FUROSEMIDE

Brand Name: Lasix Dosage: 40mg q8

Drug Class: Loop Diuretics Route of Administration: IV
Pregnancy Category: C; D if used for PIH

MODE OF INDICATIONS CONTRA- ADVERSE DRUG INTERACTION HEALTH TEACHING/

ACTION INDICATIONS REACTION NURSING
CONSIDERATION
Inhibits • Edema associated • Anuria • Symptomatic Drug to Drug • Record input and output
reabsorption of with heart failure, • Hepatic coma and hypotension • Increased risk of cardiac cc per cc
sodium and cirrhosis, renal pre-coma • Dehydration arrhythmias with cardiac • Weigh yourself on a
chloride from the disease • Severe hypokalemia • Hypokelemia, glycosides regular basis
proximal and • Acute pulmonary and/or hyponatremia hyponatremia, • Decreased absorption with • Note that blood glucose
distal tubules and edema • Hypovolemia with or metabolic phenytoin level s may temporarily
ascending limb • Hypertension without hypotension acidosis • Decreased natriuretic and elevated in patients with
of loop and antihypertensive effects diabetes after starting
Henle, leading to with indomethacin, this drug
a sodium-rich ibuprofen, NSAIDs • Avoid rapid position
diuresis • May reduce effect of changes, heavy activities,
insulin or oral antidiabetic and sun exposure
because blood glucose • Report loss or gain of
level can become elevated more than 3 pounds/day,
swelling in your ankles or
fingers, and unusual
bleeding or bruising
 CEFUROXIME
Brand Name: Zegen Dosage: 750mg q8
Drug Class: Antibiotic, Cephalosporin (2nd Generation) Route of Administration: IV
Pregnancy Category: B

MODE OF INDICATIONS CONTRA- ADVERSE DRUG HEALTH

ACTION INDICATIONS REACTION INTERACTION TEACHING/
NURSING
CONSIDERATION
Bactericidal: • Lower respiratory Contraindicated • Thrombophlebitis Drug to Drug • Give oral drug with
inhibits synthesis infection and with allergy to • Pruritus, urticaria • Increased food to reduce GI
of bacterial cell bronchitis cephalosporin or • +Coomb’s test nephrotoxicity with upset.
wall, causing cell • Pharyngitis, penicillin • Diarrhea, nausea, aminoglycosides • Swallow tablets
death Tonsillitis, sinusitis pseudomembranous • Increased bleeding whole; Do not crash
• Gonorrhea colitis effect with oral them
• Meningitis • Decrease Hb and anticoagulants • Take full course of
• Otitis media Hct, transient • Risk of disulfiram- therapy even if you
• Peritonitis increase in liver like reaction with are feeling better
• Surgical infection enzymes alcohol • You may experience
• UTI • Elevation in serum Drug-lab test these side effects:
creatinine and BUN • Possibility of false stomach upset or
results on test of diarrhea
urine glucose using
Benedict’s solution
 TRIMETAZIDINE
Brand Name: Tazz Dosage: 35mg tab BID
Drug Class: Anti-anginal Route of Administration: Oral
Pregnancy Category: C

MODE OF INDICATIONS CONTRA- ADVERSE DRUG INTERACTION HEALTH

ACTION INDICATIONS REACTION TEACHING/
NURSING
CONSIDERATION
Bactericidal: • Long term Known • Gastric discomfort No known drug interaction • Report irregular
inhibits synthesis treatment of hypersensitivity to • Nausea heartbeat, shortness of
of bacterial cell coronary Trimetazidine • Headache breathing, swelling of
wall, causing cell insufficiency hydrochloride and • Vertigo hands and feet,
death • Angina pectoris can therefore be pronounced dizziness,
• Ischemia of prescribed even and constipation
nuero-sensorial when other • Should be taken after
tissues in antianginal agents meal
Meniere’s disease are contraindicated. • Protect drug from light
and moisture
 CLARITHROMYCIN
Brand Name: Clariget Dosage: 500mg 1 tab BID
Drug Class: macrolide antibiotic Route of Administration: Oral
Pregnancy Category: C

