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Digestive Tract
DIGESTIVE SYSTEM:
the main idea/major functions
Cell Growth
Cell Repair
Cell Maintenance
Production of hormones, enzymes, etc.
Carbohydrates :
Enzyme = amylase
Polysaccharides monosaccharides
Disaccharides monosaccharides
Proteins:
Enzyme = protease
amino acids
Figure26.2
Peristalsis
how material is
moved/propelled through
the digestive tract
requires both a circularly
and a longitudinally
arranged layer of muscle
Digestive Tract
12. jejunum
1. mouth
2. oral cavity
salivary
glands
13. ileum
3. fauces
4. oropharynx
5. laryngopharynx
7. esophagus
8. lower esophageal sphincter
(cardiac)
9. stomach
2. oral cavity
13. ileum
4. oropharynx
5. laryngopharynx
6. upper esophageal sphincter
7. esophagus
8. lower esophageal sphincter
(cardiac)
9. stomach
10. pyloric sphincter
11. duodenum
simple
columnar
simple
columnar
3. fauces
stratified squamous
1. mouth
Figure26.2
= movement/propulsion
= mechanical digestion
Figure26.3
Oral Cavity
Lined with stratified
squamous
Mechanical digestion by teeth
Chemical Digestion by
salivary and intrinsic enzymes
and
salivary amylase & lipase
approximate pH ~ 7
Sensation: taste and texture
Propulsion (with tongue)
Figure26.5
Teeth
Mechanically Digest
Know parts as per lab
Incisors: snip/clip/cut
Canines: tear
premolars: crush and
grind
molars: better crushers
and grinders
Figure26.4
Digestive Tract
12. jejunum
2. oral cavity
13. ileum
4. oropharynx
5. laryngopharynx
6. upper esophageal sphincter
7. esophagus
8. lower esophageal sphincter
(cardiac)
9. stomach
10. pyloric sphincter
11. duodenum
simple
columnar
simple
columnar
3. fauces
stratified squamous
1. mouth
Figure26.3
Structure:
Lined with stratified squamous
Pharyngeal constrictor muscles (skeletal
muscles) along posterior wall for swallowing
Figure26.9
Submucosa
Dense CT, larger vessels,
nerves/submucosal plexus that innervates/regulate mucosa and submucosa
Serosa OR adventitia
outer most layer
serosa = visceral peritoneum
adventitia=dense CT
Figure26.10
Esophagus
submucosa
glands that produce mucous that
lubricates
Muscularis
inner circular layer
transitions from skeletal to smooth
Adventitia
Lower Esophageal Sphincter
poorly defined muscular thickening at
end of esophagus
reinforced by diaphragm
prevents movement of stomach
contents back into esophagus
Figure26.12
Stomach
Processes
Mechanical digestion
churning
involves inner oblique layer
Denaturing proteins by acids
Kills pathogens with acidity
Chemical Digestion
proteins by enzymes
pH ~2.5-4.5
minimal absorption
alcohol and some lipid soluble
substances
soupy mixture/contents of
stomach = chyme
Figure26.12
Stomach
Mucosa:
Simple Columnar
Rugae
allow expansion
Submucosa
unnotable
Muscularis
inner oblique layer
intermediate circular
outer longitudinal layer
Serosa
Unnotable
Pyloric Sphincter
well defined sphincter at junction with
duodenum
Controls emptying of stomach
Stomach is lined by surface mucus cells/simple columnar and inward projection that form
gastric pits gastric glands
Figure26.13
Figure26.13
Intrinsic factor
absorption of B12
Chief Cells
pepsinogen
inactive enzyme
(gastroendocrine)
gastrin (released due to pH)
chemical regulation of digestive function
E.g., Increased parietal and chief cell secretion
E.g., Increased gastric motility
Figure26.14
Small Intestine
Main Functions:
Structure:
3 regions:
doudenum (10, retroperitonealnot surrounded by peritoneum)
jejunum ~ 8, most absorption and digestion; has serosa
ileum ~ 12, has serosa
4. microvilli
Figure26.15
Figure26.15
Small Intestine
