Journa!
*f (ltudlll",Dewlapme,nt & ftesenrch 2044
VACINAL TUMORS IN BI'TCHES
G.N.Purohitr, Arvincl Shtrmar, M.Garrrr and Srrnita Ranio
rt of Anirnal Reproducrion' Gynaecology and Obstctrics
\ttcrirrary and Animal Science, Bikanet (Rqi')- 314 001
sur$ically.
K ey wo rds : Bi tc h. libro ura. trnDsrn iss ib lc r.encrea l t tlluor. !'agi tl:r.
ph1'siological cvcnt for
is an
\ /aginal bleeding
V bitches itt procstrtts ltorvct'cr, lllalU'owllcrs
nray bc fii-uhtenecl and prcscllt thcir bitchcs to
thc clinician. for examitlfltion and thcrap,v. A
prolonged bleeding hou'et'er. warran(s
thorough eNamination as it mhy occru bccause
of growths, uterine pl'ohlems, problcms of
vestibulum or ut'inary bladdcr and grouoths'
\raginal tumors at'c dctccrcd in tlrc bitch
si-urrificanll;- tlorc clticlt lhan trvarian or ttlt-t-itrc
tunrors rvith nrost of thcni bcing Lrcnign likc
lciorrryomas, t'itrrornas and othcrs (Drcicr'
1998). Bitchcs investigatcd during
study had Browths s.hich were treated by
chcnrotherapy or su rgcry.
Mnteri'als and methods
Bitchcs prcsctttcd u'ith cornplaint ol'
hacmorhagic vaginal discharge (n= I 8) bctwecn
January 2003 to r\pril 2005 ro thc vctcrinat'y
olrsteuics arrd g1'naecology outdoor wete
included in tlris study. Thc breeds of bitchcs
I
Assisl aut Pt'o lcs-sol
i,Ass
istan r C i'tt:tccoloilrst. L RS- \{r || rbl
ABSTRACT
ol ltacntot'rllagic vagirtlll disclr;rlge ittld ot gt o$ llt
stoly-
tltcscbitclrcsrr'ct.cinditlcrcrrtpt'ocslrrti||stirgcsrv|tcr.cas.
pcs rvlticlt rverc diagnosrrd to be trarrsrtrissiblc venereal
lvith TVT u'cre treatcd with vincristirre sullatq 0'03i tug
wilh an tlne$enlfill recovery. Fibromns were rernovcd
includcd Cerntan Slrcplrcrd' Pomcranian'
Dobcrtunu. Grcat Darrc. l.abrador and Non-
Dcscript Bitchcs rvsrtc- c.ratnincd by spcctrlunt
and thosc shou'ing gl'owth cxtcrnally wcrc
a visually irrspccted. Swatrs were madc fl-om
anterior vagina fi:om bitches thar had no growths
and cytologicalcxamination was donc to givc
atJvicc on brecding attd,'or to kccp thc bitchcs
incloors to o\\'ncrs that did llol intcnd blccding
arrtJ ltacl blt-rtrght tritclrcs <.rrrl,r' hccattsc ol'f'car of
i'agrnal blccding. J'rattsrrissiblc Vcncrcal Tttmor
was diagnoscd by tvpicalcauliflowcr likc
(l-Vl')
thc pre scnt or nodular appeal'ancq arrd imprcssion stncars
revealing typical round cells'(Fig. I ).
Clrcnotherapy of TVT comptised of
adminisn'ation ofvincdstirre strlfatc @' 0.0?5 mE
kg B rvt. l\z or S(, rvcckly for 3-4 wccks
Srrlgrcal rcrnoval o{- ttrt'nors u'as dortc bv
rrpisioto$t,v urlder gencral anacsthcsia Ltsillg
kctantrnc and xylazirr cnlploying standald
tcchniques (Dreict, 1998)- Fibromas werc
d,iagnosod by histo-pathological cxamination
and appearancc of fibrous bands (Fig' 2).
I
Vetcri rut lr' (.)ll icer \1adl r I r Flrtr lts. (-'hottrtr
tAr.,s,',',' [)tolL'ssor L)cptt ol'\ctr Plttlrolo-lr
I I tltglr t Lidll i ptrr
.!ottrtxtI t,| ('ttttirre I)ctttIttltnt<'ttt <I llt"ttur<'It ]t)04

1- \'1 lCr ()1,)l lL)l t)!tf;rl tlt tr I lt r' 1 1g;11 | t Ot t t :l (-:l\t' t) |

