PRIMOS

product guide 2007

3D skin measuring solutions

- PRIMOS compact
- PRIMOS portable
- PRIMOS high resolution
- PRIMOS body
- software
- accessories
- services / training

Beauty ...
... is measurable
PRIMOS 3D optical measurement
… the first choice in 3D skin imaging solutions

Contents page

General information 2
PRIMOS compact portable 3

PRIMOS compact high resolution 7

PRIMOS compact 90 x 70, 120 x 160 9
PRIMOS body 11
Technology und Software 13
Software PRIMOS compact - Soft 14
Software PRIMOS body - Soft 16
Canfield’
Canfield’s Stereotactic face device 18
Service and support 19
Scientific Publication 20
Reference customer 23

Measuring capabilities 24

PRIMOS International
GFM products are available worldwide and used in 22 countries.
For questions regarding the usage of PRIMOS for future tasks in
your company or institute or pricing, feel free to contact us or our
authorized GFM international distributor at any time.

GFM 3D in vivo optical measurement of skin

www.gfmesstechnik.com
info@gfmesstechnik.com
PRIMOS 3D optical measurement
… quantitative skin measurement within
milliseconds

Dear professional

As a measuring method of the contact-

less working optical 3D measuring
device PRIMOS compact uses a digital
stripe projection based on micro mirrors
which allows for fast and highly precise
measuring data acquisition. An
assortment of different measuring
fields, realised by means of different
precise recording optics, ensures a
wide spectrum of measuring possib-
ilities with ranges up to micrometers. A
closed calibration concept, a calibration
method aligned to the measuring
system and the use of appropriate
adjusting pieces, guarantees comp- Measurement of crow's feet with
liance with the specified accuracies. PRIMOS compact

GFMesstechnik GmbH business areas include the development, manufacturing and

marketing of optical measuring and inspection systems as well as appropriate
measuring and evaluation software. GFMesstechnik measurement technology
stands for computer-assisted surface measuring systems and software based on
non-destructive optical measuring and testing methods. With PRIMOS skin devices it
is possible to record different sizes of skin surfaces fast and precisely.

Treated parts of the skin can be evaluated for all necessary parameters, e.g.
roughness, volumes and dimensions of wrinkles or scars, etc.. The software allows
retrieval of highly precise skin areas measured before and after a medical or
cosmetic treatment. Application fields are clinical applications, dermatology,
aesthetic medicine and biometry.
PRIMOS compact portable

... simple, flexible 3D measuring

The PRIMOS portable device is the system of choice for everyone who requires
flexibility, yet would still enjoy measuring many different areas of the body. The
compact design of the system and the simple operation grant such flexibility
without a complex tripod. The recording speed coupled with robust measuring
modes grants reliable, stable measurements irrespective of movements from user
or patient.

The only worldwide, hand-guided 3D in vivo skin measuring system based on

digital strip projection combined a high precise 3D skin measurements with
maximum flexibility. The speed of under 70ms for the measuring data admission
provide perfect results of measurement.

Key Features

• Flexible one in vivo

measurements
• Hand-guided 3D sensor
• Integrated source of light
• Easy operation with
mobile PC
• Current software-Version
5,2 with overlay and
Matchingfunction
• 3D photographs with
color texture

technical data

Measuring field : [mm²] 40 x 30

Lateral resolution : [µm] 63
Height resolution : [µm] ≥ 4
GFM PRIMOS compact portable is Accuracy: [µm] ≥ 6
a flexible hand-held device Data acquisition time: [ms] < 70
PRIMOS compact portable
... Analyse of the skin surface with a measuring field
of 40 x 30mm²

Application: Measurement and evaluation from eye

wrinkles to the analysis of anti- Aging products

Data acquisition

With PRIMOS compact it is possible to seize the color texture to to combine

and represent with the three-dimensional data record. The 3D color
representations is particularly suitable for your marketing of projects,
presentations and studies.

