Professional Documents
Culture Documents
Jennifer J. Mananes, MD
Resident Department of Pathology DLSUMC
Alteration in lung expansion (Atelectasis) slide 107 Diseases of vascular origin Chronic Passive Congestion 79 Hemorrhagic infarction 104 ARDS 190 Pulmonary infections Bronchopneumonia 70 Tuberculosis 72 Aspergillosis 185 Tumors Primary Moderately differentiated squamous cell carcinoma 300 Bronchogenic carcinoma, large cell undiffiferentiated 109 Bronchial carcinoid 213 Secondary Metastatic Choriocarcinoma, metastatic 165
Greek words ateles and ektasis, ~ incomplete expansion. Collapse/ compression of a previously inflated lung.
Atelectasis
What x-ray finding differentiates obstructive from compressive atelectasis?
Brown induration
slide 79
Hemorrhagic infarction
slide 104
Hemorrhagic infarction
ARDS 190
ARDS
Bronchopneumonia slide 70
Bronchopneumonia
Guide question: On the basis of the microscopic pathology, explain the occurrence of rales in bronchopneumonia.
Miliary tuberculosis
Note the tubercles composed of epithelioid cells, Langhans giant cells, and lymphocytes Type of inflammation? Necrosis? Etiology?
Aspergillosis
slide 300
Note the nests of tumor cells surrounded by delicate fibrocollagenized connective tissue stroma Cells are small and uniform in size with scanty cytoplasm/ uniform cytologic pattern What is the histogenesis of this tumor? What is carcinoid syndrome?
Choriocarcinoma, metastatic
Cytotrophoblast vs Syncytiotrophoblast Rounder with vesicular nuclei and prominent nucleoli Spindlly, irregularly-shaped, and hyperchromatic nuclei
Guide Question---Explain why the liver and the lungs are the two most frequently involved organs in hematogenous metastatic carcinoma.
Emphysema
Bronchiectasis
Bronchiectasis