Pathophysiology of Appendicitis (Ruptured\)

Modifiable
Non-modifiable
Age: 11-20 yrs old  Diet: People whose diet is
Gender: male low in fiber and rich in refined
(male- female =2:1) carbohydrates
Hereditary: tumor formation in  Infections: Gastrointestinal
the opening of the appendix infections such as Amebiasis,
Bacterial Gastroenteritis,
Mumps

Obstruction of the appendix by

(fecalith (hardened stool), lymph
node, tumor, foreign objects)

Increase in pressure inside the

appendix lumen that result to
distention of appendix

Impaired venous return causing hyperemia (improper

O2, and nutrient supply)
Normal bacteria found in appendix begin to invade
(infect) the lining of the wall

Inflammatory Response – body response to the bacterial

invasion in the wall of appendix.
Increased Immune complex (disease plus antibody)
causes swelling of tissue resulting to inflammation of
appendix
S/S: abdominal pain, fever, and increase swelling of
appendix. Vomiting and loss of appetite

Appendectomy,
inflammation and infection spread pain medications
Pain- located @ RLQ, through the wall of the appendix
causing Guarding, causing death of tissue.
Vomiting & loss of The appendix ruptures due
appetite to increase pressure
(Perforation)

Appendectomy with
explore laparotomy
 Perforation (formation of a hole in an organ),
fecal materials exits to peritoneal cavity causing
formation of abscesses (periappendiceal abscess).
Infection can spread throughout the abdomen
(peritoneal cavity)

Bacterial invasion of Peritoneal Cavity causing

inflammation of the membrane that lines the
abdomen peritoneum (Peritonitis)
S/S: swelling of the abdomen, severe pain, and
weight loss

Sepsis (the condition or syndrome caused by the

presence of microorganisms or their toxins in the
tissue or the bloodstream )
Septecemia

IF NOT TREATED` IF TREATED

Septic Shock Strong antibiotic

S/S: Medication
• decrease Blood
pressure
Fluid Volume Replacement
• decrease blood
therapy
volume

COMA
RECOVERY

DEATH
LEGEND
AAA - Pathophysiology
AAA - Signs and symtoms
AAA - medical intervention
Bold letters (AAA, AAA, AAA)
- are pathophysiology and signs
and symtoms present to patient
- medical intervention done to
patient