Professional Documents
Culture Documents
PLACENTAL
ABNORMALITIES
Penyaji: Dr. Iman Ruansa
Pembimbing: Dr. H. Nuswil Bernolian SpOG(K)
Placental Tumors
Gestational Trophoblastic Disease
These pregnancy-related trophoblastic
proliferative abnormalities are discussed
in Chapter 20 (p.396).
Chorioangioma
Have components similar to blood vessels
and stroma of the chorionic villus
Also called chorangioma
Have an incidence of approximately 1
percent (Guschmann, 2003)
In some cases, maternal serum alphafetoprotein (MSAFP) levels may be
elevated with these tumors, an important
diagnostic finding
Meconium Staining
Fetal passage of meconium before or
during labor is common with cited
incidences that range from 12 to 20
percent (Ghidini, 2001; Oyelese, 2006;
Tran, 2004).
Importantly, staining of the amnion can be
obvious within 1 to 3 hours, but its
passage cannot be timed or dated
accurately (Benirschke, 2012).
Chorioamnionitis
Normal genital-tract flora can colonize and infect
the membranes, umbilical cord, and eventually the
fetus.
Bacteria most commonly ascend after prolonged
membrane rupture and during labor to cause
infection.
Organisms initially infect the chorion and adjacent
decidua in the area overlying the internal os.
Subsequently, progression leads to full-thickness
involvement of the membranes-chorioamnionitis.
Coiling
Although cord coiling characteristics have been reported,
these are not currently part of standard sonography
(Predanic, 2005a).
Usually the umbilical vessels spiral through the cord in a
sinistral, that is, left-twisting direction (Lacro, 1987).
The number of complete coils per centimeter of cord
length has been termed the umbilical coiling index
(Strong, 1994).
A normal antepartum index derived sonographically is
0.4, and this contrasts with a normal value of 0.2 derived
postpartum by actual measurement (Sebire, 2007).
Vessel Number
Occasionally, the usual arrangement of two thick-walled
arteries and one thin, larger umbilical vein is altered.
The most common aberration is that of a single
umbilical artery, with a cited incidence of 0.63 percent
in liveborn neonates, 1.92 percent with perinatal deaths,
and 3 percent in twins (Heifetz, 1984).
The cord vessel number is a component of the standard
prenatal ultrasound examination (Fig. 6-5).
Identification of a single umbilical artery frequently
prompts consideration for targeted sonography and
possibly fetal echocardiography.
FIGURE 6-5 Two umbilical arteries are typically documented sonographically in the
second trimester. They encircle the fetal bladder (asterisk) as extensions of the superior
vesical arteries. In this color Doppler sonographic image, a single umbilical artery,
shown in red, runs along the bladder wall before joining the umbilical vein (blue) in the
cord. Below this, the two vessels of the cord, seen as a larger red and smaller blue
circle, are also seen floating in a cross section of a cord
segment.
Insertion
The cord normally inserts centrally into the placental disc, but
eccentric, marginal, or velamentous insertions are variants.
The latter two are clinically important in that the cord or its vessels
may be torn during labor and delivery.
Of these, marginal insertion is a common variantsometimes
referred to as a battledore placentain which the cord anchors at
the placental margin.
These are more frequent with multifetal pregnancy, especially those
conceived using assisted reproductive technology, and they may be
associated with weight discordance (Delbaere, 2007; Kent, 2011).
This common insertion variant rarely causes problems, but it
occasionally results in the cord being pulled off during delivery of
the placenta (Liu, 2002).
FIGURE 6-6 Velamentous cord insertion. A. The umbilical cord inserts into the
membranes. From here, the cord vessels branch and are supported only by membrane
until they reach the placental disk. B. When viewed sonographically and using color
Doppler, the cord vessels appear to lie against the myometrium as they travel to insert
marginally into the placental disk, which lies at the top of this image.
Vasa Previa
This is a particularly dangerous variation of velamentous insertion in
which the vessels within the membranes overlie the cervical os.
The vessels can be interposed between the cervix and the presenting
fetal part.
Hence, they are vulnerable to compression and also to laceration or
avulsion with rapid fetal exsanguination.
Vasa previa is uncommon, and Lee and coworkers (2000) identified it
in 1 in 5200 pregnancies.
Risk factors include bilobate or succenturiate placentas and
secondtrimester placenta previa, with or without later migration
(Baulies, 2007; Suzuki, 2008b).
It is also increased in pregnancies conceived by in vitro fertilization
(Schachter, 2003).
FIGURE 6-7 Vasa previa. Using color Doppler, an umbilical vessel (red
circle) is seen overlying the internal os. At the bottom, the Doppler
waveform seen with this vasa previa has the typical appearance of an
umbilical artery, with a pulse rate of 141 beats per minute.
Vascular
Cord hematomas are uncommon and have
been associated with abnormal cord length,
umbilical
vessel
aneurysm,
trauma,
entanglement, umbilical vessel venipuncture,
and funisitis (Gualandri, 2008).
They can follow varix rupture, which is
usually of the umbilical vein.
They are recognized sonographically as
hypoechoic masses that lack blood flow.
TERIMA KASIH