CEO

Actavis Pharma
Siggi Olafsson
President

Agenda: Actavis Pharma

Global Organization 2013 Highlights


Global Commercial Highlights

ACTAVIS
PHARMA

Commercial Structure

North American Specialty Brands


North American Generics

North American Gx

International
Medis Third-Party

2014 Objectives and Outlook

North American Rx

International
Rx/Gx/OTC/Third-Party

Actavis Commercial Organization Structure

Siggi Olafsson
Commercial
Operations

Global BD

Canada &
LATAM

International

U.S.

UK &
Ireland

N-Europe

MEGT

Russia, CIS
& Ukraine

Central
Europe

SE-Europe

APACA

Womens
Health
International

Medis ThirdParty

Specialty Brands

Womens Health

Urology/GI

Canada

Strategic Marketing
& Health Economics

Dermatology &
Established Brands

Business Operations

Specialty Commercial Structure Maximizes Growth Potential


A global pharmaceutical
company marketing brands,
branded generics, generics, and
OTC products

Many markets are hybrids of Rx, Gx,


and Branded Generics

Common commercial platform


outside of U.S.

Synergies exist in the support


functions distribution, customer
service, contracting

Rx segment will continue to grow as


we bring differentiated products to
our customers

Hx
International

25%

11%
OTC

Specialty N.A.

37%

16%

30%

36%

Generics N.A.

* Proforma Sales with full year Warner Chilcott, excludes Western European
markets to be divested, Medis excluded from channel split

45%

2013*

Gx

Rx

Actavis and Warner Chilcott Integrations

Complete
US Commercial

International Commercial

R&D

G&A / Shared services

Ongoing

Supply Chain

Exceptional Execution
Integration Essentially Complete

2013 Significant Accomplishments


Strong performance across all business segments
-

Specialty brands showed growth in all key promoted products in U.S. & Canada;
successful new launch in Canada of Fibristal

Strong growth in U.S. generics holding #1 or #2 market positions throughout the


year

UK, Russia and the Nordics had an exceptional year showing growth across all
product categories, brands, branded generics, generics and OTC

Optimized International commercial structure and regional focus for future


growth
Impressive execution in R&D this year, expanding robust pipeline for the
future

Foundation for Global Specialty Pharma

Generics and Specialty Brands

Generics and OTC

Brands

Third-party business (alone)

North American
Specialty
Brands

North American Specialty Brands 2013 Overview


2013 Specialty Brands
Net Revenue ($ millions)
$635+

WC
Actavis

$131

$145

$154

Q1

Q2

Q3

Actavis:
Growth in key promoted products:
Generess Fe, Rapaflo, Crinone
and Androderm
Warner Chilcott:
Delzicol launched in March 2013
Minastrin and Lo Loestrin are the
largest franchises of promoted oral
contraceptives
Five product approvals and three
new product launches in 2013

Q4*

* Q4 Data is based on preliminary results

North American Specialty Brands

Significant Potential New Product Opportunities From Existing Pipeline


2013
Oxytrol OTC
Fibristal (CA)
Minastrin 24 Fe
Doryx 200mg
Delzicol
Rapaflo (Brazil)

2014
LoLoestrin (CA)
Levosert (Int)
Diafert (Int)
Metronidazole
Trelstar (CA)
Crinone NG

NG = Next Generation

2015
Udenafil ED
Mesalamine NG
Levosert (US, CA)
Diafert (US)
ella (CA)
Generess Fe (CA)
Doryx NG

2016+
rFSH
Bx Herceptin
Bx Avastin
Bx Erbitux
Bx Rituxan
Udenafil BPH + ED
Esmya (US)
E4/Progestin OC
Sarecycline
Albaconazole

Specialty Brands Expansion Further Diversifies Actavis


Actavis Specialty Sales
North America
~ $2.5 B

Actavis Specialty Contribution


Global Pharmaceuticals
100%

100%

18%
~40%

ACT Specialty

$1.1 B*
ACT Pharma

2013

2014
Est.

* Includes 4th Quarter Sales of Warner Chilcott

2013

2014
Est.

Specialty Brands Highlights


MAY

AUGUST

Acquired Rights To
Metronidazole 1.3%
Vaginal Gel

Acquired
Albaconazole
Antifungal Agent

JANUARY

JUNE

OCTOBER

Acquired Uteron
Pharmaceuticals

Acquired US Rights
to Levosert

Acquired Warner
Chilcott

2013
FEBRUARY

MARCH

APRIL

JULY

Approval of
Delzicol

Launched
Delzicol

Approval of
Doryx 200mg and
Minastrin 24 Fe

Launch of
Doryx 200mg and
Minastrin 24 Fe

Strong Portfolio of US Marketed Products

WOMENS HEALTH

URO

GI

*
*Co-promoted

DERMATOLOGY

U.S. Sales Force

WOMENS HEALTH

UROLOGY

GASTROENTEROLOGY

DERMATOLOGY

~300

150

95

65

Representatives

Representatives

Representatives

Representatives

Strategic Account Specialists:

~55 Reps

Total U.S. Sales Force: 750

2013 N.A. Specialty Sales by Franchise

2013 N.A. Specialty Proforma*


Womens Health
Urology/GI
Dermatology and
Established Brands

* Based on Proforma Sales for Warner Chilcott

CONTRACEPTIVES: $600+ Million Franchise in the U.S.

Moderate Growth
expected in 2014
Bayer

+5%

Teva J&J

5%

1%
4%

90% share of
voice for OCs in
OB/GYN90%
office

Generess Fe
Lo Loestrin Fe
Minastrin 24 Fe

Actavis

Loestrin 24 Fe
2013

Source: IMS Health

2014

WOMENS HEALTH

URO

GI

DERM

ESTABLISHED

Share of Promoted Oral Contraceptives is growing


and Sales Remain Strong
120
100
Lo Loestrin Fe
Minastrin Fe
Generess Fe
Loestrin Fe
Ortho Tri-cyclen Lo
Beyaz

80

60
40
20
0
2013 Weekly TRx
Source: IMS Health Weekly TRx

WOMENS HEALTH

URO

GI

DERM

ESTABLISHED

Leading portfolio in Womens Health includes leading infertility and


hormone replacement products.

