i $s@

SOMA IINLLTH ASSOCIATION OF AUSTRALIA LIMITED

UNDER-INVESTIGATION OF SYMPTOMS IN CHRONIC FATIGITE SYNDROMB (CFS) AND MULTTPLE CTmMTCAL SENSrrnVrrY SYNDROMB (MCSS). Statement by Dr C M Reading: B.Sc., Dip.Ag.Sci.,MBB.S.,F.R.A.N.Z.C.P.,A.C.N.E.M.
Since 1980I have treated over two,thousand patients for CHRONIC FATIGUE SYNDROME and well over a hundred for MULTIPLE CHEMICAL SENSITIVITY. All these patients, when thoroughly investigated, showed food and chemical sensitivitiet / intolerances on the CYTOTOXIC TEST, especially to cow's milk, gluten-containing grains, legumes and beans, all of which can cause severe malabsorption state for vitamins, minerals, amino acids, etc. These patients tend to have severe nutrient deficiencies due to malabsorption, and are usually low in Vits. BL, 82rB6, C, A, Folic Acid and, less often, B 1"2. They often have anaemia due to the above deficiencies but may hav,e sideropaenia - low iron without anaemia. Many have low serum zinc, and hair analysis shows low calciurn, magnesium, manganese, molybdenum, iron, chromium, zinc, selenium and cobalt, raised copper and aluminum, and unsatisfactory lead, mercury and nickel levels. (The Cytotoxic Test is accepted by the LANCET, Letter, January 24,1987.) The glare/photophobia so often observed in CFS patients indicates low iron, low Retinol A and low Zinc hence white dots in nails often, despite a normal haemoglobin/fiIm, and thus not anaemia. Many patients also have raised IgE and a host of inhalant allergies to pollens (grass, weeds, trees - pollinosis), moulds, mites, etc., as well as food allergies, and are sensitive to fumes, chemicals, perfumes, petrol, etc.

Most CFS patients have missed coeliac disease (nine out of ten in a row, diagnosed as CFS by a leading Sydney hospital - POW) and missed because most psychiatrists do not routinely have measurements done of Endomysiat IgA, Gluten IgA and ltgG or alpha-gliadin IgA and IgG, reticulin antibodies and IgM to see if these are raised, nor do they look for low C3, C4 and raised immune complexes as seen in coeliac disease, IgM can be raised-to-low also in coeliac disease. An extremely high percentage of CFS/MCSS patients are MISSED COELIACS and about 5To TTeMISSED SLB -which is not usually even considered. AII CFS patients should be tested for ANF and, if positive, then do dsDNA; and, if not raised (diagnosing SLE), then ENA screen, C3, C4 complements, immune complexes, anti-lymphocyte antibodies, immunoglobulins (IgA, IgM, IgG) and if any of the above are abnormal (despite a negative ENA screen) then a skin biopsy on unexposed skin with immunofluorescent technique to
confirm/diagnose SLE.

Many patients with CFS show white dots in their nails which is" associated with low 86, zinc and pyroluria with kryptopyrroles in the urine, and if these levels are high there is high risk for acute intermittent poryphyria, especially if reacting to drugs , chemicals, fumes, perfumes and chlorpyrifos/pesticides and herbicides which can cause a flare-up of porphyria, as also can barbiturates, sulphnamides, neuroleptics, etc.

Most CFS/MCSS patients have severe autoimmune disease (as seen with SLE, coeliac disease, and show vasculitis, autoimmune neuritis,etc.) and need a gluten-free diet or a diet gastritis, thyroidiotis, ,cholangitis, Thbse patients, in my experience, have severe cow's milk alpha-casein, +/design to reverse SLE. */- beta-lactalbumin, sensitivity/intolerance when antibodies to these peptides of cow's alpha-lactalbumin, (cont.) milk are measured - as well over a thousand patients since 1980.

Under-investigation of symptoms in CFS and MCSS: (cont')

with egg and beef When intolerant/hypersensitive to cow's milk albumin-globulin, then these cross-react albumin and globulin, and also need to be avoided. In addition, because of the suppressed/compromised are at risk for opportunist immune system and often low cortisol DHEA, MCSS patients (often being coeliacs) pylori, chlamydia pneumoniae and pathogenes such as candida albicans, mycoplasma, rickettsia, helicobacter These pathogens need to be identified campylobacter jejuni aggravating/aomplicating their treatment.
and killed off.

patients and show High levels of aluminium, copper and , Iess often, lead and mercury are seen in CFS/MCSS +/- low serum DHEAST i.e- adrenal exhaustion, especially on hair analysis. They also have low serum cortisol Most have a marked tendency to hypoglycaemia and need to eat protein and many are hypothyroid. are common in my two-hourly in order not to becorne hypyglocaemic. Severe amino acid deficiencies 83 in addition to nutrient experience (also refer Newcastle University research) and may have low vit in CFS/MCSS patients (work deficiencies mentioned above. High levels of pesticides/herbicides are common They also have abnormal metabolites in of Dr Mark Donohoe and Tim Rob,erts et al of Newcastle University).
the urine (and Kryptopyrotles / pynoluria ).

(a)
have

made a rapid recovery with Hospital crawled out of hospital and caught a taxi to Manly Flospital where she 83 treatment, etc.

'hysterical' and not allowed to Shore Vit. 83. (Pellagra is a Vit. B3 deficiency)' One patient at the Cummins Unit of Royal North

have seen moribund patients

with

severe pellagra who were called

CFS picture Another with severe pallor/weakness at Camperdown Children's Hospital with severe to alpha-casein, alphawas called hysterical until I showed the treating psychiatrist she had antibodies and milk products they lactalbumin, proving she had severe cow's milk sensitivity/intolerance. The ice-cream off all diary products she were giving her out of kindness were making her seriously ill and moribund.

(b)

rapidly recovered.
as schizophrenic Another patient with tarclive dyskinesia due to Serenace, and wrongly diagnosed for many months on extra nutrients and instead of toxic encephalopathy/chloropyrifos poisoning, etc., did well she came into contact with food allergy-free diet, etc., and no neuroleptics at all, or minimal Melleril, until given high amounts- of more spraying with pesticides/herbicides. She was hospitalized and -neuroleptics, IMr neuroleptic weekly for her Acute making her very illr r saw her regularly while she was on high dosage her treatment Brain Syndrome which had severe side-effects, agitation, depression. This was to be off the neuroleptics she rapidly indefinitely, all her complaints about side-effects being ignored. Each day minimal Melleril' The improved. Fortunately, she agaiin did well on extra nutrients, special diet and in cFS and MCSS is overwheliltr evidence supporting increased investigation intb causes of syrnptoms

(c)

(originally published soMA NEWSLETTER, October 1999,Vo1.21,

No'2'

Reprint by request')