MODE OF INDICATIONS CONTRA- ADVERSE DRUG INTERACTION HEALTH

ACTION INDICATIONS REACTION TEACHING/
NURSING
CONSIDERATION
Inhibits protein • Treatment of Hypersensitivity to • Nausea Drug to Drug • Can be administered
synthesis in upper and lower clarithromycin, • Dyspepsia Increased serum levels and without regards to meal
susceptible respiratory erythromycin or • Abdominal pain effects of carbamazepine, • Do not drink grape juice
bacteria, causing infection any microlide • Vomiting and theophylline, lovastatin, while taking this drug
cell death • Acute otitis media antibiotic. diarrhea phenytion • Report severe or watery
• Skin and soft Patients receiving • Headache diarrhea, severe nausea
tissue infection terfenadine therapy • Taste pervesion
Drug to Food or vomiting, rash or
with pre-existing • Food decreases the rte of itching
cardiac • Transient
absorption of
abnormalities or elevation of liver
clarithromycin but does not
electrolyte enzyme
alter effectiveness
disturbances • Decreased metabolism and
risk of toxic effects if
combined with grapefruit
juice, avoid this
combination
 METOPROLOL
Brand Name: Neobloc Dosage: 50mg ½ tab OD
Drug Class: Antihypertensive Route of Administration: Oral
Pregnancy Category: C

MODE OF INDICATIONS CONTRA- ADVERSE DRUG INTERACTION HEALTH

ACTION INDICATIONS REACTION TEACHING/
NURSING
CONSIDERATION
Selectively • Hypertension • Contraindicated • GI disturbances Drug to Drug • do not stop taking this
inhibits b- • Chronic angina with sinus • Sleep disturbances Increased risk of myocardial drug unless instructed
adrenergic pectoris bradycardia • Head ache depression with verapamil, to do so by the health
receptors but has • Use cautiously with • Dizziness diltiazem, and class I care provider
little or no effect diabetes or • weakness antiarrhythmic • swallow tablet whole;
in b2 receptors thyrotoxicosis; do not wet, crush, or
except in high asthma or COPD Drug to Lab test chew them
dose • possible false results with
glucose or insulin tolerance
test(oral)
 OMEPRAZOLE
Brand Name: Losec Dosage: 40mg
Drug Class: Antisecretory, Proton Pump Inhibitor Route of Administration: IV OD
Pregnancy Category: C

MODE OF INDICATIONS CONTRA- ADVERSE DRUG INTERACTION HEALTH

ACTION INDICATIONS REACTION TEACHING/
NURSING
CONSIDERATION
Gastric acid- • short-term • Contraindicated • GI disturbances Drug to Drug • Take the drug before
pump inhibitor: treatment of active with • constipation • Increased serum levels and meal, swallow capsule
suppresses duodenal ulcer hypersensitivity to • Head ache potential increase in whole; do not open,
gastric acid • treatment of omeprazole or its • Dizziness toxicity of crush, or chew them
secretion by GERD component • Weakness benzodiazepines, • Have regular medical
specific • short-term phenytoin, warfarin; if follow-ups visits
• Abdominal pain
inhibition of the treatment of active these combinations are
hydrogen- benign gastric used, monitor patient
potassium ulcer closely
ATPase enzyme
system at the
secretory surface
of the gastric
parietal cell;
blocks the final
step to acid
production
 SUCRALFATE
Brand Name: Dosage: 1gm tab q6
Drug Class: Antiulcer Route of Administration: Oral
Pregnancy Category: B

MODE OF INDICATIONS CONTRA- ADVERSE DRUG INTERACTION HEALTH

ACTION INDICATIONS REACTION TEACHING/
NURSING
CONSIDERATION
Forms an ulcer- • short-term • Contraindicated • diarrhea Drug to Drug • Take drug on empty
adherent treatment of with allergy to • constipation • Decreased serum levels and stomach, 1 hr before or
complex at duodenal ulcers, sucralfate, chronic • Head ache effectiveness of phenytoin, 2 hrs after meal and at
duodenal sites, up to 8 weeks renal failure or • Dizziness ciprofloxacin, norfloxacin, bedtime
protecting the • maintenance dialysis • nausea digoxin, ketoconazole, • Monitor pain, give
ulcer against therapy for tetracycline, theophylline, antacids to relieve pain
• rash, pruritus
acid, pepsin, and duodenal ulcers at penicillamine, warfarin • If you are also taking
bile salts, thereby reduced stage antacids for pain relief,
promoting ulcer after healing do not take antacids 30
healing; also • Treatment of oral minutes before or after
inhibits pepsin and esophageal sucralfate
activity in gastric ulcers due to
juices irritation,
chemotherapy,
and sclerotherapy.