2.5

#1 Prescribed HRT for new patients


by OB/GYNs

Crinone

2.0
1.5

+9%

Endometrin

1.0
0.5

0.0
2013 Weekly TRx
Source: IMS Health Weekly TRx

2013

2014
2013

2014

WOMENS HEALTH

URO

GI

Continue to Grow Rapaflo


TRx in a stable market
70
Rapaflo

60
50

150

40

100

30

Androderm
2.5 & 5.0 mg

Androderm
2.0 & 4.0 mg

20

50

10

0
4Q11

ESTABLISHED

Successful conversion of
Androderm to improved strengths

250
200

DERM

0
2Q12

4Q12

2Q13

4Q13

Source: IMS Health NPA Quarterly and Weekly TRx Data

4Q09

4Q10

4Q11

4Q12

4Q13
31

WOMENS HEALTH

URO

Mesalamine franchise
is stabilizing
35

Some share lost during


Asacol discontinuation

Sales decline
expected in 2014
-18%

20
Total Mesalamine
franchise

Asacol HD

15
10

Delzicol

Asacol
HD

Delzicol

10

ESTABLISHED

Asacol

25

15

DERM

25

30

20

GI

Asacol
2013 Weekly TRx

Source: IMS Health Weekly TRx

2013 Weekly TRx

2013

2014
32

WOMENS HEALTH

URO

GI

DERM

ESTABLISHED

Doryx TRx (Jan 2012 Dec 2013, 000 TRx)

Doryx 150mg
Doryx 200mg
Gx 150mg

70
60
50

Dermatology Highlights
Successful Launch of Doryx
200mg in 2013

40

Slow erosion of Doryx


150mg after Gx entry

30
20
10
0
2Q12
Source: IMS Health Weekly TRx

4Q12

2Q13

4Q13
33

Combined Specialty Brands Franchise

Maximize Profits, Select Promotion on Key Products


Established Products

Actonel
Kadian
InFed
Alora
Brevicon
ella
Estrace tablets
Femring
Norinyl

Tri-Norinyl
Oxytrol
Gelnique
Sodium Ferric Gluconate
Actigall
Condylox
Fioricet
Fiorinal
Norco

Sarafem
Estrostep
Ovcon
Microzide
Femcon Fe
FemHRT
Nor-QD
PapSure
PreQue

Actavis Specialty Brands Success Story: CANADA


Growth strategy emerging with notable filings and launches

2014 Lo Loestrin Approval;


Expect Early 2014 Launch

Successful launch of Fibristal


Generess Fe and ella filed

Launched Urology Portfolio


Built Commercial Team

10 products and 60 sales representatives


3 New Product Launches in 2 Years
2 Re-Launches in 2 Years
Revenue from 0 to ~$90M in 3 Years

Significant Scale Acquired


Asacol & Actonel

Robust Portfolio of
Products in Pipeline
Achieved critical
scale and
profitability

North American
Generics

U.S. Generics 2013**


1Q 2013

3Q 2013

2Q 2013

1,135
930

920

895

733

Actavis

Teva

970
718

696

Mylan* Sandoz

943

Actavis

* Sales for North America, U.S. Not Reported

Teva

707

670

Mylan* Sandoz

Actavis

** Based on Public Company Filings

Teva

718

Mylan* Sandoz

North American Generics 2013 Highlights


Key Product Launches

Gx Lidoderm
Lidocaine Patch
Exclusive

Gx Cymbalta
Duloxetine DR
Capsules
Shared Exclusive

Gx Zovirax
Acyclovir Cream
Limited players

Gx Suboxone
Buprenorphine +
Naloxone Sublingual
Tablets
Limited players

>$500 million revenue from U.S. Generic launches in 2013

North American Generics


Key FTF Launch Opportunities and 30 Month Stay Expirations
(Green Date Certain Launches)

2014
Gx Testim
Gx EpiDuo
Gx Daytrana
Gx Gralise
Gx Xopenex HFA
Gx Exjade
Gx Exelon Patch
Gx Celebrex
Gx Micardis
Gx Lialda
Gx OxyContin
Gx Intuniv

2015
Gx Zipsor
Gx Beyaz
Gx Safryal
Gx Fortesta
Gx AndroGel 1%
Gx Namenda
Gx Ortho Tri-Cyclen Lo

2016+
Gx Suboxone Film
Gx Acanya
Gx NuvaRing
Gx Absorica
Gx Axiron
Gx Nucynta IR/ER
Gx Crestor
Gx Ziana
Gx Azilect
Gx Zyclara

Durable Portfolio
5-Year Sales Benchmark

% of Sales

100
Top 40
Top 30
Top 10
Top 20

80
60
40
20
0

1/2009

1/2010

1/2011

1/2012

Source: IMS Data 2009 2013 3-month periods

1/2013

1/2014

Top U.S. products 5 years


ago still retain the
majority of their value
today

The right generic


products can maintain
significant value or even
grow long-term

Top 7 US Buying Entities are ~85% of Gx Market


CVS/Caremark/
Cardinal

Other
Anda

Trends to Note
Global consolidation
among buyers

Rite Aid

Formation of purchase
alliance groups

Walmart
Walgreen/
ABC

McKesson
Econdisc

Large global generic


players best positioned

Canada Generics
2013 Net Revenues $128M
8 products launched in 2013
20 Rx product submissions in 2013

Building OTC Portfolio


Increased Patent Challenge Activity,
including Injectable
Supply chain management improvement
Focus on portfolio diversification
McKesson Award for service excellence

International

Actavis Pharma International

No 1
Bulgaria,
Iceland, Malta,
Mongolia,
Singapore,
Sweden

Top 3
Denmark,
Greece, Hong
Kong, New
Zealand,
Norway, Serbia
UK

Top 5
Australia,
Austria, Estonia,
Finland, Ireland,
Lithuania

Top 10
Czech,Hungary
Latvia, Romania,
Russia,
Switzerland,
Ukraine

Redefined International Focus Markets


Examples
Strong, profitable
lead markets

Growth
Opportunities

Optimize

Reduced focus/
Out-license
countries

Russia
UK
Nordics

Japan
Brazil/Mexico
South-East Asia
Middle East

Australia
Greece

France
Germany
Italy
Spain

Focusing internal
resources and
investments to optimize
value and growth

Diverse Platform for Future Growth


International
Channel Split by 2013 Sales*
Hospital

Opportunities for growth


across all channels

11%
OTC

37%

16%

36%

Rx

Investing in Sales &


Marketing to grow Rx and
OTC segments
Leveraging pipeline across
multiple regions

Gx
*Excludes Third Party and recently announced Western European divestiture markets

Initiated a Shift in Western European Markets


Signed Term Sheet to Divest Businesses
to Aurobindo

Actavis retains:

Closing expected in March


Select generic commercial operations:
France, Germany, Italy, Spain, Portugal,
Netherlands & Belgium

Estimated 2013 revenues of $466M

Transfer of related commercial


infrastructure, products, pipeline
Conditional on certain antitrust approvals
and completion of employee consultation
processes.

The Third-Party
business
(Medis/Specifar) and
manufacturing plants
The freedom to
operate in the
Specialty Branded and
biosimilars business

Europe
2013 Net Revenues $1.4B
Strong #4 Market Position
458 Product Launches, 313 Submissions
Major product launches on target

Strong Cluster Performance


Outstanding contribution:

2013 Revenue Breakdown**

UK/Ireland taking advantage of shortages.