T\,'T slro* ittg trrtrrrti ccllr

Fic -5: PhotrrurilL)h o1'Potlrcrllttrlttl bilcll shL)\\'inS I librotttlt

 Jourrurl o/ (lmirc f)evelopment tt Rewarch 2004
Ree.ult* **d discuss iom
Eight oftbe l8 bitches had somc orothervaginal
tumor. Bitchcs with proestral blccdinc tr,crc
advised for rnating. 'f V f was pr.cscnr in .i
Cerman Shcpherd bitchcs (Fig.3 ), I pomcr4nian
(Fig.a) and I non-dcscripr birch r,r,hcrcas.
tibromas wcre seenin I pomcranian, (Fig 5) |
non-descripf and I German Shepherd bitch.
TV f disappeared_in f bitches after Z-3 weeks
of therapy. Onc bitdfr u,as trcated for I rlorc
weck but it dicd duc ro cxtrcnc rvcakncss.
Surgical rcmoval offibr ornas showcd urrcvcntltrl
recovcty
Vhgpnal and v.estibularltrasses harc bcen known
clit or:al cnl arg6/sent,
tiofl. aridh.aeffiatoma
(Maryrthaiudom ard Johnston, l gg l The nr.osr
).
common clinical sign with vagjnal or vsty61.
neoplasia is vulvar dischar_ee or.sudtlcrr
appcarancc of a mass fi.om rhc vulva and occurs
commonly in old'agc scxuall.y.. inracr dogs
(Thaclrer ancl Bradlqy, 1983). Ncoplasia of
vagina aod vulva r:epreseflt 2.5 to J percent of
alleanin,e ttmdrs (Brodey nnd Roszel, lg67)-
TVT is known to be thc mo,sr fi'equently
repofted tumor in clogs ranuing fi'om ?-l-q39zo
olt thc- totarl nunttrc.r of tuntols irr canirrc
poprrfatiort (Garrdorla t't ul , l{)t)_1. ('haucllrar.r
and Rao. 1982). 1'\zT wcr.c diagrroscd b;. ttrcir.
typical cauliflower likc. peduncularccl qrowrh and
cyt o logical appearan cc as su ggesred prcvio u sl.v
(Tctrfa er nl..200.1). lvJost erf'rhe bitohes
re voulrbly ro the tf,eatment although
th valying degrccs of gasrrointestinal
problenu inc I uding vorni rin_u, sirnilar. to prcvio us
rcports( Boscos and Vervcridis. 2004: Calvct
et al., 1982r. Subcutaneous injccrions of
vincrisrine were given to bitches rvitl small sizcd
TVT bnt due to intense local roaction,
intravenous rou,te u'fls opterl in subsoquent
treahilcnts.
Fibrornas r,spsrredin this study responded woll
to srrr:gical gxcision. Studies bi, Thachei.and
Bradlcy, 198_t havc prcviously shown thar
cxccpt tbr I'V I most run.rr)r.s in brtchcs arc of
snrooth musclc or. librous tissuc or.i-uirr
(lciom.yonta. tibrr:nra) r,vhich rcspond u,cll to
sulgical cxcisiorr.
lt r.vas conclu.ded tlrar lritches with prolonged
i,aginal bleeding or dischar_ec ntust be'cxaurined
thoroughly for thc likcly prcscnce of rumors.
Refere n ces
Boscos. CM and Vcrvcridis. llN.(2004). CanirrcTVT:
Cliniccl lindings. diagnosis rld rreaitncnr
Sci.Proc WSVA-FECAVA-HVMS Wortrl
Clongrcsq, Rtrorles" Grese, (?):7jtt-76 t.
Brode1,. R:S and Rssr-ol. J.Fr( tg6?).Neoplasrns of tlle
cariinqntsrus, vagina aild.wlva, A clinieo-
pathologic sufve!' of ;,!)0 cases
J.Amer.Ver.l\,ted..{ssoc. | 5I:I21)4
Culver CA. LeiJ'er CE. \4cF-u,err ECj t lgrt? l. \iirrclisrinc
I
lbr t lrc I rc:rt rr riir r er l'Tr ;trrstr r issibltr \jurrcroa I
Tutnor irr tlrc dog. J Arner Vbt. i!,lccl Assoc.
I tt l(2): 163-164.
Chaudlmry,.f nncl Rao, M.R.K( l9tt2). Certliu canirre
rrcoplasrrrs cncourrtered in Andhra pr.adcsh,
lndian.Vet.J. 59: t 00-102.
l)reicr. H. K.( | 99ft )\irgina I discharge. Irr : (iornrarr.N.T
Ed. ('anine Medicinc and Thcrirpcurics
Bl;rckrrcll Scicrrce L K
(-r:trtdalllr.\ l.' . ( lrltrrlrlrr I,\ lrrrrl Sllrr rllr.R l)i l (J,) i j
()ccrrr rcttcc ol L-lnnnc tr-itrtstrrrssrblc \
L-llcrcitl
ttttnor attd r-r,alttirticrrt ol' l\vo tt.clttlucllts
I ndian Vct J. 70: tt.5.-t-.,i -S
r
iVlanothaiudonr.K and Joltnsron. S. D( ll)9 | ). Clinrcit I
approach to v.ilEli na livesti bular rrr a s ses i r r th e
bitqh. V'et. Clirr. Nonh Arner. Sllall Arrinr.
Prac.2l(3): 509-2 t.
Tella.iv1.A.. A.iala, O.O and Taiu,o, V O(2fi)4t.Conrgrlere
re-{rcssiou ol' transnrissiblc vcrrcreal
trrnror(l-\'T) irr Nigcriarr rrrorrglcl rlogs u,irlr
vincristine sul['ate cheruotlrcrap-v.
Afr.J. Bio.Med"Res. t(.1): | .13. | g.
"1
Tlracher C and Bradley. R.L.( lgli3). Vulvru and vagirnl
trulots irr the dog: a felrospec[iye stud1.. J
Arn. Ver, Med, Assoc. 183(6): 690.9?.