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Remodeling
of the heart occurs, with predominantly dilatation
and a lesser
Sympathetic activation leads to the additional
degree of hypertrophy. If left untreated, pulmonary
symptoms of sweating and irritability and the
vascular resistance
imbalance between
eventually begins to rise and, by several years of age,
oxygen supply and demand lead to failure to thrive
the
shunt volume will decrease and eventually reverse to
right to left
Regurgitation through the AV valves is most
commonly encountered in patients with partial or
complete AV
Additional lesions that impose a volume load on the heart septal defects (AV canal, endocardial cushion defects). In
include regurgitant lesions ( Chapter 422 ) and the these
cardiomyopathies lesions, the combination of a left-to-right shunt with AV
( Chapter 433 ) valve
regurgitation increases the volume load on the heart and
often
leads to more severe symptoms.
Lesions Resulting in Increased Pressure Load