Professional Documents
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Ike Dhiah R.
OVERVIEW
2
LIPID DIGESTION
3
STOMACH
4
EMULSIFICATION
IN SMALL INTESTINE
Emulsification
5
DEGRADATION BY
PANCREATIC ENZYME
Cholesterol Ester
TAG Degradation
Degradation
6
TAG DEGRADATION
7
CHOLESTEROL ESTER
DEGRADATION
Cholesterol esters are hydrolyzed by pancreatic
cholesterol ester hydrolase (cholesterol esterase) —-
produces cholesterol plus free fatty acids
8
PHOSPHOLIPID
DEGRADATION
Pancreatic juice is rich in the proenzyme of
phospholipase A2
9
CONTROL OF LIPID
DIGESTION
10
Free fatty acids, free cholesterol, and 2-
monoacylglycerol are the pri- mary products of
lipid digestion in the jejunum. These, plus bile
salts and fat-soluble vitamins (A, D, E, and K),
form mixed micelles
SECRETION OF CHYLOMICRONS
12
13
USE OF DIETARY LIPIDS BY TISSUE
Fate of
remaining The chylomicrons remnant binds
chylomicrons to receptors on the liver
14
REFERENCES
Ballantyne C. Clinical Lipidology: A Companion to
Braunwald Heart Disease. 2009. Saunders Elsevier