Strong performance of Rx segment and OTC
Russia strong performance in Rx segment
and OTC
Central Europe strong growth in revenue and
contribution
Nordics capitalizing on strong market position
*Based on preliminary results. Excludes recently announced divestiture of Western European
markets. Includes Warner Chilcott for the fourth quarter of 2013.

** Data based on Actavis Pharma only

MEGT (Middle East, Greece and Turkey)


2013 Net Revenues: $125M*

30 Launches, 17 Submissions

Strengthened Regional office in Dubai

Largest Markets: Turkey, Greece and Saudi Arabia


7% 2013

Strong potential for growth in specialty 9%


franchises

Strong focus on building portfolio

Turnaround in Turkey

7%

Branded Gx markets

11%

Turkey

7%
7%

Turkey
Greece

36%
36%

9%

Greece

Saudi
Arabia
Saudi Arabia

Iraq
Iraq

11%

Iran
Iran

Other

Greece outperforming market

30%

30%
*Based on preliminary results

Revenue Breakdown

Other

APACA (Asia-Pacific, Africa)


2013 Net Revenues: $300M*

71 Launches, 86 Submissions

Establishing regional office in Singapore

2013 Revenue Breakdown


Focus on strengthening portfolio
Strong performance of New Zealand,
Vietnam, Hong Kong and Malaysia

Australian business consolidated as Actavis


Redefining S&M strategy in Indonesia
Divested business in China
*Based on preliminary results

5%
5%
6%
6%
PacificPacific
(AUS & NZ)

6%
6%

Asia Asia
Indonesia
Indonesia

10%
10%

51%
51%

South South
Africa Africa
North North
Africa Africa

22%

22%

Japan

Japan

LatAm
2013 Net Revenues: $25M*
Mostly Brazil
Smaller contributions from Mexico and Colombia
7 Product Launches, 18 Submissions
Approval of Rapaflo in Brazil

Strengthened sales force in Brazil


Established Actavis Mexico
Entrance with oncology in Colombia
Pending Market Authorizations end 2013:
12 in Mexico,
22 in Brazil and
8 in other countries in the region
*Based on preliminary results

OTC
New Products, Line Extensions, New Territories
Russia and Ukraine
Blockbusters
Troxevasin and Spasmalgon line
extensions
Entered allergy segment in Russia

Dental Range
iWhite in Sweden and Norway
new territories in making
Launch of Oralflux in Czech
and Poland
Preparing Flux launch in
Greece, Slovakia and Serbia

Decubal
Launched in Greece in 2013
Preparing launch in ME

Lactocare
Launched in Finland and Norway
Preparing launch in Greece and in
Turkey under ProBac brand name

Future Product Opportunities


Market
Opportunity

Capabilities
Center of Excellence London

Inhalation

Injectables

Ophthalmics
& Otics

$37+ Billion
global market
Limited Generics

$20+ Billion
global Generic market
Many new Rx targets

$13+ Billion
global market
Limited Generics

Dedicated leadership,
expanding team
Partnerships for devices and
manufacturing
Strong capabilities in R&D,
(cytotoxic, pre-filled syringes)

Two injectable manufacturing


plants FDA inspected
Partnerships established for
complex technologies
Strategic global partner
and co-development
Selective licensing based
on timelines and product

Development
Targeting products covering
>50% of global market;
- MDIs and DPI
- Nasal Sprays
Robust pipeline of more than 50
products

- 505(b)(2) NDAs
- Complex injectables
- Strong oncology focus
Targeting all dosage forms;
- Suspensions

- Solutions
- Gels and ointments

International Specialty Brands

Mesalamine
Franchise

Focus on UK
Product
continues to
grow
Opportunity to
expand into
selective
markets

Womens Health

Building portfolio
throughout the region
OCs
Progesterone
Cacit
Tests

New Launches
Levosert
Diafert

Medis Third-Party
2013 Highlights
Integration of Medis, Specifar, Breath and
Spirit complete one unified business
215 new agreements signed in 2013 (highest
number ever achieved)

Record 215 new agreements


signed on 103 products with 91
companies
215
200
189

50 contract extensions (prolongations)


Diverse Customer base
-

211 active customers covering the full range from


top Gx players to small local start-ups

Global coverage of 130 countries

129

Progressing with expansion into new emerging


markets

2010

2011

2012

2013

Looking Ahead: 2014 Specialty Brands

Womens Health

Appropriately
position portfolio of
OCs to drive growth
Focus on Lo
Loestrin &
Minastrin
Accelerate growth of
Estrace Cream

Uro /GI

Accelerate growth of
Rapaflo
Grow GI franchise
and enhance market
access position
Maximize opportunity
for Delzicol in
Ulcerative Colitis
Expand portfolio

Derm / Established
Brands

Capitalize on Womens Health product launches in


Canada, including Fibristal and LoLo

Accelerate growth of
Doryx 200mg
Opportunistic
marketing of select
established brands

Looking Ahead: North American Generics


No change in strategy - stay the course and execute
- Maintain U.S. market as a key focus for the
organization
- Continue focus on developing complex, high barrier
products and patent challenges
- Grow Canada portfolio with differentiated product
offering

Looking Ahead: International


Specialty
Launch Diafert and Levosert
Emerging leadership in Womens Health

Europe and Eastern Europe

Expand sales force in key markets

Expand portfolio

Improved on already strong market position

APACA & MEGT

Expand portfolio

Business development opportunities to increase scale

Expand geographically within region

2014 Outlook
2014 Forecast
Net Revenues
North American Brands
Womens Health

~$8.7B
$2.4B - $2.5B
$1.0B - $1.1B

Urology / Gastroenterology

$850M - $900M

Dermatology / Established Brand

$500M - $550M

North American Generics

$3.9B - $4.0B

International Revenue

$2.2B - $2.3B

* Excludes recently announced divestiture of European Markets. Refer to tables at end of presentation for a reconciliation
of non-GAAP items.

