An Interview with Louis R.

Bucalo
Name: Louis R. Bucalo.
Title: CEO, Chairman, President.
Company: Titan Pharmaceuticals.
Background: After receiving his medical degree from Stanford
University, Louis R. Bucalo began to work for early-stage biotech
company Triton, now Berlex, as associate director of clinical research
between 1987 and 1990. Louis R. Bucalo went on to work for South San
Francisco-based Genentech as associate director for clinical research
from 1990 to 1992. Louis Bucalo founded Titan in 1993.
Education: Mr. Bucalo earned his Bachelor of science degree in
biochemistry from Harvard University; M.D., Stanford University.
Residence: San Francisco.
The essential business philosophy of Louis R. Bucalo: Maximize the
hits. In Major League Baseball, if you only hit 15 percent of the time,
you're cut.
If you hit 35 percent of the time, you're in the Hall of Fame.
Best way to keep competitive edge: Develop leading edge science and
develop practical solutions.
Guiding principle: Choose inspiring goals, accumulate resources and
set specific objectives.
Yardstick of success: People living longer with better quality of life
because of therapies developed by Titan.
Goal yet to be achieved: We want people all over the world benefiting
from our therapies.

JUDGMENT CALLS
Best business decision Louis Bucalo made: Forming global alliances
with big pharmaceutical companies like Novartis and Schering AG that
allowed us to grow. It was important because it multiplied our
resources for our development programs.
Worst business decision: Not having several investment banking
partners in the first year of operations. We had only one, and that
slowed us down.
Toughest business decision: Passing on some exciting tech on bone
marrow technology a few years ago. It was tough but right. The science
was very exciting, but the development costs were very high.
Biggest missed opportunity: When I was at Genentech, I approached
business development and advised them to spinout a product
opportunity that could be better exploited, but the company wasn't
ready to do that at the time. Later, they did.
Mentor: Sid Braginsky, founder of Olympus Opticals U.S. He was an
inspiring example. He started with nothing and established a
substantial company.
Word that best describes you: Relentless.

TRUE CONFESSIONS
Like best about job: Working with some of the best medical scientists
and doctors in the world.
Like least about job: Not being able to pursue all the treatments we're
interested in. In our game, prioritization is essential.
Pet peeve: Wasted time whether through inefficient meetings or
unnecessary emails.
Most important lesson learned: Get all the data and follow your
instincts.
Person most interested in meeting: Leonardo da Vinci.
Most-respected competitor: Genentech. They were the first.
Three greatest passions: Science, family, music - I play keyboards and
guitar.
First choice for a new career: Owning and running a top football or
baseball team.
Favorite quote: "Don't go around saying the world owes you a living,
the world owes you nothing. It was here first" - Mark Twain
Favorite causes: Freedom, Leukemia Society, Breast Cancer Society.
Most influential book: "Autobiography of Benjamin Franklin."
Favorite status symbol: Titan gave me a plaque last year
commemorating the treatment of our first patient.
Favorite movie: "Cinema Paradiso."
Favorite restaurant: Pane e Vino, in San Francisco.
Favorite vacation spot: Capri or the Italian Riviera.
Favorite way to spend free time: Thinking of new business ideas.

Louis R. Bucalo: An Interview with Louis R. Bucalo