3D data combined with colour texture 2D profile selection

Evaluation on the basis profile lines

In the filtered picture as many lines as desired, can be inserted and be represented
in a profile in the sectional view. On the sectional view there can be numerous
geometrical measurements such as depth, distance, radius etc. The Matching
function makes the direct comparison possible for two or more data records.

3D data before & after comparison the Difference measurement

Matching at the profil selection
PRIMOS compact portable
... Analyse of the skin surface with a measuring field
of 40 x 30mm²

Application: Evaluation of wrinkles volumes

Volume measurement of eye folds

The volume determination of eye folds is for

many users a principal purpose, in order to
better note significant changes and retain
statistically precise representations. For
these ranges, those which will be included
into the computation are marked. As result of
the measurements you will, in the end,
receive the volume of the marked folds.
Colour coded 3D elevator picture after the
filtering

Automatic computation of scars and skin

knots

For individual, and multiple evaluation of

scars
or skin knots in the measuring field, you can
use an automatic evaluation algorithm. This
function recognizes all maxima or depth and
calculated volume, extent and max. height
(depth) independently. The measurement
3D representation with colour texture
results are then displayed in tabular form.

Index of the results of measurement

Automatic detektion of a fire scar
 PRIMOS compact portable

... various combination options

GFM PRIMOS Sensor combined with Canfield’s Stereotactic

Tripod for simplified positioning

The 3D sensor, and its specially constructed tripod, can be installed with minimal
handling. With the help of this stand, special photographs can be accomplished and
the face range more easily and more exactly acquired, in the shortest time possible.
The positioning of the sensor is easily maneuvered so that the test person can relax
into the tripod which can rotate around 150 °.

Recommended applications for

PRIMOS compact portable

üWrinkles
üNaevi, Neurofibroma, Acne
ü Wounds
üScars
üMelanoma (Topography)
PRIMOS compact high resolution

... 3D measurements for highest requirements

The PRIMOS compact high resolution measuring system was developed, in order to
meet the highest requirements for research and science. The skin, as a mirror of
the soul and health, takes a key role in the evaluation of pharmaceutical and
cosmetic products. The increasing number of these products requires objective
valuation criteria and measuring instruments.

Key Features
• Most recommended
device in skin
research
• Measurements of
larger structure and
roughness with only
1 device!
• Latest software
PRIMOS 5.3 incl.
matching function
for treatment control GFM PRIMOS Sensor combined with
Canfield’s Stereotactic face device

PRIMOS compact high resolution combines the advantages of a large measuring

field with a high resolution without compromises! It is a recommended instrument
for the user to obtain: skin textures, as well as roughness and smoothness, larger
structures, such as crows feet or wounds, to measure and/or scars precisely and
fast.

technical data

Measuring field : [mm²] 24 x 15

Measuring points : 1000 x 800
Lateral resolution : [µm] 24
Height resolution : [µm] ≥ 2
Accuracy: [µm] ≥ 3
Data acquisition time: [ms] <70
PRIMOS compact high resolution

... high end research skin measurement

Applications: Analysis of crow’s feet and fine lines,

3D image captured with PRIMOS compact high resolution

Source 3D image of the Color coded 3D profile

Source 3D image of an
skin micro profile after filtering with cut
area around the eye
line

Cross section with Automatic evaluation of star or surface roughness

depth measurement parameters such as Ra, Rz,… Sa, Sz,…

Recommended applications for

PRIMOS high resolution
üRoughness
üFine lines
üWrinkles
üWounds, Scars
üReplica
PRIMOS compact
... measuring field: 90 x 70 mm² and 160 x 120 mm²

The PRIMOS compact large field systems are ideal for the investigation
and documentation of skin macrostructures such as nasiolabial folds,
large scars and wounds, cellulite and parts of the face and body such
as hands, feet or breast.
In combination with different types of tripods you will be able to perform
measurements over the entire body. The PRIMOS system is equipped
with a fast color camera which provides fast imaging and perfect color
textures.

