DRUG GENERAL ACTION SPECIFIC INDICATI CONTRAIND ADVERSE EFFECTS NURSING

NAME ACTION ON ICATION CONSIDERATI

ON
HYDROCOR SKIN AND MUCOUS MEMBRANE Short-acting Replaceme Hypersensitivit Body as a
TISONE AGENT; ANTIINFLAMMATORY; SYNTH synthetic nt therapy y to Whole: Hypersensitivity Establish
ETIC HORMONE; ADRENAL steroid with in glucocorticoid or anaphylactoid reactions; baseline
CORTICOSTEROIDS; GLUCOCORTICOI both adrenocorti s, idiopathic aggravation or masking of and
D; MINERALOCORTICOID glucocorticoi cal thrombocytope infections; malaise, weight continuin
d and insufficienc nic purpura, gain, obesity; urogenital g data on
mineralocort y; to reduce psychoses, urinary frequency and BP,
icoid serum acute urgency, enuresis increased or weight,
properties calcium in glomeruloneph decreased motility and fluid and
that affect hypercalce ritis, viral or number of sperm. electrolyt
nearly all mia, to bacterial CNS: Vertigo, headache, e
systems of suppress diseases of nystagmus, ataxia (rare), balance,
the body. undesirable skin, infections increased intracranial and
Antiinflam inflammato not controlled pressure with papilledema blood
matory ry or by antibiotics, (usually after discontinuation glucose.
(glucocortic immune active or latent of medication), mental
oid) responses, amebiasis, disturbances, aggravation of Lab
action: Stabi to produce hypercorticism preexisting psychiatric tests:
lizes temporary (Cushing's conditions, insomnia, anxiety, Periodic
leukocyte remission syndrome), mental confusion, serum
lysosomal in smallpox depression. electrolyt
membranes; nonadrenal vaccination or CV: Syncopal episodes, es blood
inhibits disease, and other thrombophlebitis, glucose,
phagocytosis to block immunologic thromboembolism or fat Hct and
and release ACTH procedures. embolism, palpitation, Hgb,
of allergic production Topical tachycardia, necrotizing platelet
substances; in steroids angiitis, CHF, hypertension count,
suppresses diagnostic contraindicate edema. and
fibroblast tests. Use d in presence Endocrine: Suppressed
formation as of varicella, linear growth in children, WBC
and collagen antiinflamm vaccinia, on decreased glucose tolerance; with
deposition; atory or surfaces with hyperglycemia, differenti
reduces immunosup compromised manifestations of latent al.
capillary pressive circulation, diabetes mellitus;
dilation and agent and in children hypocorticism; amenorrhea Monitor
permeability largely <2 y. Safe use and other menstrual for
; and replaced by during difficulties moonfacies. adverse
increases synthetic pregnancy GI: Cramping, bleeding. effects.
responsivene glucocortic (category C) or Special Senses: Posterior Older
ss of oids that lactation is not subcapsular cataracts adults
cardiovascul have established. (especially in children), and
ar system to minimal glaucoma, exophthalmos, patients
circulating mineralocor increased intraocular pressure with low
catecholami ticoid with optic nerve damage, serum
nes. activity. perforation of the globe, albumin
Immunosup fungal infection of the are
pressive cornea, decreased or blurred especiall
action: Mod vision. y
ifies immune Metabolic: Hypocalcemia; s susceptib
response to odium and fluid le to
various retention; hypokalemia and adverse
stimuli; hypokalemic alkalosis effects.
reduces decreased serum
antibody concentration of vitamins A Be alert
titers; and and C; hyperglycemia, to signs
suppresses hypernatremia. of
cell- GI: Nausea, increased hypocalc
mediated appetite, ulcerative emia
hypersensiti esophagitis, pancreatitis, (see
vity abdominal distention, peptic
reactions. ulcer with perforation and Appendi
Mineraloco hemorrhage, melena. x F).
rticoid Hematologic: Thrombocytop
action: Pro enia, polycythemia, Ophthal
motes ecchymoses. moscopi
sodium Musculoskeletal: Osteoporos c
retention, is, compression fractures, examinat
but under muscle wasting and ions are
certain weakness, tendon rupture, recomme
circumstance aseptic necrosis of femoral nded
s (e.g., and humeral heads. every 2
sodium Skin: Skin thinning and 3 mo,
loading), atrophy, acne, impaired especiall
enhances wound healing; petechiae, y if
sodium ecchymosis, easy bruising; patient is
excretion; suppression of skin test receiving
promotes reaction; hypopigmentation ophthalm
potassium or hyperpigmentation, ic steroid
excretion; hirsutism, acneiform therapy.
and eruptions, subcutaneous fat
increases atrophy; allergic dermatitis, Monitor
glomerular urticaria, angioneurotic for
filtration rate edema, increased sweating. persisten
(GFR). With parenteral therapy at IV t
Metabolic sitepain, irritation, necrosis, backache
action: Pro atrophy, sterile abscess; or chest
motes Charcot-like arthropathy pain;
hepatic following intraarticular use; compress
gluconeogen burning and tingling in ion and
esis, protein perineal area (after IV spontane
catabolism, injection).
redistributio ous
n of body fractures
fat, and of long
lipolysis. bones
and
vertebrae
present
hazards.

