NAME OF THE GENERAL SPECIFIC INDICATION CONTRAINDICATION ADVERSE NURSING RESPONSIBILITIES

DRUG ACTION ACTION EFFECT

Amoxicillin Antibiotic Semisynthetic 1.ear , nose 1.A history of allergic 1.hyperse ADMINISTRATION/STORAGE
500 mg TID 1 broad throat reaction to any of the nsitivity
cap spectrum infections penicillins 1.Child’s dose should not exceed maximum adult dose.
penicillin due to 2.nausea
Pregnancy closely Streptococc 2.  renal impairment and 2.Client qith GFR of 10-30mL/min should receive 250 0r 500 mg
category B related to us specie, S. omitting q12h, depending on severity of infection. Those on hemodialysis
ampicillin. Pnumoniae, 3. PKU should receive 250 0r 500 mg q 24 hr, depending on infection
Bind to Staphylococ (phenylalanine- 3.gastritis severity; should receive an additional dose both during and at
penicillin- cus specis, containing forms) end of dialysis.
binding or 4.stomati
proteins (PBP- Haemophilu tis 3.Dry powder stable at room temperature for 18-30 months;
1 and PBP-3) s influenza. reconstituted suspension stable 1week at room temperature and
in the at 2 weeks at 2-8 C.
cytoplasmic 2.GU
membranes infections ASSESSMENT
of bacteria, due to 1.List reasons for therapy; C&S results. Identify onset, synptoms,
thus inhibiting Eschirichia severity, location, other associated factors.
cell wal coli, Porteus
synthesis. Cell mirabilis, or 2.Assess for previous reactions to penicillins, cephalosporins or
division and Enterococcu other antibiotics.
growth are s faecalis.
inhinited. 3.Obtain/monitor CB, renal and LFTs.
Destroyed by 3.Skin and
penicillinase, skin CLIENT/FAMILY TEACHING
acid stable, structure
and better infections 1.Take entire prescription; don’t stop if feeling better; creates
absorbed due to antibiotic resistance.
than Streptococc
ampicillin. us species, 2.For school-age child space evenly 24-hr period; give before
Staphylococ school, upon arrival home, at bedtime.
cus species
or E.coli. 3.Chewable tablets available for children; may be taken with
food.
4.Lower
respiratory 4.If using tablet for oral suspension, mix 1 tablet in about 10 mL
tract of water. Drink entire mixture, rinse with small amount of water,
infections. and drinkcontents to ensure entire dose is taken. Do not chew or
awllow tablets.
5.Acute
uncomplicat 5. place pediatric drops directly on child’s tonguw to swallow.
ed May add to formula, milk, fruit juice, water, ginger ale or cold
gonococcal drinks; must be taken immediately and comsumed completely.
infections.
6. Report unusual symptoms e.g bruising, bleeding, sore throat,
6.In rash, diarrhea, worsening of symptoms or lack of response.
combinatio
n with OUTCOMES/EVALUATE
omeprazole
or 1.Resolution of infection; symptomatic improvement
lansoprazol
e and
clarithromy
cin or
metronidaz
ole to treat
duodenal
ulcers.
 NAME OF THE GENERAL SPECIFIC ACTION INDICATION CONTRAINDICATION ADVERSE EFFECT NURSING RESPONSIBILITIES
DRUG ACTION
Mefenamic Acid Nonsteroidal Inhibition of 1. Relief of 1. Contraindicated CNS: headache,
500 mg, 1 tab Anti- prostaglandin moderate pain with dizziness, Administration/ Storage
for pain 3x a day inflammatory synthesis when therapy hypersensitivity to somnolence, 1. Refrigerate
Drugs will not mefenamic acid. insomnia, fatigue, suspension after
exceed one 2. Use cautiously tiredness, tinnitus, reconstitution;
week with asthma, renal ophthalmic effects discard after 14
2. Treatment of or liver days.
primary dysfunction, PUD, Dermatologic: rash, 2. If total daily dose is
dysmenorrhea GI bleeding, pruritis, sweating, more than 4 grams,
. hypertension, CHF, dry mucus use parenteral
pregnancy, membranes, drugs.
lactation. stomatitis 3. Continue for atleast
10days for B-
GI: nausea, hemolytic
dyspepsia, GI pain, streptococcal
diarrhea, vomiting, infections.
constipation, 4. May reduce dosage
flatulence with impaired renal
function; or increase
GU: dysuria, renal for severe
impairment infections. Drug
action can be
Hematologic: prolonges by
bleeding, platelet concurrent use of
inhibition with probenecid.
higher doses, 5. The tablets for oral
neurotropenia, suspension are used
pancytopenia, ro prepare
thrombocytopenia, individual 5-ml
agranulocytosis, doses.
granulocytopenia, 6. Store capsules,
aplastic anemia, powder for oral
decrease suspension, and
haemoglobin or tablets from 20-25 C
hematocrit, bone
marrow depression, Assessment
menorrhagia 1. Note reasons for
therapy, seerity of
Respiratory: infection,
dyspnea, characteristics of
hemoptysis, S&S, culture results.
pharyngitis, 2. Monitor CBC, renal
brocnhospasm, and LFTs; reduce
rhinitis dose with renal
dysfunction.
Other: peripheral
edema,
anaphlactoid Client/ family teaching
reactions to 1. Take as
anaphylactic shock. directed/complete
prescritption; may
take with meals for
GI upset. Shake the
reconstitutes
suspension well.
Refrigerate
suspension; discard
after 14 days.
2. Consume 2-3L/day
of fluids to prevent
 dehydration.
3. Report adverse
effects, rash,
diarrhea, yellow
discoloration of the
skin/eyes, or
lack of response.
 Dianostic Test Results Normal Values Clinical Significance

Hematology  Hemoglobin – 101 g/L 120 – 160 g/L Decreased in various anemias, pregnancy, severe or prolonged
hemorrhage, with excessive fluid intake
Increased in polycythemia, chronic obstructive pulmonary
disease, failure of oxygenation because of CHF and normally in
people living at high altitudes.

 Hematocrit – 0.32 0.36 - 0.46 Decreased in severe anemias, anemia of preganancy, acute
massive blood loss
Increased in erythrocytosis of any cause and in dehydration or
hemoconcentration associated with shock.

 WBC – 10.6 Increased –

Decreased –

 Neutrophil – 0.77 0.45 – 0.65 Increased with acute infections, trauma or surgery, leukemia,
malignant disease, necrosis
Decreased with viral infections, bone marrow suppression,
primary bone marrow disease

 Lymphocyte – 0.23 0.20 – 0.35 Increased with infectious mononucleosis, viral and some
bacterial infections, hepatitis;
Decreased in aplastic anemia, SLE, immunodeficiency including
AIDS