Systematic review / meta analysis(PCIJ)

1
0:

P: Patient, Population, or Problem

I: Intervention, Prognostic Factor, or Exposure

C: Comparison

O: Outcome

(usefulness) = {(relevance) X (validity)} / (work)

1: (relevance)
a.

-> Yes / No
b.

-> Yes / No
c.

DOEPOEM
-> Yes /
No
d.

->
Yes / No
e.

-> Yes /
No
a-e No
: (validity)
a.

-> Yes /
No
b.
-> Yes / No
c.

-> Yes / No
d.
(test for heterogeneity)meta-analysis-> Yes
/ No
e.
publication bias -> Yes / No
f.
LOE (Level of Evidence)
->

g.
COI (Conflict of Interest)-> Yes / No
a cmethoddresult

a.
,

b.
: CI

c.

Systematic review / Meta analysis Page 1 of 2

T. Okada@PCIJ

9.14.11


meta analysis
Forest plot (blobbogram)

funnel plot

http://holfordwatch.files.wordpress.com/2008
/04/illusblobbogram.gif

funnel plot

test for heterogeneity

QUOROM(1999)->PRISMA statement(2009)

1.
QUOROM
http://homepage3.nifty.com/cont/QUOROM_Statement/QUOROM_chk_Jap.pdf
2.
Moher D, Cook DJ, Eastwood S, et. al. Improving the quality of reports of
meta-analysis of randomised controlled trials: the QUOROM statement. The
Lancet 1999; 354: 1896-900
3.
Liberati et al. The PRISMA statement for reporting systematic reviews and
meta-analyses of studies that evaluate healthcare interventions: explanation
and elaboration. BMJ 2009; 339:b2700 doi: 10.1136/bmj.b2700 (Published 21
July 2009)
4.
. EBM.
5.
JAMA Users guide to the Medical Literature. 2008
6.
Sutton AJ, Duval SJ, Tweedie RL, Abrams KR, Jones DR. Empirical
assessment of effect of publication bias on. Database. 2000;320(June):15741577.
7.
3.4 http://spell.umin.jp/BTS_SR3.4.pdf
8.
Clinical Journal Club 8. Meta-analysis () 1
http://www.med.osaka-u.ac.jp/pub/kid/clinicaljournalclub8.html

Systematic review / Meta analysis Page 2 of 2

T. Okada@PCIJ

9.14.11