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Sianipar
Nicholas B. Sianipar
Nicholas B. Sianipar
Introduction
Atrial fibrillation (AF) is the most common
sustained cardiac arrhythmia, occurring in 1 2% of the general population. Over 6 million Europeans suffer from this arrhythmia, and its prevalence is estimated to at least double in the next 50 years as the population ages. AF confers a 5-fold risk of stroke, and one in five of all strokes is attributed to this arrhythmia.
Nicholas B. Sianipar
Epidemiology
AF affects 12% of the population, and this
figure is likely to increase in the next 50 years. The prevalence of AF increases with age, from <0.5% at 4050 years, to 515% at 80 years. Men are more often affected than women.
Nicholas B. Sianipar
Nicholas B. Sianipar
Tachycardiomyopathy
Cardiomyopathies
Thyroid dysfunction
Obesity
Diabetes mellitus
COPD
Nicholas B. Sianipar
Nicholas B. Sianipar
Definition of AF
The surface ECG shows absolutely irregular RR intervals (AF is therefore sometimes known as
arrhythmia absoluta), i.e. RR intervals that do not follow a repetitive pattern. There are no distinct P waves on the surface ECG. Some apparently regular atrial electrical activity may be seen in some ECG leads, most often in lead V1. The atrial cycle length (when visible), i.e. the interval between two atrial activations, is usually variable and <200 ms (>300 bpm).
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Management
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Antithrombotic management
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Antithrombotic management
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Antithrombotic management
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Antithrombotic management
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Long-term management
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Long-term management
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Long-term management
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Upstream therapy
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Activates RAAS
AF
Fibrosis
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