Mucosal epithelium
Simple columnar
thin enough to pass through, large enough to be active
absorptive cells
intrinsic enzymes for chemical digestion
absorption
goblet cells
lubricating mucus that protects against acidic chyme
(entero)endocrine cells
regulatory hormones
intestinal crypts:
source of new columnar cells
Also produce alkaline mucus
Neutralizes acidic chyme from stomach
External to Mucosa
capillaries and lacteals within mucosa accept absorbed nutrients
Lymphatic tissue to protect again harmful microorganisms
Figure26.16
Large Intestines
Includes:
cecum
colon
rectum
anal canal
Main Functions:
re-absorbs water to consolidate chyme into feces
but NOT main site of water absorption
Copyright The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
Ingestion
(2 L)
Gastric
secretions
(2 L)
Pancreatic
secretions
(1.2 L)
Bile
(0.7 L)
Small intestine
secretions
(2 L)
92%
absorbed in the
small intestine
6 7%
absorbed in the
large intestine
Ingestion or
secretion
Absorption
1% in
feces
(Water in feces = ingested + secreted absorbed)
Figure26.17
Large Intestines
Structure:
Mucosa: simple columnar
absorptive cells
mucus cellspredominate
to lubricate the solidifying mass of material
invaginated glands; crypts
With many mucus cells
muscularis
longitudinal layer concentrated into the 3 teniae coli
muscle tone (partial contraction) causes L.I. to gather and produce
haustra
Rectum
Last 6 of digestive tract
Mucosa of simple columnar that transitions to stratified
squamous by beginning of anus (the opening out of rectum)
Submucosa and lamina propria rich in blood vessels
hemorrhoids
retroperitoneal
Anus
Passageway out of rectum
Figure26.7
STRUCTURE
Parietal peritoneum lines the body wall
Visceral peritoneum covers surface of many abdominal organs
MESENTERY
Mesentery is a the visceral peritoneum folded back on itself with
no organ in between.
contain blood vessels
site for adipose tissue deposition
Mesenteries
NOTE: dont memorize these unless study guide says to.
Figure26.8
Pancreas
Figure26.20
Pancreas
Digestive Function:
Pancreatic Juice
Created by acini cells of pancreas
Contains enzymes that break down:
carbohydratespancreatic amylase
proteinsproteases
lipidslipases
Nucleasesnucleic acids
Enters the duodenum via duodenal papilla
pancratic ducthepatopancreatic ampullar sphincter/duodenal papilla
Regulated by hormones:
Secretin--from
Cholecytokinin (CCK)--from
endocrine function
releases insulin (reduces blood sugar and encourages cells to store away nutrients)
releases glucagon (increases blood sugar and encourages cells to release stored energy)
Figure26.18
Liver
Liver Functions
Stores and Releases glucose (only organ/tissue that can
release glucose)
to stabilize blood glucose
Inferior vena
cava
Aorta
Heart
Hepatic veins
Central vein
3
Hepatic cords
composed
of hepatocytes
Hepatic duct
Hepatic portal
vein
Hepatic artery
Liver lobule
Portal
triad
Bile
canaliculi
Hepatic
sinusoid
Hepatic
duct branch
Hepatic portal
vein branch
Hepatic
artery branch
Hepatic
ducts
Hepatic portal
vein
Hepatic
artery
Hepatic duct
Porta
of liver
2
Bile
Nutrient-rich,
oxygen-poor,
blood
1
Oxygen-rich
blood
Inferior view
Oxygen-rich
blood
Small
intestine
Portal
triad
Bile
Produced by liver
Stored in Gallbladder
lined by smooth muscle
absorbs water/concentrates bile (5-10x more concentrated)
Figure26.21
Bile flow
Hepatocytes
bile canaliculi
hepatic ducts
L&R hepatic ducts
common hepatic duct
common bile duct
duodenum
Cystic duct
Glossopharyngeal nerve
tongue & pharyngeal muscles
Vagus Nerve
Pharynx & esophagus
Table26.1
Table26.3
Table26.4