Stress

Characteristic Depression PSQI

Gender

Male 33.13±11.056* 34.75±8.438 5.02±2.843

Female 31.09±10.045* 33.95±7.886 4.96±2.853

Age

<30 30.21±9.114* 34.05±8.389 4.59±2.410**

30-39 33.41±10.457* 35.05±8.387 5.22±2.776**

40-49 32.89±10.877* 34.32±8.085 4.98±2.937**

50-59 29.90±11.217* 33.36±7.695 4.51±2.637**

≥60 29.56±12.187* 30.43±5.740 8.75±5.497**

Educational Level

Ph.D. 32.83±11.834 33.44±7.923* 4.77±2.969

Master 31.98±9.903 34.17±7.921* 4.90±2.665

Bachelor 31.58±9.744 35.71±8.587* 5.44±2.855

Below Bachelor 30.75±9.239 38.82±9.022* 6.15±3.460

independent dependent variable beta R2

variable

stress(total effect) PSQI 0.1052*** 0.151***

stress depression 0.361*** 0.216***

depression PSQI 0.1142*** 0.235***

stress PSQI 0.064*** 0.235***

Stress Depressi sleep sleep subjectiv sleep sleep sleep daytime PSQI

on latency duration e sleep efficienc disturbanc medicatio dysfuncti total

quality y e n on score

Stress 1.00

Depression .483*** 1.00

 sleep 1.00
.265*** .303***
latency

sleep 1.00
.139** .177*** .210***
duration

subjective .377*** 1.00

.377*** .391*** .490***
sleep

quality

sleep .299*** 1.00

.131** .191*** .259*** .529***
efficiency

sleep 1.00
.158** .272*** .206*** .153** .243*** .138**
disturbance

sleep 1.00
.090* .097* .217*** .131** .219*** .139** .066
medication

daytime .547*** 1
.453*** .428*** .321*** .260*** .163*** .220*** .144**
dysfunction

PSQI .393*** .432*** .651*** .640*** 1.00

.790*** .579*** .391*** .316*** .708***

0.1053
stress PSQI

depression
0.3610

0.1142

stress 0.064
PSQI
Gene Locus Main effect(F) p-value Interaction p-value
effect(F)

CLOCK rs119325 6.407 0.012 0.350 0.705

sleep latency sleep subjective sleep sleep sleep daytime PSQI

duration sleep efficiency disturbance medication dysfunction

quality

rs11932595 AA .59±.757 .47±.662 1.08±.727 .23±.593 1.11±.316 .06±.383 1.45±.976 4.87±.022

Number 279 298 296 298 250 294 296 246

G/GA .82±.897 .84±.937 1.25±.667 .33±.648 1.16±.410 .13±.454 1.59±.891 6.07±2.972

Number 62 63 64 63 58 64 63 56

95%CI (-.448,-.015) (-.567,-176) (-.363,.025) (-.105,.084) (-.043,.049) (-.064,.055) (-.138,.134) (-1.197,.396)

P-value 0.036 0.000 0.160 0.088 0.378 0.244 0.302 0.003

Variable Category Number Percentage

Gender Male 291 50.2

Female 284 49.0

Missing data 5 0.9

Total 580 100

Age 20-29 91 15.7

30-39 222 38.3

40-49 151 26.0

50-59 102 17.6

60 or above 9 1.6

Missing data 5 0.9

Educational Background Ph. D, 197 34.0

Master 243 41.9

Bachelor 108 18.6

Below bachelor 21 3.6

Missing data 11 1.9

Position Administrative Staff 267 46.0

Faculty 274 47.2

Missing data 39 6.7

Title Professor 69 11.9

Associate Professor 120 20.7

Lecturer 69 11.9

Missing data 322 55.5

Physical Condition Excellent 170 29.3

Good 331 57.1

Average 62 10.7

Poor 3 0.5

Missing data 14 2.4

Mental Condition Excellent 222 38.3

Good 280 48.3

Average 42 7.2

Poor 5 0.9

Missing data 31 5.3