Professional Documents
Culture Documents
(CKD)
Definition of CKD
Cockcroft-Gault
Men: CrCl (mL/min) = (140 - age) x wt (kg)
72x SCr
Women: multiply by 0.85
MDRD
GFR (mL/min per 1.73 m2) = 186 x (SCr x 0.0113)-
1.154 x (age)-0.203 x (0.742 if female) x (1.12 if African-
American)
The Mosteller formula
BSA (m) =
( [Height(cm) x Weight(kg) ]/ 3600)
e.g. BSA = SQRT( (cmx kg)/3600 )
High Risk for CKD
DM,HT, NS, CGN,KUB stone
exposure to nephrotoxic agent
Previous kidney disease
Autoimmune disease
Family history of renal disease
Cardiovascular disease
Elderly
Recurrent UTI
Staging in diabetes nephropathy
Risk factor for CKD progression
Blood pressure , hyperglycemia
Proteiuria
Extent of tubulointerstitial disease
Drugs : Nsaids
Vascular calcification (Cax Po4 products
>55)& , hyperphosphatemia
Dietary protein intake
History of AKI
Smoking ,Hyperlipidemia, genetic factor
Proteinuria
80
70
60
50
40
30
20
10
0
15-29 30-59 60-89 90+
Estimated GFR (ml/min/1.73 m2)
10
General population
1
0.1 Male
Female
0.01 Black
White
2534 4554 6574 85
3544 Age (years) 7584
5564
CKD management
Stage 1
specific Rx , Rx comobid,
Rx CVD& CVD risk factor
Stage 2 estimate &slow progression
Stage 3 Evaluate&Rx complication
Stage 4 preparation for RRT
Stage 5 RRT(if uremic present)
CVD risk reduction