Key Features
• Large field 3D
measurements
• Use with mobile PC
possible
• Latest software
PRIMOS 5.05
• Color Firewire
camera

technical data

Measuring field : [mm² ] 90 x 70 [mm²] 160 x 120

Measuring points : 640 x 480 640 x 480

Lateral resolution : [µm] 140 [µm] 250
Height resolution : [µm] ≥ 9 [µm] ≥ 12
Accuracy: [µm] ≥ 14 [µm] ≥ 25
Data acquisition time: [ms] <70 [ms] <70
 PRIMOS compact
... measuring field: 90 x 70 mm² and 160 x 120 mm²

Applications

Geometric measurements on
3D point cloud with
the cross section
cut line from
forehead to the lips

Measurement the thigh for the objective Evaluation of the skin surface
evaluation of Cellulite at the 3D elevation picture

Recommended applications for

PRIMOS 90x70 mm² and 160x120 mm²
üParts of the Face
üLarge wounds and scars
üNasiolabial fold
üCellulite
üBreast
üHand, feet
PRIMOS body

Fast 3D measurement supplemented by acquisition of colour texture in

a brilliant 6.1 Mega pixel quality. The large field measuring system
PRIMOS body is the recommended device for precise face and body
measurements. You can capture a complete face with only
1 measurement in 140 ms! The use of newest technologies supply
objective measuring results for treatment control and many other
applications. The exported polygon data allows direct import into
production line for perfect fitting items like masks or artificial
replacements. The software supplies all essential functions for the
evaluation and presentation of 2D and 3D measuring data.
Key Features
• Large field 3D
measurements
• 6.1 M-Pixel color
texture
• Fast and easy face
measurement
• Easy portable
• Latest software
PRIMOS body 6.2 The Sensor includes the stripe projector
incl. Matching function and three fast cameras for the 3D image
for teatment control and the color textures

• *.stl data export

Technical data

Measuring field : [mm²] 300 x 300

Measuring points : 1200 x 1000
Lateral resolution : [µm] 500
Height resolution : [µm] ≥ 30
Simple handling
Accuracy: [µm] ≥ 30
Data acquisition time: [ms] < 140
PRIMOS body

Applications

3D picture with 3D point cloud Geometrical measurements of

high resolution of the face the profile section
color texture

Further possibilities for the use of a PRIMOS body measurement system. Full
digitized doll in two views and a human leg with feet.

Recommended applications for PRIMOS body

üComplete Face
üParts of the body (belly, arm, leg…)
üCellulite
üBreast
PRIMOS compact
... technology & software

Two functions integrated in the standard software help you with regaining and
comparison of the measured skin areas.

Overlay and live picture Overlay and live picture after adjustment

Reproducible retakes succeed perfectly with the integrated OVERLAY function. A

camera picture of the last shoot is faded in transparency background of the live
picture and you can align the sensor millimeter-exactly. A project cross-line screen
guarantees the correct focus to the item being tested.

The fine tuning takes over the matching

function of the software. In addition the
reference data record and a measuring data
set are loaded. The measuring data set is
aligned in such a way that the measuring area
agrees accurately with the reference. Now, i t
is possible to compare the data records with
another and to determine differences in the
skin structure.
3D data before & after
comparison after the Matching
PRIMOS compact - Soft
... complete software solution for skin measurement and
evaluation in cosmetics and medicine

Application

• Software complete solution for

the use in cosmetics research,
industry and in medicine

• Measurement of skin surfaces

and replica

Features

• Fast evaluation algorithms

Skin measurement in video real time is • Employed in adapted to the skin

unthinkable without the use of sophisticated measurement systems
measurement and evaluation software. Only
• Clearly arranged 2D and 3D
trough fast processing and user-oriented representation of results
presentation of results, measured data are
transformed into relevant information. • Integration of special
evaluation algorithms for skin
Our measurement system and evaluation measurement, e. g. star
software are developed completely in roughness, matching of skin
Germany by GFM, ensuring a maximum areas etc.
efficiency in the collection and evaluation of • Comprehensive interfaces for
measuring data. export and import data

