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INDEX NURS 2236 Clinical Form 3: Clinical Medications Worksheet

(You will need to made additional copies of these forms)


Generic Trade Classification Dose Route Time/Frequency
Name Name lipid-lowering
simvastatin Zocor agents 5-10mg PO Daily/evening

Peak Onset Duration For IV meds, compatability with IV drips and/or solutions
unknown unknown unknown
Why is your patient taking this medication?

Mechanism of action and indications Nursing Implications (what to focus on)


Adjunct to dietary therapy in the management of Contraindications/warnings/interactions Hypersensitivity, Cross-sensitivity
primary hypercholesterolemia and mixed dyslipidemias among agents, sepsis, acute hypotension, major surgery, trauma, severe
Reduction of lipids/chlesterol reduces the risk of MI and metabolic disturbances, endocrine or electrolyte disorders, uncontrolled
stroke, and decreases the need for bypass procedures/ seizures, active liver disease, pregnancy, lactation, use of gemfibrozil or azole
angioplasty. use of nelfinavir or ritonavir, alcohol, renal impairment, visual, myopathy,Asian
Lowering of total LDL cholesterol, Increase HDL and Common side effects dizziness, headache, insomnia, weakness, rhinitis,
decrease VLDL cholesterol and triglycerides. Slowing lovastatin: blurred vision, bronchitis, abdominal cramps, constipation, diarrhea,
of progression of coronary artery disease with resultant flatus, heartburn, altered taste, drug-induced hepatitis, dyspepsia, elevated
decrease in MI/Stroke and need for myocardial liver enzymes, nausea, pancreatitis, impotence, rhabdomyolysis, arthralgia,
revascularization arthritis, myalgia, myositis
Interactions with other patient drugs, OTC, or herbal Lab value alterations caused by medicine
medicines (ask patient specifically)
CYP3A4 inhibitors, bile acid sequestrants, amiodarone
cyclosporine, gemfibrozil, clofibrate, diltiazem verapamil,
erythromycin clarithromycin telithromycin, nefazodone, Be sure to teach the patient the following about this medication
niacin, azole, antifungal agents, nelfinavir, ritonavir ( Don't dring more than 1 qt/day grapefruit, use meds in conjuction with diet.
(combined with clofibrate or gemfibrozil), warfarin exercise and stop smoking, notify physician of muscle pain, tenderness, or
propranolol, saquinavir, St. John's wort, grapefruit juice weakness occurs (especially with fever or malaise). Wear sunscreen and
(more than 1 qt/day) protective clothing, notify if pregnant, follow-up exams.

Nursing Process - Assessment Assessment Evaluation


(Pre-administration assessment) Why would you hold or not give Check after giving
Vital Signs this med? Decrease in serum LDL, VLDL, and total
Dietary history (fats), Ophthalmic exams, Muscle tenderness, high CPK levels, cholesterol levels.
myopathy Increase in HDL cholesterol levels
Decrease in triglyceride levels
Slowing of the progression of coronary
artery disease

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