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  • Brochure Profhilo Vers2 HR

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    Brochure Profhilo Vers2 HR (1)

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    estetica

    Copyright:

    © All Rights Reserved
    Download as PDF or read online from Scribd
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    726 views20 pages

    Brochure Profhilo Vers2 HR

    Uploaded by

    togoreanunu
    estetica

    Copyright:

    © All Rights Reserved
    Download as PDF or read online from Scribd
    Flag for inappropriate content
    of 20
    IBSA Cory Institut Biochimique SA, founded in 1945, is the largest privately owned multinational pharmaceutical Ce mee “| firmly believe that the primary role of our company is to focus on the needs Cee eed see ee nn eee mech ee re eee ea ac ae Cot ec tose HUNDREDS OF S CTS AVAILABLE ENN eel Nc! COVERING IN MORE THAN PLANTS Paap eau ca) ET eee a CONTINUOUS R&D SCIENTIFIC INVESTMENTS KNOWLEDGE IS ONE 4 LEADIN aE Meet Py ea Prato eT OF THE paeorey ‘ART PRODUCTION TECHNOLOGICAL PLANTS DEVELOPMENTS FULL PRODUCTION PROCESS CONTROL HA raw material _ finished product The DERMOAESTHETIC AREA CIC ee ec) Pere errata and Aliaxin® based on the Hydrolift® OTe tap Tero ana rt Hydrolift® Action is an exp on Gerster Mn aie} preventing and fighting the aging process. veeee- IBSA's hyaluronic acid is an ultrapure grade HA, produced through a patented biofermentation process, of Streptococcus Zooepidemicus, which ranks worldwide as “TOP HIGH QUALITY” in terms: of purity and safety. PROFHILO BIOREMODELING ITALIAN LAUNCH February 2015, INTERNATIONAL PA tei] January 2016 ME pp mel Fey, ees 150,000 mf treatments performed to date December 2016 Available in 43 COUNTRIES 1, 2017 AMEC & AESTHETICS AWARDS Awwaitds 2 What’s new PROFHILO® STABILIZED HYBRID COOPERATIVE COMPLEXES IS THE FIRST PRODUCT DEVELOPED WITH NAHYCO* A UNIQUE AND INNOVATIVE THERMAL, PRODUCTION PROCESS PATENTED BY IBSA. How it works PROFHILO® promotes: MULTI-LEVEL) DYNAMIC) REMODELING LEADING TO A REMODELING OF THE EXTRACELLULAR: MATRIX IN TERMS OF ELASTICITY AND SUPPORT, PROMOTING AND MAINTAINING THE VIABILITY OF: FIBROBLASTS! KERATINOCYTES* ADIPOCYTES* Intended use TISSUE REMODELING AND. IMPROVEMENT IN SKIN LAXITY (FACE, NECK AND BODY). How to use 2 SESSIONS WITH A ONE MONTH INTERVAL. ALL AESTHETIC INJECTION TECHNIQUES ARE INDICATED IN THE SUPERFICIAL SUBCUTANEOUS LAYER, IBSA recommends, for the malar and submalar areas, the BAP Bio Aesthetic Points} techniaue with only 5 injection points on each side of the face. PROFHILO’ What's new Beginning with a simple mix: 82 mg of hyaluronic acil high molecular weight (1100-1400 kDa) 32 mg of hyaluronic acid low molecular weight (80-100 kDa) Production Thermal stabilization process (no chemical cross-linking ts use Process NAHYCO" HYBRID TECHNOLOGY Obtaining: PROFHILO’ ANEW TOOL with UNIQUE CHARACTERISTICS: vuvvVI9 bale TAM TT TT Ce NSC Cora Highly manageable* Extensive spreadabllity® Low viscosity* No BDDE or other chemical agents* Low inflammatory response" Thermally stabilized natural HA with a duration comparable to alow cross-linked gel PROFHILO’ How it works Invitro studies have shown that PROFHILO® improves the extracellular environment:'* > Maintaining suitable conditions for the viability of fibroblasts, keratinocytes and adipocytes. > Leading to a remodeling of the extracellular matrix in terms of elasticity and support. PROFHILO® SUPPORTS FIBROBLAST VIABILITY Control PROFHILO® 0.1% High molecular weight HA 0.1% Low molecular weight HA 0.1% (© Elastin monoclonal antibodies ‘© Phaloidin actin cytoskeleton filaments ing on fibroblasts (Human Dermal Fibroblasts, HDF)’ In vitro elastin immunofluorescence st PROFHILO® SUPPORTS ADIPOCYTE VIABILITY Commercially avaiable Control PROFHILO® 0.5% High molecular weight HA 0.5% — cross-linked HA dermal filer 0.5% © Fat deposits Couns of Bictknet In vitro Red Oil staining performed on Adipocyte Stem Cells in adipogenic medium, 14 days after incubation? An important characteristic due to the high cohesivity of PROFHILO® is, ts optimal tissue integration capacity." Notable for its ability to flow uniformly through entire anatomic units after injection and therefore homogeneously expanding fat compartments in challenging areas where even low viscosity filrs ‘can produce contour itnegularities.* ‘The IBSA GPS Scale is based on actual theological data: GPS PROFHILO®s behavior in the skin reflects a unique biophysical profile; particularly, a predominance Rena of fuidity over elasticity {tan delta > 1) which is not mT] present in other cross-linked gels.