From a close and continuing cooperation with
users, a software solution results offers results
which are optimally adapted to the
requirements of daily use in the field of
cosmetics industry and medicine, e.g.
dermatology.
• Database functionality for the
storage and evaluation of large
amounts of data or serial
measurement
• Rich set of functions for 2D and
3D data evaluation

Contained in the PRIMOS software package Advantages

are all necessary functions for the measuring
of skin surfaces, including the determination of • Efficient through adaptation to the
measurement system used
2D/3D roughness parameters and of star and
surface roughness. • Large set of functions and options
Also included in the software are geometric • Customer specific extensions can
measurement options like the measurement of be realized fast
distances, radii, angles and volumes, e.g., of
skin wrinkles.
PRIMOS compact - Soft

Technical data
Measuring systems
• Primos optical measurement devices for in vivo skin
measuring or skin replica measuring
• Third part measuring devices with special data interface

Supported measuring modes

• In vivo measurement of skin
• High precision fast replica measurement

Evaluation functionality
• Basic filtering
Skin roughness
(e.g. Mean, Gauss, Media, Fourier)
• Polynomial filtering from degree 1to 8
• Robust high pass filtering
• Line roughness
(e.g. Ra, Rz, Rq, Rmax, R3zmax, Rp, Rk, Riso, Rc, Sm, W t)
• Star roughness for 3 up to 16 angle positions
(e.g. Ra, Rz, Rq, Rmax, R3zmax, Rp, Rk, Riso, Rc, Sm, W t)
• Surface roughness
Wrinkles, 3D color
(e.g. Sa, Sz, Sq, Smax, S3zmax, Sp, Sk, Siso, Sc)
coded visualization
• Matching of skin areas
(3D matching, compensation of stretching, visualization of
deviations)
• Measurement of skin series
• Database functionality

Data representation
• Color coded high picture with editable scale
• Sectional view with interactive measuring and labeling
• 3D Visualisation of skin topography
(interactive 3D function for rotating, orientation, zoom,
Wound and scar scaling, etc.)
measuring • Graphical and numerical prints of measuring results

Data interface
• Import filter
(e.g. ASCII, stl)
• Export filter
(e.g. ASCII, BMP, JPG, TXT, WMF, SDF, FD3)

Operating system
Matching of skin areas • Windows 2000 / XP
PRIMOS compact body - Soft
... evaluation software for professional face and body
measurements

Applications

• Complete software solution for

measurement and evaluation

• 3D measurements of faces and

parts of the body specialized for
the use in the plastic surgery and
medicine

Characteristics
3D pictures with color texture in the
evaluation area before matching
• Quick evaluation algorithms

• Results are presented in 2D and

3D shape

• Matching function to define

differences after a cosmetic or
surgery treatment

• Extensive interfaces to the import

and export of data like ASCII *.stl –
data for direct import into
After the matching the right image production machinery
shows the differences
• Data base functionality for the
storage and evaluation of larger
data sets or of series
measurements

• Various possibilities for the

evaluation of the data and
determinations of geometry such
as lengths, radii, angles and
volumes

Cross section picture along the cut

line of both images shown in the
picture above.
PRIMOS compact body - Soft
... evaluation software for professional face and body
measurements

Difference picture with marked areas of Automatic evaluation of the difference

interest around & near the lips volume, surface and average height

Measuring system Data Interfaces

PRIMOS body face and body Import filter

measuring system for the fast in vivo ( ASCII, BMP, SDF, STL)
measurement Export filter
( ASCII, BMP, SDF, STL)
Result representation
2D and 3D representation System requirements
Convert in CAD-readable data Microsoft Windows 9x or NT 4.0
(polygon) Pentium III >600 MHz, 128MB RAM
point clouds
3D images

