AACE/ACE COMPREHENSIVE TYPE 2
DIABETES MANAGEMENT ALGORITHM
— x=
‘Martin Abrahamson, MD
Joshua | Baily, MO, FACE
Lawrence Blonde, MO, FACP FACE
Zachary. Bloomgarden, MD, MACE
Michae! A. Bush, MD
‘Samuel Dagogo-Jack, MD, DN, FRCP, FACE
Ralph A, Defronzo, MD
TASK FORCE
Alan J. Garber, MD, PhD, FACE, Chair
Daniel Einhorn, MD, FACR, FACE
Vivian A. Fonseca, MD, FACE
Jeffrey R. Garber, MD, FACR, FACE
Wi Timothy Garvey, MD, FACE
George Grunberger, MD, FACP, FACE
Yehuda Handelsman, MD, FACP.FNLA, FACE
Robert R. Henry, MO, FACE
eB Hitsch, MD
Paul S.Jelinger, MD, MACE
Janet BMG, MD, FACE
Jere l Mechanick, MD, FACP, FACE, FACN, ECNU
Paul D. Rosenblit, MD, PHD, FNLA, FACE
Guillermo Umpierrez, MD, FACE, FACETABLE OF CONTENTS
COMPREHENSIVE TYPE 2 DIABETES ALGORITHM
Il
IV.
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IX.
LIFESTYLE THERAPY
COMPLICATIONS-CENTRIC MODEL FOR CARE
OF THE OVERWEIGHT/OBESE PATIENT
PREDIABETES ALGORITHM
GOALS FOR GLYCEMIC CONTROL
GLYCEMIC CONTROL ALGORITHM
ALGORITHM FOR ADDING/INTENSIFYING INSULIN
ASCVD RISK FACTOR MODIFICATIONS ALGORITHM
PROFILES OF ANTIDIABETIC MEDICATIONS
PRINCIPLES FOR TREATMENT OF TYPE 2 DIABETESPhysical
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erry
GDS CL! lal eG
RISK STRATIFICATION FOR DIABETE
Maintain optimal weight
Calorie restriction
Plant-based dit; high polyunsaturated
and monounsaturated fatty acids
‘Avoid trans faty acids
limit saturated fatty acids
150 min/week moderate exertion
(eg. walking stair climbing)
Strength traning
Increase as tolerated
About 7 hours per night
Community engagement
Seteen for mood disorders
No tobacco products
COMPLICATIONS
Structured counseling
Meal replacement
Medical evaluation/
clearance
Medical supervision
structured
program
Screen for obstructive sleep apnea
Refer to mental healthcare professional
Behavioral therapy
Structured programs6) COMPLICATION ENTRIC MODEL FOR CARE
OF THE OVERWEIGHT/OBESE PATIENT
EVALUATION FOR COMPLICATIONS AND STAGING
Perec Cue
BMI 225 BMI = 27: Stage Sever
wiLo To MODERATE
t t t
— Treatment _{__Tieatment testy based
+ + +
Ree Physician/RD counseling, web/remote program, structured multidisciplinary program
of Complications
= >
eee
(Cera
_—
Surgical Therapy (BMI = 35)
If therapeutic targets for complications not met, intensify lifestyle, medical, and/or surgical treatment
UAE modalities for greater weight loss.PREDIABETES ALGORITHM
100-125) | IGT (140-199) | METABOLIC SYNDROME (NCEP 2001)
ae aD) WEIGHT Loss, UNNI
Pazar THERAPIES FPG > 100 | 2-hour PG> 140
ASCVD RISK FACTOR 1 PRE-DM. MULTIPLE PRE-DM
MODIFICATIONS ALGORITHM CRITERION CRITERIA
DYSLIPIDEMIA HYPERTENSION
ROUTE ROUTE, oa
or
tentrmerapaae rea) 7
omeroeppn agi 3. sro IFalycemia
eh seca see rE not normalizedS FORSGRSEMIG CONTROL
INDIVIDUALIZE G
A1C < 6.5% A1C > 6.5%
For patients without For patients with
concurrent serious concurrent serious
illness and at low illness and at risk
hypoglycemic risk for hypoglycemiaEMIC CONTROL ALGORITHM
a sc
Cee
SLF2i Tv se 7
PP.
scur2i
- 5 on
,= | MET On
basa sn
p , nse
Cotesevelan a
‘Bromocriptine OR
(
Colesevelam
Bat
SU/GLN
9
+ Bromocriptine OR
Lh ADD OR INTENSIFY
AGL INSULIN
fer to nslin Algorithm
su/atn
(|
kee eeSORITHM FOR ADDING/INTENSIFYING INSULIN 4
START BASAL (Long-Acting Insulin) INTENSIFY (Prandial Control)
Peas Eagee cry COC ey
co
Cectey age Lt
tee
Insulin titration every 2-3 days.
to reach glycemic goal:
+ Begin prandl + Begin prandil
mens insula before Insulin before
oer Cen largest meal each meal
a arte + Hfnotat goa, + 50% Basal
era progress to 50% Prandial
Injections before Top 03-05 Uikg
20r3 meals
ee eeeISK FACTOR MODIFICATIONS ALGORITHM na
DYSLIPIDEMIA aaa a oh
fice GOAL: SYSTOLIC <130,
DIASTOLIC <80 mm Hg
I tatinintoierant
‘Ty aternate statin. tower stan Aepeatipi pane Antena therapies to a
deseo ranean seat stamgnaacoring Acti snd
lowering therapies tolerance of therapy torskleves ve
reer IT cy Coord
Tg cls oe Ag gee eee =A
Dla <0 7 ifnotat goal (2-3 months)
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