CHEMISTRY

FINAL
PROJECT

By:
Tanapat Worathumthongdee

1106

Present:
Patraphorn Sanguausat

Mahidol University International Demonstration School

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Butyl paraben

Purpose/Application

Butyl paraben is one of the most common that use to killed bacteria. It has been used

cosmetic products since the 1940s and in pharmaceutical products since 1924(5). In bury paraben

has really low toxicity which effective in antimicrobial properties. Nowadays, it has been used in

more than 20,000 cosmetic products such as eye shadow, facial moisturizer, anti-aging cream and

sunscreen(3). It also used in some food and drugs(2). However, it will be damage your face if you

used in the wrong amount. In most cosmetics butyl paraben is used at low levels, at a range from

0.01 to 0.3%(4).

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Chemical Properties:

Property Name Property Value

Molecular Weight 194.23 g/mol

Hydrogen Bond Donor Count 1

Hydrogen Bond Acceptor Count 3

Rotatable Bond Count 5

Complexity 171

Exact Mass 194.094 g/mol

Heavy atom Count 14

Isotope Atom Count 0

Covalently-Bonded Unit Count 1

Physical Property:

- Small, colourless crystals or powder

- Crystalline powder

- Finely divided solid

- Melting Point 154 to 156

- Solubility less than 1 mg/mL at 63 F

- Very slightly soluble in water

- Flash point at 181 deg C

- Vapour pressure at 25 deg C

- Stable under recommended storage conditions

- When heated to decomposition it emits acrid smoke and irritating fumes

Butyl paraben safety:

- acute chronic and subchronic toxicity studies

- carcinogenesis studies
- reproduction toxicity studies
- absorbing, metabolizing, and excreting studies
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 References

(1)Butyl 4-hydroxybenzoate. (n.d.). Retrieved May 22, 2017, from https://

pubchem.ncbi.nlm.nih.gov/compound/Butyl_4-hydroxybenzoate#section=MS-MS

(2)Center for Food Safety and Applied Nutrition. (n.d.). Selected Cosmetic Ingredients.
Retrieved May 23, 2017, from https://web.archive.org/web/20111030154312/http://www.fda.gov/
cosmetics/productandingredientsafety/selectedcosmeticingredients/ucm128042.htm

(3)ENO FINE CHEMICALS INDUSTRY LTD. Archived from the original on 2012-04-25.
Retrieved 2011-10-31.

(4)U.S. Food and Drug Administration. Archived from the original on 2011-10-30.
Retrieved 2011-10-31.

(5)UENO FINE CHEMICALS INDUSTRY LTD. Archived from the original on

2012-04-25. Retrieved 2011-10-31