3D-shape of a chest range with color texture Determination of geometrical dimensions of the
at the profile section with a cut line chest along the cut line
Canfield’
s Stereotactic Face Device

Precision stand for face positioning with the 3D in vivo skin

measurement

Application
• Measurement of wrinkles, scars, wounds and all topographical
characteristics within the face range in combination with a PRIMOS
compact sensor from 13x18mm² - 120 x 160mm²

Characteristics
• Easily positioning of the sensor in X, Y and Z direction
• Angle exact turn of the chin and front mounting plate to the sensor
• Firm footing by suction feet and balanced emphasis

Advantages
• Accuracy and reproducible positioning of the sensor
• Pixel-exact area regaining for process controls of medical and
cosmetic treatments
• Simple calibration of the sensor by an easily mountable plate for
normal calibration
GFMesstechnik
... service & support

User Training

The claim of GFMesstechnik is to supply the best technique in optical 3D

measurement. Therefore we are always endeavored to improve and develop
our products.
To reach optimal results with its PRIMOS measuring instrument it will be
necessary to work with the optimal system but also to know about the handling
of these systems. Therefore we recommend to make use of our offer for user
training.
GFM support team employees will complete the installation of your measuring
instrument in your office, and they will train your staff in the handling of the
equipment and in the evaluation of the raised data.
The recommendation is to get a one day training session after installation and
another one, or two, day training session approximately 8 weeks after
installation.

The user training contains:

• Hardware installation

• Ancillary conditions for the measurement

• Software handling

• Measurement options

• 3D presentation and result presentation

• Saving results

• Volumetric measurement

• Roughness evaluation and parameter

• Using of database

• Appraisal of results
Scientific publications
... PRIMOS measuring devices*

• Lasers in Surgery and Medicine

36:85-91 (2205)
Clinical trial of a Novel Non-Thermal LED Array for Reversal of
Photoaging: Clinical, Histologic and Surface Profilometrie results
Robert A. Weiss, David H. McDaniel, Roy G Geronemus, Margaret A. Weiss

• Skin Research and Technology

2004 Nov;10(4):207 - 14
In vivo determination of skin surface topography using an optical 3D
device.
Jacobi U; Chen M; Frankowski G; Sinkgraven R; Hund M; Rzany B; Sterry W;
Lademann J

• Medical Laser Application

Dec. 2004
Subjective Evaluation and Objective Measurement Methods in Cosmetic
Dermatology
Jean Luc Levy, Frederic Pons, Lise Agopian, and Regis Besson

• Dermatol. Surgery
2004; 30: 152 – 157
Comparsion of a 1450-nm Diode Laser and a 1320-nm Nd:YAG Laser in
the Treatment of Atrophic Facial Scars: A Prospective Clinical and
Histologic Study
Tanzi E. L., Alster T.S.

• Dermatol. Surgery
March 2002; 28(3):199-204
3D in-vivo optical skin imaging for topographical quantitative
assessment of non-ablative laser technology
Friedman PM, Skover GR, Payonk G, Kauvar AN, Geronemus RG

• Journal of Wound Care

VOL 12, NO 9, Page 362, October 2003
PRIMOS: an optical system that produces three-dimensional
measurements of skin surfaces.
Roques C, Teot L, Frasson N, Meaume S.