Global R&D
Fred Wilkinson
President

Agenda: R&D

Organization and Capabilities


Generic R&D Update
Global Specialty R&D Update

Biosimilars R&D Update


2014 Objectives

Actavis R&D Organization Structure


Actavis R&D
Fred Wilkinson

Inhalation

Gx Development

Generic

Gx Clinical

Pharmacovigilence

Gx Regulatory

Gx Proj Mgt
Global PM

Solid Oral
Dosage

Internal Gx
(India)

International Gx

Semi-Solid &
Liquid

Internal Gx
(Florida)

US Gx Regulatory

Hospital/
Injectables

External Gx

API

Specialty
Brands

Biosimilars

Wom Health &


Medical Affairs

Develop &
Manufacturing

Urology/GI
Dermatology

Scientific
Officer

Brand
Regulatory

Project
Management

Biosimilar
Strategic Planning

Powerful Global R&D Combination

Combining generic, specialty, inhalation and biosimilar R&D


Development will remain separate for each category
Generic R&D will focus on Generics
Brand R&D will focus on Brands
Biologics R&D will focus on Biosimilars

Maintain commercial input from business areas


Coordinate and streamline R&D support functions to increase
efficiency
Regulatory
Pharmacovigilance

Elimination of duplicate processes allows savings to be reinvested


Collaboration between teams adds powerful advantage and will
enhance success

Global R&D Network


IR Oral Solids

India
Iceland
Larne, Northern Ireland
Belgium

MR Oral Solids
Florida, USA
New Jersey, USA
Bulgaria

Hafnarfjordur Iceland

Patch/Topicals
Utah, USA
Maryland, USA
Bulgaria

Dundalk Ireland

Injectables
Italy
Romania

Larne Northern Ireland


Liege Belgium

Elizabeth, NJ USA
North Brunswick, NJ USA

Bucharest Romania
Troyan Bulgaria

Owings Mills, MD USA


London UK
Liverpool UK

Salt Lake City, UT USA

Bangalore India

Others
Lotus BE and CE
studies, India
CRO in Miramar, FL
Inhalation/new
technologies, UK,
North Brunswick, NJ
Indonesia (Local R&D)
API development,
India
IUD, Clinical,
Regulatory, Liege,
Belgium

Chennai India

Jakarta Indonesia

Weston, FL USA

Miramar, FL USA
Nerviano Italy
Navi, Mumbai India

Ambernath India

Clinical Ops
Utah, USA
NJ, USA
Larne, Northern
Ireland
Belgium

Commitment to Organic Growth through R&D*


Internal development by year, in millions

29%

14%

57%

* 2013 Includes one quarter Warner Chilcott; Based on Preliminary Results

Generic R&D

Realizing Value of Watson/Actavis Combination*

25%+ capacity for


additional projects
Consolidation
of overlap

~50%
Overlap
Non-Overlap

Actavis
2012

Watson
2012

*Illustrative Purposes Only

2013+

Synergies capture
results in increased
number of projects

2013 Generic R&D Performance


New Dossiers/ANDAs by Year

2013 Highlights

~240
Japan

Australia
Russia
153

Other
EU
CA/
LatAm

111

.U.S.

2012 *

2013

* Proforma for Watson and Actavis

2014
Opportunties

Delivered filings across all dosage forms


and regions
Expanded in-house capabilities
- Clinical site in the U.S.
- Inhalation team in London
Reinvesting savings from R&D
efficiencies into new complex products
Robust filing plan for 2014, we have
more opportunities to work on than ever

Actavis the Leader in U.S. First-to-files


Confirmed First-to-File # Products in 2013 by Company
18
Exclusive FTF

Shared FTF

12

10
3
6
2
6

5
1

5
1

7
4

4
1

4
1

Actavis Sandoz Mylan Amneal Apotex Hetero Glenmark Zydus

3
1
2
Teva

Roxane Alkem
Labs

Source: FDA website, Public lawsuits, Internal Analysis


Note: Total is greater than 44 due to shared FTFs, FTF company not identified for 6 products

Lupin

Dr.
Others
Reddys (14)

Achieved Significant Share of FTFs in 2013


First-to-File # Products in 20131

Product Sales of FTFs in 20132 ($ in billions)

Exclusive
Shared

$2.1

26
44

Exclusive
Shared

64%
41%

$5.8
$2.7

12

$1.0

6
Total
1
2

Others

Actavis

First-to-Files posted on the FDA website in 2013


IMS Health Sales MAT Nov. 2013

Total

Others

Actavis

PIV Filings Strengthen U.S. Pipeline


Product

Dosage Form

Status

30-Month Stay

Gx Testim

Topical Gel

Limited Filers

2014

Gx Epiduo

Topical Gel

Actavis FTF

2014

Gx Daytrana

Transdermal

Actavis FTF

2014

Modified Release Tablets

Actavis FTF

2014

Metered Dose Inhaler

Actavis FTF

2014

Capsules

Actavis FTF

2014

Gx Exelon

Transdermal

Actavis FTF

2014

Gx Exjade

Immediate Release Tablets

Actavis FTF

2014

Gx Zipsor

Soft Gel Capsules

Actavis FTF

2015

Gx Beyaz

Oral Contraceptive

Actavis FTF

2015

GX Safyral

Oral Contraceptive

Actavis FTF

2015

Gx Fortesta

Topical Gel

Actavis FTF

2015

Sublingual Thin Film

Actavis FTF

2016

Topical Gel

Actavis FTF

2016

Gx Nuvaring

Vaginal Ring

Actavis FTF

2016

Gx Absorica

Capsules

Actavis FTF

2016

Topical Solution

Actavis FTF

2016

Gx Nucynta IR

Immediate Release Tablets

Actavis shared FTF

2016

Gx Nucynta ER

Modified Release Tablets

Actavis shared FTF

2016

Gx Gralise
Gx Xopenex HFA
Gx Revlimid

Gx Suboxone Film
Gx Acanya

Gx Axiron

Yellow = 2013 additions to disclosed pipeline, does not include all filings

53 new U.S.
filings submitted
in 2013
Approx. 70%
included PIV
patent
challenges
20+ additional
potential FTFs
waiting for
acceptance by
FDA

Actavis U.S. Pharma Pipeline Select Categories


Development

Filed

Approved /
Launched

Inhalation

6 active projects, including;


- Meter Dose Inhalers
- Dry Powder Inhalers
- Additional International
projects underway

Xopenex HFA MDI


Nasal Spray

Various nebules

Injectables

More than 30 active projects


including;
- 505(b)(2) NDAs
- Complex injectables
- Strong oncology focus

15 products

16 products (most via


market partner)

Ophthalmics
& Otics

8 active projects, including;


- Suspensions
- Solutions
- Gels and ointments

17 products

Launching 2014+

Significant Expansion of Internal Clinical Study Capabilities


Internal vs. External Studies
~15%
Acquired 160 bed CRO in
Florida in mid-2013

65%

600 beds in 5 locations in


India and 1 location in
Florida
Current Capacity: ~400
studies per year

Internal External

2012

Total

Internal External

Total

2014 Est

Specialty R&D

Specialty Brands R&D 2013 Achievements

APPROVALS

REGULATORY FILINGS

Oxytrol for Women in US


Fibristal (single cycle) in Canada
Crinone New Applicator in US
Rapaflo in Brazil
Trelstar 6 month in Canada
Levosert (Menorrhagia) in UK & 12
Central Eastern European countries
LoLoestrin in Canada

