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NXF1/NXT1 transporter protein for mRNP and mode of interaction with FG-
nucleoporins
NXF1/NXT1 is a heterodimer that binds to parts of teh exon-junction
complexes in order to export mRNP.
hydrophobic regions of this heterodimer can reversibly bind to the FG-
nucleoporin domain and aid in mRNP diffusion through the NPC central
channel
miRNAs (micro RNA) and siRNAs (silencing RNA), properties and mode of
action (14)
miRNAs are micro RNAs that involve imperfect-base-pairing and inhibit
target mRNA translation
siRNAs are short interference RNAs that involve perfect-base-pairing,
cause mRNA degradation, defend again virus, and block excessive DNA
transposition
BOTH are short-single stranded RNAs that base pair to target RNAs