VIII.

Pathophysiology

Pathophysiology of Community Acquired Pneumonia

Airborne droplets -
Precipitating Factor Predisposing Factor
Organisms (bacterial, viral)
1. Exposure to streptococcus pneumonia
1. 50 years old
chemical and that contracted by
2. Filipino
bacterial agents. breathing 3. history of
smoking, and
2. Hospitalizations drinking alcohol
Invasion of infection to
because of Enters nasal passage, 4. nature of work
the Blood vessels in the
malaria. pharynx, larynx and
lung causing WBC and
trachea.
other defenses to come
as a result blood vessel
becomes inflamed
host defense wasand
cause leakage on it.
Diminished or altered
by underlying diseases
and to unknown cause.
Causing these blood, debris, wbc and
other defences accumulated to the tend to become
alveoli and fill the normally air- solid because of
containing spaces. the debris and fluid
collection
Infectious particle lies on This may also be
oropharynx w/c inflamed bloodborne organisms that
Itchy sensation and further result to enter the pulmonary
on the throat circulation and are trapped
weakness or altered
This results in less in the pulmonary capillary
Increase of mucus
host defense bed, becoming a potential
area for exchange of production and
oxygen and carbon source of pneumonia.
mucus is sometimes
dioxide. tinged the blood

Patient is now deprived

Failure of the upper respiratoryObstruction on the
of oxygen tract to prevent infectious airway.
particle to reach the sterile
lower part of the lungs

Lungs Difficulty of breathing,

become inflamed.
tachypnea, coughing
reflex.

Further leads to general

weakness
causes the protein rich fluidbecause of dec.
to seep into alveoli.
WBC fighting the infection also
tissue fill the alveoli.
perfusion