Progestin only patch


Fibristal (multi-cycle) in Canada
ella in Canada
Levosert (Contraception) in UK & 12
Central Eastern European countries
Levosert (Contraception & Menorrhagia)
in UK & +15 EU countries
Generess Fe in Canada

Rationalized Actavis Specialty Pipeline


Preclinical

Phase 1
Colvir HPV

Esmya Vaginal Ring


Vaginate BV

Phase 2
Albaconazole
VVC

Rapaflo NextGen
WC3037
E2 Vaginal Capsules
WC3058
Etonogestrel Ring
WC3081
1mg NA/20 ug EE
Softgels

Phase 3
Esmya-Fibroids
(US)

Metronidazole 1.3%
Vaginal Gel

Diafert

Levosert
Contraception

E4/Progestin OC
WC3079
Delzicol NextGen
WC3046
Delzicol 800mg

WC3011
E2 Vaginal Cream
WC3055
Udenafil BPH
WC3035
Sarecycline

WC3065
1mg NA/10 ug EE
Softgels

WC2055
Doxycycline NextGen

Amg/Act Rituxan

Oxybutynin
Hyperhidrosis

Amg/Act Erbitux

Albaconazole
Onychomycosis

MAA

WC3043
Udenafil ED
Amg/Act
Herceptin
Amg/Act
Avastin

Approved
Fibristal
Canada

Progesterone
Vaginal Gel
Oxytrol OTC (Merck)

Progestin Only Patch

Levosert HUB
UK/EE
WC3040
1mg NA/20 ug EE
Chewable Tablet
WC3064
1mg NA/10 + 10 ug EE
Chewable Tablet
Rapaflo Brazil

rFSH

Rapaflo Canada
Delzicol 400mg

Womens Health

Urology

GI

Contraceptives

Biologic

Dermatology

Doryx 200mg

Womens Health Franchise: Select Portfolio + Pipeline


Levosert (levonorgestrel-releasing IUD)
Indication

Levosert
Contraception

Diafert

Regulatory &
Estimated
Launch

Esmya/Fibristal
E4/ Progestin
OC
WOMENS
HEALTH

Menorrhagia & Contraception

Competition

Market Value

U.S.: NDA expected to be filed


2014
ROW: Approved for menorrhagia
in UK and 12 Countries in CEE &
Launching in 2014;
Contraception submitted in EU
CAN: NDS expected to be filed
2014
U.S.: Mirena/Skyla,
Paragard, Nexplanon
ROW: Mirena/Skyla & non-drug
loaded IUDs
U.S. Market: $890 million (IMS Health)
ROW Market: $406 million + (IMS
Health-MIDAS)

Womens Health Franchise: Select Portfolio + Pipeline

Diafert (non invasive adjunctive IVF selection assay)

Levosert
Contraception

Indication

Diafert
Esmya/Fibristal
E4/ Progestin
OC
WOMENS
HEALTH

Improve embryo selection in IVF


U.S.: 510K expected to be filed
2014
ROW: CE Mark in 2014
CAN: Class II Medical Device
submission 2014

Regulatory &
Estimated
Launch

Competition

No direct competitor

Market Value

U.S.: 154,412 IVF Cycles (SART 2011)


ROW: 877,330 IVF Cycles (ESHRE
2010)

Womens Health Franchise: Select Portfolio + Pipeline


Esmya (Ulipristal Acetate tablets)
Indication

Levosert
Contraception

Diafert

Regulatory &
Estimated

Launch

Esmya/Fibristal
Esmya/Fibristal
E4/ Progestin
OC
WOMENS
HEALTH

Treatment of signs and symptoms of


uterine fibroids
U.S.: Phase 3 uterine-sparing
clinical initiated; NDA expected to
be filed 2016
ROW: Approved & Launched by
GR
CAN: Approved in women eligible
for surgery & Launched in 2013

Competition

Leuprolide for preoperative


hematologic improvements of anemia
caused by uterine fibroids

Market Value

First in class indication potential


millions of women treated annually for
fibroids; >$500* million in U.S. & CAN

*Based on 300,000 hysterectomies annually in


U.S. and CAN

Womens Health Franchise: Select Portfolio + Pipeline

E4 (Estetrol combination Oral Contraception)

Levosert
Contraception

Indication

Diafert

Regulatory &

Estimated

Launch

Esmya/Fibristal

Competition

E4/ Progestin
OC
WOMENS
HEALTH

Oral Contraception

Market
Potential

U.S.: Initiating Phase 3 in 2014


ROW: Initiating Phase 3 in 2014

U.S.: Combination OCs


ROW: Combination OCs

U.S.: $3.6 billion (IMS Health)


ROW: $4.5 billion (IMS Health)

URO / GI Franchise: Select Portfolio + Pipeline


WC3043 (Udenafil tablets)

WC3043
Udenafil ED

Indication

WC3055
Udenafil BPH + ED
WC3046
Delzicol 800mg

Erectile Dysfunction

Regulatory &
Estimated

Launch

Competition

U.S.: NDA expected to be filed


2014 & Launch in 2015
CAN: NDS expected to be filed
2014 & Launch in 2015

U.S.: Viagra, Cialis, Levitra,


Stendra

Market Value U.S.: $2.5 billion

WC3079
Mesalamine NextGen

URO / GI

URO / GI Franchise: Select Portfolio + Pipeline


WC3055 (Udenafil tablets)

WC3043
Udenafil ED

Indication

WC3055
Udenafil BPH + ED
WC3046
Delzicol 800mg

BPH + Erectile Dysfunction

Regulatory &
Estimated

Launch

Competition

U.S.: Initiate Phase 3 in 2014;


NDA expected to be filed 2016
CAN: NDS expected to be filed
2016

U.S.: Cialis

Market Value U.S.: $1.2 billion

WC3079
URO / GI

Mesalamine NextGen

URO / GI Franchise: Select Portfolio + Pipeline


WC3046 (Delzicol 800mg)

WC3043
Udenafil ED

Indication

WC3055
Udenafil BPH + ED
WC3046
Delzicol 800mg
WC3079
URO / GI

Mesalamine NextGen

Ulcerative colitis

Regulatory &
U.S.: sNDA expected to be filed
Estimated
2015 & Launch in 2015
Launch
Competition

Lialda, Pentasa, Rowasa,


Apriso

Market
Potential

$1.9 billion (IMS Health)

URO / GI Franchise: Select Portfolio + Pipeline


WC3079 (Mesalamine NG)

WC3043
Udenafil ED

Indication

WC3055
Udenafil BPH + ED
WC3046
Delzicol 800mg
WC3079
URO / GI

Mesalamine NextGen

Ulcerative colitis & maintenance of


remission

Regulatory &
U.S.: NDA expected to be filed 2014
Estimated
& Launch in 2015
Launch
Competition

