Critical Appraisal

Case control study

Anak Agung Eka
Ayu Diandra Sari
Dyah Saptarina
Firsandi Prasastya Fikry
Karina Komala
Lidya Yudith Priskila
Meriza Martineta
Nadiyah Wijayanthie
Sheena R Angelia

Citation
Rodriguez-Campello A, Jimenez-Conde J, Ois A,
Cuadrado-Godia E, Giralt-Steinhauer E, Schroeder H, et
al. Dietary habits in patient with ischemic stroke : a
case-control study. PLoS ONE. 2014 ; 9 (12) : e114716.
1-14

Bagaimana cara memperoleh

kasus?
Hal 2, paragraf 1 (material and methods)
... Included patients with a diagnosis of first ever AIS
admitted to the neurologic department of Hospital Del
Mar from 2007-2010

Apakah kelompok kontrol sudah

sesuai?
Ya, sudah
Hal 3, paragraf 2 (material and methods)
patient were match (1:1) by age and sex with healthy
control freom REGICOR database... Several studies have
established that this population are homogenous in
term of cardiovascular epidemiology, and have similar
eating habit...

Apakah pengukurannya valid dan

reliable?
Ya
Hal 3 (material and methods, Dietary habit)
AIS neurologist, CT scan, MRI
SFFQ validated for this population

Apakah metode statistiknya

dijelaskan?
Ya
hal 4, paragraf 1 ( statistical consideration)
... Normality by Kolmogorov-Smirnov test and ShapiroWilk test.
Those with non normal distribution were logtransformed to allow the use of parametric test.
...Unpaired T-test and Chi Square test were used for
continous variable and categorical variables,
respectively.
Multivariat analysis included...

Apakah kejadian yang tidak

diharapkan muncul pada penelitian
ini?
Tidak ada laporan

Apakah karakteristik data

dijelaskan?
Ya, hal 5 paragraf 3 ( result ), dan tabel 1

Apakah jumlah subjek berubah?

Tidak
Jumlah subjek kasus 300
Jumlah subjek kontrol 300
jumlah tetap sama sejak awal hingga akhir penelitian

Apakah ada data yang dianalisis

tetapi diluar dari tujuan penelitian?
Tidak ada
Hal 7 tabel 2

Apakah hasil yg signifikan dinilai?

Ya, hal 5 paragraf 4 ( result ), tabel 2
We observed a higher caloric intake in stroke patient
than in control... , respectively ( p = 0,001 )
... Higher intake of protein ( p< 0,001), total cholesterol
(p=0,001), breade food ( p=0,001), and lower
consumption of yoghurt with lactobacillus sp (p=0,002)

Apa arti dari temuan utama ?

Hal 6, paragraf 1 ( Discussion)
... The differencies in diet included higher total caloric,
protein, and total cholesterol intake, and lower
consumption of probiotic yoghurt among stroke patient,
compare to control. Stroke patient also ate more
breaded food.

Di manakah terdapat bias ?

Information bias SFFQ

Apakah ada confounding?

Ya, hal 11 paragraf 5 ( discussion)
Sosioekonomi, physical activity
Age bukan confounding karena sudah di matching

Apakah hasil yg tidak signifikan di

interpretasikan?
Hal 12 di discussion paragraf 2
Hasil yang tidak signifikan dijelaskan atau tidak?

Apakah ada efek- efek yang

diabaikan?
Tidak laporkan

Bagaimana hasil penelitian ini bila

dibandingkan dengan penelitian
sebelumnya?
Hal
Hal
Hal
Hal

7, (discussion) paragraf 2, 3, 4
9 paragraf 2
10 paragraf 3
11 paragraf 3

Apa implikasi dari penelitian ini

terhadap praktek kedokteran ?
bisa
untuk menurunkan risiko AIS kita dapat menerapkan
diet konsumsi sayur2an, menurunkan fat, menurunkan
intake makanan manis, meningkatkan whole food dan
intake rendah garam. Karena juga ditunjang dalam
penelitian sebelumnya