® —_ a cones Flow ur scuLpr bebleatensubrtet, . . PROFHILO’ Intended use TISSUE REMODELING AND IMPROVEMENT IN SKIN LAXITY FACE, NECK, BODY PROFHILO® intervenes: in the physiological in the dermal tissue in case of loss process of aging tissue, repair process, in cases or in presence of alterations of acne or scars compromised in elastic fibers adipose tissue and collagen PROFHILO’ How to use THANKS TO THE UNIQUE RHEOLOGICAL CHARACTERISTICS OF PROFHILO®, TISSUE REMODELING IS EASILY OBTAINED el Ae eel ee USING ALL AESTHETIC INJECTION TECHNIQUES, UR ele tia le Vee els ele nr) ele. aN REMODELING THE MALAR «SUBMALAR After 150,000 successful treatments to date (Dec, 2016) and as published in literature® , the BAP (Bio Aesthetic Points) technique, specifically developed for PROFHILO® by IBSA, is the most wide-spread, efficient and highly recommended protocol for treatment of the malar and submalar areas. Preferred by patients: kt Kk kkk tk Reduced number of Reduced number of injection Reduced or eliminated treatment sessions sites, therefore reduced downtime discomfort per session PROFHILO How to use BAP TECHNIQUE (BIO AESTHETIC POINTS) This technique was created for the lower third of the face due to its predisposition to dermal atrophy caused by the aging phenomena, © © © Kexo lentity the 5 BAP ject 0.2 ml per bolus injection sites on at the superfi each side of the face ‘subcutaneous layer ‘These 5 points identify the 5 anatomically receptive areas of the face with an absence of large vessels and nerve branches, therefore, minimizing the risks while maximizing the diffusion of the product in the malar and submalar areas. ZYGOMATIC PROTRUSION at least 2 om away fom the external comer ofthe eye NASAL BASE Za + draw a lino connecting tho nostril and tragus endicular line starting rom the pup * locate the injoction point a tha intorsaction of the 2 fino + draw a ps TRAGUS ‘om anterior to the bottom of the tragus CHIN + draw a vertcal ina in the canter ofthe chin + draw a perpenciclar line one third from the top ofthe vertical ine + from the point of intersection move 1.5 em towards the oral commissures MANDIBULAR ANGLE 1 em above the mansioular angle PROFHILO Courtesy te Erma Racha (Gogo Stan TECHNIQUE PRopucT ‘QuaNTiIy ‘TREATMENT SESSIONS ‘TREATMENT INTERVAL FREQUENCY 1 bolus + tanning 29G 13 mm needle 256 Somm cannula, 2mi per side 2 treatments weeks twice per year Protocols a ro TECHNIQUE 29613 mm needle propucr 1 miperside TREATMENT 2 treatments Nena Awocks FREQUENCY twice per year NECK 1 month aftr 2° treatment Corts te Pata Pec (a, a INNER ARM Basie TECHNIQUE 56 0 mm cannula BRERUCT per sie TREATMENT 2 vaatmonts TREATMENT a weeks REGUENCY twice peryear 7 point technique 296 13 mm needle PRODUCT 2miperside QUANTITY (02-0.3 mlfoolus) TREATMENT Esso. 2 treatments TREATMENT INTERVAL 3 weeks QUENCY 2-8 times per year ‘month ater 2 treatment HANDS Baseline ‘month ater 2° treatment cuts Geis PROFHILO’ Combined protocols PROFHILO® has significant potential for synergistic combination with conventionally cross-linked fillers to finesse volumetry results. Allaxiny PR/)FHIL© PRODUCT Aliaxin® EV PROFHILO® “TREATED Tew Mandibular contour Neck Fanning Fanning TECHNIQUE 226.60 mm cannula 256 50 mm cannula PRODUCT PeeRne 1 ml per side 2 ml per side ‘TREATWENT TREATEN 1 treatment 2 treatments “TREATENT. 4 weeks fortouch-up weeks INTERVAL ifnecessary FREQUENCY twice per year ifnecessary twice per year REDEFINITION OF MANDIBULAR CONTOUR AND NECK REMODELING Baseline 1 month ater 2° treatment Courtesy ot Prot Dal Cass an, a. snr Man Mla nd, PRODUCT ‘Aliaxin* GP PROFHILO® TREATED ones: = Subm Rea chook Malar Submatar Bolus deep on bone BaP TECHNIQUE 27G 19 mm needle 29G 13 mm needle. prosucr ppopucr 1 per sie 1 ml per sie TREATMENT TREATNEN 1 treatment treatments TREATWENT weeks for touch-up “awook INTERVAL ifnecessary weeks FREQUENCY twicepperyearifnecessary ‘twice peryear a FACIAL REMODELING AND CHEEKBONE ENHANCEMENT Baseline 1 month after 2 treatment Courts Sharon Dan. anh RESTORING SUBCUTANEOUS TISSUE DISORDERS PROFHILO® treatments with cannula for sulccutaneous recovery improve the quality of this layer, thus preparing the tissue for treatments with ALIAXIN®. Baseline 1 month ater 2° treatment Courtesy ot Pro Dal Cass an, a PROFHILO’ Results PROFHILO®'s tightening action has a positive effect on facial volume’ = %° [=

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