Lialda, Pentasa, Rowasa,


Apriso

Market
Potential

$1.9 billion (IMS Health)

Dermatology Franchise: Select Portfolio + Pipeline


WC2055 (Doxycycline NG)
Indication

WC2055

Regulatory &
Estimated
U.S.: NDA expected to be filed 2014
Launch
Competition

Oral doxycycline & minocycline


(Solodyn, Monodox, Oracea,
Minocin)

Market
Potential

$1.2 billion in brand value

Doxycycline NextGen

WC3035
Sarecycline
DERM

Doxycycline class labeling, including


acne

(IMS Health)

Dermatology Franchise: Select Portfolio + Pipeline


WC3035 (Sarecycline)
Indication

WC2055

Regulatory &
Estimated
U.S.: Entering Phase 3 in 2014
Launch
Competition

Oral doxycycline & minocycline


(Solodyn, Monodox, Oracea,
Minocin)

Market
Potential

$1.2 billion in brand value (IMS Health)

Doxycycline NextGen

WC3035
Sarecycline
DERM

Moderate to severe acne

Biosimilar R&D

Biosimilar Franchise: Select Portfolio + Pipeline


rFSH (follitropin alpha)

rFSH

Indication

Amg/Act
Rituxan
Amg/Act
Erbitux
Amg/Act
Herceptin
BIOLOGICS

Amg/Act
Avastin

Development of multiple follicles in


ART program (IVF)

Regulatory &
ROW & U.S.: Initiated Phase 3 in 4Q
Estimated
2013
Launch
Competition

Gonal-F, Folistim, Menopur,


Bravelle

Potential
Value

U.S.: $450 million (IMS Health)


ROW: $1,035 million (IMS Health)

Oncology Biosimilar Programs Progressing to Plan

ABP 215: Bevacizumab (Avastin)


Developed entirely at Amgen
Principal similarity assessment complete
Phase 1 study successfully completed
Pivotal P3 trial has started

ABP 798: Rituximab (Rituxan)


Being developed at Amgen
Final clone selected
Process development in progress

ABP 980: Trastuzumab (Herceptin)


Acquired from Synthon
Tech transfer to Amgen complete
EU P1 successfully completed
Pivotal P3 trial has started

ABP 494: Cetuximab (Erbitux)


Complete Cell Line Development, Actavis

Bob Stewart
President
Global Operations

Global Operations Strategy Simply Stated


1. Supply high-quality products
2. Exceed customer expectations
3. Operate network safely and environmentally
responsible
4. Align operational structure to support end-toend supply chain
5. Continue to maximize Anda capabilities
6. Execute every day

Actavis Global Operations Structure

GLOBAL OPERATIONS
BOB STEWART

Manufacturing
(Americas)

Manufacturing
(ROW)

Global
Engineering

Manufacturing
(Inject)

Information
Technology

Supply Chain

Human
Resources

Operational
Excellence

Quality

Pharmaceutical
Technology

Anda
Distribution

Structure allows for end-to-end supply chain integration

2013 Highlights
Continued transformation to Supply Chain driven
organization
S&OP deployment including 24-month demand forecast
Rationalizing manufacturing network
Lidocaine launch
Integration of Actavis and Warner Chilcott complete
Ongoing rationalization of supply chain

2013 GMP Regulatory Inspections - Summary


47 Regulatory Inspections
FDA
FDA, 11

MHRA/EMA/EDQM
ANVISA
HEALTH CANADA

Other, 23

TGA (Australia)
MHRA / EMA /
EDQM, 6
ANVISA, 3
TGA (Australia), 1

HEALTH CANADA,
1

Other

(AIFA, BDA (Bulgaria), BFSA, DHMA


(+MHRA), Egyptian MOH, SFDA, HSA
(Singapore), MMA, MOH Serbia, NDAMD
(Romania), NOM (Greece), Health Care
Inspectorate and PMDA (Japan)

Global Operations: Manufacturing Capabilities


Manufacturing network ~30 Global Plants
Four New Plants from Warner Chilcott
Manufacturing capacity ~44 Billion Solid Oral Dosage Units
Extensive capabilities in modified release, solid dosage, semi-solids,
transdermals, gels, liquids and injectables
Responsible for producing more than 1,100 generic products and more
than 30 branded products
Capability to produce broad line of products with variety of dosage
technologies

Leveraging Acquired Warner Chilcott Assets


Fajardo, Puerto Rico
Solid Oral Dosage, Tax
Advantages

Manati, Puerto Rico: Solid Oral


Dosage, Tax Advantages

Larne, N Ireland
Devices
Capability

Weiterstadt, Germany
Modified Release
Dundalk, Ireland Stability &
Biologics

Global Supply Chain Optimization

Planned Closures, Sale or


Restructuring
Alathur India
Changzhou City China
Corona, CA USA
Foshan China
Groveport, OH USA
Lincolnton, NC USA
Mississauga, Ontario Canada
Mt. Prospect, IL USA
Podolsk Russia

Zoetermeer The Netherlands

Site Categorization Investment Profile


Rationale
Strategic

Hold

Divest

Investment Profile

Specialized Technology
Low Cost
Portfolio Growth
IP Landscape

High Capital Investment


New Product Registrations
IT Integration

Regional Importance
Cost Profile

Maintenance Capital
New Products
(where makes sense)

No Longer Needed
Redundant Capability

Challenge Headcount
Limited IT Integration

Capital limited to Emergency


No IT Integration
Manage Headcount Decline

Long-Term Manufacturing Strategy Aligned to R&D


Changing demand: Shift from tablets/capsules and
ointments/creams to potent, injectables and special technologies

Changing Finished Dosage Manufacturing Capabilities


Current
Capacity

Type of Mfg.

Growth

Tablets/Capsules

Ointments/Creams
Potent
Injectable
Special Technologies
(ODT, patches)

Investment
Strategy

Rationalize Footprint
Maintain
Invest
Within our
Invest
normal capital
profile
Invest

Relentless Drive for Efficiency


Typical efficiency improvement focus
Manufacturing

Reducing conversion cost (i.e. local lean and OE


initiatives)
Securing manageable plant loads and service levels

Procurement

Improving conditions on API, packaging materials,


excipients

Supply Chain

Quality

Supporting first pass right efforts


Improving quality cost per unit

Engineering

Efficient capacity expansion/allocation programs

Pharm Tech

Improving product transfer/ramp-up cost and times


Improving yields and reducing rejection rates
Optimizing batch sizes

Improving customer service levels


Balancing plant loads
Optimizing inventory levels/turns
Optimizing in-house vs. buy decisions