* This list is not exhaustive- please find more links at our webside
 Reference Customer list

• Avon, Suffern/ USA •Laser & Skin Surgery Center, New York/ USA

• Beiersdorf AG, Hamburg • Light Bioscience, Virginia Beach/ USA

• BioSkin GmbH, Hamburg • L'Oreal/ Cosmair Cosmetics Corp., Clark/ USA

• Candela Corp., Wayland/ USA • Lumenis, Israel/ USA

• Cetco Lima/ Peru • Massachusetts General Hospital, Boston/ USA

• Cognis, Pulnoy/ France • Neutrogena Corp., Los Angeles/ USA

• Colgate-Palmolive Company, • Nippon Lever/ Japan

• Consumer Product Testing Co., • O Boticario, San Jose dos Pinhas/ Brazil

• Derma Laser Inc., Montreal • Pfizer Inc., Morris Plaints/ USA

• DermaConsult, Alfter • Philips Personal Care Institute,

• Dermatest, Muenster • PowerPaper, Israel

• DermaTronnier, Witten • Procter & Gamble Company, Egham/ UK

• Dermscan, Lyon/ France • Procter & Gamble Company, Piscara/ Italy

• Dr. Prakash, London/ UK • Procter & Gamble Far East Inc., Kobe/ Japan

• Dr. Zelickson, Edina/ USA • proDERM GmbH, Hamburg

• Ellead Seoul/ Korea • Renovo Ltd., Manchester/ UK

• fzmb e.V., Bad Langensalza • Rosenparkklinik, Darmstadt

• Gilette UK • Ruhr University of Bochum

• Henkel KGaA, Duesseldorf • Skin Biology Center, Hamburg

• Hoffman LaRoche AG, Basel/ •Technical University of Munich,

• Hospital Neukoelln, Berlin •Unilever Thailand

• Institute of Cancer Research, •Unilever, Edgewater/ USA

• Johnson & Johnson CI-RoC •Unilever UK

• Johnson & Johnson Phils. Inc., •Unilever Shanhai / China

•Johnson & Johnson, Skillman •Universities: Ulm, Luebeck

• Kanebo/ Japan •University Hospital Charité, Berlin

• Kose/ Japan •University of Michigan, Ann Habor/ USA

• University of Seoul/ Korea

* This list is not exhaustive

 Reference Customer - Statements

It is the fourth year of our co-operation. In the past 3 years GFM

helped us - owing to good services to master our challenges
gradually. PRIMOS 3D-Messgeräte - with the ingenious Design
and the exact results of measurement - make us possible to win
more information about product effects on the skin. Measuring
e.g. of folds, fine lines, pores and skin roughness supports our
marketing in singular way and leaves our dreams becomes true. We hope for
more technical communication between our customers, in order to realize further
improvements.
Recommended by: Mrs. Cissy Li, Unilever Research China:

After one year experience with the PRIMOS system, we

estimate the possibility in vivo measurement and
evaluation of eye folds in our application fields anti- aging
and sun protection. The system is very user friendly and
is characterised by a good performance during the measurements. At most we
estimate the effective technical support and the comprehensive support. Inquiries
were always answered within shortest time satisfyingly.
Recommended by: Ms. Dr. Olivier DOUCET, Director of Skin Research and Skin
Pharmacology Team, LANCASTER COTY:

The Derma Consult GmbH, Institut specialized in testing of

cosmetic, cosmetic raw materials, cleaning products and
Dermatika, uses the PRIMOS Compact of systems in the
context of effectiveness investigations from Cosmetics to the
measurement of the skin roughness and wrinkles depth both in vivo, and for the
measurement of skin castings. This flexibility in combination with the high measuring
accuracy and minimum gate times convinced us.
Recommended by: Ms. Boris Nissen, Derma Consult GmbH:
 PRIMOS 3D measuring
... recommended system measuring capabilities

PRMOS
13x18 mm² 40x30 mm² 16x26 mm² 90x70 mm² 160x120 mm²
body

Skin
Roughness
YES YES
and fine
lines

Wrinkle YES YES

Wound YES YES YES

Scar YES YES YES

Lesion /
YES YES YES
Mole

Nasolabial
YES YES
Fold

Cellulite YES YES

Breast YES YES YES

Face YES

Replica YES YES