Monitor
for and
report
changes
in mood
and
behavior,
emotiona
l
instabilit
y, or
psychom
otor
activity,
especiall
y with
long-
term
therapy.

Be alert
 to
possibilit
y of
masked
infection
and
delayed
healing
(antiinfla
mmatory
and
immunos
uppressi
ve
actions).

Note:
Dose
adjustme
nt may
be
required
if patient
is
subjected
to severe
stress
(serious
infection
, surgery,
 or
injury).

Note:
Single
doses of
corticost
eroids or
use for a
short
period
(<1 wk)
do not
produce
withdraw
al
symptom
s when
discontin
ued,
even
with
moderate
ly large
doses.

BUDESONID HORMONE AND SYNTHETIC Glucocortico Treatment Hypersensitivit Body as a

E SUBSTITUTE; ADRENAL ids have a of allergic y to Whole: Arthralgia, fatigue, Monitor
CORTICOSTEROID; GLUCOCORTICOID; wide range and budesonide, fever, hyperkinesis, myalgia, closely
MINERALOCORTICOID of inhibitory perennial lactation. asthenia, paresthesia, tremor.
activities rhinitis, CNS: Dizziness, emotional for S&S
against maintain lability, facial edema, of
multiple cell remission nervousness, headache, agitat hypercor
types (e.g., in mild to ion, confusion, insomnia, ticism if
neutrophils, moderate drowsiness. concomit
macrophages Crohn's CV: Chest pain, ant doses
) and disease; hypertension, palpitations, of
mediators prophylaxis sinus tachycardia. ketocona
(e.g., for asthma. GI: Abdominal pain, zole or
histamine, dyspepsia, gastroenteritis, other
cytokines) oral candidiasis, xerostomia, CYP3A4
involved in diarrhea, nausea, vomiting, inhibitor
allergic and cramps. s (see
nonallergic/i Hematologic: Epistaxis. Drug
rritant- Metabolic: Hypokalemia, Interacti
mediated weight gain. ons) are
inflammatio Respiratory: Bronchospasms being
n. , infections, cough, rhinitis, given.
sinusitis, dyspnea,
hoarseness, wheezing. Monitor
Skin: Eczema, pruritus, patients
purpura, rash, alopecia. with
Special Senses: Contact moderate
dermatitis, reduced sense of to severe
smell, nasal pain. liver
Urogenital: Intermenstrual disease
bleeding, dysuria. for
increased
S&S of
hypercor
 ticism.

Lab
tests:
Periodic
serum
potassiu
m.