Product cost
Quality
Service levels
Margin
Improvement

Actavis Integration Engine

Actavis
Integration
Engine

Integration friendly
overall organization
structure

Divisions (Pharma and Specialty Brand) focus on Commercial and R&D


integrations
Operations drives integration of backbone/infrastructure functions
(Manufacturing, SC, Quality, IT, HR)

Dedicated
integration
architecture

Dedicated Integration Office combined with HR oversees and coordinates


all integration activities
Functional line teams responsible for planning/executing functional
integration

Clear targets and


rigorous control

Value creation goals defined before acquisition with clear allocation to


individual teams
Constant monitoring of progress (financial, HR, and content milestones)
with direct reporting into Integration SteerCo

Efficient working
formats and
standards

Standardized working formats across teams


Detailed checklists/playbooks by integration team
Regular cross functional reviews and interdependency checks

2014 Global Operations Priorities


Continue to optimize Supply Network
Drive COGs lower (procurement, conversion, and
distribution)
Shift capital allocation toward new technologies
Capitalize on 2013 investments (IT, Supply Chain, Quality)
Enhance capabilities of global team through best practices in
Human Resources
Drive for excellence in cost containment, efficient utilization
of resources

Anda Overview
Anda, Inc. is the largest distributor within the US competing with the big-3 wholesalers,
with sales exceeding forecast for 2013

Anda purchases and distributes products from 350+


manufacturers, including Actavis, to 60,000 accounts+.

Anda shipped to more than 85% of the pharmacies in the


U.S. in 2013

Andas Divisions
Andas two divisions touch all
trade classes:

Retail
Mail Service
Long Term Care
Specialty Pharmacy
Government
Out-Patient Hospital

Physician
Clinic
In-Patient Hospital

Anda: 2014 Highlights & Growth Drivers


Increased Chain Opportunities Virtual Warehouse
Retail Independents remain a strong segment
Grow AndaMeds
- Physician business growing sales each month after division rebranding
Growth Drivers
Continue to enhance value for large chains
Expand portfolio of products for brands and specialty Be the Primary
Secondary
Anda: 2014 Forecast
Anda Distribution revenue ~$1.5 billion
Adjusted gross margin 11% 13%
Adjusted SG&A 8.5% - 9.5%

Actavis
Financial
Update
Todd Joyce, CFO

Agenda
Achievements and operating trends
Debt trends and capitalization
Revenue diversification and cost trends
Financial reporting changes
Consolidated and segment forecasts

Strong Non-GAAP EPS and Adjusted EBITDA Trends


~33% CAGR

57%+ YOY

*
~34% CAGR

60%+ YOY

*
* 2013 results are preliminary and unaudited and represent the high end of the 2013 forecast range for expected Non-GAAP EPS of $9.26 - $9.39 and Adjusted EBITDA of $2.22 - $2.24 billion provided on October 29, 2013. Reconciliations between
GAAP and Non-GAAP results/expectations can be found in the Actavis October 29, 2013 press release. On January 14, 2014, Actavis disclosed that 2013 results are anticipated to be modestly above this October 29, 2013 Non-GAAP forecast.

2013 Achievements

Strong earnings growth and cash flow generation

Strategically expanded our branded franchise

Seamlessly integrated acquired businesses

Synergies realized as expected

Re-domiciled to Ireland and reduced corporate tax rate

Reduced debt leverage ahead of schedule

Commitment to Organic Growth through R&D*


Internal development by year, in millions

29%

14%

57%

* 2013 Includes one quarter Warner Chilcott; Based on Preliminary Results

Historic Commitment to Rapid Deleveraging

* Preliminary results
** Assumes no additional M&A

Pro-Forma
Leverage

Gross debt

Robust cash flow generation


post-M&A transactions

Delevering Ahead of Schedule


12/31/2013
Capitalization*

Percent
of Total

Leverage
Ratio**

265

1.4%

0.08x

ACT Term Loan

1,310

7.0%

0.40x

WC New Term Loan

1,833

9.8%

0.56x

ACT Notes

4,300

23.0%

1.32x

WC Note

1,250

6.7%

0.38x

94

0.5%

0.03x

9,052

48.5%

2.79x

9,612

51.5%

18,664

100.0%

Cash and Marketable Securities

ACT Revolver

338

Senior Notes

Other
Total Debt

Equity
Total Book Capitalization

* Preliminary. Subject to finalization of 2013 results.


** Leverage ratio based upon last twelve month preliminary pro-forma adjusted EBITDA including Warner Chilcott

Staggered Debt Maturities Provide Flexibility


Projected cash flows and pre-payable debt allows for rapid deleveraging**
2014 Free Cash Flow Estimated between $1.75 - $2.0 Billion

* Company expects to call Warner Chilcott $1.25B 7.75% Senior Notes due 2017 this year
** Excludes impact of M&A

Robust Revenue Growth and Diversification


Significant expansion of brand and international revenues

* Projected. Excludes revenue from recently announced Western European divesture of select commercial markets.

Favorable Non-GAAP Tax Rate Trend

Refer to reconciliation table at end of presentation for a reconciliation of non-GAAP items.

Significant post 14 Cost Reduction Opportunities


OPERATING MARGINS
Further plant and supply chain optimization
Leveraging global commercial capabilities
Procurement savings including API and indirect costs
Further globalization of corporate functions
TAX RATE

M&A structuring through internal leverage


Migration of existing high taxed IP over time
Offshore IP development and new product launches
Selective offshoring of certain activities

2014 Segment & Revenue Reporting Structure


ACTAVIS
PLC

SEGMENTS

North American
Gx

ACTAVIS
PHARMA

North American
Rx*

ANDA
DISTRIBUTION

International
Rx/Gx/OTC/Third-Party

REPORTING UNITS

* Revenue reporting for the following:


Women's Health, Urology/Gastroenterology, and Dermatology/Established Brands

2014 Forecast Key Assumptions


Mid single-digit erosion on U.S. base business

High single-digit price erosion internationally


Additional competition on Gx Lidoderm in Q1 14
Launch of Gx Oxycontin and Gx Intuniv in 2H 14

One additional competitor for Gx Concerta


Mid-year generic competition on Actonel
No further generic competition on other Specialty Brands products

Excludes M&A and business development


Excludes divested operations

2014 Forecast Update

Net Revenues

GAAP R&D
GAAP SG&A
Non-GAAP Tax Rate

Current Forecast

Previous Forecast

~$10+B

~$10B

$800M - $850M
$2,000M - $2,100M
16.5% 17.5%

Adjusted EBITDA*

$3,150 - $3,250M

Non-GAAP EPS*

$12.60 - $13.10

* Refer to tables at end of presentation for a reconciliation of non-GAAP items.

16% 18%

$12.25 - $13.00

2014 Segment Forecast


Segment Revenues, Adjusted Margins, and SG&A% of Revenues

Net Revenues
Adjusted Gross Margin %*
Adjusted SG&A %*

Pharmaceuticals

Anda Distribution

~$8.7B

~$1.5B

63% - 66%

11% - 13%

21.0% - 22.5%

8.5% - 9.5%

* Refer to tables at end of presentation for a reconciliation of non-GAAP items.

2014 Pharmaceuticals Segment Revenue Forecast


Reporting Unit Breakdown

2014 Forecast
Net Revenues
North American Brands
Womens Health

~$8.7B
$2.4B - $2.5B
$1.0B - $1.1B

Urology / Gastroenterology

$850M - $900M

Dermatology / Established Brand

$500M - $550M

North American Generics

$3.9B - $4.0B

International Revenue*

$2.2B - $2.3B

* Excludes recently announced divestiture of European Markets. Refer to tables at end of presentation for a reconciliation of non-GAAP items.

Other Assumptions
INTEREST AND FOREIGN EXCHANGE
Assumes debt paydowns of approximately $2.0 billion

Includes early redemption of $1.25 billion of legacy Warner Chilcott bonds

Key currency exchange rate assumptions:


Currency

FX Rate
in USD

AUD

0.89

CAD

0.95

CHF

1.08

EUR

1.30

GBP

1.54

RUB

0.03

2014 Cash Flow Estimates


2014 Forecast
Operating Cash Flow

$2.0 $2.2 billion

Capital Expenditures

$200 - $250 million

Free Cash Flow*

$1.75 - $2.0 billion

* Cash flow generation sufficient to reduce leverage to 2.2x by year-end

Paul Bisaro
Chairman and
CEO

Driving Long Term Shareholder Value

Global Specialty Industry Realities


Pharmaceutical Industry
Larger / Broader Product Offerings
Converging on Specialty Business Model

Consolidation and M&A


Bolt-ons for scale, commercial footprint, product lines
Synergies a significant driver

Pricing Pressures and Growth in Pharmerging Markets vs Mature


Markets
Consolidation of Customer Base
Duplicating R&D Efforts / Expense in Race for Gold

Two-Prong Commitment to Growth

Double-digit Y-o-Y Organic Earnings Growth


$9.39+

$10.00

38% CAGR

$7.50

$4.77

$5.00
$2.50

$1.37

$2.03

$3.04

$3.42

2009

2010

$6.00

$0.00

2007

2008

2011

2012

Non-GAAP EPS

Strategic M&A / BD to Power Additional Earnings Growth

* 2013 results are preliminary and unaudited and represent the high end of the 2013 forecast range for expected Non-GAAP EPS of $9.26 - $9.39 and Adjusted EBITDA of $2.22 - $2.24 billion provided on October 29, 2013. Reconciliations between
GAAP and Non-GAAP results/expectations can be found in the Actavis October 29, 2013 press release. On January 14, 2014, Actavis disclosed that 2013 results are anticipated to be modestly above this October 29, 2013 Non-GAAP forecast.

2013

Focus on 2014 - Pillars of Growth

Commercial Strength Maximize value of current business assets to


grow revenue and profit

Organic Growth Invest in focused Gx, Rx, Biosimilar R&D; deliver the
pipeline

Operational Excellence Focus on quality, efficiency, synergy capture


and cost control

Business Development Pursue opportunities that enhance growth


potential strategic and financially compelling, integrate rapidly
2014 Estimated Free Cash Flow ~$2bn
M&A - Priorities
Geographic Expansion
Supplement Brand Portfolio and Pipeline

Business Growth Plan


Commitment to Long-Term Earnings Growth
2014*

2015

2016

2017

35%+

10%+

10%+

10%+

NA Gx/ International
Pharma Principal Growth
Driver
-Specialty Brands Adding
Additional Value

Increasing Contribution of
Specialty Brands

Introduction of Biosimilar
Portfolio

Exceptional Performance of Global Operations Delivers on


Market Opportunities, Customer Service, Cost Control
* 2013 results are preliminary and unaudited and represent the high end of the 2013 forecast range for expected Non-GAAP EPS of $9.26 - $9.39 and Adjusted EBITDA of $2.22 - $2.24 billion provided on October 29, 2013. Reconciliations between
GAAP and Non-GAAP results/expectations can be found in the Actavis October 29, 2013 press release. On January 14, 2014, Actavis disclosed that 2013 results are anticipated to be modestly above this October 29, 2013 Non-GAAP forecast.

2014 Forecast GAAP to Non-GAAP Reconciliation


Forecast for Twelve Months
Ending December 31, 2014
Low

High

GAAP to Non-GAAP net income calculation


GAAP net income

456

544

Adjusted for:
Amortization

1,649

Global supply chain initiative


Acquisition and licensing charges
Interest accretion on contingent liability

1,649

40

40

341

341

20

20

Non-cash impairment charges and asset sales

Non-recurring (gains) losses and early retirement of debt

(50)

(50)

Legal settlements

Income taxes on items above

(245)

Adjusted Non-GAAP net income

(245)

2,212

2,300

Diluted earnings per share


Earnings per share - GAAP

2.60

3.10

Diluted earnings per share - Non-GAAP

12.60

13.10

Basic weighted average common shares outstanding

175.5

175.5

Diluted weighted average common shares outstanding

175.5

175.5

2014 Forecast GAAP to Non-GAAP Reconciliation


Forecast for Twelve Months
Ending December 31, 2014
Low
High

GAAP net income

456

544

Plus:
Interest expense

295
(2)

Interest income
Provision for income taxes
Depreciation (includes accelerated depreciation)
Amortization
EBITDA
Adjusted for:
Global supply chain initiative
Acquisition and licensing charges
Non-cash impairment charges and asset sales
Non-recurring (gains) losses and early retirement of debt
Legal settlements
Share-based compensation
Adjusted EBITDA

295
(2)

205

221

204

204

1,649
2,807

1,649
2,911

3
341
(50)
50
$

3,151

3
341
(50)
50
$

3,255

2014 Forecast GAAP to Non-GAAP Reconciliation


Reconciliation of Adjusted Gross Margin
Forecast for Twelve Months
Ending December 31, 2014
Low
High

Actavis Pharma GAAP Gross Margin %

59.8%

62.8%

0.5%

0.5%

Acquisition and licensing charges

2.7%

2.7%

Actavis Pharma Non-GAAP Gross Margin %

63.0%

66.0%

Adjusted for:
Global supply chain charges

2014 Forecast GAAP to Non-GAAP Reconciliation

Reconciliation of GAAP to Non-GAAP SG&A


Forecast for Twelve Months Ending
December 31, 2014
Low

Actavis Pharma GAAP SG&A % of Revenue

High

21.7%

23.2%

0.7%

0.7%

21.0%

22.5%

Adjusted for:
Acquisition and licensing charges
Actavis Pharma Non-GAAP SG&A % of Revenue

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